{"id":"https://openalex.org/W2158709077","doi":"https://doi.org/10.1152/physiologyonline.1996.11.6.255","title":"Mechanisms of Obesity-Induced Hypertension","display_name":"Mechanisms of Obesity-Induced Hypertension","publication_year":1996,"publication_date":"1996-12-01","ids":{"openalex":"https://openalex.org/W2158709077","doi":"https://doi.org/10.1152/physiologyonline.1996.11.6.255","mag":"2158709077"},"language":"en","primary_location":{"id":"doi:10.1152/physiologyonline.1996.11.6.255","doi":"https://doi.org/10.1152/physiologyonline.1996.11.6.255","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physiologyonline.1996.11.6.255","pdf_url":null,"source":{"id":"https://openalex.org/S88977973","display_name":"Physiology","issn_l":"0886-1714","issn":["0886-1714","1522-161X","1548-9213","1548-9221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057850926","display_name":"J. E. Hall","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JE Hall","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111765926","display_name":"D. H. Zappe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"DH Zappe","raw_affiliation_strings":["","Astra Merck"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]},{"raw_affiliation_string":"Astra Merck","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011841622","display_name":"Magdalena Alonso\u2010Galicia","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Alonso-Galicia","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074069269","display_name":"J. P. Granger","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JP Granger","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014696253","display_name":"M BRANDS","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MW Brands","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109246379","display_name":"SE Kassab","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"SE Kassab","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0469,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.88215294,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"11","issue":"6","first_page":"255","last_page":"261"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11001","display_name":"Renin-Angiotensin System Studies","score":0.03739999979734421,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12075","display_name":"Sodium Intake and Health","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8309999704360962},{"id":"https://openalex.org/keywords/essential-hypertension","display_name":"essential hypertension","score":0.9430000185966492},{"id":"https://openalex.org/keywords/renal-tubular-sodium-reabsorption","display_name":"tubular sodium reabsorption","score":0.9279999732971191},{"id":"https://openalex.org/keywords/pressure-natriuresis","display_name":"pressure natriuresis","score":0.8600000143051147},{"id":"https://openalex.org/keywords/sympathetic-activation","display_name":"sympathetic activation","score":0.8199999928474426},{"id":"https://openalex.org/keywords/renal-hypertension","display_name":"renal hypertension","score":0.3100000023841858}],"concepts":[{"id":"https://openalex.org/C2780512574","wikidata":"https://www.wikidata.org/wiki/Q2409399","display_name":"Renal medulla","level":3,"score":0.7222154140472412},{"id":"https://openalex.org/C174459258","wikidata":"https://www.wikidata.org/wiki/Q6980232","display_name":"Natriuresis","level":3,"score":0.7126270532608032},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6160544157028198},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6009366512298584},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5820609927177429},{"id":"https://openalex.org/C56906281","wikidata":"https://www.wikidata.org/wiki/Q4391435","display_name":"Reabsorption","level":3,"score":0.5819458961486816},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.5617954730987549},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.5564045310020447},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5285619497299194},{"id":"https://openalex.org/C2992149932","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Human obesity","level":3,"score":0.5263354182243347},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.523573100566864},{"id":"https://openalex.org/C57190642","wikidata":"https://www.wikidata.org/wiki/Q7144839","display_name":"Pathophysiology of hypertension","level":3,"score":0.44516465067863464},{"id":"https://openalex.org/C161457703","wikidata":"https://www.wikidata.org/wiki/Q3317402","display_name":"Renal physiology","level":3,"score":0.41947516798973083}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1152/physiologyonline.1996.11.6.255","doi":"https://doi.org/10.1152/physiologyonline.1996.11.6.255","is_oa":false,"landing_page_url":"https://doi.org/10.1152/physiologyonline.1996.11.6.255","pdf_url":null,"source":{"id":"https://openalex.org/S88977973","display_name":"Physiology","issn_l":"0886-1714","issn":["0886-1714","1522-161X","1548-9213","1548-9221"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Physiology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4255827560","https://openalex.org/W2054310260","https://openalex.org/W2034487535","https://openalex.org/W2151009383","https://openalex.org/W2077179567","https://openalex.org/W2119269572","https://openalex.org/W1489213547","https://openalex.org/W2104526328","https://openalex.org/W2049525976","https://openalex.org/W2024401715"],"abstract_inverted_index":{"Obesity":[0],"is":[1],"a":[2],"major":[3],"cause":[4],"of":[5,38],"human":[6],"essential":[7],"hypertension.":[8,25],"Recent":[9],"studies":[10],"point":[11],"toward":[12],"increased":[13],"renal":[14,19,30,50],"tubular":[15],"reabsorption":[16],"and":[17,43],"abnormal":[18],"pressure":[20],"natriuresis":[21],"in":[22],"mediating":[23],"obesity":[24],"The":[26],"mechanisms":[27],"for":[28],"these":[29],"changes":[31],"appear":[32],"to":[33],"be":[34],"multifactorial,":[35],"including":[36],"activation":[37],"the":[39,49],"sympathetic":[40],"nervous":[41],"system":[42],"altered":[44],"intrarenal":[45],"histology,":[46],"which":[47],"compresses":[48],"medulla.":[51]},"counts_by_year":[{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}