{"id":"https://openalex.org/W2154100133","doi":"https://doi.org/10.1371/journal.pgen.1003225","title":"Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers","display_name":"Loci Associated with N-Glycosylation of Human Immunoglobulin G Show Pleiotropy with Autoimmune Diseases and Haematological Cancers","publication_year":2013,"publication_date":"2013-01-31","ids":{"openalex":"https://openalex.org/W2154100133","doi":"https://doi.org/10.1371/journal.pgen.1003225","mag":"2154100133","pmid":"https://pubmed.ncbi.nlm.nih.gov/23382691","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3561084"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pgen.1003225","doi":"https://doi.org/10.1371/journal.pgen.1003225","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1003225","pdf_url":null,"source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Genetics","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1371/journal.pgen.1003225","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030718200","display_name":"Gordan Lauc","orcid":"https://orcid.org/0000-0003-1840-9560","observed_orcids":["https://orcid.org/0000-0003-1840-9560"]},"institutions":[{"id":"https://openalex.org/I181343428","display_name":"University of Zagreb","ror":"https://ror.org/00mv6sv71","country_code":"HR","type":"education","lineage":["https://openalex.org/I181343428"]},{"id":"https://openalex.org/I4210125726","display_name":"Genos (Croatia)","ror":"https://ror.org/03av1g763","country_code":"HR","type":"company","lineage":["https://openalex.org/I4210125726"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Gordan Lauc","raw_affiliation_strings":["Glycobiology Laboratory, Genos, Zagreb, Croatia","Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glycobiology Laboratory, Genos, Zagreb, Croatia","institution_ids":["https://openalex.org/I4210125726"]},{"raw_affiliation_string":"Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia","institution_ids":["https://openalex.org/I181343428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011940218","display_name":"Jennifer E. Huffman","orcid":"https://orcid.org/0000-0002-9672-2491","observed_orcids":["https://orcid.org/0000-0002-9672-2491"]},"institutions":[{"id":"https://openalex.org/I4210158898","display_name":"Institute of Genetics and Cancer","ror":"https://ror.org/05hygey35","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210158898","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jennifer E. Huffman","raw_affiliation_strings":["Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210158898","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090649082","display_name":"Maja Pu\u010di\u0107\u2010Bakovi\u0107","orcid":"https://orcid.org/0000-0003-0866-623X","observed_orcids":["https://orcid.org/0000-0003-0866-623X"]},"institutions":[{"id":"https://openalex.org/I4210125726","display_name":"Genos (Croatia)","ror":"https://ror.org/03av1g763","country_code":"HR","type":"company","lineage":["https://openalex.org/I4210125726"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Maja Pu\u010di\u0107","raw_affiliation_strings":["Glycobiology Laboratory, Genos, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glycobiology Laboratory, Genos, Zagreb, Croatia","institution_ids":["https://openalex.org/I4210125726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062775146","display_name":"Lina Zgaga","orcid":"https://orcid.org/0000-0003-4089-9703","observed_orcids":["https://orcid.org/0000-0003-4089-9703"]},"institutions":[{"id":"https://openalex.org/I181343428","display_name":"University of Zagreb","ror":"https://ror.org/00mv6sv71","country_code":"HR","type":"education","lineage":["https://openalex.org/I181343428"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB","HR"],"is_corresponding":false,"raw_author_name":"Lina Zgaga","raw_affiliation_strings":["Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","Faculty of Medicine, University of Zagreb, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Faculty of Medicine, University of Zagreb, Zagreb, Croatia","institution_ids":["https://openalex.org/I181343428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033836686","display_name":"B Adamczyk","orcid":"https://orcid.org/0000-0001-9111-1301","observed_orcids":["https://orcid.org/0000-0001-9111-1301"]},"institutions":[{"id":"https://openalex.org/I4210153114","display_name":"National Institute for Bioprocessing Research and Training","ror":"https://ror.org/04s8gft68","country_code":"IE","type":"facility","lineage":["https://openalex.org/I4210153114"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Barbara Adamczyk","raw_affiliation_strings":["National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Laboratory, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Laboratory, Dublin, Ireland","institution_ids":["https://openalex.org/I4210153114"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049305039","display_name":"Ana Mu\u017eini\u0107","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125726","display_name":"Genos (Croatia)","ror":"https://ror.org/03av1g763","country_code":"HR","type":"company","lineage":["https://openalex.org/I4210125726"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Ana Mu\u017eini\u0107","raw_affiliation_strings":["Glycobiology Laboratory, Genos, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glycobiology Laboratory, Genos, Zagreb, Croatia","institution_ids":["https://openalex.org/I4210125726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003222189","display_name":"Mislav Novokmet","orcid":"https://orcid.org/0000-0002-7338-2017","observed_orcids":["https://orcid.org/0000-0002-7338-2017"]},"institutions":[{"id":"https://openalex.org/I4210125726","display_name":"Genos (Croatia)","ror":"https://ror.org/03av1g763","country_code":"HR","type":"company","lineage":["https://openalex.org/I4210125726"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Mislav Novokmet","raw_affiliation_strings":["Glycobiology Laboratory, Genos, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glycobiology Laboratory, Genos, Zagreb, Croatia","institution_ids":["https://openalex.org/I4210125726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052415661","display_name":"Ozren Pola\u0161ek","orcid":"https://orcid.org/0000-0002-5765-1862","observed_orcids":["https://orcid.org/0000-0002-5765-1862"]},"institutions":[{"id":"https://openalex.org/I92251255","display_name":"University of Split","ror":"https://ror.org/00m31ft63","country_code":"HR","type":"education","lineage":["https://openalex.org/I92251255"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Ozren Pola\u0161ek","raw_affiliation_strings":["Faculty of Medicine, University of Split, Split, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, University of Split, Split, Croatia","institution_ids":["https://openalex.org/I92251255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064938738","display_name":"Olga Gornik","orcid":"https://orcid.org/0000-0002-6157-6252","observed_orcids":["https://orcid.org/0000-0002-6157-6252"]},"institutions":[{"id":"https://openalex.org/I181343428","display_name":"University of Zagreb","ror":"https://ror.org/00mv6sv71","country_code":"HR","type":"education","lineage":["https://openalex.org/I181343428"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Olga Gornik","raw_affiliation_strings":["Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia","institution_ids":["https://openalex.org/I181343428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059813799","display_name":"Jasminka Kri\u0161ti\u0107","orcid":"https://orcid.org/0000-0001-8463-3814","observed_orcids":["https://orcid.org/0000-0001-8463-3814"]},"institutions":[{"id":"https://openalex.org/I4210125726","display_name":"Genos (Croatia)","ror":"https://ror.org/03av1g763","country_code":"HR","type":"company","lineage":["https://openalex.org/I4210125726"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Jasminka Kri\u0161ti\u0107","raw_affiliation_strings":["Glycobiology Laboratory, Genos, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glycobiology Laboratory, Genos, Zagreb, Croatia","institution_ids":["https://openalex.org/I4210125726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051077634","display_name":"Toma Keser","orcid":"https://orcid.org/0000-0003-2759-3742","observed_orcids":["https://orcid.org/0000-0003-2759-3742"]},"institutions":[{"id":"https://openalex.org/I181343428","display_name":"University of Zagreb","ror":"https://ror.org/00mv6sv71","country_code":"HR","type":"education","lineage":["https://openalex.org/I181343428"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Toma Keser","raw_affiliation_strings":["Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia","institution_ids":["https://openalex.org/I181343428"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071827492","display_name":"V\u00e9ronique Vitart","orcid":"https://orcid.org/0000-0002-4991-3797","observed_orcids":["https://orcid.org/0000-0002-4991-3797"]},"institutions":[{"id":"https://openalex.org/I4210158898","display_name":"Institute of Genetics and Cancer","ror":"https://ror.org/05hygey35","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210158898","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Veronique Vitart","raw_affiliation_strings":["Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210158898","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020171094","display_name":"Blanca Scheijen","orcid":"https://orcid.org/0000-0001-8029-9230","observed_orcids":["https://orcid.org/0000-0001-8029-9230"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Blanca Scheijen","raw_affiliation_strings":["Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084921557","display_name":"Hae\u2010Won Uh","orcid":"https://orcid.org/0000-0003-4195-7872","observed_orcids":["https://orcid.org/0000-0003-4195-7872"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]},{"id":"https://openalex.org/I4210131551","display_name":"Netherlands Consortium for Healthy Ageing","ror":"https://ror.org/03wnqyy64","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210131551"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hae-Won Uh","raw_affiliation_strings":["Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands","Netherlands Consortium for Healthy Aging, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]},{"raw_affiliation_string":"Netherlands Consortium for Healthy Aging, Leiden, The Netherlands","institution_ids":["https://openalex.org/I4210131551"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108703277","display_name":"Mariam Molokhia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mariam Molokhia","raw_affiliation_strings":["Department of Primary Care and Public Health Sciences, Kings College London, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Primary Care and Public Health Sciences, Kings College London, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046753912","display_name":"Alan Leslie Patrick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802945493","display_name":"Port of Spain General Hospital","ror":"https://ror.org/03cjy1t09","country_code":"TT","type":"healthcare","lineage":["https://openalex.org/I2802945493"]}],"countries":["TT"],"is_corresponding":false,"raw_author_name":"Alan Leslie Patrick","raw_affiliation_strings":["Kavanagh St. Medical Centre, Port of Spain, Trinidad and Tobago"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kavanagh St. Medical Centre, Port of Spain, Trinidad and Tobago","institution_ids":["https://openalex.org/I2802945493"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039750697","display_name":"Paul McKeigue","orcid":"https://orcid.org/0000-0002-5217-1034","observed_orcids":["https://orcid.org/0000-0002-5217-1034"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Paul McKeigue","raw_affiliation_strings":["Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019362259","display_name":"Ivana Kol\u010di\u0107","orcid":"https://orcid.org/0000-0001-7918-6052","observed_orcids":["https://orcid.org/0000-0001-7918-6052"]},"institutions":[{"id":"https://openalex.org/I92251255","display_name":"University of Split","ror":"https://ror.org/00m31ft63","country_code":"HR","type":"education","lineage":["https://openalex.org/I92251255"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Ivana Kol\u010di\u0107","raw_affiliation_strings":["Faculty of Medicine, University of Split, Split, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, University of Split, Split, Croatia","institution_ids":["https://openalex.org/I92251255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009128656","display_name":"Ivan Kre\u0161imir Luki\u0107","orcid":"https://orcid.org/0000-0002-3530-5184","observed_orcids":["https://orcid.org/0000-0002-3530-5184"]},"institutions":[{"id":"https://openalex.org/I92251255","display_name":"University of Split","ror":"https://ror.org/00m31ft63","country_code":"HR","type":"education","lineage":["https://openalex.org/I92251255"]}],"countries":["HR"],"is_corresponding":false,"raw_author_name":"Ivan Kre\u0161imir Luki\u0107","raw_affiliation_strings":["Faculty of Medicine, University of Split, Split, Croatia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medicine, University of Split, Split, Croatia","institution_ids":["https://openalex.org/I92251255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027762731","display_name":"Olivia V. Swann","orcid":"https://orcid.org/0000-0001-7386-2849","observed_orcids":["https://orcid.org/0000-0001-7386-2849"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Olivia Swann","raw_affiliation_strings":["Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038325579","display_name":"Frank N. van Leeuwen","orcid":"https://orcid.org/0000-0003-1107-6513","observed_orcids":["https://orcid.org/0000-0003-1107-6513","https://orcid.org/0000-0002-5468-7042"]},"institutions":[{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Frank N. van Leeuwen","raw_affiliation_strings":["Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I2802934949"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080379557","display_name":"L. Renee Ruhaak","orcid":"https://orcid.org/0000-0003-3737-3807","observed_orcids":["https://orcid.org/0000-0003-3737-3807"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Renee Ruhaak","raw_affiliation_strings":["Department of Chemistry, University of California Davis, Davis, California, United States of America"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of California Davis, Davis, California, United States of America","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074193742","display_name":"Jeanine J. Houwing\u2010Duistermaat","orcid":"https://orcid.org/0000-0002-4505-7137","observed_orcids":["https://orcid.org/0000-0002-4505-7137"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jeanine J. Houwing-Duistermaat","raw_affiliation_strings":["Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071478025","display_name":"P. Eline Slagboom","orcid":"https://orcid.org/0000-0002-2875-4723","observed_orcids":["https://orcid.org/0000-0002-2875-4723"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]},{"id":"https://openalex.org/I4210131551","display_name":"Netherlands Consortium for Healthy Ageing","ror":"https://ror.org/03wnqyy64","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210131551"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"P. Eline Slagboom","raw_affiliation_strings":["Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands","Netherlands Consortium for Healthy Aging, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]},{"raw_affiliation_string":"Netherlands Consortium for Healthy Aging, Leiden, The Netherlands","institution_ids":["https://openalex.org/I4210131551"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064751516","display_name":"Marian Beekman","orcid":"https://orcid.org/0000-0003-0585-6206","observed_orcids":["https://orcid.org/0000-0003-0585-6206"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]},{"id":"https://openalex.org/I4210131551","display_name":"Netherlands Consortium for Healthy Ageing","ror":"https://ror.org/03wnqyy64","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210131551"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marian Beekman","raw_affiliation_strings":["Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands","Netherlands Consortium for Healthy Aging, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]},{"raw_affiliation_string":"Netherlands Consortium for Healthy Aging, Leiden, The Netherlands","institution_ids":["https://openalex.org/I4210131551"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111897494","display_name":"Anton J.M. de Craen","orcid":"https://orcid.org/0000-0001-9314-123X","observed_orcids":["https://orcid.org/0000-0001-9314-123X"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Anton J. M. de Craen","raw_affiliation_strings":["Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108073298","display_name":"Andr\u00e9 M. Deelder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 M. Deelder","raw_affiliation_strings":["Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085694854","display_name":"Qiang Zeng","orcid":"https://orcid.org/0000-0002-4961-0171","observed_orcids":["https://orcid.org/0000-0002-4961-0171"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiang Zeng","raw_affiliation_strings":["Chinese PLA General Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100391883","display_name":"Wei Wang","orcid":"https://orcid.org/0000-0002-1430-1360","observed_orcids":["https://orcid.org/0000-0002-1430-1360"]},"institutions":[{"id":"https://openalex.org/I12079687","display_name":"Edith Cowan University","ror":"https://ror.org/05jhnwe22","country_code":"AU","type":"education","lineage":["https://openalex.org/I12079687"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["AU","CN"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Graduate University, Chinese Academy of Sciences, Beijing, China","School of Medical Sciences, Edith Cowan University, Perth, Australia","School of Public Health, Capital Medical University, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate University, Chinese Academy of Sciences, Beijing, China","institution_ids":["https://openalex.org/I19820366"]},{"raw_affiliation_string":"School of Medical Sciences, Edith Cowan University, Perth, Australia","institution_ids":["https://openalex.org/I12079687"]},{"raw_affiliation_string":"School of Public Health, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050574230","display_name":"Nicholas Dixon Hastie","orcid":"https://orcid.org/0000-0002-0515-168X","observed_orcids":["https://orcid.org/0000-0002-0515-168X"]},"institutions":[{"id":"https://openalex.org/I4210158898","display_name":"Institute of Genetics and Cancer","ror":"https://ror.org/05hygey35","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210158898","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicholas D. Hastie","raw_affiliation_strings":["Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210158898","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025350717","display_name":"Ulf B Gyllensten","orcid":"https://orcid.org/0000-0002-6316-3355","observed_orcids":["https://orcid.org/0000-0002-6316-3355"]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]},{"id":"https://openalex.org/I2800139495","display_name":"Science for Life Laboratory","ror":"https://ror.org/04ev03g22","country_code":"SE","type":"facility","lineage":["https://openalex.org/I2800139495"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Ulf Gyllensten","raw_affiliation_strings":["Department of Immunology, Genetics, and Pathology, SciLifeLab Uppsala, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Genetics, and Pathology, SciLifeLab Uppsala, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679","https://openalex.org/I2800139495"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057866160","display_name":"James F. Wilson","orcid":"https://orcid.org/0000-0001-5751-9178","observed_orcids":["https://orcid.org/0000-0001-5751-9178","https://orcid.org/0000-0003-0548-2486"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"James F. Wilson","raw_affiliation_strings":["Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065397150","display_name":"Manfred Wuhrer","orcid":"https://orcid.org/0000-0002-0814-4995","observed_orcids":["https://orcid.org/0000-0002-0814-4995"]},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Manfred Wuhrer","raw_affiliation_strings":["Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Mass Spectrometry Unit, Department of Parasitology, Leiden University Medical Center, Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109181222","display_name":"Alan F. Wright","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210158898","display_name":"Institute of Genetics and Cancer","ror":"https://ror.org/05hygey35","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210158898","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alan F. Wright","raw_affiliation_strings":["Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210158898","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082473050","display_name":"Pauline Mary Rudd","orcid":"https://orcid.org/0000-0003-3880-0532","observed_orcids":["https://orcid.org/0000-0003-3880-0532"]},"institutions":[{"id":"https://openalex.org/I4210153114","display_name":"National Institute for Bioprocessing Research and Training","ror":"https://ror.org/04s8gft68","country_code":"IE","type":"facility","lineage":["https://openalex.org/I4210153114"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Pauline M. Rudd","raw_affiliation_strings":["National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Laboratory, Dublin, Ireland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute for Bioprocessing Research and Training, Dublin-Oxford Glycobiology Laboratory, Dublin, Ireland","institution_ids":["https://openalex.org/I4210153114"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045835301","display_name":"Caroline Hayward","orcid":"https://orcid.org/0000-0002-9405-9550","observed_orcids":["https://orcid.org/0000-0002-9405-9550"]},"institutions":[{"id":"https://openalex.org/I4210158898","display_name":"Institute of Genetics and Cancer","ror":"https://ror.org/05hygey35","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210158898","https://openalex.org/I90344618","https://openalex.org/I98677209"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Caroline Hayward","raw_affiliation_strings":["Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I4210158898","https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003919256","display_name":"Yurii S. Aulchenko","orcid":"https://orcid.org/0000-0002-7899-1575","observed_orcids":["https://orcid.org/0000-0002-7899-1575"]},"institutions":[{"id":"https://openalex.org/I4210116466","display_name":"Institute of Cytology and Genetics","ror":"https://ror.org/0277xgb12","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I188973947","https://openalex.org/I4210116466","https://openalex.org/I4210127387","https://openalex.org/I4210129690"]},{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB","RU"],"is_corresponding":false,"raw_author_name":"Yurii Aulchenko","raw_affiliation_strings":["Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]},{"raw_affiliation_string":"Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia","institution_ids":["https://openalex.org/I4210116466"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111959479","display_name":"Harry Campbell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Harry Campbell","raw_affiliation_strings":["Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038431304","display_name":"Igor Rudan","orcid":"https://orcid.org/0000-0001-6993-6884","observed_orcids":["https://orcid.org/0000-0001-6993-6884"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Igor Rudan","raw_affiliation_strings":["Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]}],"institutions":[],"countries_distinct_count":10,"institutions_distinct_count":19,"corresponding_author_ids":["https://openalex.org/A5038431304"],"corresponding_institution_ids":["https://openalex.org/I98677209"],"apc_list":{"value":3043,"currency":"USD","value_usd":3043},"apc_paid":{"value":3043,"currency":"USD","value_usd":3043},"fwci":2.8232,"has_fulltext":true,"cited_by_count":360,"citation_normalized_percentile":{"value":0.93972135,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"9","issue":"1","first_page":"e1003225","last_page":"e1003225"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.013100000098347664,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/igg-n-glycosylation","display_name":"IgG N-glycosylation","score":0.9789999723434448},{"id":"https://openalex.org/keywords/pleiotropy","display_name":"pleiotropy","score":0.871999979019165},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.9700000286102295},{"id":"https://openalex.org/keywords/hematological-cancer","display_name":"hematologic cancer","score":0.9739999771118164},{"id":"https://openalex.org/keywords/b4galt1","display_name":"B4GALT1","score":0.8019999861717224},{"id":"https://openalex.org/keywords/mgat3","display_name":"MGAT3","score":0.9909999966621399},{"id":"https://openalex.org/keywords/st6gal1","display_name":"ST6GAL1","score":0.8730000257492065},{"id":"https://openalex.org/keywords/fucosyltransferase-8","display_name":"FUT8","score":0.9760000109672546},{"id":"https://openalex.org/keywords/glycosyltransferases","display_name":"glycosyltransferases","score":0.8709999918937683},{"id":"https://openalex.org/keywords/ikzf1","display_name":"IKZF1","score":0.9309999942779541},{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":0.9559999704360962},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.8880000114440918},{"id":"https://openalex.org/keywords/fc-receptor-binding","display_name":"Fc receptor binding","score":0.6449999809265137}],"concepts":[{"id":"https://openalex.org/C158650290","wikidata":"https://www.wikidata.org/wiki/Q3063952","display_name":"Glycome","level":4,"score":0.7415120601654053},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7025826573371887},{"id":"https://openalex.org/C2777313579","wikidata":"https://www.wikidata.org/wiki/Q898365","display_name":"Glycosylation","level":2,"score":0.6070809364318848},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5963041186332703},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.563237190246582},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.45403099060058594},{"id":"https://openalex.org/C2779212266","wikidata":"https://www.wikidata.org/wiki/Q17053974","display_name":"Fucosylation","level":4,"score":0.45147672295570374},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.4305403530597687},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.41258931159973145},{"id":"https://openalex.org/C206212055","wikidata":"https://www.wikidata.org/wiki/Q2553138","display_name":"Glycan","level":3,"score":0.40059685707092285},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.39234229922294617},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3582853078842163},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.34899282455444336},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3281487822532654},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.2637999653816223},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.23522809147834778},{"id":"https://openalex.org/C108625454","wikidata":"https://www.wikidata.org/wiki/Q187126","display_name":"Glycoprotein","level":2,"score":0.1873764991760254},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1483592391014099},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10787686705589294}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009103","descriptor_name":"Multiple Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016695","descriptor_name":"Glycosyltransferases","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016695","descriptor_name":"Glycosyltransferases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019337","descriptor_name":"Hematologic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058685","descriptor_name":"Genetic Pleiotropy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":19,"locations":[{"id":"doi:10.1371/journal.pgen.1003225","doi":"https://doi.org/10.1371/journal.pgen.1003225","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1003225","pdf_url":null,"source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Genetics","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2564879","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/articles/PMC3561084","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3561084","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3561084","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Genet","raw_type":"Text"},{"id":"pmid:23382691","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23382691","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS genetics","raw_type":"Journal Article"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/f155139f-279d-47b8-9402-115e42c8e793","doi":null,"is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/f155139f-279d-47b8-9402-115e42c8e793","pdf_url":"https://www.research.ed.ac.uk/files/8350584/Loci_associated_with_N_glycosylation_of_human_immunoglobulin_g_show_pleiotropy_with_autoimmune_diseases_and_haematological_cancers.pdf","source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:ru:oai:repository.ubn.ru.nl:2066/118733","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2066/118733","pdf_url":"http://hdl.handle.net/2066/118733","source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plos Genetics, 9, e1003225","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.874.3703","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.874.3703","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://ro.ecu.edu.au/cgi/viewcontent.cgi?article%3D1005%26context%3Decuworks2013","raw_type":"text"},{"id":"pmh:oai:ro.ecu.edu.au:ecuworks2013-1005","doi":null,"is_oa":true,"landing_page_url":"https://ro.ecu.edu.au/ecuworks2013/6","pdf_url":null,"source":{"id":"https://openalex.org/S2765015692","display_name":"Australasian Journal of Paramedicine","issn_l":"2202-7270","issn":["2202-7270"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20"],"host_organization":"https://openalex.org/I4405272673","host_organization_name":"Australasian College of Paramedicine","host_organization_lineage":["https://openalex.org/I4405272673"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Research outputs 2013","raw_type":"text"},{"id":"pmh:lumc:oai:scholarlypublications.universiteitleiden.nl:item_2988333","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1887/96986","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics, 9(1), -","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:DiVA.org:uu-196758","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-196758","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:RePEc:plo:pgen00:1003225","doi":null,"is_oa":false,"landing_page_url":"https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1003225","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:alma.31UKB_LEU:9940752918902711","doi":null,"is_oa":false,"landing_page_url":"https://scholarlypublications.universiteitleiden.nl/handle/1887/96986","pdf_url":null,"source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics, Vol. 9, no. 1, p. -","raw_type":"http://purl.org/coar/resource_type/c_6501"},{"id":"pmh:oai:doaj.org/article:b199e4ae942e4dc2a7fbc3d1609faf09","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b199e4ae942e4dc2a7fbc3d1609faf09","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics, Vol 9, Iss 1, p e1003225 (2013)","raw_type":"article"},{"id":"pmh:oai:figshare.com:article/155156","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Loci_Associated_with_N_Glycosylation_of_Human_Immunoglobulin_G_Show_Pleiotropy_with_Autoimmune_Diseases_and_Haematological_Cancers__/155156","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dataset"},{"id":"pmh:oai:kclpure.kcl.ac.uk:publications/7978e035-d009-4efa-b820-aa44b524153c","doi":null,"is_oa":false,"landing_page_url":"https://kclpure.kcl.ac.uk/portal/en/publications/7978e035-d009-4efa-b820-aa44b524153c","pdf_url":null,"source":{"id":"https://openalex.org/S4306400216","display_name":"Research Portal (King's College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I183935753","host_organization_name":"King's College London","host_organization_lineage":["https://openalex.org/I183935753"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:openaccess.leidenuniv.nl:1887/96986","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1887/96986","pdf_url":null,"source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"9","raw_type":"Article / Letter to editor"},{"id":"pmh:oai:repository.ubn.ru.nl:2066/118733","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2066/118733","pdf_url":null,"source":{"id":"https://openalex.org/S4306401067","display_name":"Radboud Repository (Radboud University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I145872427","host_organization_name":"Radboud University Nijmegen","host_organization_lineage":["https://openalex.org/I145872427"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Plos Genetics, 9, 1, pp. e1003225","raw_type":"Article / Letter to editor"},{"id":"pmh:oai:scholarlypublications.universiteitleiden.nl:item_2988333","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/1887/96986","pdf_url":null,"source":{"id":"https://openalex.org/S4306400850","display_name":"Leiden Repository (Leiden University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I121797337","host_organization_name":"Leiden University","host_organization_lineage":["https://openalex.org/I121797337"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Genetics","raw_type":"Article / Letter to editor"},{"id":"mag:2752685964","doi":null,"is_oa":false,"landing_page_url":"https://bib.irb.hr/prikazi-rad?&rad=746340","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1371/journal.pgen.1003225","doi":"https://doi.org/10.1371/journal.pgen.1003225","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pgen.1003225","pdf_url":null,"source":{"id":"https://openalex.org/S103870658","display_name":"PLoS Genetics","issn_l":"1553-7390","issn":["1553-7390","1553-7404"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Genetics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G1495020029","display_name":null,"funder_award_id":"050.060.810","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G1689944598","display_name":null,"funder_award_id":"018947","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G2476663878","display_name":null,"funder_award_id":"FP7/2007-2011","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G3001543491","display_name":null,"funder_award_id":"LSHG-CT-2006-018947","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G3828971597","display_name":"Tools for the Detection of  Novel Glyco-biomarkers","funder_award_id":"259869","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G4486034022","display_name":null,"funder_award_id":"SenterNovem IGE05007","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"},{"id":"https://openalex.org/G4571683210","display_name":null,"funder_award_id":"216-1080315-0302","funder_id":"https://openalex.org/F4320322674","funder_display_name":"Hrvatska Zaklada za Znanost"},{"id":"https://openalex.org/G4786922132","display_name":null,"funder_award_id":"04-47","funder_id":"https://openalex.org/F4320322674","funder_display_name":"Hrvatska Zaklada za Znanost"},{"id":"https://openalex.org/G5649515030","display_name":null,"funder_award_id":"LSHG-CT-2006018947","funder_id":"https://openalex.org/F4320322674","funder_display_name":"Hrvatska Zaklada za Znanost"},{"id":"https://openalex.org/G5702163051","display_name":null,"funder_award_id":"FP7/2007","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G5984585972","display_name":"Integrated research on DEvelopmental determinants of Aging and Longevity","funder_award_id":"259679","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G6887627516","display_name":"Centre for Immunity, Infection and Evolution.","funder_award_id":"095831","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"},{"id":"https://openalex.org/G7003971911","display_name":null,"funder_award_id":"FP7/2007","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G73070002","display_name":"Development of carbohydrate array technology to systematically explore the functional role of glycans in healthy and diseased states","funder_award_id":"215536","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7554926542","display_name":"Methods for high-throughput (HTP) analysis of protein glycosylation","funder_award_id":"278535","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G8897002470","display_name":null,"funder_award_id":"2012BAI37B03","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G970400076","display_name":null,"funder_award_id":"LSHG-CT-2006-018947","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320313269","display_name":"Scottish Government","ror":"https://ror.org/04v2xmd71"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320320006","display_name":"Royal Society","ror":"https://ror.org/03wnrjx87"},{"id":"https://openalex.org/F4320320285","display_name":"King's College London","ror":"https://ror.org/0220mzb33"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321079","display_name":"Russian Foundation for Basic Research","ror":"https://ror.org/02mh1ke95"},{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"},{"id":"https://openalex.org/F4320322674","display_name":"Hrvatska Zaklada za Znanost","ror":"https://ror.org/03n51vw80"},{"id":"https://openalex.org/F4320323705","display_name":"Stichting Kinderen Kankervrij","ror":"https://ror.org/05gxzef39"},{"id":"https://openalex.org/F4320328608","display_name":"Centre for Medical Systems Biology","ror":"https://ror.org/00e7dfm13"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2154100133.pdf","grobid_xml":"https://content.openalex.org/works/W2154100133.grobid-xml"},"referenced_works_count":93,"referenced_works":["https://openalex.org/W1691111249","https://openalex.org/W1771609665","https://openalex.org/W1831036856","https://openalex.org/W1965291328","https://openalex.org/W1965399166","https://openalex.org/W1965928933","https://openalex.org/W1971476169","https://openalex.org/W1971490071","https://openalex.org/W1977846646","https://openalex.org/W1979290553","https://openalex.org/W1980725116","https://openalex.org/W1982197692","https://openalex.org/W1984960406","https://openalex.org/W1986262138","https://openalex.org/W1986500198","https://openalex.org/W1989970381","https://openalex.org/W1995118292","https://openalex.org/W1998823290","https://openalex.org/W2005980940","https://openalex.org/W2005998452","https://openalex.org/W2010203932","https://openalex.org/W2016455091","https://openalex.org/W2018338402","https://openalex.org/W2020647630","https://openalex.org/W2021740276","https://openalex.org/W2024108088","https://openalex.org/W2024670158","https://openalex.org/W2026014108","https://openalex.org/W2030932286","https://openalex.org/W2031580483","https://openalex.org/W2032420547","https://openalex.org/W2033783367","https://openalex.org/W2035433348","https://openalex.org/W2040547343","https://openalex.org/W2040891039","https://openalex.org/W2042729575","https://openalex.org/W2043209609","https://openalex.org/W2045605305","https://openalex.org/W2051118090","https://openalex.org/W2053354820","https://openalex.org/W2055973314","https://openalex.org/W2056176185","https://openalex.org/W2060248602","https://openalex.org/W2060364735","https://openalex.org/W2065119658","https://openalex.org/W2071901422","https://openalex.org/W2075620734","https://openalex.org/W2075901113","https://openalex.org/W2079579628","https://openalex.org/W2084136419","https://openalex.org/W2095967880","https://openalex.org/W2099724648","https://openalex.org/W2104785679","https://openalex.org/W2106779017","https://openalex.org/W2108210377","https://openalex.org/W2108963851","https://openalex.org/W2109899118","https://openalex.org/W2112409097","https://openalex.org/W2112916314","https://openalex.org/W2115783720","https://openalex.org/W2116195449","https://openalex.org/W2118448966","https://openalex.org/W2118705425","https://openalex.org/W2119566098","https://openalex.org/W2121576917","https://openalex.org/W2122035554","https://openalex.org/W2127858258","https://openalex.org/W2128316367","https://openalex.org/W2129001769","https://openalex.org/W2137116169","https://openalex.org/W2137354517","https://openalex.org/W2139011450","https://openalex.org/W2140247198","https://openalex.org/W2140723605","https://openalex.org/W2143191132","https://openalex.org/W2143286837","https://openalex.org/W2146203649","https://openalex.org/W2147086116","https://openalex.org/W2148432790","https://openalex.org/W2153622268","https://openalex.org/W2156750419","https://openalex.org/W2161245845","https://openalex.org/W2161605585","https://openalex.org/W2163013660","https://openalex.org/W2163184920","https://openalex.org/W2165872127","https://openalex.org/W2168458391","https://openalex.org/W2169812606","https://openalex.org/W2169923455","https://openalex.org/W2955331105","https://openalex.org/W2963344102","https://openalex.org/W4242768823","https://openalex.org/W4300063384"],"related_works":["https://openalex.org/W2752685964","https://openalex.org/W3134193500","https://openalex.org/W2805874710","https://openalex.org/W2178016194","https://openalex.org/W7100122216","https://openalex.org/W2952580906","https://openalex.org/W3209055786","https://openalex.org/W3213450008","https://openalex.org/W3206624490","https://openalex.org/W2750945087"],"abstract_inverted_index":{"Glycosylation":[0],"of":[1,42,72,76,96,141,197,220,261,282],"immunoglobulin":[2],"G":[3],"(IgG)":[4],"influences":[5],"IgG":[6,21,26,33,61,200,213],"effector":[7],"function":[8],"by":[9],"modulating":[10],"binding":[11],"to":[12,254],"Fc":[13],"receptors.":[14],"To":[15],"identify":[16,255],"genetic":[17],"loci":[18,86,99,108,257,283],"associated":[19,146,210],"with":[20,147,211,226],"glycosylation,":[22],"we":[23,37,59,216],"quantitated":[24],"N-linked":[25],"glycans":[27],"using":[28,44,63,266],"two":[29,95],"approaches.":[30],"After":[31],"isolating":[32],"from":[34,52],"human":[35],"plasma,":[36],"performed":[38],"77":[39],"quantitative":[40],"measurements":[41],"N-glycosylation":[43],"ultra-performance":[45],"liquid":[46],"chromatography":[47],"(UPLC)":[48],"in":[49,68,90,103,130,187,199,204,223,237,285],"2,247":[50],"individuals":[51],"four":[53],"European":[54],"discovery":[55,92],"populations.":[56],"In":[57],"parallel,":[58],"measured":[60],"N-glycans":[62,222],"MALDI-TOF":[64],"mass":[65],"spectrometry":[66],"(MS)":[67],"a":[69,238,262],"replication":[70,105],"cohort":[71],"1,848":[73],"Europeans.":[74],"Meta-analysis":[75],"genome-wide":[77,84],"association":[78],"study":[79,248],"(GWAS)":[80],"results":[81,269],"identified":[82,203],"9":[83],"significant":[85],"(P<2.27":[87],"\u00d7":[88],"10(-9))":[89],"the":[91,97,104,119,193,205,243,276],"analysis":[93,240],"and":[94,101,116,137,149,181,228,232,279,288],"same":[98,194],"(B4GALT1":[100],"MGAT3)":[102],"cohort.":[106],"Four":[107],"contained":[109,122],"genes":[110,123],"encoding":[111],"glycosyltransferases":[112],"(ST6GAL1,":[113],"B4GALT1,":[114],"FUT8,":[115],"MGAT3),":[117],"while":[118],"remaining":[120],"5":[121],"that":[124,250,258],"have":[125,143],"not":[126],"been":[127,144],"previously":[128],"implicated":[129],"protein":[131,265],"glycosylation":[132,201,260],"(IKZF1,":[133],"IL6ST-ANKRD55,":[134],"ABCF2-SMARCD3,":[135],"SUV420H1,":[136],"SMARCB1-DERL3).":[138],"However,":[139],"most":[140],"them":[142],"strongly":[145],"autoimmune":[148,286],"inflammatory":[150],"conditions":[151],"(e.g.,":[152],"systemic":[153],"lupus":[154],"erythematosus,":[155],"rheumatoid":[156],"arthritis,":[157],"ulcerative":[158],"colitis,":[159],"Crohn's":[160],"disease,":[161,168,170],"diabetes":[162],"type":[163],"1,":[164],"multiple":[165,182,212],"sclerosis,":[166],"Graves'":[167],"celiac":[169],"nodular":[171],"sclerosis)":[172],"and/or":[173],"haematological":[174,289],"cancers":[175],"(acute":[176],"lymphoblastic":[177],"leukaemia,":[178],"Hodgkin":[179],"lymphoma,":[180],"myeloma).":[183],"Follow-up":[184],"functional":[185],"experiments":[186],"haplodeficient":[188],"Ikzf1":[189],"knock-out":[190],"mice":[191],"showed":[192],"general":[195],"pattern":[196],"changes":[198],"as":[202],"meta-analysis.":[206],"As":[207],"IKZF1":[208],"was":[209],"N-glycan":[214],"traits,":[215],"explored":[217],"biomarker":[218],"potential":[219],"affected":[221],"101":[224],"cases":[225],"SLE":[227],"183":[229],"matched":[230],"controls":[231],"demonstrated":[233],"substantial":[234],"discriminative":[235],"power":[236],"ROC-curve":[239],"(area":[241],"under":[242],"curve":[244],"=":[245],"0.842).":[246],"Our":[247],"shows":[249],"it":[251],"is":[252],"possible":[253],"new":[256],"control":[259],"single":[263],"plasma":[264],"GWAS.":[267],"The":[268],"may":[270],"also":[271],"provide":[272],"an":[273],"explanation":[274],"for":[275],"reported":[277],"pleiotropy":[278],"antagonistic":[280],"effects":[281],"involved":[284],"diseases":[287],"cancer.":[290]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":17},{"year":2024,"cited_by_count":17},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":29},{"year":2021,"cited_by_count":42},{"year":2020,"cited_by_count":30},{"year":2019,"cited_by_count":29},{"year":2018,"cited_by_count":29},{"year":2017,"cited_by_count":30},{"year":2016,"cited_by_count":38},{"year":2015,"cited_by_count":18},{"year":2014,"cited_by_count":25},{"year":2013,"cited_by_count":11}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}