{"id":"https://openalex.org/W2158317072","doi":"https://doi.org/10.1110/ps.04781504","title":"Optimal bundling of transmembrane helices using sparse distance constraints","display_name":"Optimal bundling of transmembrane helices using sparse distance constraints","publication_year":2004,"publication_date":"2004-09-01","ids":{"openalex":"https://openalex.org/W2158317072","doi":"https://doi.org/10.1110/ps.04781504","mag":"2158317072","pmid":"https://pubmed.ncbi.nlm.nih.gov/15340162","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2286557"},"language":"en","primary_location":{"id":"doi:10.1110/ps.04781504","doi":"https://doi.org/10.1110/ps.04781504","is_oa":true,"landing_page_url":"https://doi.org/10.1110/ps.04781504","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1110/ps.04781504","source":{"id":"https://openalex.org/S156919612","display_name":"Protein Science","issn_l":"0961-8368","issn":["0961-8368","1469-896X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Protein Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1110/ps.04781504","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045170268","display_name":"Ken Sale","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I192454743","display_name":"Sandia National Laboratories California","ror":"https://ror.org/058m7ey48","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I192454743","https://openalex.org/I198811213","https://openalex.org/I4210104735"]},{"id":"https://openalex.org/I4210104735","display_name":"Sandia National Laboratories","ror":"https://ror.org/01apwpt12","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I198811213","https://openalex.org/I4210104735"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ken Sale","raw_affiliation_strings":["Biosystems Research Department, Sandia National Laboratories, P.O. Box 969, MS 9951, Livermore CA 94551-0969, USA. klsale@sandia.gov","Sandia National Laboratories, Livermore, California 94551-0969, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biosystems Research Department, Sandia National Laboratories, P.O. Box 969, MS 9951, Livermore CA 94551-0969, USA. klsale@sandia.gov","institution_ids":["https://openalex.org/I192454743","https://openalex.org/I4210104735"]},{"raw_affiliation_string":"Sandia National Laboratories, Livermore, California 94551-0969, USA","institution_ids":["https://openalex.org/I192454743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052158750","display_name":"Jean\u2010Loup Faulon","orcid":"https://orcid.org/0000-0003-4274-2953","observed_orcids":["https://orcid.org/0000-0003-4274-2953"]},"institutions":[{"id":"https://openalex.org/I192454743","display_name":"Sandia National Laboratories California","ror":"https://ror.org/058m7ey48","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I192454743","https://openalex.org/I198811213","https://openalex.org/I4210104735"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean\u2010Loup Faulon","raw_affiliation_strings":["Sandia National Laboratories, Livermore, California 94551-0969, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sandia National Laboratories, Livermore, California 94551-0969, USA","institution_ids":["https://openalex.org/I192454743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019502500","display_name":"Genetha A. Gray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I192454743","display_name":"Sandia National Laboratories California","ror":"https://ror.org/058m7ey48","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I192454743","https://openalex.org/I198811213","https://openalex.org/I4210104735"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Genetha A. Gray","raw_affiliation_strings":["Sandia National Laboratories, Livermore, California 94551-0969, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sandia National Laboratories, Livermore, California 94551-0969, USA","institution_ids":["https://openalex.org/I192454743"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069555858","display_name":"Joseph S. Schoeniger","orcid":"https://orcid.org/0000-0002-2719-7435","observed_orcids":["https://orcid.org/0000-0002-2719-7435"]},"institutions":[{"id":"https://openalex.org/I192454743","display_name":"Sandia National Laboratories California","ror":"https://ror.org/058m7ey48","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I192454743","https://openalex.org/I198811213","https://openalex.org/I4210104735"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph S. Schoeniger","raw_affiliation_strings":["Sandia National Laboratories, Livermore, California 94551-0969, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sandia National Laboratories, Livermore, California 94551-0969, USA","institution_ids":["https://openalex.org/I192454743"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068729397","display_name":"Malin M. Young","orcid":"https://orcid.org/0000-0001-8343-4469","observed_orcids":["https://orcid.org/0000-0001-8343-4469"]},"institutions":[{"id":"https://openalex.org/I192454743","display_name":"Sandia National Laboratories California","ror":"https://ror.org/058m7ey48","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I192454743","https://openalex.org/I198811213","https://openalex.org/I4210104735"]},{"id":"https://openalex.org/I4210104735","display_name":"Sandia National Laboratories","ror":"https://ror.org/01apwpt12","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I198811213","https://openalex.org/I4210104735"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Malin M. Young","raw_affiliation_strings":["Biosystems Research Department, Sandia National Laboratories, P.O. Box 969, MS 9951, Livermore CA 94551-0969, USA; fax: (925) 294-3020","Sandia National Laboratories, Livermore, California 94551-0969, USA","Biosystems Research Department, Sandia National Laboratories, P.O. Box 969, MS 9951, Livermore CA 94551-0969, USA","fax: (925) 294-3020"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biosystems Research Department, Sandia National Laboratories, P.O. Box 969, MS 9951, Livermore CA 94551-0969, USA; fax: (925) 294-3020","institution_ids":["https://openalex.org/I192454743","https://openalex.org/I4210104735"]},{"raw_affiliation_string":"Sandia National Laboratories, Livermore, California 94551-0969, USA","institution_ids":["https://openalex.org/I192454743"]},{"raw_affiliation_string":"Biosystems Research Department, Sandia National Laboratories, P.O. Box 969, MS 9951, Livermore CA 94551-0969, USA","institution_ids":["https://openalex.org/I192454743","https://openalex.org/I4210104735"]},{"raw_affiliation_string":"fax: (925) 294-3020","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5068729397"],"corresponding_institution_ids":["https://openalex.org/I192454743","https://openalex.org/I4210104735"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":1.7568,"has_fulltext":true,"cited_by_count":43,"citation_normalized_percentile":{"value":0.83768783,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"13","issue":"10","first_page":"2613","last_page":"2627"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/integral-membrane-proteins","display_name":"integral membrane proteins","score":0.9120000004768372},{"id":"https://openalex.org/keywords/cross-linking","display_name":"crosslinking","score":0.8149999976158142},{"id":"https://openalex.org/keywords/fluorescence-resonance-energy-transfer","display_name":"fluorescence resonance energy transfer","score":0.9940000176429749},{"id":"https://openalex.org/keywords/conformational-search","display_name":"conformational search","score":0.7519999742507935},{"id":"https://openalex.org/keywords/structure-refinement","display_name":"structure refinement","score":0.5419999957084656},{"id":"https://openalex.org/keywords/penalty-function","display_name":"penalty method","score":0.9620000123977661},{"id":"https://openalex.org/keywords/protein-structure-determination","display_name":"protein structure determination","score":0.4779999852180481}],"concepts":[{"id":"https://openalex.org/C2778134712","wikidata":"https://www.wikidata.org/wiki/Q1047307","display_name":"Bundle","level":2,"score":0.49216359853744507},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.4865071177482605},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.42669856548309326},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.41982728242874146},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4176216721534729},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.4163486361503601},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.39551079273223877},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.3414829969406128},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.32201087474823},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.31802496314048767},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31755751371383667},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.14723289012908936},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08146870136260986},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012243","descriptor_name":"Rhodopsin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017433","descriptor_name":"Protein Structure, Secondary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017434","descriptor_name":"Protein Structure, Tertiary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1110/ps.04781504","doi":"https://doi.org/10.1110/ps.04781504","is_oa":true,"landing_page_url":"https://doi.org/10.1110/ps.04781504","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1110/ps.04781504","source":{"id":"https://openalex.org/S156919612","display_name":"Protein Science","issn_l":"0961-8368","issn":["0961-8368","1469-896X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Protein Science","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2286557","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2286557","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Protein Sci","raw_type":"Text"},{"id":"pmid:15340162","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15340162","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Protein science : a publication of the Protein Society","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/2d72c08a-fd27-4ff6-85e5-cea74969819d","doi":null,"is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/2d72c08a-fd27-4ff6-85e5-cea74969819d","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sale, K, Faulon, J-L, Gray, G A, Schoeniger, J S & Young, M M 2004, 'Optimal bundling of transmembrane helices using sparse distance constraints.', Protein science : a publication of the Protein Society, vol. 13, no. 10. https://doi.org/10.1110/ps.04781504","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-05779676v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-05779676","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Protein Science, 2004, 13 (10), ⟨10.1110/ps.04781504⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1110/ps.04781504","doi":"https://doi.org/10.1110/ps.04781504","is_oa":true,"landing_page_url":"https://doi.org/10.1110/ps.04781504","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1110/ps.04781504","source":{"id":"https://openalex.org/S156919612","display_name":"Protein Science","issn_l":"0961-8368","issn":["0961-8368","1469-896X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Protein Science","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G194215011","display_name":null,"funder_award_id":"DE\u2013AC04\u201394AL85000","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"},{"id":"https://openalex.org/G2075401295","display_name":null,"funder_award_id":"DE-AC04- 94AL85000","funder_id":"https://openalex.org/F4320332369","funder_display_name":"National Nuclear Security Administration"},{"id":"https://openalex.org/G351415096","display_name":null,"funder_award_id":"DEAC04-94AL85000","funder_id":"https://openalex.org/F4320338291","funder_display_name":"Sandia National Laboratories"},{"id":"https://openalex.org/G7318852158","display_name":null,"funder_award_id":"AC04-94AL85000","funder_id":"https://openalex.org/F4320338291","funder_display_name":"Sandia National Laboratories"},{"id":"https://openalex.org/G8456466421","display_name":null,"funder_award_id":"AC04-94AL85000","funder_id":"https://openalex.org/F4320306084","funder_display_name":"U.S. Department of Energy"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320332369","display_name":"National Nuclear Security Administration","ror":"https://ror.org/03sk1we31"},{"id":"https://openalex.org/F4320338291","display_name":"Sandia National Laboratories","ror":"https://ror.org/01apwpt12"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2158317072.pdf","grobid_xml":"https://content.openalex.org/works/W2158317072.grobid-xml"},"referenced_works_count":80,"referenced_works":["https://openalex.org/W33729716","https://openalex.org/W109881820","https://openalex.org/W1522271501","https://openalex.org/W1544988812","https://openalex.org/W1736189198","https://openalex.org/W1963581387","https://openalex.org/W1963687863","https://openalex.org/W1965549841","https://openalex.org/W1970621515","https://openalex.org/W1974843618","https://openalex.org/W1977087490","https://openalex.org/W1985219728","https://openalex.org/W1993347252","https://openalex.org/W1994019984","https://openalex.org/W1995017064","https://openalex.org/W1995050941","https://openalex.org/W1996266656","https://openalex.org/W1996477048","https://openalex.org/W1997156132","https://openalex.org/W2000729091","https://openalex.org/W2001020509","https://openalex.org/W2001662753","https://openalex.org/W2004525617","https://openalex.org/W2006555292","https://openalex.org/W2008954354","https://openalex.org/W2012387523","https://openalex.org/W2012534919","https://openalex.org/W2013701986","https://openalex.org/W2019742616","https://openalex.org/W2020568706","https://openalex.org/W2024060531","https://openalex.org/W2026907061","https://openalex.org/W2027354448","https://openalex.org/W2027711565","https://openalex.org/W2029318495","https://openalex.org/W2029667189","https://openalex.org/W2029837084","https://openalex.org/W2035459350","https://openalex.org/W2039134432","https://openalex.org/W2043023293","https://openalex.org/W2049359390","https://openalex.org/W2051052308","https://openalex.org/W2052236563","https://openalex.org/W2053960813","https://openalex.org/W2055672066","https://openalex.org/W2056514923","https://openalex.org/W2056760934","https://openalex.org/W2062351773","https://openalex.org/W2063249275","https://openalex.org/W2067106661","https://openalex.org/W2068077460","https://openalex.org/W2068739756","https://openalex.org/W2069865904","https://openalex.org/W2071155271","https://openalex.org/W2073035613","https://openalex.org/W2074182813","https://openalex.org/W2074243206","https://openalex.org/W2074266029","https://openalex.org/W2076394025","https://openalex.org/W2076921684","https://openalex.org/W2080301705","https://openalex.org/W2083637735","https://openalex.org/W2101522386","https://openalex.org/W2102557954","https://openalex.org/W2103993180","https://openalex.org/W2117385186","https://openalex.org/W2125572210","https://openalex.org/W2125579011","https://openalex.org/W2133131542","https://openalex.org/W2142385137","https://openalex.org/W2144112248","https://openalex.org/W2149963584","https://openalex.org/W2155147384","https://openalex.org/W2155694817","https://openalex.org/W2157241719","https://openalex.org/W2160743730","https://openalex.org/W2161255664","https://openalex.org/W2407615930","https://openalex.org/W4233439880","https://openalex.org/W7074179453"],"related_works":["https://openalex.org/W2115387049","https://openalex.org/W2586166577","https://openalex.org/W2035459350","https://openalex.org/W2048104038","https://openalex.org/W2789906771","https://openalex.org/W2073609795","https://openalex.org/W2046772252","https://openalex.org/W2054765448","https://openalex.org/W2912454892","https://openalex.org/W2170670602"],"abstract_inverted_index":{"We":[0,94,118],"present":[1],"a":[2,49,71,126,159],"two-step":[3],"approach":[4],"to":[5,56,144,182],"modeling":[6],"the":[7,41,98,102,109,113,121,145,154,168,177,187],"transmembrane":[8],"spanning":[9],"helical":[10,139],"bundles":[11,140],"of":[12,44,51,83,101,112,128,137,161,179,186],"integral":[13],"membrane":[14,45,85,104],"proteins":[15],"using":[16,36,125,158],"only":[17,162],"sparse":[18],"distance":[19,52,89,164],"constraints,":[20],"such":[21],"as":[22],"those":[23,149],"derived":[24,79],"from":[25,80,92,107,148,153,167],"chemical":[26],"cross-linking,":[27],"dipolar":[28],"EPR":[29],"and":[30,88],"FRET":[31],"experiments.":[32,93],"In":[33,64],"Step":[34,65],"1,":[35],"an":[37],"algorithm,":[38],"we":[39,170],"developed,":[40],"conformational":[42,62],"space":[43],"protein":[46,86,105],"folds":[47],"matching":[48],"set":[50,127,160],"constraints":[53,90,165],"is":[54,135],"explored":[55],"provide":[57],"initial":[58],"structures":[59,68,87,106],"for":[60],"local":[61],"searches.":[63],"2,":[66],"these":[67],"refined":[69],"against":[70],"custom":[72],"penalty":[73,114,122],"function":[74,115],"that":[75,133,141,150,172],"incorporates":[76],"both":[77],"measures":[78],"statistical":[81,99],"analysis":[82,100],"solved":[84,103],"obtained":[91],"begin":[95],"by":[96],"describing":[97],"which":[108],"theoretical":[110],"portion":[111],"was":[116],"derived.":[117],"then":[119],"describe":[120],"function,":[123],"and,":[124],"six":[129],"test":[130],"cases,":[131],"demonstrate":[132],"it":[134],"capable":[136],"distinguishing":[138],"are":[142,151],"close":[143],"native":[146,155],"bundle":[147],"far":[152],"bundle.":[156],"Finally,":[157],"27":[163],"extracted":[166],"literature,":[169],"show":[171],"our":[173],"method":[174],"successfully":[175],"recovers":[176],"structure":[178],"dark-adapted":[180],"rhodopsin":[181],"within":[183],"3.2":[184],"A":[185],"crystal":[188],"structure.":[189]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}