{"id":"https://openalex.org/W2157686456","doi":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","title":"The Impact of Parity and Duration of Biotin Supplementation on White Line Disease Lameness in Dairy Cattle","display_name":"The Impact of Parity and Duration of Biotin Supplementation on White Line Disease Lameness in Dairy Cattle","publication_year":2003,"publication_date":"2003-08-01","ids":{"openalex":"https://openalex.org/W2157686456","doi":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","mag":"2157686456","pmid":"https://pubmed.ncbi.nlm.nih.gov/12939081"},"language":"en","primary_location":{"id":"doi:10.3168/jds.s0022-0302(03)73852-1","doi":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","pdf_url":"http://www.journalofdairyscience.org/article/S0022030203738521/pdf","source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.journalofdairyscience.org/article/S0022030203738521/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075249796","display_name":"Carsten Jochen P\u00f6tzsch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C.J. P\u00f6tzsch","raw_affiliation_strings":["Ecology and Epidemiology Group, Department of Biological Sciences, University of Warwick, Coventry, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ecology and Epidemiology Group, Department of Biological Sciences, University of Warwick, Coventry, UK","institution_ids":["https://openalex.org/I39555362"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082110589","display_name":"V.J. Collis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22090551","display_name":"Agricultural Development Advisory Service (United Kingdom)","ror":"https://ror.org/006d11e04","country_code":"GB","type":"company","lineage":["https://openalex.org/I22090551"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"V.J. Collis (n\u00e9e Hedges)","raw_affiliation_strings":["ADAS, Rosemaund, Preston Wynne, Hereford HR1 3PG, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ADAS, Rosemaund, Preston Wynne, Hereford HR1 3PG, UK","institution_ids":["https://openalex.org/I22090551"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113692259","display_name":"Roger W. Blowey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R.W. Blowey","raw_affiliation_strings":["Wood Veterinary Group, St. Oswalds Road, Gloucester, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wood Veterinary Group, St. Oswalds Road, Gloucester, UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054912412","display_name":"A.J. Packington","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A.J. Packington","raw_affiliation_strings":["Roche Vitamins (UK) Ltd., Heanor Gate, Heanor, Derbyshire, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Roche Vitamins (UK) Ltd., Heanor Gate, Heanor, Derbyshire, UK","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082790535","display_name":"Laura Elizabeth Green","orcid":"https://orcid.org/0000-0003-2957-8773","observed_orcids":["https://orcid.org/0000-0003-2957-8773"]},"institutions":[{"id":"https://openalex.org/I39555362","display_name":"University of Warwick","ror":"https://ror.org/01a77tt86","country_code":"GB","type":"education","lineage":["https://openalex.org/I39555362"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"L.E. Green","raw_affiliation_strings":["Ecology and Epidemiology Group, Department of Biological Sciences, University of Warwick, Coventry, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ecology and Epidemiology Group, Department of Biological Sciences, University of Warwick, Coventry, UK","institution_ids":["https://openalex.org/I39555362"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5082790535"],"corresponding_institution_ids":["https://openalex.org/I39555362"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":3.755,"has_fulltext":true,"cited_by_count":39,"citation_normalized_percentile":{"value":0.91857745,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"86","issue":"8","first_page":"2577","last_page":"2582"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10838","display_name":"Animal Behavior and Welfare Studies","score":0.7529000043869019,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10838","display_name":"Animal Behavior and Welfare Studies","score":0.7529000043869019,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10872","display_name":"Veterinary Equine Medical Research","score":0.08609999716281891,"subfield":{"id":"https://openalex.org/subfields/3402","display_name":"Equine"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10584","display_name":"Reproductive Physiology in Livestock","score":0.018699999898672104,"subfield":{"id":"https://openalex.org/subfields/1102","display_name":"Agronomy and Crop Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/white-line-disease","display_name":"white line disease","score":0.9100000262260437},{"id":"https://openalex.org/keywords/lameness","display_name":"lameness","score":0.972000002861023},{"id":"https://openalex.org/keywords/biotin-supplementation","display_name":"biotin supplementation","score":0.8820000290870667},{"id":"https://openalex.org/keywords/dairy-cows","display_name":"dairy cattle","score":0.8080000281333923},{"id":"https://openalex.org/keywords/parity","display_name":"parity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/multiparous-cows","display_name":"multiparous cows","score":0.7239999771118164},{"id":"https://openalex.org/keywords/primiparous-cows","display_name":"primiparous cows","score":0.9760000109672546},{"id":"https://openalex.org/keywords/supplementation-duration","display_name":"duration of supplementation","score":0.7639999985694885},{"id":"https://openalex.org/keywords/hoof-health","display_name":"hoof health","score":0.7279999852180481},{"id":"https://openalex.org/keywords/animal-welfare","display_name":"animal welfare","score":0.6710000038146973},{"id":"https://openalex.org/keywords/farm-economics","display_name":"farm economics","score":0.8100000023841858}],"concepts":[{"id":"https://openalex.org/C2779771469","wikidata":"https://www.wikidata.org/wiki/Q1428918","display_name":"Lameness","level":2,"score":0.9660441875457764},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6142604351043701},{"id":"https://openalex.org/C2776977481","wikidata":"https://www.wikidata.org/wiki/Q2915","display_name":"Dairy cattle","level":2,"score":0.5683652758598328},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.5410100817680359},{"id":"https://openalex.org/C194775826","wikidata":"https://www.wikidata.org/wiki/Q209542","display_name":"Herd","level":2,"score":0.4789848327636719},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.44913119077682495},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3120388686656952},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1405976116657257}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001710","descriptor_name":"Biotin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002418","descriptor_name":"Cattle Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002418","descriptor_name":"Cattle Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005534","descriptor_name":"Foot Diseases","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005534","descriptor_name":"Foot Diseases","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D005534","descriptor_name":"Foot Diseases","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D006724","descriptor_name":"Hoof and Claw","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007794","descriptor_name":"Lameness, Animal","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D007794","descriptor_name":"Lameness, Animal","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D010298","descriptor_name":"Parity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3168/jds.s0022-0302(03)73852-1","doi":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","pdf_url":"http://www.journalofdairyscience.org/article/S0022030203738521/pdf","source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},{"id":"pmid:12939081","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12939081","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of dairy science","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/186234c7-73a2-4c6c-8022-93bdec0a2ea0","doi":null,"is_oa":true,"landing_page_url":"https://research.birmingham.ac.uk/en/publications/186234c7-73a2-4c6c-8022-93bdec0a2ea0","pdf_url":null,"source":{"id":"https://openalex.org/S4306402634","display_name":"University of Birmingham Research Portal (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"P\u00f6tzsch, C J, Collis, V J, Blowey, R W, Packington, A J & Green, L E 2003, 'The impact of parity and duration of biotin supplementation on white line disease lameness in dairy cattle', Journal of Dairy Science, vol. 86, no. 8, pp. 2577-2582. https://doi.org/10.3168/jds.S0022-0302(03)73852-1","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3168/jds.s0022-0302(03)73852-1","doi":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.s0022-0302(03)73852-1","pdf_url":"http://www.journalofdairyscience.org/article/S0022030203738521/pdf","source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.958299994468689}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2157686456.pdf","grobid_xml":"https://content.openalex.org/works/W2157686456.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W253167819","https://openalex.org/W1969320169","https://openalex.org/W2011499635","https://openalex.org/W2020769791","https://openalex.org/W2036342612","https://openalex.org/W2045960281","https://openalex.org/W2059450076","https://openalex.org/W2067770310","https://openalex.org/W2106115101","https://openalex.org/W2145653017","https://openalex.org/W2152161786","https://openalex.org/W2157426231","https://openalex.org/W2160571019","https://openalex.org/W2335039360","https://openalex.org/W2417718369","https://openalex.org/W2421884396","https://openalex.org/W2797935920","https://openalex.org/W2801865214"],"related_works":["https://openalex.org/W1969320169","https://openalex.org/W2036342612","https://openalex.org/W2801865214","https://openalex.org/W172729856","https://openalex.org/W1981362910","https://openalex.org/W2725396269","https://openalex.org/W4256464708","https://openalex.org/W2168591359","https://openalex.org/W7221367925","https://openalex.org/W2088351955"],"abstract_inverted_index":{"A":[0],"field":[1],"study":[2,25],"was":[3,160,184],"conducted":[4],"to":[5,14,56,104,117,144,186],"examine":[6],"effects":[7],"of":[8,19,29,60,64,79,90,154,174,179,191,199],"oral":[9,67],"biotin":[10,68,91,134,155,200],"supplementation":[11,65,92,156,177,201],"for":[12,124,171,208],"up":[13,116],"18":[15],"mo":[16,183],"on":[17,72],"risks":[18],"lameness":[20,137,168,193,204],"in":[21,36,40,53,101,111,126,140,157,166,194,202],"dairy":[22,34],"cows.":[23,196],"The":[24,46,197],"included":[26],"a":[27,41,176],"total":[28],"900":[30],"cattle":[31],"from":[32,48,93],"five":[33],"farms":[35],"Gloucestershire,":[37],"southwest":[38],"U.K.,":[39],"within-herd":[42],"randomized":[43],"control":[44],"trial.":[45],"data":[47,81],"this":[49,54],"trial":[50],"were":[51,169],"used":[52],"paper":[55],"investigate":[57],"the":[58,80,152,189],"impact":[59,207],"parity":[61,88],"and":[62,212],"duration":[63],"with":[66,86,133],"at":[69,180],"20":[70],"mg/d":[71],"white":[73],"line":[74],"disease":[75],"(WLD)":[76],"lameness.":[77],"Analysis":[78],"indicated":[82],"that":[83],"WLD":[84,136,167,192],"increased":[85],"increasing":[87],"independent":[89],"approximately":[94],"two":[95],"cases":[96,106,119,146],"per":[97,107,120,147],"100":[98,108,121,148],"cow":[99,109,122,149],"years":[100,110,123],"primiparous":[102,158],"cows":[103,125,142,159],"15.5":[105],"all":[112],"multiparous":[113,141,195],"cows,":[114],"but":[115],"47.7":[118],"parities":[127],">":[128],"or":[129],"=":[130],"5.":[131],"Supplementation":[132],"reduced":[135],"by":[138],"45%":[139],"down":[143],"8.5":[145],"years,":[150],"whereas":[151],"effect":[153,198],"not":[161],"significant.":[162],"Although":[163],"numerical":[164],"reductions":[165],"observed":[170],"shorter":[172],"periods":[173],"supplementation,":[175],"length":[178],"least":[181],"6":[182],"required":[185],"significantly":[187],"reduce":[188],"risk":[190],"reducing":[203],"has":[205],"potential":[206],"both":[209],"animal":[210],"welfare":[211],"farm":[213],"economics.":[214]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}