{"id":"https://openalex.org/W2154802806","doi":null,"title":"Studies on the role of Gata3 during development","display_name":"Studies on the role of Gata3 during development","publication_year":2008,"publication_date":"2008-02-06","ids":{"openalex":"https://openalex.org/W2154802806","mag":"2154802806"},"language":"en","primary_location":{"id":"pmh:eur:oai:pure.eur.nl:publications/f6a41a29-a983-461b-848e-22d6c5116fa5","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/f6a41a29-a983-461b-848e-22d6c5116fa5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pure.eur.nl/en/publications/f6a41a29-a983-461b-848e-22d6c5116fa5","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049993977","display_name":"Dorota Kurek","orcid":"https://orcid.org/0000-0002-7168-8944","observed_orcids":["https://orcid.org/0000-0002-7168-8944"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Dorota Kurek","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7168-8944","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5049993977"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.4377000033855438,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.4377000033855438,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.27810001373291016,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":0.1031000018119812,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gata3","display_name":"GATA3","score":0.9890000224113464},{"id":"https://openalex.org/keywords/transcription-factors","display_name":"transcription factors","score":0.972000002861023},{"id":"https://openalex.org/keywords/tissue-specific-expression","display_name":"tissue-specific gene expression","score":0.8489999771118164},{"id":"https://openalex.org/keywords/embryonic-development","display_name":"embryonic development","score":0.7649999856948853},{"id":"https://openalex.org/keywords/skin-development","display_name":"skin development","score":0.9430000185966492},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5099999904632568},{"id":"https://openalex.org/keywords/enhancers","display_name":"enhancers","score":0.5709999799728394},{"id":"https://openalex.org/keywords/promoter","display_name":"promoter","score":0.6190000176429749},{"id":"https://openalex.org/keywords/cell-differentiation","display_name":"cell differentiation","score":0.367000013589859}],"concepts":[{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.860400915145874},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.7635236978530884},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6852902173995972},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6700828671455383},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5826380848884583},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.5463871955871582},{"id":"https://openalex.org/C76753757","wikidata":"https://www.wikidata.org/wiki/Q3825657","display_name":"E-box","level":5,"score":0.4916256070137024},{"id":"https://openalex.org/C102037460","wikidata":"https://www.wikidata.org/wiki/Q18025464","display_name":"GATA3","level":4,"score":0.4823574423789978},{"id":"https://openalex.org/C137858568","wikidata":"https://www.wikidata.org/wiki/Q7239","display_name":"Organism","level":2,"score":0.4530945420265198},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.45102471113204956},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.4306446313858032},{"id":"https://openalex.org/C146027311","wikidata":"https://www.wikidata.org/wiki/Q18031820","display_name":"TAF2","level":5,"score":0.41744449734687805},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.41505536437034607},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39624840021133423},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:eur:oai:pure.eur.nl:publications/f6a41a29-a983-461b-848e-22d6c5116fa5","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/f6a41a29-a983-461b-848e-22d6c5116fa5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:eur:oai:repub.eur.nl:11127","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/11127","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:oai:repub.eur.nl:11127","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/11127","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:2154802806","doi":null,"is_oa":false,"landing_page_url":"https://repub.eur.nl/pub/11127/080206_Kurek,%20Dorota%20Malgorzata.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:eur:oai:pure.eur.nl:publications/f6a41a29-a983-461b-848e-22d6c5116fa5","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/f6a41a29-a983-461b-848e-22d6c5116fa5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":270,"referenced_works":["https://openalex.org/W191074764","https://openalex.org/W1429171507","https://openalex.org/W1484675846","https://openalex.org/W1486415662","https://openalex.org/W1488598317","https://openalex.org/W1509968819","https://openalex.org/W1518253765","https://openalex.org/W1532399084","https://openalex.org/W1534987406","https://openalex.org/W1544564404","https://openalex.org/W1558443277","https://openalex.org/W1571910978","https://openalex.org/W1575984269","https://openalex.org/W1596454024","https://openalex.org/W1604645679","https://openalex.org/W1606298359","https://openalex.org/W1631395930","https://openalex.org/W1640813462","https://openalex.org/W1724512254","https://openalex.org/W1817337740","https://openalex.org/W1842943643","https://openalex.org/W1852811226","https://openalex.org/W1857766814","https://openalex.org/W1890532746","https://openalex.org/W1921076722","https://openalex.org/W1930773806","https://openalex.org/W1946088674","https://openalex.org/W1954982245","https://openalex.org/W1964658039","https://openalex.org/W1965664876","https://openalex.org/W1966725512","https://openalex.org/W1967266026","https://openalex.org/W1967759078","https://openalex.org/W1969507577","https://openalex.org/W1970291858","https://openalex.org/W1970801772","https://openalex.org/W1971814935","https://openalex.org/W1972036696","https://openalex.org/W1972275692","https://openalex.org/W1973794733","https://openalex.org/W1973869185","https://openalex.org/W1975324295","https://openalex.org/W1976739900","https://openalex.org/W1977210835","https://openalex.org/W1977299280","https://openalex.org/W1977688398","https://openalex.org/W1977995035","https://openalex.org/W1979814807","https://openalex.org/W1980332250","https://openalex.org/W1981262066","https://openalex.org/W1982990560","https://openalex.org/W1983339006","https://openalex.org/W1985364817","https://openalex.org/W1986097125","https://openalex.org/W1987468551","https://openalex.org/W1988666643","https://openalex.org/W1989090634","https://openalex.org/W1989281114","https://openalex.org/W1989374634","https://openalex.org/W1989604593","https://openalex.org/W1989718881","https://openalex.org/W1990768206","https://openalex.org/W1991856499","https://openalex.org/W1992621257","https://openalex.org/W1992768239","https://openalex.org/W1995506998","https://openalex.org/W1995530329","https://openalex.org/W1996513552","https://openalex.org/W1997006958","https://openalex.org/W1997271589","https://openalex.org/W2001026744","https://openalex.org/W2001429538","https://openalex.org/W2001801229","https://openalex.org/W2002035222","https://openalex.org/W2003736664","https://openalex.org/W2005273809","https://openalex.org/W2007702182","https://openalex.org/W2007939817","https://openalex.org/W2009369591","https://openalex.org/W2010293066","https://openalex.org/W2010453211","https://openalex.org/W2010832638","https://openalex.org/W2011202983","https://openalex.org/W2011642803","https://openalex.org/W2011947629","https://openalex.org/W2012750958","https://openalex.org/W2013189759","https://openalex.org/W2015270157","https://openalex.org/W2015519364","https://openalex.org/W2016693266","https://openalex.org/W2017372544","https://openalex.org/W2017528068","https://openalex.org/W2020422405","https://openalex.org/W2022026311","https://openalex.org/W2023380771","https://openalex.org/W2023430120","https://openalex.org/W2027378848","https://openalex.org/W2027699993","https://openalex.org/W2028071765","https://openalex.org/W2029051221","https://openalex.org/W2029675195","https://openalex.org/W2031976497","https://openalex.org/W2035209944","https://openalex.org/W2035369088","https://openalex.org/W2036949285","https://openalex.org/W2037007989","https://openalex.org/W2037061225","https://openalex.org/W2038339415","https://openalex.org/W2038696352","https://openalex.org/W2039093900","https://openalex.org/W2042485805","https://openalex.org/W2042784167","https://openalex.org/W2043310375","https://openalex.org/W2043840480","https://openalex.org/W2043902549","https://openalex.org/W2044607153","https://openalex.org/W2045069202","https://openalex.org/W2045291494","https://openalex.org/W2045936409","https://openalex.org/W2046306641","https://openalex.org/W2047688954","https://openalex.org/W2048882653","https://openalex.org/W2050412379","https://openalex.org/W2050650124","https://openalex.org/W2051813818","https://openalex.org/W2052812059","https://openalex.org/W2053693231","https://openalex.org/W2054151200","https://openalex.org/W2054306003","https://openalex.org/W2055004201","https://openalex.org/W2055824128","https://openalex.org/W2056016311","https://openalex.org/W2056843474","https://openalex.org/W2057514048","https://openalex.org/W2058322041","https://openalex.org/W2059126886","https://openalex.org/W2059158315","https://openalex.org/W2059165573","https://openalex.org/W2059168179","https://openalex.org/W2059311670","https://openalex.org/W2060742288","https://openalex.org/W2061125466","https://openalex.org/W2061468529","https://openalex.org/W2062772596","https://openalex.org/W2063568492","https://openalex.org/W2065783672","https://openalex.org/W2067376187","https://openalex.org/W2069199400","https://openalex.org/W2069467726","https://openalex.org/W2069853753","https://openalex.org/W2072731476","https://openalex.org/W2074790526","https://openalex.org/W2074888570","https://openalex.org/W2076480659","https://openalex.org/W2076956056","https://openalex.org/W2077986050","https://openalex.org/W2079290252","https://openalex.org/W2079386317","https://openalex.org/W2079506023","https://openalex.org/W2079574569","https://openalex.org/W2080360085","https://openalex.org/W2081854672","https://openalex.org/W2082783537","https://openalex.org/W2082912416","https://openalex.org/W2083092470","https://openalex.org/W2083327399","https://openalex.org/W2083347345","https://openalex.org/W2084385289","https://openalex.org/W2084954022","https://openalex.org/W2086744196","https://openalex.org/W2086745302","https://openalex.org/W2087527298","https://openalex.org/W2088823531","https://openalex.org/W2089218510","https://openalex.org/W2089548010","https://openalex.org/W2089631233","https://openalex.org/W2090691848","https://openalex.org/W2090985333","https://openalex.org/W2090985516","https://openalex.org/W2091064919","https://openalex.org/W2092104789","https://openalex.org/W2093329656","https://openalex.org/W2093362260","https://openalex.org/W2094200414","https://openalex.org/W2094337333","https://openalex.org/W2094338165","https://openalex.org/W2095069298","https://openalex.org/W2097711594","https://openalex.org/W2097754683","https://openalex.org/W2099139694","https://openalex.org/W2099310552","https://openalex.org/W2099583536","https://openalex.org/W2100342395","https://openalex.org/W2101159007","https://openalex.org/W2101403111","https://openalex.org/W2103989098","https://openalex.org/W2104058491","https://openalex.org/W2106197320","https://openalex.org/W2106791166","https://openalex.org/W2107106369","https://openalex.org/W2107353510","https://openalex.org/W2107664245","https://openalex.org/W2107726648","https://openalex.org/W2108478501","https://openalex.org/W2108825582","https://openalex.org/W2112350806","https://openalex.org/W2112549882","https://openalex.org/W2116562412","https://openalex.org/W2116608195","https://openalex.org/W2117836408","https://openalex.org/W2119767265","https://openalex.org/W2121619780","https://openalex.org/W2121842388","https://openalex.org/W2121876008","https://openalex.org/W2122069573","https://openalex.org/W2126439369","https://openalex.org/W2127205046","https://openalex.org/W2127938920","https://openalex.org/W2128475635","https://openalex.org/W2129617079","https://openalex.org/W2130520983","https://openalex.org/W2131583554","https://openalex.org/W2131717330","https://openalex.org/W2132650229","https://openalex.org/W2134321528","https://openalex.org/W2135123996","https://openalex.org/W2136223185","https://openalex.org/W2136278733","https://openalex.org/W2137898919","https://openalex.org/W2140297626","https://openalex.org/W2141357485","https://openalex.org/W2141383211","https://openalex.org/W2142808792","https://openalex.org/W2143073532","https://openalex.org/W2146480600","https://openalex.org/W2148611562","https://openalex.org/W2149423925","https://openalex.org/W2151011478","https://openalex.org/W2151396228","https://openalex.org/W2151627258","https://openalex.org/W2152059851","https://openalex.org/W2152329008","https://openalex.org/W2152471910","https://openalex.org/W2152978188","https://openalex.org/W2154482949","https://openalex.org/W2156891963","https://openalex.org/W2161092951","https://openalex.org/W2161229567","https://openalex.org/W2161866900","https://openalex.org/W2162198627","https://openalex.org/W2162538050","https://openalex.org/W2165291913","https://openalex.org/W2166015068","https://openalex.org/W2166874352","https://openalex.org/W2167057061","https://openalex.org/W2167739747","https://openalex.org/W2168211018","https://openalex.org/W2170005346","https://openalex.org/W2170064419","https://openalex.org/W2171997622","https://openalex.org/W2203838975","https://openalex.org/W2205931255","https://openalex.org/W2291630343","https://openalex.org/W2317139512","https://openalex.org/W2410088750","https://openalex.org/W2798475978","https://openalex.org/W2886978647","https://openalex.org/W3129543060","https://openalex.org/W4313331945","https://openalex.org/W7095182316"],"related_works":["https://openalex.org/W4246411804","https://openalex.org/W2056843474","https://openalex.org/W7034072602","https://openalex.org/W1850171316","https://openalex.org/W2116474082","https://openalex.org/W1942516902","https://openalex.org/W2111943427","https://openalex.org/W2141357485","https://openalex.org/W7099130545","https://openalex.org/W7098399012"],"abstract_inverted_index":{"Almost":[0],"all":[1],"cells":[2],"in":[3,45,88],"the":[4,33,48,63,81,107],"living":[5],"organism":[6],"have":[7,32],"identical":[8],"genetic":[9],"information,":[10],"but":[11],"each":[12],"cell":[13,74],"type":[14],"expresses":[15],"a":[16],"limited":[17],"number":[18],"of":[19,65,104],"genes.":[20],"This":[21,76,94],"phenomenon":[22],"is":[23,78,86],"regulated":[24],"by":[25],"specific":[26,41,90],"proteins:":[27],"transcription":[28,66,82],"factors.":[29],"These":[30],"factors":[31,67],"ability":[34],"to":[35,72],"recognize":[36],"target":[37],"sequences":[38],"located":[39,44],"at":[40],"regulatory":[42],"fragments":[43],"or":[46,52,56],"surrounding":[47],"gene":[49,58],"(promoter,":[50],"enhancer":[51],"LCR)":[53],"and":[54,100],"activate":[55],"repress":[57],"transcription.":[59],"Like":[60],"many":[61],"genes,":[62],"expression":[64,105],"can":[68],"also":[69],"be":[70],"restricted":[71],"particular":[73],"types.":[75],"thesis":[77],"focused":[79],"on":[80,110],"factor":[83,99],"GATA3,":[84],"which":[85],"expressed":[87],"tissue":[89],"manner":[91],"during":[92],"development.":[93],"chapter":[95],"will":[96],"introduce":[97],"this":[98],"describes":[101],"its":[102],"sites":[103],"with":[106],"main":[108],"focus":[109],"skin.":[111]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}