{"id":"https://openalex.org/W2154032335","doi":"https://doi.org/10.1084/jem.175.5.1213","title":"Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells.","display_name":"Continuous anti-interleukin 10 antibody administration depletes mice of Ly-1 B cells but not conventional B cells.","publication_year":1992,"publication_date":"1992-05-01","ids":{"openalex":"https://openalex.org/W2154032335","doi":"https://doi.org/10.1084/jem.175.5.1213","mag":"2154032335","pmid":"https://pubmed.ncbi.nlm.nih.gov/1533240","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2119200"},"language":"en","primary_location":{"id":"doi:10.1084/jem.175.5.1213","doi":"https://doi.org/10.1084/jem.175.5.1213","is_oa":false,"landing_page_url":"https://doi.org/10.1084/jem.175.5.1213","pdf_url":null,"source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2119200","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"H Ishida","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H Ishida","raw_affiliation_strings":["DNAX Research Institute, Palo Alto, California 94304"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DNAX Research Institute, Palo Alto, California 94304","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057180795","display_name":"Robin Hastings","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Hastings","raw_affiliation_strings":["DNAX Research Institute, Palo Alto, California 94304"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DNAX Research Institute, Palo Alto, California 94304","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015718586","display_name":"John F. Kearney","orcid":"https://orcid.org/0000-0003-2569-2560","observed_orcids":["https://orcid.org/0000-0003-2569-2560"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Kearney","raw_affiliation_strings":["DNAX Research Institute, Palo Alto, California 94304"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DNAX Research Institute, Palo Alto, California 94304","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111964197","display_name":"M Howard","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Howard","raw_affiliation_strings":["DNAX Research Institute, Palo Alto, California 94304"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DNAX Research Institute, Palo Alto, California 94304","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":9.1935,"has_fulltext":false,"cited_by_count":197,"citation_normalized_percentile":{"value":0.98545869,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"175","issue":"5","first_page":"1213","last_page":"1220"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ly-1-b-cells","display_name":"Ly-1 B cells","score":0.8830000162124634},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.9279999732971191},{"id":"https://openalex.org/keywords/anti-il-10-antibody","display_name":"anti-IL-10 antibody","score":0.8429999947547913},{"id":"https://openalex.org/keywords/b-cell-depletion","display_name":"B-cell depletion","score":0.8519999980926514},{"id":"https://openalex.org/keywords/b-cell-development","display_name":"B cell development","score":0.6269999742507935},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.9380000233650208},{"id":"https://openalex.org/keywords/autocrine-growth-factor","display_name":"autocrine growth factor","score":0.6399999856948853},{"id":"https://openalex.org/keywords/peritoneal-b-cells","display_name":"peritoneal B cells","score":0.7570000290870667},{"id":"https://openalex.org/keywords/immunoglobulin-m","display_name":"immunoglobulin M","score":0.8309999704360962},{"id":"https://openalex.org/keywords/antibody-response","display_name":"antibody response","score":0.6970000267028809},{"id":"https://openalex.org/keywords/t-independent-antigens","display_name":"T-independent antigens","score":0.578000009059906},{"id":"https://openalex.org/keywords/b-cell-subsets","display_name":"B cell subsets","score":0.31299999356269836}],"concepts":[{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.7135171890258789},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6484689712524414},{"id":"https://openalex.org/C128240485","wikidata":"https://www.wikidata.org/wiki/Q786998","display_name":"Autocrine signalling","level":3,"score":0.6083118915557861},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.5995973348617554},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5969550013542175},{"id":"https://openalex.org/C2776833585","wikidata":"https://www.wikidata.org/wiki/Q7187582","display_name":"Phosphorylcholine","level":2,"score":0.5854319334030151},{"id":"https://openalex.org/C49382859","wikidata":"https://www.wikidata.org/wiki/Q286498","display_name":"Lymphokine","level":3,"score":0.5591950416564941},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5325913429260254},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4851253926753998},{"id":"https://openalex.org/C145558887","wikidata":"https://www.wikidata.org/wiki/Q3832893","display_name":"B-1 cell","level":5,"score":0.4817042946815491},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.48095980286598206},{"id":"https://openalex.org/C2776727803","wikidata":"https://www.wikidata.org/wiki/Q1496686","display_name":"Keyhole limpet hemocyanin","level":3,"score":0.4408002197742462},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.3973965644836426},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.3402952551841736},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2768726646900177},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.25600481033325195},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000906","descriptor_name":"Antibodies","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000945","descriptor_name":"Antigens, Differentiation, T-Lymphocyte","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007075","descriptor_name":"Immunoglobulin M","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D007274","descriptor_name":"Injections, Intraperitoneal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008809","descriptor_name":"Mice, Inbred C3H","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009500","descriptor_name":"Neutralization Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011948","descriptor_name":"Receptors, Antigen, T-Cell","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017252","descriptor_name":"CD3 Complex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1084/jem.175.5.1213","doi":"https://doi.org/10.1084/jem.175.5.1213","is_oa":false,"landing_page_url":"https://doi.org/10.1084/jem.175.5.1213","pdf_url":null,"source":{"id":"https://openalex.org/S22947807","display_name":"The Journal of Experimental Medicine","issn_l":"0022-1007","issn":["0022-1007","1540-9538"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2119200","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2119200","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},{"id":"pmid:1533240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1533240","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of experimental medicine","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2119200","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2119200","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Exp Med","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1289666709","display_name":null,"funder_award_id":"AI14782","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G721130862","display_name":"CELL DIFFERENTIATION STUDIES IN CANCER IMMUNOBIOLOGY","funder_award_id":"P01AI030879","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000883787","display_name":"Comprehensive Cancer Center Support Grant","funder_award_id":"P30CA013148","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W113842083","https://openalex.org/W163125452","https://openalex.org/W1490657112","https://openalex.org/W1494254017","https://openalex.org/W1529773650","https://openalex.org/W1545388095","https://openalex.org/W1604235633","https://openalex.org/W1654639198","https://openalex.org/W1658552097","https://openalex.org/W1658761436","https://openalex.org/W1966844155","https://openalex.org/W1973170041","https://openalex.org/W1980420110","https://openalex.org/W1981863728","https://openalex.org/W1992707199","https://openalex.org/W1997486720","https://openalex.org/W1999246265","https://openalex.org/W2000107365","https://openalex.org/W2001863306","https://openalex.org/W2002209097","https://openalex.org/W2003955301","https://openalex.org/W2005246059","https://openalex.org/W2007765422","https://openalex.org/W2016190951","https://openalex.org/W2021916493","https://openalex.org/W2038434279","https://openalex.org/W2040451630","https://openalex.org/W2040619664","https://openalex.org/W2054629245","https://openalex.org/W2057124584","https://openalex.org/W2060546545","https://openalex.org/W2060912271","https://openalex.org/W2078547612","https://openalex.org/W2079316032","https://openalex.org/W2080059202","https://openalex.org/W2084990572","https://openalex.org/W2103516617","https://openalex.org/W2108569073","https://openalex.org/W2114146017","https://openalex.org/W2123511115","https://openalex.org/W2126411195","https://openalex.org/W2128587758","https://openalex.org/W2137266284","https://openalex.org/W2144225361","https://openalex.org/W2146451383","https://openalex.org/W2150195134","https://openalex.org/W2191654227"],"related_works":["https://openalex.org/W2073310345","https://openalex.org/W2119811271","https://openalex.org/W2027094929","https://openalex.org/W2070615015","https://openalex.org/W2016486423","https://openalex.org/W2027749164","https://openalex.org/W1980751204","https://openalex.org/W1994641644","https://openalex.org/W4404175166","https://openalex.org/W2162743131"],"abstract_inverted_index":{"Ly-1":[0,58,90,127,167,198,212,223],"B":[1,22,59,91,122,128,135,153,168,199,213,224],"cells":[2,23,123,136,200,235],"have":[3,13],"the":[4,25,35,44,126,157,194,231,237],"distinctive":[5],"property":[6],"of":[7,27,34,70,113,137,166,177,188,196,211,230,233],"continuous":[8],"self-replenishment":[9],"and,":[10],"as":[11,49,208],"we":[12,61],"shown":[14],"previously,":[15],"can":[16],"be":[17,173],"further":[18,228],"distinguished":[19],"from":[20,65],"conventional":[21,133],"on":[24],"basis":[26],"greatly":[28,94],"elevated":[29],"constitutive":[30],"and":[31,100,148,156,216],"inducible":[32],"production":[33],"recently":[36],"described":[37],"cytokine":[38],"interleukin":[39],"10":[40],"(IL-10).":[41],"To":[42],"test":[43],"possibility":[45],"that":[46,78],"IL-10":[47,207],"acts":[48],"either":[50],"an":[51],"autocrine":[52],"or":[53,116],"paracrine":[54],"growth":[55],"factor":[56],"for":[57,119],"cells,":[60,92,225],"treated":[62,84],"mice":[63,139],"continuously":[64],"birth":[66],"to":[67,103,110,144,152,172,175,220],"8":[68],"wk":[69],"age":[71],"with":[72,142],"a":[73,209,218],"monoclonal":[74],"rat":[75],"IgM":[76],"antibody":[77,108],"specifically":[79,221],"neutralizes":[80],"mouse":[81],"IL-10.":[82],"Mice":[83],"in":[85,106,125,149,183,201,236],"this":[86],"way":[87],"lacked":[88],"peritoneal-resident":[89,197],"contained":[93],"reduced":[95],"serum":[96],"immunoglobulin":[97],"M":[98],"levels,":[99],"were":[101,140],"unable":[102],"generate":[104],"significant":[105],"vivo":[107],"responses":[109],"intraperitoneal":[111],"injections":[112],"alpha":[114],"1,3-dextran":[115],"phosphorylcholine,":[117],"antigens":[118],"which":[120],"specific":[121],"reside":[124],"cell":[129,154,169,214],"subset.":[130],"In":[131],"contrast,":[132],"splenic":[134],"anti-IL-10-treated":[138,184],"normal":[141],"respect":[143],"total":[145],"numbers,":[146],"phenotype,":[147],"vitro":[150],"responsiveness":[151],"mitogens":[155],"thymus-dependent":[158],"antigen":[159],"trinitrophenyl-keyhole":[160],"limpet":[161],"hemocyanin":[162],"(TNP-KLH).":[163],"The":[164],"mechanism":[165],"depletion":[170],"appeared":[171],"related":[174],"elevation":[176],"endogenous":[178],"interferon":[179],"gamma":[180],"(IFN-gamma)":[181],"levels":[182],"mice,":[185],"since":[186],"coadministration":[187],"neutralizing":[189],"anti-IFN-gamma":[190],"antibodies":[191],"substantially":[192],"restored":[193],"number":[195],"these":[202,234],"mice.":[203],"These":[204],"results":[205],"implicate":[206],"regulator":[210],"development,":[215],"identify":[217],"procedure":[219],"deplete":[222],"thereby":[226],"allowing":[227],"evaluation":[229],"role":[232],"immune":[238],"system.":[239]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}