{"id":"https://openalex.org/W2156463549","doi":"https://doi.org/10.1093/schbul/sbt198","title":"Differential Neurodevelopmental Trajectories in Patients With Early-Onset Bipolar and Schizophrenia Disorders","display_name":"Differential Neurodevelopmental Trajectories in Patients With Early-Onset Bipolar and Schizophrenia Disorders","publication_year":2013,"publication_date":"2013-12-26","ids":{"openalex":"https://openalex.org/W2156463549","doi":"https://doi.org/10.1093/schbul/sbt198","mag":"2156463549","pmid":"https://pubmed.ncbi.nlm.nih.gov/24371326","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3934406"},"language":"en","primary_location":{"id":"doi:10.1093/schbul/sbt198","doi":"https://doi.org/10.1093/schbul/sbt198","is_oa":true,"landing_page_url":"https://doi.org/10.1093/schbul/sbt198","pdf_url":"https://academic.oup.com/schizophreniabulletin/article-pdf/40/Suppl_2/S138/5448778/sbt198.pdf","source":{"id":"https://openalex.org/S117485531","display_name":"Schizophrenia Bulletin","issn_l":"0586-7614","issn":["0586-7614","1745-1701","1745-1707"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/schizophreniabulletin/article-pdf/40/Suppl_2/S138/5448778/sbt198.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002872855","display_name":"Celso Arango","orcid":"https://orcid.org/0000-0003-3382-4754","observed_orcids":["https://orcid.org/0000-0003-3382-4754"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I2960094004","display_name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n","ror":"https://ror.org/0111es613","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2960094004","https://openalex.org/I4210139293"]},{"id":"https://openalex.org/I4210090703","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental","ror":"https://ror.org/009byq155","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210090703","https://openalex.org/I4387152914"]}],"countries":["ES","US"],"is_corresponding":true,"raw_author_name":"C. Arango","raw_affiliation_strings":["*To whom correspondence should be addressed; Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Ibiza 43, 28009 Madrid, Spain; tel: 34-914265006; fax: 34-91426004, e-mail: carango@mprc.umaryland.edu","Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Madrid, Spain","Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*To whom correspondence should be addressed; Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Ibiza 43, 28009 Madrid, Spain; tel: 34-914265006; fax: 34-91426004, e-mail: carango@mprc.umaryland.edu","institution_ids":["https://openalex.org/I2960094004"]},{"raw_affiliation_string":"Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Madrid, Spain","institution_ids":["https://openalex.org/I2960094004","https://openalex.org/I4210090703"]},{"raw_affiliation_string":"Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland, School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I126744593"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033941728","display_name":"David Fraguas","orcid":"https://orcid.org/0000-0002-7931-2933","observed_orcids":["https://orcid.org/0000-0002-7931-2933"]},"institutions":[{"id":"https://openalex.org/I2960094004","display_name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n","ror":"https://ror.org/0111es613","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2960094004","https://openalex.org/I4210139293"]},{"id":"https://openalex.org/I4210090703","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental","ror":"https://ror.org/009byq155","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210090703","https://openalex.org/I4387152914"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"D. Fraguas","raw_affiliation_strings":["Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Madrid, Spain","institution_ids":["https://openalex.org/I2960094004","https://openalex.org/I4210090703"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027816426","display_name":"Mara Parellada","orcid":"https://orcid.org/0000-0001-7977-3601","observed_orcids":["https://orcid.org/0000-0001-7977-3601"]},"institutions":[{"id":"https://openalex.org/I2960094004","display_name":"Hospital General Universitario Gregorio Mara\u00f1\u00f3n","ror":"https://ror.org/0111es613","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I2960094004","https://openalex.org/I4210139293"]},{"id":"https://openalex.org/I4210090703","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental","ror":"https://ror.org/009byq155","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210090703","https://openalex.org/I4387152914"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. Parellada","raw_affiliation_strings":["Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Madrid, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Child and Adolescent Psychiatry Department, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, IiSGM, School of Medicine, Universidad Complutense, CIBERSAM, Madrid, Spain","institution_ids":["https://openalex.org/I2960094004","https://openalex.org/I4210090703"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5002872855"],"corresponding_institution_ids":["https://openalex.org/I126744593","https://openalex.org/I2960094004","https://openalex.org/I4210090703"],"apc_list":{"value":4981,"currency":"USD","value_usd":4981},"apc_paid":null,"fwci":8.9665,"has_fulltext":true,"cited_by_count":119,"citation_normalized_percentile":{"value":0.98518065,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"40","issue":"Suppl 2","first_page":"S138","last_page":"S146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.5317000150680542,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":0.5317000150680542,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.46389999985694885,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10565","display_name":"Psychopathy, Forensic Psychiatry, Sexual Offending","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-onset-bipolar-disorder","display_name":"early-onset bipolar disorder","score":0.8679999709129333},{"id":"https://openalex.org/keywords/early-onset-schizophrenia","display_name":"early-onset schizophrenia","score":0.9829999804496765}],"concepts":[{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.7879629135131836},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6943621635437012},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5950125455856323},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5687704086303711},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.5033301711082458},{"id":"https://openalex.org/C2777767895","wikidata":"https://www.wikidata.org/wiki/Q4691924","display_name":"Age of onset","level":3,"score":0.49522843956947327},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.48460397124290466},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.42811524868011475},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3361486494541168},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.19699707627296448},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1347232162952423},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.07155105471611023}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001714","descriptor_name":"Bipolar Disorder","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D001714","descriptor_name":"Bipolar Disorder","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001714","descriptor_name":"Bipolar Disorder","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002658","descriptor_name":"Developmental Disabilities","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D002658","descriptor_name":"Developmental Disabilities","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002658","descriptor_name":"Developmental Disabilities","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D017668","descriptor_name":"Age of Onset","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1093/schbul/sbt198","doi":"https://doi.org/10.1093/schbul/sbt198","is_oa":true,"landing_page_url":"https://doi.org/10.1093/schbul/sbt198","pdf_url":"https://academic.oup.com/schizophreniabulletin/article-pdf/40/Suppl_2/S138/5448778/sbt198.pdf","source":{"id":"https://openalex.org/S117485531","display_name":"Schizophrenia Bulletin","issn_l":"0586-7614","issn":["0586-7614","1745-1701","1745-1707"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Bulletin","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:3307001","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3934406","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3934406","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3934406","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophr Bull","raw_type":"Text"},{"id":"pmid:24371326","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24371326","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia bulletin","raw_type":"Comparative Study"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.842.3998","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.842.3998","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://schizophreniabulletin.oxfordjournals.org/content/40/Suppl_2/S138.full.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.857.6630","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.857.6630","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://schizophreniabulletin.oxfordjournals.org/content/early/2013/12/25/schbul.sbt198.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1093/schbul/sbt198","doi":"https://doi.org/10.1093/schbul/sbt198","is_oa":true,"landing_page_url":"https://doi.org/10.1093/schbul/sbt198","pdf_url":"https://academic.oup.com/schizophreniabulletin/article-pdf/40/Suppl_2/S138/5448778/sbt198.pdf","source":{"id":"https://openalex.org/S117485531","display_name":"Schizophrenia Bulletin","issn_l":"0586-7614","issn":["0586-7614","1745-1701","1745-1707"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","erih-plus","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Schizophrenia Bulletin","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2166355479","display_name":null,"funder_award_id":"S2010/BMD-2422 AGES","funder_id":"https://openalex.org/F4320321837","funder_display_name":"Ministerio de Econom\u00eda y Competitividad"},{"id":"https://openalex.org/G2203834002","display_name":null,"funder_award_id":"RETICS RD06/0011","funder_id":"https://openalex.org/F4320324085","funder_display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental"},{"id":"https://openalex.org/G2864489294","display_name":null,"funder_award_id":"S2010/BMD-2422","funder_id":"https://openalex.org/F4320322930","funder_display_name":"Ministerio de Ciencia e Innovaci\u00f3n"},{"id":"https://openalex.org/G3558093645","display_name":null,"funder_award_id":"S2010/BMD-2422 AGES","funder_id":"https://openalex.org/F4320324085","funder_display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental"},{"id":"https://openalex.org/G5381086300","display_name":null,"funder_award_id":"S2010/BMD-2422 AGES","funder_id":"https://openalex.org/F4320310220","funder_display_name":"Fundaci\u00f3n Mutua Madrile\u00f1a"},{"id":"https://openalex.org/G7192275438","display_name":null,"funder_award_id":"2422 AGES","funder_id":"https://openalex.org/F4320310221","funder_display_name":"Fundaci\u00f3n Alicia Koplowitz"},{"id":"https://openalex.org/G7477515177","display_name":null,"funder_award_id":"S2010/BMD","funder_id":"https://openalex.org/F4320310221","funder_display_name":"Fundaci\u00f3n Alicia Koplowitz"},{"id":"https://openalex.org/G795849684","display_name":null,"funder_award_id":"RETICS RD06/0011","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"},{"id":"https://openalex.org/G804650661","display_name":null,"funder_award_id":"RD06/0011","funder_id":"https://openalex.org/F4320334923","funder_display_name":"Instituto de Salud Carlos III"}],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320310220","display_name":"Fundaci\u00f3n Mutua Madrile\u00f1a","ror":"https://ror.org/00skv9577"},{"id":"https://openalex.org/F4320310221","display_name":"Fundaci\u00f3n Alicia Koplowitz","ror":"https://ror.org/036jhs482"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321837","display_name":"Ministerio de Econom\u00eda y Competitividad","ror":"https://ror.org/034900433"},{"id":"https://openalex.org/F4320322930","display_name":"Ministerio de Ciencia e Innovaci\u00f3n","ror":null},{"id":"https://openalex.org/F4320324085","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental","ror":"https://ror.org/009byq155"},{"id":"https://openalex.org/F4320327235","display_name":"Servier","ror":"https://ror.org/034e7c066"},{"id":"https://openalex.org/F4320327918","display_name":"H. Lundbeck A/S","ror":"https://ror.org/0564cd633"},{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"},{"id":"https://openalex.org/F4320338413","display_name":"Cilag","ror":"https://ror.org/02fe4h741"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2156463549.pdf","grobid_xml":"https://content.openalex.org/works/W2156463549.grobid-xml"},"referenced_works_count":99,"referenced_works":["https://openalex.org/W2161253","https://openalex.org/W186955538","https://openalex.org/W1555460522","https://openalex.org/W1576436901","https://openalex.org/W1887731522","https://openalex.org/W1900447338","https://openalex.org/W1923168292","https://openalex.org/W1965724486","https://openalex.org/W1970520385","https://openalex.org/W1971093376","https://openalex.org/W1974435463","https://openalex.org/W1981253098","https://openalex.org/W1981463159","https://openalex.org/W1984944505","https://openalex.org/W1987697056","https://openalex.org/W1995362640","https://openalex.org/W1996474046","https://openalex.org/W2004469093","https://openalex.org/W2006124435","https://openalex.org/W2010562917","https://openalex.org/W2018886916","https://openalex.org/W2020575476","https://openalex.org/W2024048695","https://openalex.org/W2024341316","https://openalex.org/W2025011978","https://openalex.org/W2025631284","https://openalex.org/W2026016859","https://openalex.org/W2026085089","https://openalex.org/W2026122923","https://openalex.org/W2031355868","https://openalex.org/W2032207621","https://openalex.org/W2037283239","https://openalex.org/W2039067474","https://openalex.org/W2041042823","https://openalex.org/W2041198871","https://openalex.org/W2042850046","https://openalex.org/W2049991030","https://openalex.org/W2052891323","https://openalex.org/W2053107171","https://openalex.org/W2054998761","https://openalex.org/W2056370816","https://openalex.org/W2056373644","https://openalex.org/W2057853969","https://openalex.org/W2059747380","https://openalex.org/W2084722042","https://openalex.org/W2084792810","https://openalex.org/W2088786313","https://openalex.org/W2092752685","https://openalex.org/W2098597355","https://openalex.org/W2099292447","https://openalex.org/W2100570947","https://openalex.org/W2100784423","https://openalex.org/W2106131962","https://openalex.org/W2108327881","https://openalex.org/W2110945341","https://openalex.org/W2113673814","https://openalex.org/W2118257231","https://openalex.org/W2120896455","https://openalex.org/W2123593542","https://openalex.org/W2124524555","https://openalex.org/W2127679160","https://openalex.org/W2131837410","https://openalex.org/W2132716644","https://openalex.org/W2134893852","https://openalex.org/W2136112923","https://openalex.org/W2136989399","https://openalex.org/W2138204048","https://openalex.org/W2138516825","https://openalex.org/W2139852368","https://openalex.org/W2144031424","https://openalex.org/W2144081409","https://openalex.org/W2144315007","https://openalex.org/W2144319186","https://openalex.org/W2148406811","https://openalex.org/W2148953407","https://openalex.org/W2152192725","https://openalex.org/W2153549503","https://openalex.org/W2153565635","https://openalex.org/W2154100681","https://openalex.org/W2155851745","https://openalex.org/W2156107504","https://openalex.org/W2158256980","https://openalex.org/W2162950935","https://openalex.org/W2163414567","https://openalex.org/W2163525833","https://openalex.org/W2163631388","https://openalex.org/W2164138343","https://openalex.org/W2165043737","https://openalex.org/W2166890298","https://openalex.org/W2167503370","https://openalex.org/W2169716279","https://openalex.org/W2169951970","https://openalex.org/W2170008023","https://openalex.org/W2171396692","https://openalex.org/W2179769211","https://openalex.org/W2247243137","https://openalex.org/W4211063728","https://openalex.org/W4213324539","https://openalex.org/W4247872186"],"related_works":["https://openalex.org/W2763058017","https://openalex.org/W2018886916","https://openalex.org/W1490183240","https://openalex.org/W2092752685","https://openalex.org/W2144315007","https://openalex.org/W1910771706","https://openalex.org/W2586667007","https://openalex.org/W2040448293","https://openalex.org/W2346516757","https://openalex.org/W3004707186"],"abstract_inverted_index":{"Schizophrenia":[0],"and":[1,18,28,50,119,150,189],"bipolar":[2,60,66,81,98,158],"disorders":[3],"share":[4,86],"not":[5],"only":[6],"clinical":[7],"features":[8,175],"but":[9],"also":[10,57],"some":[11,87,163],"risk":[12,23],"factors":[13,24],"such":[14,25],"as":[15,26],"genetic":[16],"markers":[17],"childhood":[19,155],"adversity,":[20],"while":[21],"other":[22],"urbanicity":[27],"obstetric":[29],"complications":[30],"seem":[31,84,139],"to":[32,35,85,130,140,172,185],"be":[33],"specific":[34],"schizophrenia.":[36,94],"An":[37],"intriguing":[38],"question":[39],"is":[40,56,68],"whether":[41],"the":[42,112,173],"well-established":[43],"abnormal":[44,166],"neurodevelopment":[45],"present":[46,58],"in":[47,59,126,154],"many":[48],"children":[49],"adolescents":[51],"who":[52,83],"eventually":[53],"develop":[54],"schizophrenia":[55,132,138],"patients.":[61,159],"The":[62],"literature":[63],"on":[64,73],"adult":[65],"patients":[67,77,91,99,135],"controversial.":[69],"We":[70,160],"report":[71],"data":[72],"a":[74,127],"subgroup":[75],"of":[76,114,164,180,192],"with":[78,90,92,136],"pediatric-onset":[79],"psychotic":[80,97,117,178],"disorder":[82],"developmental":[88,145,167],"trajectories":[89,168],"early-onset":[93,96,131,137,157,177],"These":[95],"have":[100,141],"low":[101],"intelligence":[102],"quotient,":[103],"more":[104,142,170],"neurological":[105],"signs,":[106],"reduced":[107],"frontal":[108],"gray":[109],"matter":[110],"at":[111],"time":[113],"their":[115],"first":[116],"episode,":[118],"greater":[120],"brain":[121],"changes":[122],"than":[123,156,184],"healthy":[124],"controls":[125],"pattern":[128],"similar":[129],"cases.":[133],"However,":[134],"social":[143],"impairment,":[144],"abnormalities":[146],"(eg,":[147,176],"language":[148],"problems),":[149],"lower":[151],"academic":[152],"achievement":[153],"suggest":[161],"that":[162],"these":[165,181],"are":[169],"related":[171],"phenotypic":[174],"symptoms)":[179],"2":[182],"syndromes":[183],"categorically":[186],"defined":[187],"Diagnostic":[188],"Statistical":[190],"Manual":[191],"Mental":[193],"Disorders":[194],"disorders.":[195]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":11},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":13},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
