{"id":"https://openalex.org/W2156199232","doi":"https://doi.org/10.1016/s0360-3016(01)01809-0","title":"THE time course of radiation therapy-induced reductions in regional perfusion: a prospective study with >5 years of follow-up","display_name":"THE time course of radiation therapy-induced reductions in regional perfusion: a prospective study with >5 years of follow-up","publication_year":2002,"publication_date":"2002-01-01","ids":{"openalex":"https://openalex.org/W2156199232","doi":"https://doi.org/10.1016/s0360-3016(01)01809-0","mag":"2156199232","pmid":"https://pubmed.ncbi.nlm.nih.gov/11777622"},"language":"en","primary_location":{"id":"doi:10.1016/s0360-3016(01)01809-0","doi":"https://doi.org/10.1016/s0360-3016(01)01809-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0360-3016(01)01809-0","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041679160","display_name":"Roxanne T Woel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roxanne T Woel","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA","institution_ids":["https://openalex.org/I4210126298"]},{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052731624","display_name":"Michael T. Munley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael T Munley","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000206324","display_name":"Donna R. Hollis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donna Hollis","raw_affiliation_strings":["Comprehensive Cancer Center, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042776688","display_name":"Ming Fan","orcid":"https://orcid.org/0000-0001-8676-2716","observed_orcids":["https://orcid.org/0000-0001-8676-2716"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ming Fan","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110083477","display_name":"Gunilla C. Bentel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gunilla Bentel","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069874449","display_name":"Mitchell Steven Anscher","orcid":"https://orcid.org/0000-0003-4480-111X","observed_orcids":["https://orcid.org/0000-0003-4480-111X"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell S Anscher","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009275122","display_name":"Timothy D. Shafman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Shafman","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111832010","display_name":"R. Edward Coleman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.Edward Coleman","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011314848","display_name":"R.J. Jaszczak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald J Jaszczak","raw_affiliation_strings":["Department of Radiology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085651347","display_name":"Lawrence Bruce Marks","orcid":"https://orcid.org/0000-0001-8832-3303","observed_orcids":["https://orcid.org/0000-0001-8832-3303"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lawrence B Marks","raw_affiliation_strings":["Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5085651347"],"corresponding_institution_ids":["https://openalex.org/I4210126298"],"apc_list":{"value":4130,"currency":"USD","value_usd":4130},"apc_paid":null,"fwci":3.8965,"has_fulltext":false,"cited_by_count":70,"citation_normalized_percentile":{"value":0.93707538,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"52","issue":"1","first_page":"58","last_page":"67"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.7333999872207642,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.7333999872207642,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.15199999511241913,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.07169999927282333,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiation-induced-lung-injury","display_name":"radiation-induced lung injury","score":0.9290000200271606},{"id":"https://openalex.org/keywords/regional-lung-perfusion","display_name":"regional lung perfusion","score":0.8180000185966492},{"id":"https://openalex.org/keywords/radiation-dose-response","display_name":"radiation dose-response","score":0.5139999985694885},{"id":"https://openalex.org/keywords/radiation-dose-mapping","display_name":"radiation dose mapping","score":0.39500001072883606},{"id":"https://openalex.org/keywords/long-term-follow-up","display_name":"long-term follow-up","score":0.5979999899864197},{"id":"https://openalex.org/keywords/radiation-pneumonitis","display_name":"radiation pneumonitis","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.8639187812805176},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8096784949302673},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.6332036256790161},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5261449813842773},{"id":"https://openalex.org/C2780441642","wikidata":"https://www.wikidata.org/wiki/Q849737","display_name":"Single-photon emission computed tomography","level":2,"score":0.5245585441589355},{"id":"https://openalex.org/C135691158","wikidata":"https://www.wikidata.org/wiki/Q7168308","display_name":"Perfusion scanning","level":3,"score":0.46254464983940125},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.4421537518501282},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4056777358055115},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2214851677417755}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004307","descriptor_name":"Dose-Response Relationship, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D011832","descriptor_name":"Radiation Injuries","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015899","descriptor_name":"Tomography, Emission-Computed, Single-Photon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0360-3016(01)01809-0","doi":"https://doi.org/10.1016/s0360-3016(01)01809-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0360-3016(01)01809-0","pdf_url":null,"source":{"id":"https://openalex.org/S110533041","display_name":"International Journal of Radiation Oncology*Biology*Physics","issn_l":"0360-3016","issn":["0360-3016","1879-355X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Radiation Oncology*Biology*Physics","raw_type":"journal-article"},{"id":"pmid:11777622","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11777622","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of radiation oncology, biology, physics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.6399999856948853,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1352378877","display_name":"IN VIVO RADIONUCLIDE QUANTITATION USING EMISSION CT","funder_award_id":"5r01ca033541-19","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2077613919","display_name":null,"funder_award_id":"R01 CA33541","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G378073306","display_name":"RADIATION INDUCED WHOLE &REGIONAL LUNG INJURY IN HUMANS","funder_award_id":"R29CA069579","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8885279342","display_name":"Breast Cancer Imaging Using Non-Parallel Beam SPECT","funder_award_id":"R01CA076006","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1892952587","https://openalex.org/W1907802084","https://openalex.org/W1964624837","https://openalex.org/W1969179546","https://openalex.org/W1973277978","https://openalex.org/W1976732060","https://openalex.org/W1979772891","https://openalex.org/W1988245407","https://openalex.org/W1992893455","https://openalex.org/W1993858850","https://openalex.org/W1996611571","https://openalex.org/W1997679487","https://openalex.org/W2002207094","https://openalex.org/W2003360253","https://openalex.org/W2003374912","https://openalex.org/W2006693926","https://openalex.org/W2008184169","https://openalex.org/W2008192423","https://openalex.org/W2010208276","https://openalex.org/W2013586245","https://openalex.org/W2019260174","https://openalex.org/W2022376122","https://openalex.org/W2028153339","https://openalex.org/W2028473040","https://openalex.org/W2030819118","https://openalex.org/W2031002044","https://openalex.org/W2032142535","https://openalex.org/W2033366141","https://openalex.org/W2035980415","https://openalex.org/W2042917909","https://openalex.org/W2058007426","https://openalex.org/W2061076725","https://openalex.org/W2061833586","https://openalex.org/W2069247302","https://openalex.org/W2080416210","https://openalex.org/W2084041928","https://openalex.org/W2096687176","https://openalex.org/W2113775428","https://openalex.org/W2115394956","https://openalex.org/W2119020593","https://openalex.org/W2136845661","https://openalex.org/W2139807361","https://openalex.org/W2147178255","https://openalex.org/W2166000668","https://openalex.org/W2166988903","https://openalex.org/W2201703527","https://openalex.org/W2268085214","https://openalex.org/W2461296602"],"related_works":["https://openalex.org/W2067926940","https://openalex.org/W4252256125","https://openalex.org/W4255385977","https://openalex.org/W2002207094","https://openalex.org/W1478153759","https://openalex.org/W2128308633","https://openalex.org/W2772588643","https://openalex.org/W2079014931","https://openalex.org/W2139807361","https://openalex.org/W1034696148"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}