{"id":"https://openalex.org/W2153406283","doi":"https://doi.org/10.1046/j.1365-2281.1997.00062.x","title":"Stiffness of the common carotid artery in healthy 50\u2010year\u2010old subjects","display_name":"Stiffness of the common carotid artery in healthy 50\u2010year\u2010old subjects","publication_year":1997,"publication_date":"1997-10-01","ids":{"openalex":"https://openalex.org/W2153406283","doi":"https://doi.org/10.1046/j.1365-2281.1997.00062.x","mag":"2153406283","pmid":"https://pubmed.ncbi.nlm.nih.gov/9413644"},"language":"en","primary_location":{"id":"doi:10.1046/j.1365-2281.1997.00062.x","doi":"https://doi.org/10.1046/j.1365-2281.1997.00062.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2281.1997.00062.x","pdf_url":null,"source":{"id":"https://openalex.org/S58807641","display_name":"Clinical Physiology","issn_l":"0144-5979","issn":["0144-5979","1365-2281"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070950495","display_name":"Tommy Jonason","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107839","display_name":"V\u00e4ster\u00e5s Municipality","ror":"https://ror.org/01rrc6194","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210107839"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"T. Jonason","raw_affiliation_strings":["Department of Clinical Physiology, Central Hospital, V\u00e4ster\u00e5s, Sweden","Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Physiology, Central Hospital, V\u00e4ster\u00e5s, Sweden","institution_ids":["https://openalex.org/I4210107839"]},{"raw_affiliation_string":"Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,","institution_ids":["https://openalex.org/I4210107839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005848930","display_name":"E. Henrikssen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107839","display_name":"V\u00e4ster\u00e5s Municipality","ror":"https://ror.org/01rrc6194","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210107839"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"E. Henrikssen","raw_affiliation_strings":["Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,","institution_ids":["https://openalex.org/I4210107839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030161791","display_name":"Toomas Kangro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107839","display_name":"V\u00e4ster\u00e5s Municipality","ror":"https://ror.org/01rrc6194","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210107839"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"T. Kangro","raw_affiliation_strings":["Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,","institution_ids":["https://openalex.org/I4210107839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037674191","display_name":"Helena Nilsson","orcid":"https://orcid.org/0000-0001-7315-1166","observed_orcids":["https://orcid.org/0000-0001-7315-1166"]},"institutions":[{"id":"https://openalex.org/I4210107839","display_name":"V\u00e4ster\u00e5s Municipality","ror":"https://ror.org/01rrc6194","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210107839"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"H. Nilsson","raw_affiliation_strings":["Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,","institution_ids":["https://openalex.org/I4210107839"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110231931","display_name":"B. Vessby","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123387679","display_name":"Uppsala University","ror":"https://ror.org/048a87296","country_code":"SE","type":"education","lineage":["https://openalex.org/I123387679"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"B. Vessby","raw_affiliation_strings":["Department of Geriatrics, University of Uppsala, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatrics, University of Uppsala, Sweden","institution_ids":["https://openalex.org/I123387679"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005573008","display_name":"Ivar Ringqvist","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210107839","display_name":"V\u00e4ster\u00e5s Municipality","ror":"https://ror.org/01rrc6194","country_code":"SE","type":"government","lineage":["https://openalex.org/I4210107839"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"I. Ringqvist","raw_affiliation_strings":["Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Research and Clinical Physiology, Central Hospital, Va\u0308stera\u030as, Sweden,","institution_ids":["https://openalex.org/I4210107839"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070950495"],"corresponding_institution_ids":["https://openalex.org/I4210107839"],"apc_list":null,"apc_paid":null,"fwci":0.7656,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.75649295,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"17","issue":"6","first_page":"569","last_page":"577"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11366","display_name":"Elasticity and Material Modeling","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carotid-stiffness","display_name":"carotid artery stiffness","score":0.8889999985694885},{"id":"https://openalex.org/keywords/common-carotid-artery","display_name":"common carotid artery","score":0.8579999804496765},{"id":"https://openalex.org/keywords/atherosclerosis-risk-factors","display_name":"atherosclerosis risk factors","score":0.9120000004768372},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8420000076293945},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.6669999957084656},{"id":"https://openalex.org/keywords/pack-years","display_name":"pack-years","score":0.8109999895095825},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.8019999861717224},{"id":"https://openalex.org/keywords/ldl-hdl-ratio","display_name":"LDL/HDL ratio","score":0.9449999928474426},{"id":"https://openalex.org/keywords/arterial-diameter","display_name":"arterial diameter","score":0.8730000257492065},{"id":"https://openalex.org/keywords/arterial-elasticity","display_name":"arterial elasticity","score":0.4230000078678131},{"id":"https://openalex.org/keywords/middle-aged-adults","display_name":"middle-aged adults","score":0.6859999895095825}],"concepts":[{"id":"https://openalex.org/C2775850156","wikidata":"https://www.wikidata.org/wiki/Q4797538","display_name":"Arterial stiffness","level":3,"score":0.8529307246208191},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.82431960105896},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.706928551197052},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.669975757598877},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.4639114737510681},{"id":"https://openalex.org/C2776820930","wikidata":"https://www.wikidata.org/wiki/Q9655","display_name":"Artery","level":2,"score":0.4437131881713867},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.44216716289520264},{"id":"https://openalex.org/C2987047532","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Carotid arteries","level":2,"score":0.4235299825668335},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3425702452659607},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.34023916721343994}],"mesh":[{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001161","descriptor_name":"Arteriosclerosis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D002784","descriptor_name":"Cholesterol","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D004548","descriptor_name":"Elasticity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017536","descriptor_name":"Carotid Artery, Common","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D017536","descriptor_name":"Carotid Artery, Common","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1365-2281.1997.00062.x","doi":"https://doi.org/10.1046/j.1365-2281.1997.00062.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1365-2281.1997.00062.x","pdf_url":null,"source":{"id":"https://openalex.org/S58807641","display_name":"Clinical Physiology","issn_l":"0144-5979","issn":["0144-5979","1365-2281"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Physiology","raw_type":"journal-article"},{"id":"pmid:9413644","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9413644","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical physiology (Oxford, England)","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2391359225","https://openalex.org/W2072404808","https://openalex.org/W2810837601","https://openalex.org/W2076746883","https://openalex.org/W1468408920","https://openalex.org/W3123276812","https://openalex.org/W2000536299","https://openalex.org/W3175366528","https://openalex.org/W2223077590","https://openalex.org/W2566203065"],"abstract_inverted_index":{"We":[0],"examined":[1],"whether,":[2],"in":[3,36,67,102,108,123,189,197,200,206],"a":[4,13,33,109,160,167],"group":[5,41],"of":[6,18,42,54,61,69,111,172],"healthy":[7,38,44,190],"50":[8,52],"year-old":[9],"subjects,":[10],"there":[11,31,165],"was":[12,32,99,126,147],"relation":[14,168],"between":[15,169],"the":[16,19,62,140,152,170,173],"stiffness":[17,70,82,106,124,153,171,194],"common":[20,63],"carotid":[21,64,174],"artery":[22],"and":[23,48,114,139,176,186,209],"risk":[24,177,213],"factors":[25,178],"for":[26,179],"atherosclerosis":[27,180],"and,":[28],"further,":[29],"if":[30],"sex":[34],"difference":[35,122],"these":[37],"individuals.":[39],"A":[40],"248":[43],"subjects":[45],"(123":[46],"men":[47,113,198],"125":[49],"women),":[50],"all":[51],"years":[53],"age,":[55],"were":[56,72],"examined.":[57],"The":[58,96,193],"elastic":[59],"properties":[60],"artery,":[65],"measured":[66,134],"terms":[68],"index,":[71],"investigated":[73],"with":[74,116,151],"an":[75],"ultrasound":[76],"technique.":[77],"Men":[78],"had":[79],"significantly":[80,100,149],"higher":[81,196],"index":[83,107,125],"than":[84,199],"women":[85,115],"(5.46":[86],"+/-":[87,91],"1.32":[88],"vs.":[89],"5.04":[90],"1.05,":[92],"P":[93],"<":[94],"0.01).":[95],"arterial":[97,118,207],"diameter":[98],"larger":[101],"men.":[103],"When":[104],"comparing":[105],"subgroup":[110],"38":[112],"similar":[117],"diameters,":[119],"no":[120],"significant":[121,161],"found.":[127],"Multivariate":[128],"analysis":[129],"showed":[130],"that":[131],"smoking":[132],"habits,":[133],"as":[135,159,182],"pack-years,":[136],"insulin":[137,184],"levels":[138,185],"low-density":[141],"lipoprotein":[142,144],"(LDL)-/high-density":[143],"(HDL)-cholesterol":[145],"ratio":[146,188],"independently":[148],"associated":[150],"index.":[154],"Sex":[155],"did":[156],"not":[157],"emerge":[158],"variable.":[162],"In":[163],"conclusion,":[164],"is":[166,195],"arteries":[175],"such":[181],"smoking,":[183],"LDL-/HDL-cholesterol":[187],"50-year-old":[191],"subjects.":[192],"women,":[201],"probably":[202],"dependent":[203],"on":[204,212],"differences":[205],"size":[208],"possibly":[210],"also":[211],"factors.":[214]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}