{"id":"https://openalex.org/W2157342744","doi":"https://doi.org/10.1016/j.bbmt.2008.02.006","title":"Transplantation in Remission Improves the Disease-Free Survival of Patients with Advanced Myelodysplastic Syndromes Treated with Myeloablative T Cell-Depleted Stem Cell Transplants from HLA-Identical Siblings","display_name":"Transplantation in Remission Improves the Disease-Free Survival of Patients with Advanced Myelodysplastic Syndromes Treated with Myeloablative T Cell-Depleted Stem Cell Transplants from HLA-Identical Siblings","publication_year":2008,"publication_date":"2008-03-14","ids":{"openalex":"https://openalex.org/W2157342744","doi":"https://doi.org/10.1016/j.bbmt.2008.02.006","mag":"2157342744","pmid":"https://pubmed.ncbi.nlm.nih.gov/18342789","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4498391"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbmt.2008.02.006","doi":"https://doi.org/10.1016/j.bbmt.2008.02.006","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2008.02.006","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bbmt.2008.02.006","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043966208","display_name":"Hugo R Castro-Malaspina","orcid":"https://orcid.org/0000-0002-9956-904X","observed_orcids":["https://orcid.org/0000-0002-9956-904X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hugo Castro-Malaspina","raw_affiliation_strings":["The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. castro-h@mskcc.org","The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. castro-h@mskcc.org","institution_ids":["https://openalex.org/I1334819555"]},{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063378852","display_name":"Ann A. Jabubowski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ann A. Jabubowski","raw_affiliation_strings":["The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058746837","display_name":"Esperanza Bouza Papadopoulos","orcid":"https://orcid.org/0000-0001-6066-1861","observed_orcids":["https://orcid.org/0000-0001-6066-1861"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Esperanza B. Papadopoulos","raw_affiliation_strings":["The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067712388","display_name":"Farid Boulad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farid Boulad","raw_affiliation_strings":["Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036520753","display_name":"James W. Young","orcid":"https://orcid.org/0000-0002-0032-6559","observed_orcids":["https://orcid.org/0000-0002-0032-6559"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James W. Young","raw_affiliation_strings":["The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079103223","display_name":"Nancy A. Kernan","orcid":"https://orcid.org/0000-0003-1417-1823","observed_orcids":["https://orcid.org/0000-0003-1417-1823"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy A. Kernan","raw_affiliation_strings":["Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082333371","display_name":"Miguel\u2010Angel Perales","orcid":"https://orcid.org/0000-0002-5910-4571","observed_orcids":["https://orcid.org/0000-0002-5910-4571"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miguel A. Perales","raw_affiliation_strings":["The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110131284","display_name":"Trudy N. Small","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trudy N. Small","raw_affiliation_strings":["Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056539557","display_name":"Katharine C. Hsu","orcid":"https://orcid.org/0000-0003-2827-5324","observed_orcids":["https://orcid.org/0000-0003-2827-5324"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katharine Hsu","raw_affiliation_strings":["The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056264617","display_name":"Michelle Chiu","orcid":"https://orcid.org/0009-0008-6282-5872","observed_orcids":["https://orcid.org/0009-0008-6282-5872"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle Chiu","raw_affiliation_strings":["Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031035765","display_name":"Glenn Heller","orcid":"https://orcid.org/0000-0001-9217-8348","observed_orcids":["https://orcid.org/0000-0001-9217-8348"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Glenn Heller","raw_affiliation_strings":["Department of Epidemiology and Statistics, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Statistics, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112250132","display_name":"Nancy Collins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy H. Collins","raw_affiliation_strings":["Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111962356","display_name":"Suresh C. Jhanwar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suresh C. Jhanwar","raw_affiliation_strings":["Cytogenetics Laboratory, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytogenetics Laboratory, Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003503263","display_name":"Marcel R.M. van den Brink","orcid":"https://orcid.org/0000-0003-0696-4401","observed_orcids":["https://orcid.org/0000-0003-0696-4401"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcel van den Brink","raw_affiliation_strings":["The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Allogeneic Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020996374","display_name":"Stephen D. Nimer","orcid":"https://orcid.org/0000-0003-2439-7586","observed_orcids":["https://orcid.org/0000-0003-2439-7586"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen D. Nimer","raw_affiliation_strings":["Hematology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hematology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108531125","display_name":"Richard J. O\u2019Reilly","orcid":"https://orcid.org/0000-0002-8997-5490","observed_orcids":["https://orcid.org/0000-0002-8997-5490"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard J. O'Reilly","raw_affiliation_strings":["Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bone Marrow Transplantation Service, Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5043966208"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":2.5083,"has_fulltext":false,"cited_by_count":64,"citation_normalized_percentile":{"value":0.89825733,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"14","issue":"4","first_page":"458","last_page":"468"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12900","display_name":"Organ and Tissue Transplantation Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myelodysplastic-syndrome","display_name":"myelodysplastic syndrome","score":0.9810000061988831},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.8199999928474426},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.9359999895095825},{"id":"https://openalex.org/keywords/hla-identical-siblings","display_name":"HLA-identical siblings","score":0.7070000171661377},{"id":"https://openalex.org/keywords/myeloablative-conditioning","display_name":"myeloablative conditioning","score":0.8600000143051147},{"id":"https://openalex.org/keywords/total-body-irradiation","display_name":"total body irradiation","score":0.8920000195503235},{"id":"https://openalex.org/keywords/busulfan","display_name":"busulfan","score":0.9860000014305115},{"id":"https://openalex.org/keywords/t-cell-depletion","display_name":"T cell depletion","score":0.8040000200271606},{"id":"https://openalex.org/keywords/hematological-remission","display_name":"hematologic remission","score":0.8059999942779541},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.9210000038146973},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.7450000047683716},{"id":"https://openalex.org/keywords/treatment-related-mortality","display_name":"non-relapse mortality","score":0.9649999737739563},{"id":"https://openalex.org/keywords/graft-versus-host-disease","display_name":"graft-versus-host disease","score":0.9079999923706055},{"id":"https://openalex.org/keywords/engraftment","display_name":"engraftment","score":0.7789999842643738},{"id":"https://openalex.org/keywords/cytoreduction","display_name":"cytoreduction","score":0.4410000145435333}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9441721439361572},{"id":"https://openalex.org/C2780611847","wikidata":"https://www.wikidata.org/wiki/Q348922","display_name":"Busulfan","level":4,"score":0.7975548505783081},{"id":"https://openalex.org/C88879693","wikidata":"https://www.wikidata.org/wiki/Q217690","display_name":"Cumulative incidence","level":3,"score":0.7075485587120056},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.681071937084198},{"id":"https://openalex.org/C2780366003","wikidata":"https://www.wikidata.org/wiki/Q246147","display_name":"Cytopenia","level":3,"score":0.6695032715797424},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6515616178512573},{"id":"https://openalex.org/C2778880498","wikidata":"https://www.wikidata.org/wiki/Q1986672","display_name":"Total body irradiation","level":4,"score":0.585344672203064},{"id":"https://openalex.org/C2780817109","wikidata":"https://www.wikidata.org/wiki/Q954625","display_name":"Myelodysplastic syndromes","level":3,"score":0.5761715173721313},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.551364004611969},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.49671703577041626},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.45271575450897217},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.42076021432876587},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.3346083462238312},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.2619551420211792}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006086","descriptor_name":"Graft vs Host Disease","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008212","descriptor_name":"Lymphocyte Depletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009190","descriptor_name":"Myelodysplastic Syndromes","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014185","descriptor_name":"Transplantation, Isogeneic","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D014916","descriptor_name":"Whole-Body Irradiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019172","descriptor_name":"Transplantation Conditioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D033581","descriptor_name":"Stem Cell Transplantation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D035781","descriptor_name":"Siblings","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.bbmt.2008.02.006","doi":"https://doi.org/10.1016/j.bbmt.2008.02.006","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2008.02.006","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},{"id":"pmid:18342789","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18342789","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3462258","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4498391","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4498391","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4498391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biol Blood Marrow Transplant","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.bbmt.2008.02.006","doi":"https://doi.org/10.1016/j.bbmt.2008.02.006","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bbmt.2008.02.006","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Blood and Marrow Transplantation","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1574533925","display_name":"Immunobiology of Allogeneic Hematopoietic Cell Transplantation","funder_award_id":"P01CA023766","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5034797156","display_name":"NK Tolerance and Hematopoietic Cell Transplantation","funder_award_id":"R01HL088134","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G9000856728","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA008748","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W35202944","https://openalex.org/W85833199","https://openalex.org/W100647374","https://openalex.org/W116615943","https://openalex.org/W149003550","https://openalex.org/W162809425","https://openalex.org/W187238933","https://openalex.org/W227961483","https://openalex.org/W256080963","https://openalex.org/W1487950379","https://openalex.org/W1493021534","https://openalex.org/W1513084177","https://openalex.org/W1530764705","https://openalex.org/W1545991364","https://openalex.org/W1707184873","https://openalex.org/W1711791220","https://openalex.org/W1856810180","https://openalex.org/W1873141201","https://openalex.org/W1973617793","https://openalex.org/W1979300931","https://openalex.org/W1980927128","https://openalex.org/W1983344261","https://openalex.org/W1991125854","https://openalex.org/W1992090010","https://openalex.org/W2005400572","https://openalex.org/W2012548375","https://openalex.org/W2022978986","https://openalex.org/W2030452018","https://openalex.org/W2039808932","https://openalex.org/W2041544514","https://openalex.org/W2045229166","https://openalex.org/W2046465273","https://openalex.org/W2047533297","https://openalex.org/W2055937634","https://openalex.org/W2056644883","https://openalex.org/W2062506977","https://openalex.org/W2069566335","https://openalex.org/W2073140442","https://openalex.org/W2076937813","https://openalex.org/W2078301067","https://openalex.org/W2078790776","https://openalex.org/W2080826082","https://openalex.org/W2092673055","https://openalex.org/W2096793413","https://openalex.org/W2099384791","https://openalex.org/W2100748266","https://openalex.org/W2103628120","https://openalex.org/W2106947293","https://openalex.org/W2108828724","https://openalex.org/W2123434358","https://openalex.org/W2128912851","https://openalex.org/W2129510594","https://openalex.org/W2136016420","https://openalex.org/W2139984188","https://openalex.org/W2142845100","https://openalex.org/W2144897379","https://openalex.org/W2146744909","https://openalex.org/W2147083172","https://openalex.org/W2151704978","https://openalex.org/W2159507916","https://openalex.org/W2161326960","https://openalex.org/W2161872048","https://openalex.org/W2172296959","https://openalex.org/W2206561315","https://openalex.org/W2247784410","https://openalex.org/W2271039096","https://openalex.org/W2278599555","https://openalex.org/W2335673657","https://openalex.org/W2398820891","https://openalex.org/W2406313600","https://openalex.org/W2408278513","https://openalex.org/W2410096256","https://openalex.org/W2413054781","https://openalex.org/W2416437448","https://openalex.org/W3041047318","https://openalex.org/W3147894994"],"related_works":["https://openalex.org/W2512017993","https://openalex.org/W4241779594","https://openalex.org/W1513084177","https://openalex.org/W7099218786","https://openalex.org/W2078301067","https://openalex.org/W1991125854","https://openalex.org/W1971100781","https://openalex.org/W2069566335","https://openalex.org/W4406830963","https://openalex.org/W2278599555"],"abstract_inverted_index":{"From":[0],"1985":[1],"to":[2,79,104],"2004,":[3],"49":[4,142],"patients":[5,58,72,86,143,157,291],"with":[6,42,221,292,307],"advanced":[7,293],"myelodysplastic":[8],"syndromes":[9],"(MDS)":[10],"(>":[11],"or":[12,15,29,53,114,285,301],"=5%":[13],"blasts)":[14],"acute":[16,159],"myeloid":[17],"leukemia":[18],"(AML)":[19],"transformed":[20],"from":[21,37],"MDS":[22,118,294],"underwent":[23],"T":[24,319],"cell":[25,34,320],"depleted":[26,321],"bone":[27],"marrow":[28],"peripheral":[30],"blood":[31],"hematopoietic":[32],"stem":[33],"transplantation":[35],"(HSCT)":[36],"HLA-identical":[38],"siblings":[39],"following":[40,316],"conditioning":[41,310],"a":[43,94,278,302,317],"myeloablative":[44,318],"regimen":[45],"that":[46,290],"included":[47],"total":[48],"body":[49],"irradiation":[50],"(44":[51],"patients)":[52],"busulfan":[54],"(5":[55],"patients).":[56],"Thirty-six":[57],"received":[59],"chemotherapy":[60,308],"(3":[61],"low":[62],"dose":[63],"and":[64,70,107,150,164,166,189,204,244,269,297],"33":[65],"induction":[66],"doses)":[67],"before":[68,153,216,309],"conditioning,":[69],"13":[71],"did":[73],"not":[74],"receive":[75],"any":[76],"chemotherapy.":[77],"Prior":[78],"transplantation,":[80],"22":[81],"of":[82,109,116,140,228,252,283],"the":[83,110,141,175,182,186,192,234,239,246,259,264,271],"36":[84],"treated":[85],"were":[87,92],"in":[88,93,181,185,191,206,299],"hematologic":[89],"remission;":[90,106],"4":[91],"second":[95,303],"refractory":[96,304],"cytopenia":[97,305],"phase":[98,306],"(26":[99],"responders);":[100],"8":[101],"had":[102,112,146],"failed":[103],"achieve":[105,296,312],"2":[108,145,151],"responders":[111,235,260],"progression":[113],"relapse":[115,229],"their":[117],"(10":[119],"failures).":[120],"No":[121],"post-transplantation":[122,232],"pharmacologic":[123],"prophylaxis":[124],"for":[125,233,238,245,258,263,270],"graft-versus-host":[126],"disease":[127,197,214],"(GVHD)":[128],"was":[129,134,179,201,236,242,248,261,267,273],"given.":[130],"The":[131,196,224,250],"median":[132],"age":[133],"48":[135],"yrs":[136,173],"(range":[137],"13-61).":[138],"Forty-five":[139],"engrafted;":[144],"primary":[147],"graft":[148],"failure;":[149],"died":[152],"engraftment.":[154],"Only":[155],"3":[156,172],"developed":[158],"GVHD":[160,169],"(aGVHD)":[161],"(grades":[162],"I":[163],"III)":[165],"1":[167],"chronic":[168],"(cGVHD).":[170],"At":[171],"post-transplantation,":[174,257],"overall":[176],"survival":[177,199],"(OS)":[178],"54%":[180],"responders;":[183],"31%":[184],"untreated":[187,240,265],"group;":[188],"0%":[190,205],"failure":[193],"group":[194,208,241,266],"(P=.0004).":[195],"free":[198],"(DFS)":[200],"50%,":[202],"15%":[203],"each":[207],"respectively":[209],"(P=.0008).":[210],"In":[211],"multivariate":[212],"analysis,":[213],"status":[215],"cytoreduction":[217],"remained":[218],"highly":[219],"correlated":[220],"DFS":[222],"(P<.001).":[223],"cumulative":[225],"incidence":[226],"(CI)":[227],"at":[230,255],"2-yrs":[231,256],"23%;":[237,262],"38%;":[243,268],"failures":[247,272],"50%.":[249],"CI":[251],"non-relapse":[253],"mortality":[254],"40%.":[274],"All":[275],"survivors":[276],"achieved":[277],"Karnofsky":[279],"Performance":[280],"Status":[281],"(KPS)":[282],">":[284],"=90.":[286],"These":[287],"results":[288],"indicate":[289],"who":[295],"remain":[298],"remission":[300],"can":[311],"successful":[313],"long-term":[314],"remissions":[315],"allogeneic":[322],"HSCT.":[323]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
