{"id":"https://openalex.org/W2155166404","doi":"https://doi.org/10.1101/gr.111609.110","title":"Observation and prediction of recurrent human translocations mediated by NAHR between nonhomologous chromosomes","display_name":"Observation and prediction of recurrent human translocations mediated by NAHR between nonhomologous chromosomes","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2155166404","doi":"https://doi.org/10.1101/gr.111609.110","mag":"2155166404","pmid":"https://pubmed.ncbi.nlm.nih.gov/21205869","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3012924"},"language":"en","primary_location":{"id":"doi:10.1101/gr.111609.110","doi":"https://doi.org/10.1101/gr.111609.110","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gr.111609.110","pdf_url":"http://genome.cshlp.org/content/21/1/33.full.pdf","source":{"id":"https://openalex.org/S43092948","display_name":"Genome Research","issn_l":"1088-9051","issn":["1088-9051","1549-5469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Research","raw_type":"journal-article"},"volume":null,"type":"preprint","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://genome.cshlp.org/content/21/1/33.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076412646","display_name":"Zhishuo Ou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhishuo Ou","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075195054","display_name":"Pawe\u0142 Stankiewicz","orcid":"https://orcid.org/0000-0002-6456-7490","observed_orcids":["https://orcid.org/0000-0002-6456-7490"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pawe\u0142 Stankiewicz","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069965861","display_name":"Zhilian Xia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhilian Xia","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015070707","display_name":"Amy M. Breman","orcid":"https://orcid.org/0000-0003-0299-0100","observed_orcids":["https://orcid.org/0000-0003-0299-0100"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy M. Breman","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113571744","display_name":"Brian Dawson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian Dawson","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040134612","display_name":"Joanna Wiszniewska","orcid":"https://orcid.org/0000-0003-2970-8005","observed_orcids":["https://orcid.org/0000-0003-2970-8005"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanna Wiszniewska","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054681586","display_name":"Przemys\u0142aw Szafra\u0144ski","orcid":"https://orcid.org/0000-0002-3886-2971","observed_orcids":["https://orcid.org/0000-0002-3886-2971"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Przemyslaw Szafranski","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111782428","display_name":"M. Lance Cooper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Lance Cooper","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027288700","display_name":"Mitchell Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell Rao","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071790804","display_name":"Lina Shao","orcid":"https://orcid.org/0000-0002-6650-1698","observed_orcids":["https://orcid.org/0000-0002-6650-1698"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lina Shao","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003907612","display_name":"Sarah T. South","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah T. South","raw_affiliation_strings":["Departments of Pediatrics and Pathology, University of Utah, Salt Lake City, Utah 84112, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Pediatrics and Pathology, University of Utah, Salt Lake City, Utah 84112, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103413552","display_name":"Karlene B. Coleman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146983","display_name":"Children's Healthcare of Atlanta","ror":"https://ror.org/050fhx250","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146983"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karlene Coleman","raw_affiliation_strings":["Children's Healthcare of Atlanta, Atlanta, Georgia 30033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Healthcare of Atlanta, Atlanta, Georgia 30033, USA","institution_ids":["https://openalex.org/I4210146983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110014913","display_name":"Paul M. Fernhoff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146983","display_name":"Children's Healthcare of Atlanta","ror":"https://ror.org/050fhx250","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146983"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul M. Fernhoff","raw_affiliation_strings":["Children's Healthcare of Atlanta, Atlanta, Georgia 30033, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children's Healthcare of Atlanta, Atlanta, Georgia 30033, USA","institution_ids":["https://openalex.org/I4210146983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077290897","display_name":"Marcel J. Deray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146630","display_name":"Miami Children's Hospital","ror":"https://ror.org/048d1b238","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146630"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcel J. Deray","raw_affiliation_strings":["Department of Neurology, Miami Children's Hospital, Miami, Florida 33155, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Miami Children's Hospital, Miami, Florida 33155, USA","institution_ids":["https://openalex.org/I4210146630"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111653995","display_name":"Sally Shulman Rosengren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1302163369","display_name":"Hartford Hospital","ror":"https://ror.org/00gt5xe03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1302163369"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sally Rosengren","raw_affiliation_strings":["Hartford Hospital, Hartford, Connecticut 06102, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hartford Hospital, Hartford, Connecticut 06102, USA","institution_ids":["https://openalex.org/I1302163369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005773767","display_name":"Elizabeth R. Roeder","orcid":"https://orcid.org/0000-0002-8439-657X","observed_orcids":["https://orcid.org/0000-0002-8439-657X"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth R. Roeder","raw_affiliation_strings":["Department of Pediatrics, UTHSCSA, San Antonio, Texas 78229, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, UTHSCSA, San Antonio, Texas 78229, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063695357","display_name":"Victoria B. Enciso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victoria B. Enciso","raw_affiliation_strings":["Department of Pediatrics, UTHSCSA, San Antonio, Texas 78229, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, UTHSCSA, San Antonio, Texas 78229, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111716329","display_name":"A. Craig Chinault","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Craig Chinault","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102744432","display_name":"Ankita Patel","orcid":"https://orcid.org/0000-0002-7720-0663","observed_orcids":["https://orcid.org/0000-0002-7720-0663"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ankita Patel","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029812912","display_name":"Sung-Hae Lee Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sung-Hae L. Kang","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072387201","display_name":"Chad A. Shaw","orcid":"https://orcid.org/0000-0001-7267-5398","observed_orcids":["https://orcid.org/0000-0001-7267-5398"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chad A. Shaw","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000612576","display_name":"James R. Lupski","orcid":"https://orcid.org/0000-0001-9907-9246","observed_orcids":["https://orcid.org/0000-0001-9907-9246"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210147586","display_name":"Texas Children's Hospital","ror":"https://ror.org/05cz92x43","country_code":"US","type":"funder","lineage":["https://openalex.org/I4210147586"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James R. Lupski","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA","Texas Children's Hospital, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]},{"raw_affiliation_string":"Texas Children's Hospital, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I4210147586"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061084392","display_name":"Sau Wai Cheung","orcid":"https://orcid.org/0000-0002-3813-5256","observed_orcids":["https://orcid.org/0000-0002-3813-5256"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sau W. Cheung","raw_affiliation_strings":["Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA","institution_ids":["https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":97,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"21","issue":"1","first_page":"33","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.006500000134110451,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-allelic-homologous-recombination","display_name":"non-allelic homologous recombination","score":0.972000002861023},{"id":"https://openalex.org/keywords/breakpoint-mapping","display_name":"breakpoint mapping","score":0.5989999771118164},{"id":"https://openalex.org/keywords/chromosome-4","display_name":"chromosome 4","score":0.5400000214576721},{"id":"https://openalex.org/keywords/chromosome-8","display_name":"chromosome 8","score":0.8489999771118164},{"id":"https://openalex.org/keywords/chromosome-12","display_name":"chromosome 12","score":0.8730000257492065},{"id":"https://openalex.org/keywords/chromosome-11","display_name":"chromosome 11","score":0.8799999952316284}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9220671653747559},{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.7138455510139465},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.638076663017273},{"id":"https://openalex.org/C122917832","wikidata":"https://www.wikidata.org/wiki/Q2065945","display_name":"Non-homologous end joining","level":4,"score":0.4616504907608032},{"id":"https://openalex.org/C102744134","wikidata":"https://www.wikidata.org/wiki/Q22280388","display_name":"Homologous recombination","level":3,"score":0.376314640045166},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3519638180732727},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2432812750339508}],"mesh":[{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002880","descriptor_name":"Chromosomes, Human, Pair 11","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002894","descriptor_name":"Chromosomes, Human, Pair 4","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005190","descriptor_name":"Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011995","descriptor_name":"Recombination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014178","descriptor_name":"Translocation, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D017422","descriptor_name":"Sequence Analysis, DNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018035","descriptor_name":"Receptors, Odorant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019457","descriptor_name":"Chromosome Breakage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D025063","descriptor_name":"Chromosome Disorders","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025063","descriptor_name":"Chromosome Disorders","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D055028","descriptor_name":"Comparative Genomic Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056916","descriptor_name":"Segmental Duplications, Genomic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1101/gr.111609.110","doi":"https://doi.org/10.1101/gr.111609.110","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gr.111609.110","pdf_url":"http://genome.cshlp.org/content/21/1/33.full.pdf","source":{"id":"https://openalex.org/S43092948","display_name":"Genome Research","issn_l":"1088-9051","issn":["1088-9051","1549-5469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2034542","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3012924","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3012924","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3012924","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Res","raw_type":"Text"},{"id":"pmid:21205869","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21205869","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome research","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:genome:21/1/33","doi":null,"is_oa":false,"landing_page_url":"http://genome.cshlp.org/cgi/content/short/21/1/33","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1101/gr.111609.110","doi":"https://doi.org/10.1101/gr.111609.110","is_oa":true,"landing_page_url":"https://doi.org/10.1101/gr.111609.110","pdf_url":"http://genome.cshlp.org/content/21/1/33.full.pdf","source":{"id":"https://openalex.org/S43092948","display_name":"Genome Research","issn_l":"1088-9051","issn":["1088-9051","1549-5469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315909","host_organization_name":"Cold Spring Harbor Laboratory Press","host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Genome Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2544796598","display_name":"COMPLEX GENOMIC REARRANGEMENTS IN NEUROLOGICAL DISEASE","funder_award_id":"R01NS058529","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G6497260306","display_name":null,"funder_award_id":"NS058529","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G7057538999","display_name":"General Clinical Research Center","funder_award_id":"M01RR000188","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2155166404.pdf","grobid_xml":"https://content.openalex.org/works/W2155166404.grobid-xml"},"referenced_works_count":74,"referenced_works":["https://openalex.org/W161998828","https://openalex.org/W1482498530","https://openalex.org/W1495912443","https://openalex.org/W1512915155","https://openalex.org/W1577454886","https://openalex.org/W1963756058","https://openalex.org/W1965478935","https://openalex.org/W1967352352","https://openalex.org/W1969245300","https://openalex.org/W1970283686","https://openalex.org/W1975653746","https://openalex.org/W1977625458","https://openalex.org/W1981504013","https://openalex.org/W1982966806","https://openalex.org/W1986002337","https://openalex.org/W1987024037","https://openalex.org/W1987342312","https://openalex.org/W1991642156","https://openalex.org/W1996756110","https://openalex.org/W1997647094","https://openalex.org/W2000331614","https://openalex.org/W2000471643","https://openalex.org/W2005336569","https://openalex.org/W2006085234","https://openalex.org/W2019469673","https://openalex.org/W2021491947","https://openalex.org/W2021714239","https://openalex.org/W2025953092","https://openalex.org/W2035120673","https://openalex.org/W2035380874","https://openalex.org/W2037978113","https://openalex.org/W2042524059","https://openalex.org/W2044110911","https://openalex.org/W2045325156","https://openalex.org/W2047657819","https://openalex.org/W2049323804","https://openalex.org/W2052860512","https://openalex.org/W2056113180","https://openalex.org/W2058790676","https://openalex.org/W2064014152","https://openalex.org/W2074837973","https://openalex.org/W2076032878","https://openalex.org/W2077016335","https://openalex.org/W2081185524","https://openalex.org/W2081906057","https://openalex.org/W2084538804","https://openalex.org/W2086341955","https://openalex.org/W2089548634","https://openalex.org/W2090572207","https://openalex.org/W2098000677","https://openalex.org/W2098187463","https://openalex.org/W2098380802","https://openalex.org/W2101886165","https://openalex.org/W2102138832","https://openalex.org/W2106021702","https://openalex.org/W2106982327","https://openalex.org/W2110793364","https://openalex.org/W2115957572","https://openalex.org/W2125419309","https://openalex.org/W2130407782","https://openalex.org/W2136211437","https://openalex.org/W2140383855","https://openalex.org/W2140500959","https://openalex.org/W2141712044","https://openalex.org/W2142701631","https://openalex.org/W2146892790","https://openalex.org/W2147555564","https://openalex.org/W2151109134","https://openalex.org/W2151318268","https://openalex.org/W2152079029","https://openalex.org/W2153994884","https://openalex.org/W2156922030","https://openalex.org/W2161409513","https://openalex.org/W2612812586"],"related_works":["https://openalex.org/W7098826280","https://openalex.org/W1972453970","https://openalex.org/W1988437534","https://openalex.org/W2048749333","https://openalex.org/W161998828","https://openalex.org/W2115368313","https://openalex.org/W2064014152","https://openalex.org/W7056664601","https://openalex.org/W2058790676","https://openalex.org/W2167482501"],"abstract_inverted_index":{"Four":[0],"unrelated":[1],"families":[2],"with":[3],"the":[4,13,42,76,83,133,158,186],"same":[5],"unbalanced":[6],"translocation":[7,46,79,92,127,197],"der(4)t(4;11)(p16.2;p15.4)":[8],"were":[9,20,143],"analyzed.":[10],"Both":[11],"of":[12,44,54,86,135,152],"breakpoint":[14],"regions":[15],"in":[16,57,65,89,108,148,157],"4p16.2":[17],"and":[18,25,34,59,99,110,162,177,179],"11p15.4":[19],"narrowed":[21],"to":[22,47],"large":[23],"\u223c359-kb":[24],"\u223c215-kb":[26],"low-copy":[27],"repeat":[28],"(LCR)":[29],"clusters,":[30,69],"respectively,":[31],"by":[32,131],"aCGH":[33],"SNP":[35],"array":[36],"analyses.":[37],"DNA":[38,61],"sequencing":[39,132],"enabled":[40],"mapping":[41],"breakpoints":[43,134],"one":[45],"24":[48],"bp":[49,147],"within":[50,145],"interchromosomal":[51,87,102,124,183],"paralogous":[52,150],"LCRs":[53,88],"\u223c130":[55],"kb":[56,107],"length":[58],"94.7%":[60],"sequence":[62,113,154],"identity":[63,114,155],"located":[64,156],"olfactory":[66],"receptor":[67],"gene":[68],"indicating":[70],"nonallelic":[71],"homologous":[72],"recombination":[73],"(NAHR)":[74],"as":[75],"mechanism":[77],"for":[78,123],"formation.":[80],"To":[81],"investigate":[82],"potential":[84],"involvement":[85],"recurrent":[90,137,173],"chromosomal":[91,119],"formation,":[93],"we":[94,190],"performed":[95],"computational":[96],"genome-wide":[97,195],"analyses":[98],"identified":[100],"1143":[101],"LCR":[103,166],"substrate":[104],"pairs,":[105],">5":[106],"size":[109],"sharing":[111],">94%":[112],"that":[115,170],"can":[116],"potentially":[117,180],"mediate":[118],"translocations.":[120],"Additional":[121],"evidence":[122],"NAHR":[125,141,171],"mediated":[126],"formation":[128],"was":[129],"provided":[130],"another":[136],"translocation,":[138],"der(8)t(8;12)(p23.1;p13.31).":[139],"The":[140],"sites":[142],"mapped":[144],"55":[146],"\u223c7.8-kb":[149],"subunits":[151],"95.3%":[153],"\u223c579-kb":[159],"(chr":[160,164],"8)":[161],"\u223c287-kb":[163],"12)":[165],"clusters.":[167],"We":[168],"demonstrate":[169],"mediates":[172],"constitutional":[174],"translocations":[175,184],"t(4;11)":[176],"t(8;12)":[178],"many":[181],"other":[182],"throughout":[185],"human":[187],"genome.":[188],"Furthermore,":[189],"provide":[191],"a":[192],"computationally":[193],"determined":[194],"\"recurrent":[196],"map.\"":[198]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":12}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
