{"id":"https://openalex.org/W2155689471","doi":"https://doi.org/10.1093/tropej/fmq080","title":"Acute Extrapyramidal Dysfunction in Two HIV-infected Children","display_name":"Acute Extrapyramidal Dysfunction in Two HIV-infected Children","publication_year":2010,"publication_date":"2010-09-13","ids":{"openalex":"https://openalex.org/W2155689471","doi":"https://doi.org/10.1093/tropej/fmq080","mag":"2155689471","pmid":"https://pubmed.ncbi.nlm.nih.gov/20837555"},"language":"en","primary_location":{"id":"doi:10.1093/tropej/fmq080","doi":"https://doi.org/10.1093/tropej/fmq080","is_oa":false,"landing_page_url":"https://doi.org/10.1093/tropej/fmq080","pdf_url":null,"source":{"id":"https://openalex.org/S138039823","display_name":"Journal of Tropical Pediatrics","issn_l":"0142-6338","issn":["0142-6338","1465-3664"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Tropical Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048084253","display_name":"Regan Solomons","orcid":"https://orcid.org/0000-0002-5607-8443","observed_orcids":["https://orcid.org/0000-0002-5607-8443"]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"R. Solomons","raw_affiliation_strings":["Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa. regan@sun.ac.za","Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa. regan@sun.ac.za","institution_ids":["https://openalex.org/I26092322"]},{"raw_affiliation_string":"Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa","institution_ids":["https://openalex.org/I26092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087727017","display_name":"Amy L. Slogrove","orcid":"https://orcid.org/0000-0002-8046-9268","observed_orcids":["https://orcid.org/0000-0002-8046-9268"]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"A. Slogrove","raw_affiliation_strings":["Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa","institution_ids":["https://openalex.org/I26092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113907669","display_name":"Johannes F Schoeman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"J. Schoeman","raw_affiliation_strings":["Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa","institution_ids":["https://openalex.org/I26092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108086208","display_name":"B. J. Marais","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"B. Marais","raw_affiliation_strings":["Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa","institution_ids":["https://openalex.org/I26092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027678141","display_name":"Gert Uves van Zyl","orcid":"https://orcid.org/0000-0003-3021-5101","observed_orcids":["https://orcid.org/0000-0003-3021-5101"]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"G. van Zyl","raw_affiliation_strings":["Department of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa","institution_ids":["https://openalex.org/I26092322"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055492737","display_name":"Jean Maritz","orcid":"https://orcid.org/0000-0001-5311-9134","observed_orcids":["https://orcid.org/0000-0001-5311-9134"]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"J. Maritz","raw_affiliation_strings":["Department of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa","institution_ids":["https://openalex.org/I26092322"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004940530","display_name":"Ronald van Toorn","orcid":"https://orcid.org/0000-0002-2689-065X","observed_orcids":["https://orcid.org/0000-0002-2689-065X"]},"institutions":[{"id":"https://openalex.org/I26092322","display_name":"Stellenbosch University","ror":"https://ror.org/05bk57929","country_code":"ZA","type":"education","lineage":["https://openalex.org/I26092322"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"R. van Toorn","raw_affiliation_strings":["Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa","institution_ids":["https://openalex.org/I26092322"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I26092322"],"apc_list":{"value":3250,"currency":"USD","value_usd":3250},"apc_paid":null,"fwci":0.1126,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.47383852,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"57","issue":"3","first_page":"227","last_page":"231"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.8086000084877014,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.8086000084877014,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13966","display_name":"Neurological and metabolic disorders","score":0.04899999871850014,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis","score":0.04450000077486038,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/extrapyramidal-disorders","display_name":"extrapyramidal disorders","score":0.8859999775886536},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.7139999866485596},{"id":"https://openalex.org/keywords/pediatric-hiv","display_name":"pediatric HIV","score":0.7760000228881836},{"id":"https://openalex.org/keywords/basal-ganglia","display_name":"basal ganglia","score":0.8489999771118164},{"id":"https://openalex.org/keywords/hiv-encephalopathy","display_name":"HIV encephalopathy","score":0.890999972820282},{"id":"https://openalex.org/keywords/movement-disorders","display_name":"movement disorders","score":0.7229999899864197},{"id":"https://openalex.org/keywords/opportunistic-infections","display_name":"opportunistic infections","score":0.7580000162124634},{"id":"https://openalex.org/keywords/immunocompetence","display_name":"immunocompetence","score":0.7319999933242798},{"id":"https://openalex.org/keywords/mri-findings","display_name":"MRI findings","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8668011426925659},{"id":"https://openalex.org/C2780725373","wikidata":"https://www.wikidata.org/wiki/Q4866181","display_name":"Basal ganglia disease","level":4,"score":0.6436898112297058},{"id":"https://openalex.org/C2778621155","wikidata":"https://www.wikidata.org/wiki/Q576349","display_name":"Encephalopathy","level":2,"score":0.5842850804328918},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5745446681976318},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5708115100860596},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.47764527797698975},{"id":"https://openalex.org/C2778187257","wikidata":"https://www.wikidata.org/wiki/Q464210","display_name":"Basal ganglia","level":3,"score":0.47152528166770935},{"id":"https://openalex.org/C2778261627","wikidata":"https://www.wikidata.org/wiki/Q2608695","display_name":"Movement disorders","level":3,"score":0.44934993982315063},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40611720085144043},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2606937289237976},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.24728524684906006},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.18109583854675293},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.16196873784065247},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.10075289011001587}],"mesh":[{"descriptor_ui":"D001480","descriptor_name":"Basal Ganglia Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D001480","descriptor_name":"Basal Ganglia Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003586","descriptor_name":"Cytomegalovirus Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003586","descriptor_name":"Cytomegalovirus Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D017088","descriptor_name":"AIDS-Related Opportunistic Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D017088","descriptor_name":"AIDS-Related Opportunistic Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D020820","descriptor_name":"Dyskinesias","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/tropej/fmq080","doi":"https://doi.org/10.1093/tropej/fmq080","is_oa":false,"landing_page_url":"https://doi.org/10.1093/tropej/fmq080","pdf_url":null,"source":{"id":"https://openalex.org/S138039823","display_name":"Journal of Tropical Pediatrics","issn_l":"0142-6338","issn":["0142-6338","1465-3664"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Tropical Pediatrics","raw_type":"journal-article"},{"id":"pmid:20837555","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20837555","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of tropical pediatrics","raw_type":"Case Reports"},{"id":"pmh:oai:scholar.sun.ac.za:10019.1/16657","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10019.1/16657","pdf_url":null,"source":{"id":"https://openalex.org/S4306400300","display_name":"SUNScholar (Stellenbosch University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I26092322","host_organization_name":"Stellenbosch University","host_organization_lineage":["https://openalex.org/I26092322"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1936351921","https://openalex.org/W2002456963","https://openalex.org/W2029573729","https://openalex.org/W2037986192","https://openalex.org/W2047369206","https://openalex.org/W2050314741","https://openalex.org/W2064519186","https://openalex.org/W2068169180","https://openalex.org/W2073144616","https://openalex.org/W2076405547","https://openalex.org/W2083262189","https://openalex.org/W2093683022","https://openalex.org/W2106759818","https://openalex.org/W2122986037","https://openalex.org/W2125225315","https://openalex.org/W2129285152","https://openalex.org/W2141510469","https://openalex.org/W2329328415","https://openalex.org/W2339922662","https://openalex.org/W2410969368","https://openalex.org/W2612016156"],"related_works":["https://openalex.org/W2073144616","https://openalex.org/W2199323405","https://openalex.org/W2065856568","https://openalex.org/W1966729482","https://openalex.org/W1969660639","https://openalex.org/W2421663882","https://openalex.org/W2154487680","https://openalex.org/W2025428592","https://openalex.org/W2155853887","https://openalex.org/W2008392044"],"abstract_inverted_index":{"Involvement":[0],"of":[1,21,55,71,75,80,83,97],"the":[2,46,69,92],"basal":[3,29],"ganglia":[4],"is":[5,38],"well":[6],"documented":[7],"in":[8,27,34,41,100],"children":[9,58,82],"with":[10,17,61],"human":[11],"immunodeficiency":[12],"virus":[13],"(HIV)":[14],"encephalopathy,":[15],"often":[16],"calcification.":[18],"High":[19],"concentrations":[20],"HIV":[22,78],"protein":[23],"have":[24],"been":[25],"detected":[26],"affected":[28],"ganglia,":[30],"although":[31],"extrapyramidal":[32,64],"dysfunction,":[33],"contrast":[35],"to":[36],"adults,":[37],"infrequently":[39],"encountered":[40],"HIV-infected":[42,57,84,101],"children.":[43,102],"We":[44],"describe":[45],"clinical":[47],"course,":[48],"magnetic":[49,87],"resonance":[50,88],"imaging":[51,89],"appearance":[52],"and":[53,86,94],"outcome":[54],"two":[56],"who":[59],"presented":[60],"acute":[62],"debilitating":[63],"dysfunction.":[65],"The":[66],"cases":[67],"highlight":[68],"importance":[70],"immune":[72],"competence,":[73],"co-existence":[74],"opportunistic":[76],"infections,":[77],"testing":[79],"all":[81],"mothers":[85],"when":[90],"assessing":[91],"severity":[93],"anticipating":[95],"outcomes":[96],"movement":[98],"disorders":[99]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}