{"id":"https://openalex.org/W2153641732","doi":"https://doi.org/10.1016/s1470-2045(12)70372-8","title":"Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study","display_name":"Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study","publication_year":2012,"publication_date":"2012-10-08","ids":{"openalex":"https://openalex.org/W2153641732","doi":"https://doi.org/10.1016/s1470-2045(12)70372-8","mag":"2153641732","pmid":"https://pubmed.ncbi.nlm.nih.gov/23059046","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4878433"},"language":"en","primary_location":{"id":"doi:10.1016/s1470-2045(12)70372-8","doi":"https://doi.org/10.1016/s1470-2045(12)70372-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1470-2045(12)70372-8","pdf_url":null,"source":{"id":"https://openalex.org/S116900674","display_name":"The Lancet Oncology","issn_l":"1470-2045","issn":["1470-2045","1474-5488"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4878433","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072116005","display_name":"David Olmos","orcid":"https://orcid.org/0000-0002-7003-4826","observed_orcids":["https://orcid.org/0000-0002-7003-4826"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]},{"id":"https://openalex.org/I4210089594","display_name":"Spanish National Cancer Research Centre","ror":"https://ror.org/00bvhmc43","country_code":"ES","type":"facility","lineage":["https://openalex.org/I4210089594"]}],"countries":["ES","GB"],"is_corresponding":false,"raw_author_name":"David Olmos","raw_affiliation_strings":["Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","Clinical Research Programme, Spanish National Cancer Research Centre, Madrid, Spain","Section of Medicine, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","institution_ids":["https://openalex.org/I1325846038"]},{"raw_affiliation_string":"Clinical Research Programme, Spanish National Cancer Research Centre, Madrid, Spain","institution_ids":["https://openalex.org/I4210089594"]},{"raw_affiliation_string":"Section of Medicine, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088971353","display_name":"Daniel S. Brewer","orcid":"https://orcid.org/0000-0003-4753-9794","observed_orcids":["https://orcid.org/0000-0003-4753-9794"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Daniel Brewer","raw_affiliation_strings":["Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109994256","display_name":"Jeremy Clark","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jeremy Clark","raw_affiliation_strings":["Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036310901","display_name":"Daniel Costin Danila","orcid":"https://orcid.org/0000-0002-7647-0741","observed_orcids":["https://orcid.org/0000-0002-7647-0741"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405269141","display_name":"Sidney Kimmel Center for Prostate and Urologic Cancers","ror":"https://ror.org/037e5pc19","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405269141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel C Danila","raw_affiliation_strings":["Department of Medicine, Weill Cornell College of Medicine, New York, NY, USA","Genitourinary Oncology Service, Department of Medicine, Sidney Kimmel Center for Prostate and Urologic Cancers, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Weill Cornell College of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Genitourinary Oncology Service, Department of Medicine, Sidney Kimmel Center for Prostate and Urologic Cancers, New York, NY, USA","institution_ids":["https://openalex.org/I4405269141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101420072","display_name":"Chris C. Parker","orcid":"https://orcid.org/0000-0001-6512-124X","observed_orcids":["https://orcid.org/0000-0001-6512-124X","https://orcid.org/0000-0001-7724-9486"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Chris Parker","raw_affiliation_strings":["Academic Urology Unit, The Royal Marsden NHS Foundation Trust, Sutton and London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academic Urology Unit, The Royal Marsden NHS Foundation Trust, Sutton and London, UK","institution_ids":["https://openalex.org/I1325846038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000156180","display_name":"Gerhardt Attard","orcid":"https://orcid.org/0000-0002-4811-7983","observed_orcids":["https://orcid.org/0000-0002-4811-7983"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gerhardt Attard","raw_affiliation_strings":["Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","Section of Medicine, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","institution_ids":["https://openalex.org/I1325846038"]},{"raw_affiliation_string":"Section of Medicine, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012521956","display_name":"Martin Fleisher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Fleisher","raw_affiliation_strings":["Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013567386","display_name":"Alison H. M. Reid","orcid":"https://orcid.org/0000-0001-8567-4941","observed_orcids":["https://orcid.org/0000-0001-8567-4941"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alison HM Reid","raw_affiliation_strings":["Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","Section of Medicine, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","institution_ids":["https://openalex.org/I1325846038"]},{"raw_affiliation_string":"Section of Medicine, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077861800","display_name":"Elena Castro","orcid":"https://orcid.org/0000-0002-3691-6454","observed_orcids":["https://orcid.org/0000-0002-3691-6454"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Elena Castro","raw_affiliation_strings":["Academic Urology Unit, The Royal Marsden NHS Foundation Trust, Sutton and London, UK","Cancer Genetics Department, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academic Urology Unit, The Royal Marsden NHS Foundation Trust, Sutton and London, UK","institution_ids":["https://openalex.org/I1325846038"]},{"raw_affiliation_string":"Cancer Genetics Department, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064026461","display_name":"Shahneen Kaur Sandhu","orcid":"https://orcid.org/0000-0002-8660-4475","observed_orcids":["https://orcid.org/0000-0002-8660-4475"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Shahneen K Sandhu","raw_affiliation_strings":["Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","Section of Medicine, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","institution_ids":["https://openalex.org/I1325846038"]},{"raw_affiliation_string":"Section of Medicine, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038558246","display_name":"Lorraine Barwell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800373718","display_name":"Beatson West of Scotland Cancer Centre","ror":"https://ror.org/03pp86w19","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800373718"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lorraine Barwell","raw_affiliation_strings":["The Beatson West of Scotland Cancer Centre, Glasgow, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Beatson West of Scotland Cancer Centre, Glasgow, UK","institution_ids":["https://openalex.org/I2800373718"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046200187","display_name":"Nikhil Babu Oommen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nikhil Babu Oommen","raw_affiliation_strings":["Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","institution_ids":["https://openalex.org/I1325846038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085732690","display_name":"Suzanne Carreira","orcid":"https://orcid.org/0000-0002-5077-5379","observed_orcids":["https://orcid.org/0000-0002-5077-5379"]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Suzanne Carreira","raw_affiliation_strings":["Section of Medicine, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Medicine, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031310463","display_name":"Charles G. Drake","orcid":"https://orcid.org/0000-0001-9610-3677","observed_orcids":["https://orcid.org/0000-0001-9610-3677"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210164401","display_name":"Sidney Kimmel Comprehensive Cancer Center","ror":"https://ror.org/05m5b8x20","country_code":"US","type":"facility","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210164401"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles G Drake","raw_affiliation_strings":["James Buchanan Brady Urological Institute, Sidney Kimmel Comprehensive Cancer Centre, Johns Hopkins University, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"James Buchanan Brady Urological Institute, Sidney Kimmel Comprehensive Cancer Centre, Johns Hopkins University, Baltimore, MD, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210164401"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048796030","display_name":"Robert J. Jones","orcid":"https://orcid.org/0000-0002-2904-6980","observed_orcids":["https://orcid.org/0000-0002-2904-6980","https://orcid.org/0000-0003-0759-8968"]},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Jones","raw_affiliation_strings":["Institute of Cancer Sciences, University of Glasgow, Glasgow, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cancer Sciences, University of Glasgow, Glasgow, UK","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104097760","display_name":"Colin S. Cooper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Colin S Cooper","raw_affiliation_strings":["Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072850546","display_name":"Howard I. Scher","orcid":"https://orcid.org/0000-0002-6791-9324","observed_orcids":["https://orcid.org/0000-0002-6791-9324"]},"institutions":[{"id":"https://openalex.org/I4387153466","display_name":"Weill Cornell Medicine","ror":"https://ror.org/02r109517","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4387153466"]},{"id":"https://openalex.org/I4405269141","display_name":"Sidney Kimmel Center for Prostate and Urologic Cancers","ror":"https://ror.org/037e5pc19","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4405269141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Howard I Scher","raw_affiliation_strings":["Department of Medicine, Weill Cornell College of Medicine, New York, NY, USA","Genitourinary Oncology Service, Department of Medicine, Sidney Kimmel Center for Prostate and Urologic Cancers, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Weill Cornell College of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I4387153466"]},{"raw_affiliation_string":"Genitourinary Oncology Service, Department of Medicine, Sidney Kimmel Center for Prostate and Urologic Cancers, New York, NY, USA","institution_ids":["https://openalex.org/I4405269141"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072378199","display_name":"Johann Sebastian De Bono","orcid":"https://orcid.org/0000-0002-2034-595X","observed_orcids":["https://orcid.org/0000-0002-2034-595X"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I142947616","display_name":"Institute of Cancer Research","ror":"https://ror.org/043jzw605","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I142947616"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Johann S de Bono","raw_affiliation_strings":["Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","Section of Medicine, The Institute of Cancer Research, Sutton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Development Unit, The Royal Marsden NHS Foundation Trust, Sutton, UK","institution_ids":["https://openalex.org/I1325846038"]},{"raw_affiliation_string":"Section of Medicine, The Institute of Cancer Research, Sutton, UK","institution_ids":["https://openalex.org/I142947616"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5072378199"],"corresponding_institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I142947616"],"apc_list":{"value":7280,"currency":"USD","value_usd":7280},"apc_paid":null,"fwci":12.8745,"has_fulltext":false,"cited_by_count":112,"citation_normalized_percentile":{"value":0.99102589,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"13","issue":"11","first_page":"1114","last_page":"1124"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/castration-resistant-prostate-cancer","display_name":"castration-resistant prostate cancer","score":0.9860000014305115},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9459999799728394},{"id":"https://openalex.org/keywords/metastatic-prostate-cancer","display_name":"metastatic prostate cancer","score":0.734000027179718},{"id":"https://openalex.org/keywords/active-surveillance","display_name":"active surveillance","score":0.6259999871253967},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9430000185966492},{"id":"https://openalex.org/keywords/patient-stratification","display_name":"patient stratification","score":0.41999998688697815},{"id":"https://openalex.org/keywords/whole-blood-rna","display_name":"whole blood RNA","score":0.36000001430511475},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.5149999856948853},{"id":"https://openalex.org/keywords/treatment-response-prediction","display_name":"treatment response prediction","score":0.4580000042915344},{"id":"https://openalex.org/keywords/drug-discovery-targets","display_name":"drug discovery targets","score":0.3700000047683716},{"id":"https://openalex.org/keywords/qrt-pcr","display_name":"qRT-PCR","score":0.7360000014305115}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7763203382492065},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.7026540040969849},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5773159265518188},{"id":"https://openalex.org/C2779256933","wikidata":"https://www.wikidata.org/wiki/Q58929","display_name":"Castration","level":3,"score":0.5257509350776672},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.5107815265655518},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46846315264701843},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45439696311950684},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4176548719406128},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.41648605465888977},{"id":"https://openalex.org/C2776291640","wikidata":"https://www.wikidata.org/wiki/Q2912517","display_name":"Value (mathematics)","level":2,"score":0.4123510718345642},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.33697086572647095},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.32244205474853516},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31684303283691406},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16281592845916748},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.10999837517738342},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0815337598323822},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.06799200177192688},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.054500699043273926},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002369","descriptor_name":"Castration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016019","descriptor_name":"Survival Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060787","descriptor_name":"Neoplasm Grading","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/s1470-2045(12)70372-8","doi":"https://doi.org/10.1016/s1470-2045(12)70372-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1470-2045(12)70372-8","pdf_url":null,"source":{"id":"https://openalex.org/S116900674","display_name":"The Lancet Oncology","issn_l":"1470-2045","issn":["1470-2045","1474-5488"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Oncology","raw_type":"journal-article"},{"id":"pmid:23059046","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23059046","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet. Oncology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4878433","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4878433","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Lancet Oncol","raw_type":"Text"},{"id":"pmh:oai:eprints.gla.ac.uk:71191","doi":null,"is_oa":false,"landing_page_url":"http://eprints.gla.ac.uk/71191/","pdf_url":null,"source":{"id":"https://openalex.org/S4210235606","display_name":"ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)","issn_l":"2622-8912","issn":["2622-8912","2622-8920"],"is_oa":false,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/I4405259220","host_organization_name":"Institut Agama Islam Negeri Langsa","host_organization_lineage":["https://openalex.org/I4405259220"],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Articles"},{"id":"pmh:oai:ueaeprints.uea.ac.uk:46120","doi":null,"is_oa":false,"landing_page_url":"https://ueaeprints.uea.ac.uk/id/eprint/46120/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400384","display_name":"UEA Digital Repository (University of East Anglia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1118541","host_organization_name":"University of East Anglia","host_organization_lineage":["https://openalex.org/I1118541"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4878433","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4878433","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Lancet Oncol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2519382346","display_name":null,"funder_award_id":"CL-2008-22-001","funder_id":"https://openalex.org/F4320319990","funder_display_name":"National Institute for Health and Care Research"},{"id":"https://openalex.org/G4874885190","display_name":null,"funder_award_id":"13239","funder_id":"https://openalex.org/F4320319985","funder_display_name":"Cancer Research UK"},{"id":"https://openalex.org/G9000911005","display_name":"Regional Oncology Research Center","funder_award_id":"P30CA006973","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320306163","display_name":"Prostate Cancer Foundation","ror":"https://ror.org/01npwtv09"},{"id":"https://openalex.org/F4320315585","display_name":"Commonwealth Foundation for Cancer Research Foundation","ror":null},{"id":"https://openalex.org/F4320319985","display_name":"Cancer Research UK","ror":"https://ror.org/054225q67"},{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320325516","display_name":"Sociedad Espa\u00f1ola de Oncolog\u00eda M\u00e9dica","ror":"https://ror.org/05r1zgk22"},{"id":"https://openalex.org/F4320335322","display_name":"European Regional Development Fund","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1544923801","https://openalex.org/W1599507531","https://openalex.org/W1707889259","https://openalex.org/W1899615101","https://openalex.org/W1917241559","https://openalex.org/W1942950965","https://openalex.org/W1963853602","https://openalex.org/W1969105938","https://openalex.org/W1979410617","https://openalex.org/W1980648047","https://openalex.org/W1986870905","https://openalex.org/W1987424755","https://openalex.org/W1991674557","https://openalex.org/W1998096683","https://openalex.org/W2002995168","https://openalex.org/W2013432209","https://openalex.org/W2016538215","https://openalex.org/W2017631280","https://openalex.org/W2021223376","https://openalex.org/W2049984303","https://openalex.org/W2053970131","https://openalex.org/W2054541484","https://openalex.org/W2081479079","https://openalex.org/W2089931951","https://openalex.org/W2095275496","https://openalex.org/W2096865083","https://openalex.org/W2104901100","https://openalex.org/W2112251186","https://openalex.org/W2112564453","https://openalex.org/W2128173047","https://openalex.org/W2131456094","https://openalex.org/W2143717212","https://openalex.org/W2147625347","https://openalex.org/W2158732421","https://openalex.org/W2163814095","https://openalex.org/W2165613795","https://openalex.org/W2331148235","https://openalex.org/W2597632520","https://openalex.org/W2911964244"],"related_works":["https://openalex.org/W3000028180","https://openalex.org/W2567994971","https://openalex.org/W4231040818","https://openalex.org/W2003136111","https://openalex.org/W2147011132","https://openalex.org/W4324136744","https://openalex.org/W1990855596","https://openalex.org/W1986870905","https://openalex.org/W2589289286","https://openalex.org/W2590930662"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":16},{"year":2013,"cited_by_count":15},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}