{"id":"https://openalex.org/W2155773585","doi":"https://doi.org/10.1371/journal.pcbi.1002182","title":"Barriers to Diffusion in Dendrites and Estimation of Calcium Spread Following Synaptic Inputs","display_name":"Barriers to Diffusion in Dendrites and Estimation of Calcium Spread Following Synaptic Inputs","publication_year":2011,"publication_date":"2011-10-13","ids":{"openalex":"https://openalex.org/W2155773585","doi":"https://doi.org/10.1371/journal.pcbi.1002182","mag":"2155773585","pmid":"https://pubmed.ncbi.nlm.nih.gov/22022241","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3192802"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pcbi.1002182","doi":"https://doi.org/10.1371/journal.pcbi.1002182","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002182","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002182&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","ccf-b","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002182&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003236640","display_name":"Armin Biess","orcid":"https://orcid.org/0000-0002-0087-3675","observed_orcids":["https://orcid.org/0000-0002-0087-3675"]},"institutions":[{"id":"https://openalex.org/I4210087171","display_name":"Bernstein Center for Computational Neuroscience G\u00f6ttingen","ror":"https://ror.org/003g6b432","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210087171","https://openalex.org/I4210092532"]},{"id":"https://openalex.org/I4210088711","display_name":"Max Planck Institute for Dynamics and Self-Organization","ror":"https://ror.org/0087djs12","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210088711"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Armin Biess","raw_affiliation_strings":["Bernstein Center for Computational Neuroscience, G\u00f6ttingen, Germany. armin@nld.ds.mpg.de","Bernstein Center for Computational Neuroscience, G\u00f6ttingen, Germany","Max-Planck-Institute for Dynamics and Self-Organization, G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bernstein Center for Computational Neuroscience, G\u00f6ttingen, Germany. armin@nld.ds.mpg.de","institution_ids":["https://openalex.org/I4210087171"]},{"raw_affiliation_string":"Bernstein Center for Computational Neuroscience, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210087171"]},{"raw_affiliation_string":"Max-Planck-Institute for Dynamics and Self-Organization, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I4210088711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082878227","display_name":"Eduard Korkotian","orcid":"https://orcid.org/0000-0001-5515-3387","observed_orcids":["https://orcid.org/0000-0001-5515-3387"]},"institutions":[{"id":"https://openalex.org/I53964585","display_name":"Weizmann Institute of Science","ror":"https://ror.org/0316ej306","country_code":"IL","type":"education","lineage":["https://openalex.org/I53964585"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Eduard Korkotian","raw_affiliation_strings":["Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel","institution_ids":["https://openalex.org/I53964585"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006152136","display_name":"David Holcman","orcid":"https://orcid.org/0000-0001-9854-5014","observed_orcids":["https://orcid.org/0000-0001-9854-5014"]},"institutions":[{"id":"https://openalex.org/I29607241","display_name":"\u00c9cole Normale Sup\u00e9rieure - PSL","ror":"https://ror.org/05a0dhs15","country_code":"FR","type":"other","lineage":["https://openalex.org/I2746051580","https://openalex.org/I29607241"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"David Holcman","raw_affiliation_strings":["Department of Computational Biology, Ecole Normale Sup\u00e9rieure, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, Ecole Normale Sup\u00e9rieure, Paris, France","institution_ids":["https://openalex.org/I29607241"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5003236640","https://openalex.org/A5006152136"],"corresponding_institution_ids":["https://openalex.org/I29607241","https://openalex.org/I4210087171","https://openalex.org/I4210088711"],"apc_list":{"value":3043,"currency":"USD","value_usd":3043},"apc_paid":{"value":3043,"currency":"USD","value_usd":3043},"fwci":0.9101,"has_fulltext":true,"cited_by_count":64,"citation_normalized_percentile":{"value":0.65699447,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":99},"biblio":{"volume":"7","issue":"10","first_page":"e1002182","last_page":"e1002182"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.5195000171661377,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.5195000171661377,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.11330000311136246,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10288","display_name":"Fractional Differential Equations Solutions","score":0.06019999831914902,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macromolecular-crowding","display_name":"macromolecular crowding","score":0.9549999833106995},{"id":"https://openalex.org/keywords/diffusion-barrier","display_name":"diffusion barrier","score":0.9359999895095825},{"id":"https://openalex.org/keywords/dendrites","display_name":"dendrites","score":0.6650000214576721},{"id":"https://openalex.org/keywords/dendritic-spines","display_name":"dendritic spines","score":0.8420000076293945},{"id":"https://openalex.org/keywords/reaction-diffusion-systems","display_name":"reaction-diffusion systems","score":0.7590000033378601},{"id":"https://openalex.org/keywords/calcium-buffers","display_name":"calcium buffers","score":0.906000018119812},{"id":"https://openalex.org/keywords/calcium-pump","display_name":"calcium pump","score":0.7089999914169312},{"id":"https://openalex.org/keywords/synaptic-input","display_name":"synaptic input","score":0.7850000262260437},{"id":"https://openalex.org/keywords/microdomains","display_name":"microdomains","score":0.6119999885559082}],"concepts":[{"id":"https://openalex.org/C84248122","wikidata":"https://www.wikidata.org/wiki/Q5256671","display_name":"Dendrite (mathematics)","level":2,"score":0.806052565574646},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.6194370985031128},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5632505416870117},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.5570171475410461},{"id":"https://openalex.org/C174884520","wikidata":"https://www.wikidata.org/wiki/Q902079","display_name":"Dendritic spine","level":3,"score":0.5456850528717041},{"id":"https://openalex.org/C112401455","wikidata":"https://www.wikidata.org/wiki/Q178036","display_name":"Brownian motion","level":2,"score":0.5182964205741882},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.43720531463623047},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.41642439365386963},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3473721146583557},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.332996129989624},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3260188698768616},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1689494252204895},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1633162498474121},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.14382204413414001},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11060023307800293},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.09005999565124512},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003593","descriptor_name":"Cytoplasm","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003712","descriptor_name":"Dendrites","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":10,"locations":[{"id":"doi:10.1371/journal.pcbi.1002182","doi":"https://doi.org/10.1371/journal.pcbi.1002182","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002182","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002182&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","ccf-b","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2199894","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3192802","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:22022241","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22022241","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS computational biology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3192802","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3192802/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Comput Biol","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.290.1122","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.290.1122","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/13/e4/PLoS_Comput_Biol_2011_Oct_13_7(10)_e1002182.tar.gz","raw_type":"text"},{"id":"pmh:oai:RePEc:plo:pcbi00:1002182","doi":null,"is_oa":false,"landing_page_url":"https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1002182","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:adb13e7218884d03b20b58ae5639d3ac","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/adb13e7218884d03b20b58ae5639d3ac","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Computational Biology, Vol 7, Iss 10, p e1002182 (2011)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/132550","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Barriers_to_Diffusion_in_Dendrites_and_Estimation_of_Calcium_Spread_Following_Synaptic_Inputs/132550","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:goescholar:1/8438","doi":null,"is_oa":true,"landing_page_url":"http://resolver.sub.uni-goettingen.de/purl?gs-1/8438","pdf_url":null,"source":{"id":"https://openalex.org/S4306401634","display_name":"GoeScholar  The Publication Server of the Georg-August-Universit\u00e4t G\u00f6ttingen (Georg-August-Universit\u00e4t G\u00f6ttingen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210122495","host_organization_name":"Asklepios Klinik St. Georg","host_organization_lineage":["https://openalex.org/I4210122495"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journalArticle"},{"id":"pmh:oai:publications.goettingen-research-online.de:2/60568","doi":null,"is_oa":true,"landing_page_url":"https://resolver.sub.uni-goettingen.de/purl?gs-1/8438","pdf_url":null,"source":{"id":"https://openalex.org/S4306401634","display_name":"GoeScholar  The Publication Server of the Georg-August-Universit\u00e4t G\u00f6ttingen (Georg-August-Universit\u00e4t G\u00f6ttingen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210122495","host_organization_name":"Asklepios Klinik St. Georg","host_organization_lineage":["https://openalex.org/I4210122495"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"journal_article"}],"best_oa_location":{"id":"doi:10.1371/journal.pcbi.1002182","doi":"https://doi.org/10.1371/journal.pcbi.1002182","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pcbi.1002182","pdf_url":"https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002182&type=printable","source":{"id":"https://openalex.org/S86033158","display_name":"PLoS Computational Biology","issn_l":"1553-734X","issn":["1553-734X","1553-7358"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","ccf-b","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Computational Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1394443379","display_name":"Verbundprojekt: Bernstein-Zentrum f\u00fcr Computational Neuroscience, G\u00f6ttingen: Center for Adaptive and Neuronal Systems","funder_award_id":"01GQ0430","funder_id":"https://openalex.org/F4320321114","funder_display_name":"Bundesministerium f\u00fcr Bildung und Forschung"}],"funders":[{"id":"https://openalex.org/F4320321114","display_name":"Bundesministerium f\u00fcr Bildung und Forschung","ror":"https://ror.org/04pz7b180"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2155773585.pdf","grobid_xml":"https://content.openalex.org/works/W2155773585.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W1565036272","https://openalex.org/W1585209853","https://openalex.org/W1670760110","https://openalex.org/W1965202553","https://openalex.org/W1970948529","https://openalex.org/W1976776824","https://openalex.org/W1986606329","https://openalex.org/W1997105777","https://openalex.org/W1999486339","https://openalex.org/W1999855702","https://openalex.org/W2009777952","https://openalex.org/W2012392664","https://openalex.org/W2020445568","https://openalex.org/W2020907684","https://openalex.org/W2021036023","https://openalex.org/W2021285984","https://openalex.org/W2021578350","https://openalex.org/W2024685809","https://openalex.org/W2027275167","https://openalex.org/W2034447969","https://openalex.org/W2034728705","https://openalex.org/W2040060989","https://openalex.org/W2040207290","https://openalex.org/W2040336234","https://openalex.org/W2045696953","https://openalex.org/W2046320783","https://openalex.org/W2047898167","https://openalex.org/W2048212809","https://openalex.org/W2049294484","https://openalex.org/W2054071776","https://openalex.org/W2054950142","https://openalex.org/W2055862760","https://openalex.org/W2057496571","https://openalex.org/W2060872711","https://openalex.org/W2063161222","https://openalex.org/W2063625005","https://openalex.org/W2067790068","https://openalex.org/W2079641905","https://openalex.org/W2084058002","https://openalex.org/W2095352259","https://openalex.org/W2097711273","https://openalex.org/W2109950649","https://openalex.org/W2111155182","https://openalex.org/W2113966248","https://openalex.org/W2122328014","https://openalex.org/W2124812605","https://openalex.org/W2134937647","https://openalex.org/W2134972813","https://openalex.org/W2135998787","https://openalex.org/W2136626347","https://openalex.org/W2139125300","https://openalex.org/W2142847155","https://openalex.org/W2156458781","https://openalex.org/W2156961733","https://openalex.org/W2163126094","https://openalex.org/W2336411034","https://openalex.org/W4252161182","https://openalex.org/W6836052651"],"related_works":["https://openalex.org/W2322759966","https://openalex.org/W1554197593","https://openalex.org/W2057496571","https://openalex.org/W7096871664","https://openalex.org/W1514941454","https://openalex.org/W2063161222","https://openalex.org/W2069996697","https://openalex.org/W7096425910","https://openalex.org/W4392252275","https://openalex.org/W2090178344"],"abstract_inverted_index":{"The":[0],"motion":[1],"of":[2,30,71,135,184,187],"ions,":[3],"molecules":[4],"or":[5,165],"proteins":[6],"in":[7,37,57,75,80,89,112,129,177],"dendrites":[8,178],"is":[9,150,179],"restricted":[10],"by":[11,61,104,153,159],"cytoplasmic":[12,161],"obstacles":[13],"such":[14],"as":[15,96],"organelles,":[16],"microtubules":[17],"and":[18,79,139],"actin":[19],"network.":[20],"To":[21],"account":[22],"for":[23,145],"molecular":[24,94],"crowding,":[25,147,162],"we":[26,85,119,172],"study":[27],"the":[28,87,106,133,154,160,185],"effect":[29],"diffusion":[31,56,65,90],"barriers":[32],"on":[33,46],"local":[34],"calcium":[35,127,148,175],"spread":[36,128,176],"a":[38,43,47,53,58,62,76,81,113,121,130,188],"dendrite.":[39,117],"We":[40,100,142],"first":[41],"present":[42],"model":[44,116,126],"based":[45],"dimension":[48],"reduction":[49],"approach":[50,103],"to":[51,93,125,181],"approximate":[52],"three":[54],"dimensional":[55],"cylindrical":[59],"dendrite":[60,78,131],"one-dimensional":[63],"effective":[64],"process.":[66],"By":[67],"comparing":[68],"uncaging":[69,107],"experiments":[70,108],"an":[72],"inert":[73],"dye":[74],"spiny":[77],"thin":[82],"glass":[83],"tube,":[84],"quantify":[86],"change":[88],"constants":[91],"due":[92],"crowding":[95],"D(cyto)/D(water)":[97],"=":[98],"1/20.":[99],"validate":[101],"our":[102],"reconstructing":[105],"using":[109],"Brownian":[110],"simulations":[111],"realistic":[114],"3D":[115],"Finally,":[118],"construct":[120],"reduced":[122],"reaction-diffusion":[123],"equation":[124],"under":[132],"presence":[134],"additional":[136],"buffers,":[137],"pumps":[138],"synaptic":[140,166],"input.":[141],"find":[143],"that":[144,174],"moderate":[146],"dynamics":[149],"mainly":[151],"regulated":[152],"buffer":[155],"concentration,":[156],"but":[157],"not":[158],"dendritic":[163],"spines":[164],"inputs.":[167],"Following":[168],"high":[169],"frequency":[170],"stimulations,":[171],"predict":[173],"limited":[180],"small":[182],"microdomains":[183],"order":[186],"few":[189],"microns":[190],"(<5":[191],"\u03bcm).":[192]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}