{"id":"https://openalex.org/W2153456482","doi":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","title":"Genetic variation in epigenetic inheritance of ribosomal RNA gene methylation in Arabidopsis","display_name":"Genetic variation in epigenetic inheritance of ribosomal RNA gene methylation in Arabidopsis","publication_year":2004,"publication_date":"2004-12-22","ids":{"openalex":"https://openalex.org/W2153456482","doi":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","mag":"2153456482","pmid":"https://pubmed.ncbi.nlm.nih.gov/15686517"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-313x.2004.02317.x","doi":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2004.02317.x","source":{"id":"https://openalex.org/S67862205","display_name":"The Plant Journal","issn_l":"0960-7412","issn":["0960-7412","1365-313X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2004.02317.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054176539","display_name":"Nicole C. Riddle","orcid":"https://orcid.org/0000-0003-1827-9145","observed_orcids":["https://orcid.org/0000-0003-1827-9145"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole C. Riddle","raw_affiliation_strings":["Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA","Present address: Division of Biological Sciences, University of Missouri \u2013 Columbia, 117 Tucker Hall, Columbia, MO 65211, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Present address: Division of Biological Sciences, University of Missouri \u2013 Columbia, 117 Tucker Hall, Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049853388","display_name":"Eric J. Richards","orcid":"https://orcid.org/0000-0002-8665-7470","observed_orcids":["https://orcid.org/0000-0002-8665-7470"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eric J. Richards","raw_affiliation_strings":["Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA","Division of Biological Sciences, University of Missouri -Columbia, 117 Tucker Hall, Columbia, MO 65211, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Division of Biological Sciences, University of Missouri -Columbia, 117 Tucker Hall, Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I76835614"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5049853388"],"corresponding_institution_ids":["https://openalex.org/I204465549","https://openalex.org/I76835614"],"apc_list":{"value":5450,"currency":"USD","value_usd":5450},"apc_paid":null,"fwci":1.1836,"has_fulltext":true,"cited_by_count":50,"citation_normalized_percentile":{"value":0.75839163,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"41","issue":"4","first_page":"524","last_page":"532"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.061900001019239426,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.012199999764561653,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetic-inheritance","display_name":"epigenetic inheritance","score":0.9890000224113464},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.8830000162124634},{"id":"https://openalex.org/keywords/ribosomal-dna","display_name":"ribosomal DNA","score":0.8410000205039978},{"id":"https://openalex.org/keywords/nucleolar-organizer-regions","display_name":"nucleolar organizer regions","score":0.9369999766349792},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8679999709129333},{"id":"https://openalex.org/keywords/interspecific-hybridization","display_name":"interspecific hybridization","score":0.6290000081062317},{"id":"https://openalex.org/keywords/epistasis","display_name":"epistasis","score":0.7590000033378601},{"id":"https://openalex.org/keywords/mendelian-segregation","display_name":"Mendelian segregation","score":0.6050000190734863}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9027189612388611},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.7188949584960938},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6431370973587036},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.6293424367904663},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.5237985849380493},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.4220486283302307},{"id":"https://openalex.org/C163002167","wikidata":"https://www.wikidata.org/wiki/Q7277124","display_name":"RNA-Directed DNA Methylation","level":5,"score":0.41805920004844666},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3740122318267822},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.14435261487960815},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003433","descriptor_name":"Crosses, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012335","descriptor_name":"RNA, Ribosomal","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018749","descriptor_name":"RNA, Plant","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019175","descriptor_name":"DNA Methylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D044127","descriptor_name":"Epigenesis, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-313x.2004.02317.x","doi":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2004.02317.x","source":{"id":"https://openalex.org/S67862205","display_name":"The Plant Journal","issn_l":"0960-7412","issn":["0960-7412","1365-313X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant Journal","raw_type":"journal-article"},{"id":"pmid:15686517","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15686517","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant journal : for cell and molecular biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1365-313x.2004.02317.x","doi":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-313x.2004.02317.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2004.02317.x","source":{"id":"https://openalex.org/S67862205","display_name":"The Plant Journal","issn_l":"0960-7412","issn":["0960-7412","1365-313X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2549475946","display_name":"Arabidopsis DDM1: DNA Methylation and Epigenetic Stability","funder_award_id":"9985348","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320309374","display_name":"Ohio State University","ror":"https://ror.org/00rs6vg23"},{"id":"https://openalex.org/F4320322266","display_name":"Ministry of Agriculture, Forestry and Fisheries","ror":"https://ror.org/02zdz1m23"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2153456482.pdf","grobid_xml":"https://content.openalex.org/works/W2153456482.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W288906629","https://openalex.org/W1534122645","https://openalex.org/W1556385076","https://openalex.org/W1635316621","https://openalex.org/W1821797507","https://openalex.org/W1822731522","https://openalex.org/W1843115240","https://openalex.org/W1859788221","https://openalex.org/W1889938952","https://openalex.org/W1895459516","https://openalex.org/W1932735166","https://openalex.org/W1960142378","https://openalex.org/W1963657604","https://openalex.org/W1975231696","https://openalex.org/W1978661900","https://openalex.org/W1980871497","https://openalex.org/W1991580604","https://openalex.org/W2013652801","https://openalex.org/W2018057184","https://openalex.org/W2018220730","https://openalex.org/W2029003608","https://openalex.org/W2033813404","https://openalex.org/W2033942106","https://openalex.org/W2034617842","https://openalex.org/W2041844160","https://openalex.org/W2043622843","https://openalex.org/W2052639867","https://openalex.org/W2052668971","https://openalex.org/W2053743939","https://openalex.org/W2057354082","https://openalex.org/W2103198032","https://openalex.org/W2104534767","https://openalex.org/W2109337696","https://openalex.org/W2112833394","https://openalex.org/W2113170874","https://openalex.org/W2119577108","https://openalex.org/W2122027021","https://openalex.org/W2134656290","https://openalex.org/W2139288600","https://openalex.org/W2156884959","https://openalex.org/W2166483716","https://openalex.org/W2175849508","https://openalex.org/W2176142414","https://openalex.org/W2288319580","https://openalex.org/W2292421259","https://openalex.org/W2418140292","https://openalex.org/W2576734941"],"related_works":["https://openalex.org/W2104534767","https://openalex.org/W1998573472","https://openalex.org/W7100891696","https://openalex.org/W2536881517","https://openalex.org/W1985624299","https://openalex.org/W1985345150","https://openalex.org/W7098853603","https://openalex.org/W2080594632","https://openalex.org/W2054854463","https://openalex.org/W2021367660"],"abstract_inverted_index":{"We":[0],"investigated":[1],"the":[2,13,28,33,38,57,64,78,85,95,104,107,116,129,133,138,167,173,197,216],"fidelity":[3],"of":[4,12,32,69,106,141,166,199,218,221],"epigenetic":[5,139,222],"inheritance":[6,105,140,198],"in":[7,46,172],"crosses":[8,55,76],"between":[9,56,77,115,132],"three":[10],"accessions":[11],"flowering":[14],"plant":[15],"Arabidopsis":[16],"thaliana":[17],"(Canary":[18],"Islands,":[19,22],"Cape":[20,81],"Verde":[21,82],"and":[23,44,48,63,80,119],"Columbia).":[24],"Specifically,":[25],"we":[26],"examined":[27],"cytosine":[29,86,125,201],"methylation":[30,60,87,98,126,143,169,183,202],"content":[31,88,127,184],"ribosomal":[34],"RNA":[35],"genes":[36],"at":[37,128,204],"two":[39,65,108],"nucleolus":[40],"organizer":[41],"regions":[42],"(NOR2":[43],"NOR4)":[45],"F1":[47],"F2":[49,149],"hybrid":[50,113],"individuals":[51,114,150],"derived":[52,151],"from":[53,148,152],"reciprocal":[54],"high":[58,96],"NOR":[59,73,97,110,168,182,205],"strain,":[61],"Columbia,":[62],"other":[66],"accessions,":[67],"both":[68],"which":[70],"have":[71],"less":[72],"methylation.":[74],"In":[75],"Columbia":[79,120,157],"Islands":[83,118,155],"strains,":[84],"segregated":[89],"as":[90],"an":[91],"additive":[92],"Mendelian":[93],"trait:":[94],"state":[99],"was":[100],"tightly":[101],"associated":[102],"with":[103,137,191],"Columbia-derived":[109],"loci.":[111],"First-generation":[112],"Canary":[117,154],"strains":[121],"also":[122],"showed":[123],"a":[124,153,177,187],"NORs":[130],"intermediate":[131],"parental":[134,142],"values,":[135],"consistent":[136],"patterns.":[144],"Interestingly,":[145],"mapping":[146],"data":[147],"x":[156],"cross":[158],"revealed":[159],"that":[160,196],"NOR2":[161],"accounted":[162],"for":[163],"nearly":[164],"all":[165],"variation":[170],"segregating":[171],"population.":[174],"NOR4":[175],"retains":[176],"significant":[178],"effect":[179],"on":[180],"total":[181],"only":[185],"through":[186],"complex":[188],"epistatic":[189],"interaction":[190],"NOR2.":[192],"Our":[193],"results":[194],"indicate":[195],"differential":[200],"states":[203],"loci":[206],"can":[207],"be":[208],"modified":[209],"by":[210],"their":[211],"genetic":[212,219],"context,":[213],"opening":[214],"up":[215],"possibility":[217],"dissection":[220],"inheritance.":[223]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}