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3663,3680,3711,3775,3789,3890,3906,3946,3949,3965,4015,4057,4126,4154,4230,4317,4374,4467,4616,4649,4705,4736,4786,4928,4932,4986,5012,5054,5061,5063,5092,5118,5137,5171,5289,5307,5322,5339,5403,5410,5418,5502,5534],"CVD":[7,34,55,120,162,393,408,456,526,759,1139,1151,1290,1308,1353,1461,1606,1655,1668,1714,1743,1758,1793,2034,2763,2800,3291,3299,3382,3401,3421,3466,3562,3648,3689,3726,3743,3804,3868,4242,4288,4521,4536,4593,4728,4948,4987,5213,5391,5404],"A.":[8,35,63],"Type":[9,60,76,3778],"2":[10,61,77,400,509,531,584,613,676,689,789,985,1144,1202,1213,1250,1675,1773,1883,1936,1963,3653,3701,3719,3753,3779,4040,4134,4211,4348,4413,4495,4541,4573,4598,4734,4752,5043,5081,5199,5275,5330],"diabetes":[11,401,471,485,510,677,690,790,1676,1686,1730,1884,3185,3537,3567,3654,3702,3720,3754,4041,4496,4542,4574,4599,4735,4753,4985,5082,5200],"B.":[12,40,66],"Elevated":[13,2268],"glucose":[14,201,245,284,326,331,351,354,556,700,737,854,876,893,940,980,1065,1101,1173,1221,1226,1240,1301,1535,1553,1580,1610,1638,1815,1864,1900,1973,2001,2172,2186,2219,2263,2270,2277,2282,2322,2390,2440,2505,2731,2995,3374,3475,3993,4055,4150,4377,4385,4785,4837,4868,5094,5254,5433],"concentrations":[15,2323,3476,3994,5434],"in":[16,22,92,105,155,166,177,229,238,275,337,359,409,418,431,437,448,472,527,569,578,591,596,606,611,632,647,668,710,729,812,821,863,931,983,994,1020,1043,1140,1157,1160,1262,1266,1291,1296,1309,1316,1354,1358,1374,1376,1393,1396,1446,1471,1516,1541,1575,1593,1640,1657,1687,1715,1721,1759,1766,1800,1804,1808,1826,1858,1979,1994,2022,2181,2192,2233,2306,2343,2369,2500,2510,2558,2577,2598,2604,2622,2653,2662,2738,2745,2796,2945,3119,3143,3187,3196,3217,3266,3292,3316,3330,3347,3366,3386,3395,3522,3534,3564,3569,3649,3690,3697,3715,3742,3777,3815,3841,3879,3902,3913,3944,3961,4007,4035,4069,4079,4113,4128,4245,4287,4292,4315,4404,4411,4447,4474,4491,4505,4522,4537,4544,4558,4575,4583,4594,4601,4622,4665,4729,4737,4748,4782,4834,4848,4865,4949,4988,5027,5069,5083,5107,5217,5222,5248,5256,5302,5361,5379,5513,5535],"the":[17,106,141,156,167,204,218,224,319,338,360,366,379,390,419,422,460,468,481,488,497,505,523,535,625,662,711,756,775,798,824,840,864,914,934,948,977,1005,1023,1062,1096,1136,1163,1231,1257,1287,1321,1339,1389,1414,1438,1458,1517,1522,1542,1603,1626,1635,1641,1652,1658,1665,1682,1697,1709,1742,1749,1755,1785,1790,1801,1827,1830,1833,1843,1846,1849,1855,1953,1959,1995,2044,2055,2150,2209,2223,2252,2287,2328,2344,2365,2387,2425,2449,2461,2483,2490,2518,2523,2581,2633,2656,2714,2769,2781,2797,2803,2877,2914,2937,2965,3020,3092,3149,3177,3197,3205,3240,3259,3279,3325,3339,3348,3416,3432,3447,3452,3456,3463,3499,3510,3523,3559,3579,3584,3610,3630,3660,3675,3686,3732,3767,3794,3809,3839,3852,3874,3903,3914,3930,3939,3971,3997,4017,4032,4036,4043,4070,4094,4102,4106,4114,4119,4142,4165,4174,4188,4202,4215,4227,4232,4246,4255,4269,4274,4293,4304,4309,4325,4333,4344,4355,4419,4430,4436,4485,4488,4508,4517,4523,4559,4584,4590,4609,4614,4619,4627,4666,4674,4678,4687,4699,4725,4802,4805,4824,4862,4874,4877,4893,4945,4959,4970,4976,4982,5007,5025,5039,5050,5070,5108,5153,5161,5169,5181,5257,5269,5350,5357,5362,5398,5448,5465,5470,5483,5491,5497,5508,5514,5528],"nondiabetic":[18,107,361,412,441,817,1600,1642,1716,1809,1859,1889,1980,3296,3367],"range":[19,1643,5258],"C.":[20,44,68],"Atherosclerosis":[21,2084],"subjects":[23,262,572,581,599,615,819,987,1045,1161,1181,1207,1310,1329,1355,1549,1722,1761,1768,1810,1860,1875,1890,1981,2806,2823,3368,3539,3570,3962,4131,4405,4545,4576,4602,4632,4738,4765,5084,5103,5223,5249,5538],"with":[24,51,94,116,329,398,411,440,529,602,622,674,687,706,763,785,816,953,981,1142,1162,1193,1208,1216,1293,1299,1311,1330,1336,1356,1380,1383,1385,1403,1407,1531,1550,1609,1647,1701,1811,1861,1881,1891,1898,1910,1929,1961,2121,2320,2464,2562,2768,2807,2824,2855,2881,2908,2947,3030,3035,3146,3183,3298,3306,3390,3397,3420,3425,3536,3540,3566,3571,3651,3692,3699,3717,3751,3836,3963,4025,4132,4209,4235,4392,4406,4493,4539,4546,4577,4596,4603,4645,4653,4698,4732,4739,4750,4766,4790,4799,4844,4990,5085,5205,5224,5250,5310,5349,5451,5464,5532,5539],"asymptomatic":[25,1955],"hyperglycemia":[26,39,182,231,373,388,521,765,769,1134,1149,1481,1493,1712,1788,1893,1956,2032,2065,2137,2244,2255,2414,2750,2782,2923,2955,2963,2988,3018,3362,3419,3445,3461,3479,3521,4747,4923,5037,5348,5372,5383,5402,5437,5463,5512],"III.":[27],"Causal":[28],"Relationship":[29],"of":[30,38,88,111,119,122,131,186,206,220,223,267,295,318,341,348,381,392,406,421,455,462,467,470,483,490,499,507,514,525,539,553,620,653,713,758,806,826,828,907,916,918,923,936,938,947,969,979,990,998,1014,1027,1041,1064,1122,1138,1200,1289,1307,1328,1338,1352,1391,1416,1433,1441,1450,1460,1475,1484,1487,1496,1500,1502,1524,1560,1596,1605,1612,1654,1667,1673,1684,1692,1699,1741,1751,1757,1792,1798,1829,1832,1837,1848,1854,1902,1943,2088,2113,2141,2152,2169,2197,2205,2211,2225,2243,2254,2276,2300,2311,2330,2335,2346,2351,2361,2375,2389,2396,2427,2435,2439,2448,2460,2470,2475,2485,2515,2526,2570,2590,2602,2611,2616,2635,2655,2670,2674,2700,2707,2711,2716,2730,2757,2762,2771,2793,2799,2835,2842,2844,2869,2916,2936,2967,2992,3017,3022,3058,3091,3127,3138,3152,3173,3180,3202,3220,3228,3242,3261,3295,3320,3341,3350,3361,3418,3434,3454,3465,3473,3501,3519,3525,3548,3561,3581,3587,3635,3644,3677,3688,3749,3766,3803,3855,3876,3941,3970,3973,3984,3999,4020,4038,4082,4105,4121,4144,4167,4190,4201,4217,4241,4257,4273,4311,4327,4336,4346,4361,4363,4372,4383,4397,4421,4438,4442,4451,4461,4469,4487,4510,4520,4533,4571,4586,4592,4611,4626,4629,4668,4681,4703,4708,4727,4804,4827,4873,4876,4896,4947,4962,4978,4984,5009,5142,5156,5163,5168,5183,5191,5210,5220,5259,5265,5271,5282,5352,5356,5428,5431,5443,5447,5457,5467,5472,5485,5499,5510,5516,5520,5530,5546],"Postprandial":[31],"to":[33,74,113,124,212,261,324,385,487,727,753,797,887,913,933,1054,1082,1170,1180,1188,1190,1211,1247,1468,1528,1570,1585,1681,1724,1748,1823,1992,2038,2075,2149,2183,2194,2208,2249,2266,2273,2309,2317,2340,2401,2419,2482,2489,2502,2512,2529,2609,2631,2691,2702,2719,2743,2786,2875,2889,2919,2934,2994,3002,3161,3215,3238,3244,3263,3336,3357,3372,3451,3483,3498,3605,3621,3756,3924,4004,4010,4027,4061,4100,4163,4300,4516,4550,4588,4651,4659,4689,4723,4814,4860,4904,4915,4943,4998,5002,5076,5122,5147,5152,5196,5237,5273,5314,5328,5368,5460],"Direct":[36],"effects":[37,2087,2168,2178,2462,2492,3472,3854,3866,4120,4189,4256,4437,4450,4486,5209,5430],"Insufficient":[41,2883],"insulin":[42,1112,2082,2094,2739,2777,2884,2905,2909,2928,2949,2974,3004,3108,3164,3174,3253,3270,3321,3345,3364,3405,3489,3645,3672,3713,3761,3791,3833,3856,3888,3904,3987,4049,4127,4160,4787,4926,5057,5059,5290,5336,5415],"production":[43,2778,2885,2950,3084],"Insulin":[45,64,3210,3955,4169,4792],"resistance":[46,2095,2910,2929,3346],"hyperinsulinemia":[48,2097,3069,3283,3343,3380,4021],"D.":[49,70],"Association":[50,4307],"risk":[52,118,127,147,188,219,234,303,391,405,454,489,502,712,723,757,858,903,906,992,1017,1059,1073,1199,1459,1511,1523,1604,1653,1666,1744,1756,2123,2814,2858,3037,3288,3308,3398,3464,3547,3560,3676,3687,3802,3818,3940,3972,3998,4454,4591,4909,4946,5388,5420,5471,5545],"factors":[53,148,304,479,503,1060,1074,2124,2815,2859,3038,3399,3428,3819,4455,4910,5421],"for":[54,59,100,149,236,305,368,628,665,692,809,860,1056,1100,1111,1275,1401,1426,1513,1784,1920,1925,2014,2027,2054,2101,2125,2166,2258,2386,2755,2791,2913,3039,3290,3400,3469,3514,3530,3727,3832,4308,4343,4456,4529,4720,4764,4823,4839,4911,5015,5319,5326,5390,5397,5422,5425,5507,5527,5537],"IV.":[56],"Therapeutic":[57,383],"Interventions":[58],"Diabetes":[62,78,776,949,3661,3735,3780,4312,4560,5228],"therapy":[65,3646,3673,3714,3729,3834,3857,3956,4275,4388],"Sulfonylureas":[67,4029],"Biguanides":[69],"Acarbose":[71,4655,4741,4899],"V.":[72],"Studies":[73,1268],"Prevent":[75],"VI.":[79],"Conclusions":[80],"CARDIOVASCULAR":[81],"disease":[82,563,609,716,1068,1565,3679,3893],"(CVD)":[83],"is":[84,97,183,194,232,272,291,312,315,322,334,457,465,493,760,988,1011,1069,1167,1508,1669,1678,1718,2138,2145,2163,2239,2247,2283,2302,2522,2732,2819,2838,2873,2886,2959,2971,3028,3284,3327,3352,3355,3412,3446,3480,3602,3655,3849,3966,4199,4252,4298,4365,4389,4429,4434,4580,4742,4871,4969,4974,5024,5144,5232,5268,5295,5343,5359,5438],"a":[85,117,195,233,250,292,369,428,434,518,544,551,603,618,629,648,669,707,772,857,996,1128,1196,1359,1371,1427,1454,1509,1594,1970,2028,2067,2107,2111,2139,2230,2337,2705,2753,2788,2840,2892,2952,3014,3110,3181,3192,3226,3286,3317,3423,3682,3722,3745,3798,3877,3884,4181,4221,4283,4501,4530,4564,4646,4662,4770,4778,4816,4831,4845,5016,5074,5234,5251,5296,5375,5386,5406,5426,5440],"major":[86,663,3448],"cause":[87,2112,2990,3216,5442],"morbidity":[89,102,720],"mortality":[91,104,559,595,610,667,718,928,1566],"patients":[93,528,621,673,686,730,784,810,1141,1806,1880,3297,3535,3565,3650,3691,3698,3716,3750,4208,4492,4538,4595,4731,4749,4840,4849,4989,5001,5014,5531],"diabetes.":[95,532,1145,1191,1251,1753,1964,4135,4168,4212,4414,4993],"It":[96,333,2199,2895,2958,3411,3848,4399],"also":[98,395,494,902,911,1153,1279,1347,2303,2416,2628,2651,2688,2724,2853,2960,3211,3254,3544,3782,3950,4253,4757,4795,4901,4920,5468],"responsible":[99,2100,2912],"significant":[101,545,1455,1948,3785,4285,4503],"population.":[108],"The":[109,453,512,722,793,905,967,1076,1120,1146,1435,1465,1498,1888,1984,2280,2373,2453,2760,2833,3105,3642,3763,3895,3982,4194,4250,4359,4440,4809,4821,5020,5067,5097,5127,5140,5208,5226,5262,5292,5518],"development":[110,205,380,482,524,1137,1432,1791,2151,2210,2345,2484,2761,2798,2915,3021,3349,3453,3500,3524,4667,4726,4983,5351,5515],"strategies":[112,384,3555],"recognize":[114],"individuals":[115,1292,1379,1395],"interventions":[123,211,5187,5459,5501],"reduce":[125,217,386,3991,4052,4062,4589,4944,5461],"this":[126,178,813,1276,1397,1775,2023,2135,2717,2920,4262,4337,4443,4511,4715,4828,4880,5266],"would":[128,2943,3000,3921],"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