{"id":"https://openalex.org/W2156097553","doi":"https://doi.org/10.1073/pnas.160276997","title":"Altered expression of expansin modulates leaf growth and pedicel abscission in Arabidopsis thaliana","display_name":"Altered expression of expansin modulates leaf growth and pedicel abscission in Arabidopsis thaliana","publication_year":2000,"publication_date":"2000-08-08","ids":{"openalex":"https://openalex.org/W2156097553","doi":"https://doi.org/10.1073/pnas.160276997","mag":"2156097553","pmid":"https://pubmed.ncbi.nlm.nih.gov/10931949","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/16942"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.160276997","doi":"https://doi.org/10.1073/pnas.160276997","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.160276997","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC16942","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048256742","display_name":"Hyung\u2010Taeg Cho","orcid":"https://orcid.org/0000-0003-1743-3403","observed_orcids":["https://orcid.org/0000-0003-1743-3403"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hyung-Taeg Cho","raw_affiliation_strings":["Department of Biology, 208 Mueller Laboratory, Pennsylvania State University, University Park, PA 16802"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, 208 Mueller Laboratory, Pennsylvania State University, University Park, PA 16802","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003077680","display_name":"Daniel J. Cosgrove","orcid":"https://orcid.org/0000-0002-4020-5786","observed_orcids":["https://orcid.org/0000-0002-4020-5786"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel J. Cosgrove","raw_affiliation_strings":["Department of Biology, 208 Mueller Laboratory, Pennsylvania State University, University Park, PA 16802"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, 208 Mueller Laboratory, Pennsylvania State University, University Park, PA 16802","institution_ids":["https://openalex.org/I130769515"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I130769515"],"apc_list":null,"apc_paid":null,"fwci":22.7394,"has_fulltext":false,"cited_by_count":486,"citation_normalized_percentile":{"value":0.99503097,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"97","issue":"17","first_page":"9783","last_page":"9788"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.5835000276565552,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.5835000276565552,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10869","display_name":"Polysaccharides and Plant Cell Walls","score":0.3889000117778778,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14365","display_name":"Leaf Properties and Growth Measurement","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/expansin","display_name":"expansin","score":0.9100000262260437},{"id":"https://openalex.org/keywords/cell-wall-loosening","display_name":"cell wall loosening","score":0.7580000162124634},{"id":"https://openalex.org/keywords/leaf-growth","display_name":"leaf growth","score":0.9549999833106995},{"id":"https://openalex.org/keywords/leaf-morphology","display_name":"leaf morphology","score":0.7710000276565552},{"id":"https://openalex.org/keywords/antisense-transgenic-plants","display_name":"antisense transgenic plants","score":0.7049999833106995},{"id":"https://openalex.org/keywords/cell-wall-extensibility","display_name":"cell wall extensibility","score":0.7860000133514404},{"id":"https://openalex.org/keywords/organ-size-control","display_name":"organ size control","score":0.7409999966621399},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.9679999947547913}],"concepts":[{"id":"https://openalex.org/C99705001","wikidata":"https://www.wikidata.org/wiki/Q333666","display_name":"Abscission","level":2,"score":0.938956081867218},{"id":"https://openalex.org/C2778279081","wikidata":"https://www.wikidata.org/wiki/Q24738908","display_name":"Expansin","level":4,"score":0.9130697846412659},{"id":"https://openalex.org/C2779513598","wikidata":"https://www.wikidata.org/wiki/Q1206719","display_name":"Petiole (insect anatomy)","level":3,"score":0.8665624856948853},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7860318422317505},{"id":"https://openalex.org/C184458455","wikidata":"https://www.wikidata.org/wiki/Q1713537","display_name":"Pedicel","level":2,"score":0.7644845247268677},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6925963163375854},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.6703166365623474},{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.6213979721069336},{"id":"https://openalex.org/C125235067","wikidata":"https://www.wikidata.org/wiki/Q128700","display_name":"Cell wall","level":2,"score":0.6146492958068848},{"id":"https://openalex.org/C143141573","wikidata":"https://www.wikidata.org/wiki/Q7450971","display_name":"Sense (electronics)","level":2,"score":0.49164682626724243},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.4156864285469055},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.3187211751937866},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1630573570728302},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15066656470298767},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.10966533422470093},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.07407054305076599},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C2780653484","wikidata":"https://www.wikidata.org/wiki/Q22651","display_name":"Hymenoptera","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D002452","descriptor_name":"Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002473","descriptor_name":"Cell Wall","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010940","descriptor_name":"Plant Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014170","descriptor_name":"Transformation, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016372","descriptor_name":"RNA, Antisense","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D018515","descriptor_name":"Plant Leaves","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019076","descriptor_name":"Transgenes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048429","descriptor_name":"Cell Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.160276997","doi":"https://doi.org/10.1073/pnas.160276997","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.160276997","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:188532","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC16942","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:16942","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/16942","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},{"id":"pmid:10931949","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10931949","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:188532","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC16942","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W305575125","https://openalex.org/W1569955072","https://openalex.org/W1582301784","https://openalex.org/W1795138854","https://openalex.org/W1861748645","https://openalex.org/W1967592481","https://openalex.org/W1982579250","https://openalex.org/W1986161799","https://openalex.org/W2006183513","https://openalex.org/W2015121773","https://openalex.org/W2019444031","https://openalex.org/W2021443242","https://openalex.org/W2040612116","https://openalex.org/W2076042370","https://openalex.org/W2088095134","https://openalex.org/W2098155518","https://openalex.org/W2105302235","https://openalex.org/W2113936379","https://openalex.org/W2121971234","https://openalex.org/W2128607062","https://openalex.org/W2139053374","https://openalex.org/W2148663332","https://openalex.org/W2159080918","https://openalex.org/W2164879574","https://openalex.org/W2170473057","https://openalex.org/W4388384199"],"related_works":["https://openalex.org/W1971005597","https://openalex.org/W2145609319","https://openalex.org/W2096192175","https://openalex.org/W7098207905","https://openalex.org/W2359905587","https://openalex.org/W2587254674","https://openalex.org/W152582411","https://openalex.org/W2130862099","https://openalex.org/W1540606796","https://openalex.org/W2033329274"],"abstract_inverted_index":{"Expansins":[0],"are":[1],"cell-wall-loosening":[2,157],"proteins":[3],"that":[4,152,161,167],"induce":[5],"stress":[6],"relaxation":[7],"and":[8,31,38,50,63,82,85,101,120,159,174],"extension":[9],"of":[10,43,53,67,79,129,170],"plant":[11],"cell":[12,20,103],"walls.":[13],"To":[14],"evaluate":[15],"their":[16,102],"hypothesized":[17],"role":[18],"in":[19,28,36,59,109,139,144],"growth,":[21],"we":[22],"genetically":[23],"manipulated":[24],"expansin":[25],"gene":[26],"expression":[27],"Arabidopsis":[29],"thaliana":[30],"assessed":[32],"the":[33,60,65,68,127,130,150],"consequent":[34],"changes":[35],"growth":[37],"cell-wall":[39],"properties.":[40],"Various":[41],"combinations":[42],"promoters":[44],"were":[45,97,105],"used":[46],"to":[47],"drive":[48],"antisense":[49,73,95,145],"sense":[51,140],"sequences":[52],"AtEXP10,":[54],"which":[55],"is":[56,134],"maximally":[57],"expressed":[58],"growing":[61],"leaf":[62,83,90,118],"at":[64,126],"base":[66,128],"pedicel.":[69],"Compared":[70],"with":[71],"controls,":[72],"lines":[74],"had":[75,113],"smaller":[76,98],"rosettes":[77],"because":[78],"shorter":[80],"petioles":[81],"blades":[84],"often":[86],"acquired":[87],"a":[88],"twisted":[89],"morphology.":[91],"Petiole":[92],"cells":[93,122],"from":[94],"plants":[96,112,141],"than":[99,123],"controls":[100],"walls":[104],"significantly":[106],"less":[107],"extensible":[108],"vitro.":[110],"Sense":[111],"slightly":[114],"longer":[115],"petioles,":[116],"larger":[117,121],"blades,":[119],"controls.":[124],"Abscission":[125],"pedicel,":[131],"where":[132],"AtEXP10":[133],"endogenously":[135,155],"expressed,":[136],"was":[137],"enhanced":[138],"but":[142],"reduced":[143],"lines.":[146],"These":[147],"results":[148],"support":[149],"concept":[151],"expansins":[153,162],"function":[154],"as":[156],"agents":[158],"indicate":[160],"have":[163],"versatile":[164],"developmental":[165],"roles":[166],"include":[168],"control":[169],"organ":[171],"size,":[172],"morphology,":[173],"abscission.":[175]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":19},{"year":2023,"cited_by_count":16},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":17},{"year":2017,"cited_by_count":28},{"year":2016,"cited_by_count":20},{"year":2015,"cited_by_count":22},{"year":2014,"cited_by_count":28},{"year":2013,"cited_by_count":24},{"year":2012,"cited_by_count":27}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}