{"id":"https://openalex.org/W2155882004","doi":"https://doi.org/10.1093/infdis/140.1.119","title":"Inhibition by Polyanions of Adherence by Kanagawa-Positive Vibrio parahaemolyticus: A Physicochemical Effect","display_name":"Inhibition by Polyanions of Adherence by Kanagawa-Positive Vibrio parahaemolyticus: A Physicochemical Effect","publication_year":1979,"publication_date":"1979-07-01","ids":{"openalex":"https://openalex.org/W2155882004","doi":"https://doi.org/10.1093/infdis/140.1.119","mag":"2155882004","pmid":"https://pubmed.ncbi.nlm.nih.gov/458197"},"language":"en","primary_location":{"id":"doi:10.1093/infdis/140.1.119","doi":"https://doi.org/10.1093/infdis/140.1.119","is_oa":false,"landing_page_url":"https://doi.org/10.1093/infdis/140.1.119","pdf_url":null,"source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041841702","display_name":"Mary M. Carruthers","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"M. M. Carruthers","raw_affiliation_strings":["Departments of Medicine, Biochemistry, and Otolaryngology and Maxillofacial Surgery, Northwestern University Medical School, Chicago, Illinois","Medical Service, Veterans Administration Lakeside Medical Center, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, Biochemistry, and Otolaryngology and Maxillofacial Surgery, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Medical Service, Veterans Administration Lakeside Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"last","author":{"id":null,"display_name":"B. Anderson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]},{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Anderson","raw_affiliation_strings":["Departments of Medicine, Biochemistry, and Otolaryngology and Maxillofacial Surgery, Northwestern University Medical School, Chicago, Illinois","Medical Service, Veterans Administration Lakeside Medical Center, Chicago, Illinois"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Medicine, Biochemistry, and Otolaryngology and Maxillofacial Surgery, Northwestern University Medical School, Chicago, Illinois","institution_ids":["https://openalex.org/I111979921"]},{"raw_affiliation_string":"Medical Service, Veterans Administration Lakeside Medical Center, Chicago, Illinois","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5041841702"],"corresponding_institution_ids":["https://openalex.org/I111979921","https://openalex.org/I1322918889","https://openalex.org/I2799886695"],"apc_list":{"value":4763,"currency":"USD","value_usd":4763},"apc_paid":null,"fwci":1.545,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.82348178,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"140","issue":"1","first_page":"119","last_page":"122"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11684","display_name":"Vibrio bacteria research studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11684","display_name":"Vibrio bacteria research studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10943","display_name":"Escherichia coli research studies","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vibrio-parahaemolyticus","display_name":"Vibrio parahaemolyticus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/bacterial-adhesion","display_name":"bacterial adhesion","score":0.9629999995231628},{"id":"https://openalex.org/keywords/polyanions","display_name":"polyanions","score":0.7870000004768372},{"id":"https://openalex.org/keywords/chondroitin-sulfate","display_name":"chondroitin sulfate","score":0.8740000128746033},{"id":"https://openalex.org/keywords/surface-charge","display_name":"surface charge","score":0.7829999923706055},{"id":"https://openalex.org/keywords/glycoproteins","display_name":"glycoproteins","score":0.8759999871253967},{"id":"https://openalex.org/keywords/intestinal-epithelial-cells","display_name":"intestinal epithelial cells","score":0.7879999876022339},{"id":"https://openalex.org/keywords/calcium","display_name":"calcium","score":0.460999995470047}],"concepts":[{"id":"https://openalex.org/C2776575720","wikidata":"https://www.wikidata.org/wiki/Q134280","display_name":"Vibrio parahaemolyticus","level":3,"score":0.9666329026222229},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5873815417289734},{"id":"https://openalex.org/C2780358262","wikidata":"https://www.wikidata.org/wiki/Q1540423","display_name":"Surface charge","level":2,"score":0.48564210534095764},{"id":"https://openalex.org/C2779553658","wikidata":"https://www.wikidata.org/wiki/Q408014","display_name":"Chondroitin sulfate","level":3,"score":0.47581392526626587},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46514737606048584},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35113048553466797},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3403385281562805},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28410327434539795},{"id":"https://openalex.org/C153074725","wikidata":"https://www.wikidata.org/wiki/Q407553","display_name":"Glycosaminoglycan","level":2,"score":0.2648731768131256},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000268","descriptor_name":"Adhesiveness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000838","descriptor_name":"Anions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D014736","descriptor_name":"Vibrio parahaemolyticus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/infdis/140.1.119","doi":"https://doi.org/10.1093/infdis/140.1.119","is_oa":false,"landing_page_url":"https://doi.org/10.1093/infdis/140.1.119","pdf_url":null,"source":{"id":"https://openalex.org/S54542293","display_name":"The Journal of Infectious Diseases","issn_l":"0022-1899","issn":["0022-1899","1537-6613"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:458197","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/458197","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of infectious diseases","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1027.4771","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1027.4771","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jid.oxfordjournals.org/content/140/1/119.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W189260165","https://openalex.org/W1606146524","https://openalex.org/W1947850442","https://openalex.org/W2005291300","https://openalex.org/W2030326481","https://openalex.org/W2091862122","https://openalex.org/W2095742095","https://openalex.org/W2166582167","https://openalex.org/W2290575488","https://openalex.org/W2329661269","https://openalex.org/W2545691147"],"related_works":["https://openalex.org/W2030348371","https://openalex.org/W2329661269","https://openalex.org/W2047037127","https://openalex.org/W2059878316","https://openalex.org/W1571882860","https://openalex.org/W1955681135","https://openalex.org/W2152045217","https://openalex.org/W2037651313","https://openalex.org/W1746504369","https://openalex.org/W2903641388"],"abstract_inverted_index":{"Rapid":[0],"adherence":[1,74,107,121],"of":[2,24,43,52,67,73,85,91,106,111,117,128,132,139,145,149],"Kanagawa-positive":[3],"Vibrio":[4],"parahaemolyticus":[5,124],"to":[6,35,102],"human":[7],"fetal":[8],"intestinal":[9],"cells":[10],"has":[11],"been":[12],"demonstrated":[13],"in":[14,54,60,88,97,142,147],"monolayer":[15],"cultures.":[16],"In":[17],"this":[18,37,89],"study,":[19],"polyanionic":[20],"carbohydrates":[21],"and":[22,30,40,64,131],"glycoproteins":[23],"various":[25],"biochemical":[26],"compositions,":[27],"structural":[28],"configurations,":[29],"molecular":[31],"weights":[32],"were":[33,58],"found":[34],"inhibit":[36,49],"adherence.":[38,50,151],"Mono-":[39],"disaccharide":[41],"components":[42],"inhibitory":[44],"compounds":[45],"did":[46],"not":[47],"themselves":[48],"Levels":[51],"Ca++":[53],"the":[55,62,65,103,126,136,140,143],"test":[56],"mixture":[57],"similar":[59],"both":[61],"presence":[63],"absence":[66],"chondroitin":[68],"sulfate,":[69],"a":[70,82],"potent":[71],"inhibitor":[72],"by":[75,108,122],"V.":[76,112,123],"parahaemolyticus.":[77,113],"These":[78],"results,":[79],"which":[80],"demonstrate":[81],"major":[83],"effect":[84,116],"surface":[86,98,118,137],"charge":[87,99,119],"model":[90],"bacterial":[92,150],"adherence,":[93],"suggest":[94],"that":[95,134],"differences":[96],"may":[100],"contribute":[101],"varying":[104],"degrees":[105],"different":[109],"strains":[110],"This":[114],"striking":[115],"on":[120],"underscores":[125],"importance":[127],"experimental":[129],"conditions":[130],"substances":[133],"affect":[135],"potential":[138],"cell":[141],"interpretation":[144],"findings":[146],"models":[148]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}