{"id":"https://openalex.org/W2156239059","doi":"https://doi.org/10.1136/ard.2010.143347","title":"Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis (ACUTE\u2013JIA): a multicentre randomised open-label clinical trial","display_name":"Aggressive Combination Drug Therapy in Very Early Polyarticular Juvenile Idiopathic Arthritis (ACUTE\u2013JIA): a multicentre randomised open-label clinical trial","publication_year":2011,"publication_date":"2011-05-30","ids":{"openalex":"https://openalex.org/W2156239059","doi":"https://doi.org/10.1136/ard.2010.143347","mag":"2156239059","pmid":"https://pubmed.ncbi.nlm.nih.gov/21623000"},"language":"en","primary_location":{"id":"doi:10.1136/ard.2010.143347","doi":"https://doi.org/10.1136/ard.2010.143347","is_oa":false,"landing_page_url":"https://doi.org/10.1136/ard.2010.143347","pdf_url":null,"source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065732956","display_name":"Pirjo Tynj\u00e4l\u00e4","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I4210090554","display_name":"Helsinki Children's Hospital","ror":"https://ror.org/00dqfzf20","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210090554","https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Pirjo Tynj\u00e4l\u00e4","raw_affiliation_strings":["Department of Pediatric Rheumatology, Children\u2019s Hospital, Helsinki University Central Hospital, Helsinki, Finland. pirjo.tynjala@hus.fi","Research Unit, Hospital for Children and Adolescents, Biomedicum 2C Helsinki, PB 705, 00029 Hus, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Rheumatology, Children\u2019s Hospital, Helsinki University Central Hospital, Helsinki, Finland. pirjo.tynjala@hus.fi","institution_ids":["https://openalex.org/I2800394112","https://openalex.org/I4210090554"]},{"raw_affiliation_string":"Research Unit, Hospital for Children and Adolescents, Biomedicum 2C Helsinki, PB 705, 00029 Hus, Finland","institution_ids":["https://openalex.org/I4210090554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077144329","display_name":"Paula V\u00e4h\u00e4salo","orcid":"https://orcid.org/0000-0002-2712-3903","observed_orcids":["https://orcid.org/0000-0002-2712-3903"]},"institutions":[{"id":"https://openalex.org/I2799272722","display_name":"Oulu University Hospital","ror":"https://ror.org/045ney286","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2799272722"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Paula V\u00e4h\u00e4salo","raw_affiliation_strings":["Department of Pediatrics, Oulu University Hospital, Oulu, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Oulu University Hospital, Oulu, Finland","institution_ids":["https://openalex.org/I2799272722"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023777249","display_name":"Maarit Tarkiainen","orcid":"https://orcid.org/0000-0002-1569-5349","observed_orcids":["https://orcid.org/0000-0002-1569-5349"]},"institutions":[{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I4210090554","display_name":"Helsinki Children's Hospital","ror":"https://ror.org/00dqfzf20","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210090554","https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Maarit Tarkiainen","raw_affiliation_strings":["Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland","institution_ids":["https://openalex.org/I2800394112","https://openalex.org/I4210090554"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Liisa Kr\u00f6ger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210092991","display_name":"Kuopio University Hospital","ror":"https://ror.org/00fqdfs68","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210092991","https://openalex.org/I4405278559"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Liisa Kr\u00f6ger","raw_affiliation_strings":["Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Kuopio University Hospital, Kuopio, Finland","institution_ids":["https://openalex.org/I4210092991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035781724","display_name":"Kristiina T Aalto","orcid":"https://orcid.org/0000-0002-5285-0424","observed_orcids":["https://orcid.org/0000-0002-5285-0424"]},"institutions":[{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I4210090554","display_name":"Helsinki Children's Hospital","ror":"https://ror.org/00dqfzf20","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210090554","https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Kristiina Aalto","raw_affiliation_strings":["Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland","institution_ids":["https://openalex.org/I2800394112","https://openalex.org/I4210090554"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027337007","display_name":"M. Malin","orcid":"https://orcid.org/0009-0008-2155-8480","observed_orcids":["https://orcid.org/0009-0008-2155-8480"]},"institutions":[{"id":"https://openalex.org/I4210126318","display_name":"Tampere University Hospital","ror":"https://ror.org/02hvt5f17","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I4210126318"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Merja Malin","raw_affiliation_strings":["Department of Pediatrics, Tampere University Hospital, Tampere, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Tampere University Hospital, Tampere, Finland","institution_ids":["https://openalex.org/I4210126318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081796517","display_name":"Anne Putto\u2010Laurila","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801970007","display_name":"Turku University Hospital","ror":"https://ror.org/05dbzj528","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2801970007","https://openalex.org/I4210127022"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Anne Putto-Laurila","raw_affiliation_strings":["Department of Pediatrics, Turku University Hospital, Turku, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Turku University Hospital, Turku, Finland","institution_ids":["https://openalex.org/I2801970007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046115881","display_name":"Visa Honkanen","orcid":"https://orcid.org/0000-0003-3428-4307","observed_orcids":["https://orcid.org/0000-0003-3428-4307"]},"institutions":[{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I4210090554","display_name":"Helsinki Children's Hospital","ror":"https://ror.org/00dqfzf20","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210090554","https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Visa Honkanen","raw_affiliation_strings":["Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland","institution_ids":["https://openalex.org/I2800394112","https://openalex.org/I4210090554"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071510702","display_name":"Pekka Lahdenne","orcid":"https://orcid.org/0000-0002-3983-2897","observed_orcids":["https://orcid.org/0000-0002-3983-2897"]},"institutions":[{"id":"https://openalex.org/I2800394112","display_name":"Helsinki University Hospital","ror":"https://ror.org/02e8hzf44","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210166427"]},{"id":"https://openalex.org/I4210090554","display_name":"Helsinki Children's Hospital","ror":"https://ror.org/00dqfzf20","country_code":"FI","type":"healthcare","lineage":["https://openalex.org/I2800394112","https://openalex.org/I4210090554","https://openalex.org/I4210166427"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Pekka Lahdenne","raw_affiliation_strings":["Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Rheumatology, Children's Hospital, Helsinki University Central Hospital, Helsinki, Finland","institution_ids":["https://openalex.org/I2800394112","https://openalex.org/I4210090554"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5065732956"],"corresponding_institution_ids":["https://openalex.org/I2800394112","https://openalex.org/I4210090554"],"apc_list":{"value":4870,"currency":"USD","value_usd":4870},"apc_paid":null,"fwci":11.8863,"has_fulltext":false,"cited_by_count":229,"citation_normalized_percentile":{"value":0.98863984,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"70","issue":"9","first_page":"1605","last_page":"1612"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/juvenile-idiopathic-arthritis","display_name":"juvenile idiopathic arthritis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/polyarticular-jia","display_name":"polyarticular JIA","score":0.8769999742507935},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7149999737739563},{"id":"https://openalex.org/keywords/infliximab","display_name":"infliximab","score":0.9599999785423279},{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.9700000286102295},{"id":"https://openalex.org/keywords/sulfasalazine","display_name":"sulfasalazine","score":0.9110000133514404},{"id":"https://openalex.org/keywords/hydroxychloroquine","display_name":"hydroxychloroquine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/tnf-alpha-inhibitors","display_name":"TNF-alpha inhibitors","score":0.6949999928474426},{"id":"https://openalex.org/keywords/dmard-naive-patients","display_name":"DMARD-naive patients","score":0.8140000104904175},{"id":"https://openalex.org/keywords/inactive-disease","display_name":"inactive disease","score":0.9470000267028809},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.3659999966621399},{"id":"https://openalex.org/keywords/adverse-events","display_name":"adverse events","score":0.7570000290870667},{"id":"https://openalex.org/keywords/pediatric-rheumatology","display_name":"pediatric rheumatology","score":0.8230000138282776}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9692260026931763},{"id":"https://openalex.org/C2781059491","wikidata":"https://www.wikidata.org/wiki/Q422232","display_name":"Methotrexate","level":2,"score":0.7787895202636719},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7294424772262573},{"id":"https://openalex.org/C2779123688","wikidata":"https://www.wikidata.org/wiki/Q421094","display_name":"Hydroxychloroquine","level":5,"score":0.6520287394523621},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.5595123767852783},{"id":"https://openalex.org/C2777138892","wikidata":"https://www.wikidata.org/wiki/Q415264","display_name":"Infliximab","level":3,"score":0.55262291431427},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.5429354906082153},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.5353956818580627},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.48137810826301575},{"id":"https://openalex.org/C2777226972","wikidata":"https://www.wikidata.org/wiki/Q415343","display_name":"Etanercept","level":3,"score":0.46714162826538086},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.41596999764442444},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3747871518135071},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.32775741815567017},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.22271102666854858},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000069285","descriptor_name":"Infliximab","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001171","descriptor_name":"Arthritis, Juvenile","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004338","descriptor_name":"Drug Combinations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004812","descriptor_name":"Epidemiologic Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005938","descriptor_name":"Glucocorticoids","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006886","descriptor_name":"Hydroxychloroquine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D006886","descriptor_name":"Hydroxychloroquine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D007270","descriptor_name":"Injections, Intra-Articular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D008727","descriptor_name":"Methotrexate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012460","descriptor_name":"Sulfasalazine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D012460","descriptor_name":"Sulfasalazine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018501","descriptor_name":"Antirheumatic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1136/ard.2010.143347","doi":"https://doi.org/10.1136/ard.2010.143347","is_oa":false,"landing_page_url":"https://doi.org/10.1136/ard.2010.143347","pdf_url":null,"source":{"id":"https://openalex.org/S25650217","display_name":"Annals of the Rheumatic Diseases","issn_l":"0003-4967","issn":["0003-4967","1468-2060"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the Rheumatic Diseases","raw_type":"journal-article"},{"id":"pmid:21623000","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21623000","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of the rheumatic diseases","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:annrheumdis:ard.2010.143347v1","doi":null,"is_oa":false,"landing_page_url":"http://ard.bmj.com/cgi/content/short/ard.2010.143347v1","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1963703758","https://openalex.org/W1969936299","https://openalex.org/W1970000120","https://openalex.org/W1987733166","https://openalex.org/W1990594162","https://openalex.org/W1991605430","https://openalex.org/W2000654246","https://openalex.org/W2015515502","https://openalex.org/W2024691000","https://openalex.org/W2024860303","https://openalex.org/W2037646160","https://openalex.org/W2038089371","https://openalex.org/W2043306063","https://openalex.org/W2044668285","https://openalex.org/W2045091654","https://openalex.org/W2054242480","https://openalex.org/W2070021262","https://openalex.org/W2073700972","https://openalex.org/W2080638211","https://openalex.org/W2087402257","https://openalex.org/W2100982501","https://openalex.org/W2101040039","https://openalex.org/W2126378300","https://openalex.org/W2126989429","https://openalex.org/W2134389576","https://openalex.org/W2156996668","https://openalex.org/W2158299272","https://openalex.org/W2164570942","https://openalex.org/W2166909692","https://openalex.org/W2221264044","https://openalex.org/W2312982528","https://openalex.org/W2342174771","https://openalex.org/W6683294396","https://openalex.org/W6688631880"],"related_works":["https://openalex.org/W3120318880","https://openalex.org/W38685774","https://openalex.org/W2014383245","https://openalex.org/W2980974815","https://openalex.org/W2808656917","https://openalex.org/W1987733166","https://openalex.org/W45922203","https://openalex.org/W2280247619","https://openalex.org/W4323544556","https://openalex.org/W2909736393"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":18},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":20},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":13},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":21},{"year":2013,"cited_by_count":20},{"year":2012,"cited_by_count":13}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}