{"id":"https://openalex.org/W2154652225","doi":"https://doi.org/10.1016/j.bpj.2015.03.050","title":"Polycystin-2 (TRPP2) Regulation by Ca2+ Is Effected and Diversified by Actin-Binding Proteins","display_name":"Polycystin-2 (TRPP2) Regulation by Ca2+ Is Effected and Diversified by Actin-Binding Proteins","publication_year":2015,"publication_date":"2015-05-01","ids":{"openalex":"https://openalex.org/W2154652225","doi":"https://doi.org/10.1016/j.bpj.2015.03.050","mag":"2154652225","pmid":"https://pubmed.ncbi.nlm.nih.gov/25954877","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4423068"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpj.2015.03.050","doi":"https://doi.org/10.1016/j.bpj.2015.03.050","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2015.03.050","pdf_url":"http://www.cell.com/article/S0006349515003380/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S0006349515003380/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049277864","display_name":"Mar\u00eda del Roc\u00edo Cantero","orcid":"https://orcid.org/0000-0002-9690-8413","observed_orcids":["https://orcid.org/0000-0002-9690-8413"]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Mar\u00eda\u00a0del\u00a0Roc\u00edo Cantero","raw_affiliation_strings":["C\u00e1tedra de Biof\u00edsica, Facultad de Odontolog\u00eda, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"C\u00e1tedra de Biof\u00edsica, Facultad de Odontolog\u00eda, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065381860","display_name":"Horacio F. Cantiello","orcid":"https://orcid.org/0000-0001-7973-0804","observed_orcids":["https://orcid.org/0000-0001-7973-0804"]},"institutions":[{"id":"https://openalex.org/I24354313","display_name":"Universidad de Buenos Aires","ror":"https://ror.org/0081fs513","country_code":"AR","type":"education","lineage":["https://openalex.org/I24354313"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Horacio\u00a0F. Cantiello","raw_affiliation_strings":["C\u00e1tedra de Biof\u00edsica, Facultad de Odontolog\u00eda, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina. Electronic address: hcantiello@yahoo.com.ar","C\u00e1tedra de Biof\u00edsica, Facultad de Odontolog\u00eda, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"C\u00e1tedra de Biof\u00edsica, Facultad de Odontolog\u00eda, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina. Electronic address: hcantiello@yahoo.com.ar","institution_ids":["https://openalex.org/I24354313"]},{"raw_affiliation_string":"C\u00e1tedra de Biof\u00edsica, Facultad de Odontolog\u00eda, Universidad de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina","institution_ids":["https://openalex.org/I24354313"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5065381860"],"corresponding_institution_ids":["https://openalex.org/I24354313"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.8671,"has_fulltext":true,"cited_by_count":10,"citation_normalized_percentile":{"value":0.7025463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"108","issue":"9","first_page":"2191","last_page":"2200"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.8339999914169312,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.8339999914169312,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.11569999903440475,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13415","display_name":"Calcium signaling and nucleotide metabolism","score":0.022199999541044235,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polycystin-2","display_name":"polycystin-2","score":0.9940000176429749},{"id":"https://openalex.org/keywords/trp-p-2","display_name":"Trp-P-2","score":0.9990000128746033},{"id":"https://openalex.org/keywords/actin-binding-proteins","display_name":"actin-binding proteins","score":0.9100000262260437},{"id":"https://openalex.org/keywords/alpha-actinin","display_name":"alpha-actinin","score":0.8199999928474426},{"id":"https://openalex.org/keywords/filamin","display_name":"filamin","score":0.996999979019165},{"id":"https://openalex.org/keywords/gelsolin","display_name":"gelsolin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/profilin","display_name":"profilin","score":1.0},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.8500000238418579},{"id":"https://openalex.org/keywords/transient-receptor-potential-channels","display_name":"TRP channels","score":0.8579999804496765},{"id":"https://openalex.org/keywords/syncytiotrophoblast","display_name":"syncytiotrophoblast","score":0.8149999976158142},{"id":"https://openalex.org/keywords/non-selective-cation-channels","display_name":"non-selective cation channels","score":0.7210000157356262}],"concepts":[{"id":"https://openalex.org/C80722340","wikidata":"https://www.wikidata.org/wiki/Q18297560","display_name":"Gelsolin","level":3,"score":0.7447558641433716},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.5971041917800903},{"id":"https://openalex.org/C130861313","wikidata":"https://www.wikidata.org/wiki/Q3775363","display_name":"Actin-binding protein","level":5,"score":0.5941466093063354},{"id":"https://openalex.org/C20563397","wikidata":"https://www.wikidata.org/wiki/Q410803","display_name":"Filamin","level":4,"score":0.5941038131713867},{"id":"https://openalex.org/C167007842","wikidata":"https://www.wikidata.org/wiki/Q15322678","display_name":"TRPC1","level":4,"score":0.5790798664093018},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5627062320709229},{"id":"https://openalex.org/C2993400109","wikidata":"https://www.wikidata.org/wiki/Q329638","display_name":"Actin cytoskeleton","level":4,"score":0.554712176322937},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5392128229141235},{"id":"https://openalex.org/C155164980","wikidata":"https://www.wikidata.org/wiki/Q304043","display_name":"Transient receptor potential channel","level":3,"score":0.5137666463851929},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4133458137512207},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.39796286821365356},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.3789933919906616},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3131280243396759},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2568296194076538},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.1568945050239563}],"mesh":[{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008051","descriptor_name":"Lipid Bilayers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008840","descriptor_name":"Microfilament Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008841","descriptor_name":"Actin Cytoskeleton","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050396","descriptor_name":"TRPP Cation Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.bpj.2015.03.050","doi":"https://doi.org/10.1016/j.bpj.2015.03.050","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2015.03.050","pdf_url":"http://www.cell.com/article/S0006349515003380/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4423068","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4423068","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophys J","raw_type":"Text"},{"id":"pmid:25954877","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25954877","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical journal","raw_type":"Journal Article"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/38725","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/38725","pdf_url":null,"source":{"id":"https://openalex.org/S4306401400","display_name":"Conicet","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210104196","host_organization_name":"Centro Cient\u00edfico Tecnol\u00f3gico - Nordeste","host_organization_lineage":["https://openalex.org/I4210104196"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.bpj.2015.03.050","doi":"https://doi.org/10.1016/j.bpj.2015.03.050","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpj.2015.03.050","pdf_url":"http://www.cell.com/article/S0006349515003380/pdf","source":{"id":"https://openalex.org/S98085912","display_name":"Biophysical Journal","issn_l":"0006-3495","issn":["0006-3495","1542-0086"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biophysical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2154652225.pdf","grobid_xml":"https://content.openalex.org/works/W2154652225.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1527797749","https://openalex.org/W1563009973","https://openalex.org/W1569504141","https://openalex.org/W1911167061","https://openalex.org/W1965310734","https://openalex.org/W1966021507","https://openalex.org/W1966824637","https://openalex.org/W1970644175","https://openalex.org/W1971530528","https://openalex.org/W1972884505","https://openalex.org/W1990232581","https://openalex.org/W1993228729","https://openalex.org/W1997958675","https://openalex.org/W2001312631","https://openalex.org/W2001536559","https://openalex.org/W2005026678","https://openalex.org/W2014264816","https://openalex.org/W2022209112","https://openalex.org/W2026132650","https://openalex.org/W2028218115","https://openalex.org/W2028229711","https://openalex.org/W2030388894","https://openalex.org/W2038567992","https://openalex.org/W2059403084","https://openalex.org/W2063035654","https://openalex.org/W2065950525","https://openalex.org/W2070323799","https://openalex.org/W2089607905","https://openalex.org/W2111432014","https://openalex.org/W2116269882","https://openalex.org/W2119371526","https://openalex.org/W2128641642","https://openalex.org/W2131427311","https://openalex.org/W2134643287","https://openalex.org/W2136875701","https://openalex.org/W2139555679","https://openalex.org/W2147614625","https://openalex.org/W2154694053","https://openalex.org/W2157522734","https://openalex.org/W2163151375","https://openalex.org/W2164020057","https://openalex.org/W2171774082","https://openalex.org/W2329321343","https://openalex.org/W3127611755","https://openalex.org/W4244843546"],"related_works":["https://openalex.org/W2053223960","https://openalex.org/W1971530528","https://openalex.org/W2024037332","https://openalex.org/W1527797749","https://openalex.org/W2075567213","https://openalex.org/W4214867605","https://openalex.org/W4362585694","https://openalex.org/W4220976469","https://openalex.org/W2054531789","https://openalex.org/W2517199713"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}