{"id":"https://openalex.org/W2153249592","doi":"https://doi.org/10.1007/s11892-013-0453-1","title":"Advanced Glycation End Products (AGE) and Diabetes: Cause, Effect, or Both?","display_name":"Advanced Glycation End Products (AGE) and Diabetes: Cause, Effect, or Both?","publication_year":2013,"publication_date":"2013-11-28","ids":{"openalex":"https://openalex.org/W2153249592","doi":"https://doi.org/10.1007/s11892-013-0453-1","mag":"2153249592","pmid":"https://pubmed.ncbi.nlm.nih.gov/24292971","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3903318"},"language":"en","primary_location":{"id":"doi:10.1007/s11892-013-0453-1","doi":"https://doi.org/10.1007/s11892-013-0453-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11892-013-0453-1","pdf_url":null,"source":{"id":"https://openalex.org/S92651206","display_name":"Current Diabetes Reports","issn_l":"1534-4827","issn":["1534-4827","1539-0829"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Diabetes Reports","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3903318","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021790851","display_name":"Helen Vlassara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen Vlassara","raw_affiliation_strings":["Department of Geriatrics, Mount Sinai School of Medicine, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geriatrics, Mount Sinai School of Medicine, New York, NY, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007689491","display_name":"Jaime Uribarri","orcid":"https://orcid.org/0000-0001-9826-1134","observed_orcids":["https://orcid.org/0000-0001-9826-1134"]},"institutions":[{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jaime Uribarri","raw_affiliation_strings":["Department of Medicine, Mount Sinai School of Medicine, One Gustave Levy Place, Box 114, New York, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Mount Sinai School of Medicine, One Gustave Levy Place, Box 114, New York, NY, USA","institution_ids":["https://openalex.org/I98704320"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5007689491"],"corresponding_institution_ids":["https://openalex.org/I98704320"],"apc_list":{"value":4890,"currency":"USD","value_usd":4890},"apc_paid":null,"fwci":2.3355,"has_fulltext":false,"cited_by_count":620,"citation_normalized_percentile":{"value":0.93150685,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"14","issue":"1","first_page":"453","last_page":"453"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11745","display_name":"Potato Plant Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-glycation-end-products","display_name":"advanced glycation end products","score":1.0},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9670000076293945},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":1.0},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.871999979019165},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9120000004768372},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.6430000066757202},{"id":"https://openalex.org/keywords/beta-cell-injury","display_name":"beta-cell injury","score":0.8199999928474426},{"id":"https://openalex.org/keywords/western-diet","display_name":"Western diet","score":0.6710000038146973},{"id":"https://openalex.org/keywords/diabetes-complications","display_name":"diabetes complications","score":0.6100000143051147}],"concepts":[{"id":"https://openalex.org/C147990577","wikidata":"https://www.wikidata.org/wiki/Q25790","display_name":"Glycation","level":3,"score":0.9099069833755493},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8843174576759338},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7889984846115112},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.7406434416770935},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5961254835128784},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5919916033744812},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5340752601623535},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.4861135482788086},{"id":"https://openalex.org/C2776997535","wikidata":"https://www.wikidata.org/wiki/Q2556837","display_name":"Advanced glycation end-product","level":4,"score":0.4541463553905487},{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.44538936018943787},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.42307087779045105},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.4202738106250763},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35452038049697876},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3365371823310852},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3141235113143921},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.053412437438964844}],"mesh":[{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016640","descriptor_name":"Diabetes, Gestational","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017127","descriptor_name":"Glycation End Products, Advanced","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s11892-013-0453-1","doi":"https://doi.org/10.1007/s11892-013-0453-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11892-013-0453-1","pdf_url":null,"source":{"id":"https://openalex.org/S92651206","display_name":"Current Diabetes Reports","issn_l":"1534-4827","issn":["1534-4827","1539-0829"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Diabetes Reports","raw_type":"journal-article"},{"id":"pmid:24292971","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24292971","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current diabetes reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3903318","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3903318","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Diab Rep","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3903318","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3903318","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Curr Diab Rep","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2278767043","display_name":"Effects of Glycoxidative Stress on Human Aging","funder_award_id":"R37AG023188","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G4762460169","display_name":"General Clinical Research Center","funder_award_id":"M01RR000071","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G5652227433","display_name":"Effects of Glycoxidative Stress on Human Aging","funder_award_id":"R01DK091231","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8482084698","display_name":"AGING AND VASCULAR DISEASE: ROLE OF GLYCATION","funder_award_id":"R01AG009453","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337376","display_name":"NIH Clinical Center","ror":"https://ror.org/04vfsmv21"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W168848886","https://openalex.org/W326838645","https://openalex.org/W1520227077","https://openalex.org/W1565131882","https://openalex.org/W1664115270","https://openalex.org/W1970304246","https://openalex.org/W1971069803","https://openalex.org/W1971209988","https://openalex.org/W1975646168","https://openalex.org/W1980643281","https://openalex.org/W1985775184","https://openalex.org/W1986059252","https://openalex.org/W1989762800","https://openalex.org/W1990313130","https://openalex.org/W1991098479","https://openalex.org/W1995428435","https://openalex.org/W2003949605","https://openalex.org/W2010008476","https://openalex.org/W2010036181","https://openalex.org/W2012070284","https://openalex.org/W2025420631","https://openalex.org/W2026165785","https://openalex.org/W2027944101","https://openalex.org/W2029070304","https://openalex.org/W2030022427","https://openalex.org/W2036664753","https://openalex.org/W2037141143","https://openalex.org/W2044333192","https://openalex.org/W2044437167","https://openalex.org/W2050456578","https://openalex.org/W2060230815","https://openalex.org/W2061906058","https://openalex.org/W2072076332","https://openalex.org/W2081193499","https://openalex.org/W2084536221","https://openalex.org/W2088405534","https://openalex.org/W2089878313","https://openalex.org/W2092612186","https://openalex.org/W2095847921","https://openalex.org/W2099215884","https://openalex.org/W2109323721","https://openalex.org/W2109334664","https://openalex.org/W2112388240","https://openalex.org/W2113338980","https://openalex.org/W2113417828","https://openalex.org/W2122392577","https://openalex.org/W2124519441","https://openalex.org/W2124616258","https://openalex.org/W2124905655","https://openalex.org/W2130633974","https://openalex.org/W2139912326","https://openalex.org/W2142225048","https://openalex.org/W2142697880","https://openalex.org/W2143201143","https://openalex.org/W2149541479","https://openalex.org/W2150112427","https://openalex.org/W2152233222","https://openalex.org/W2153661281","https://openalex.org/W2154197060","https://openalex.org/W2156485867","https://openalex.org/W2158666727","https://openalex.org/W2158739365","https://openalex.org/W2159634370","https://openalex.org/W2164324917","https://openalex.org/W2164438863","https://openalex.org/W2173998026","https://openalex.org/W2188846692","https://openalex.org/W2188996532","https://openalex.org/W2200298303","https://openalex.org/W2335364913","https://openalex.org/W2409449647","https://openalex.org/W2411265807","https://openalex.org/W2473004715","https://openalex.org/W2769264260","https://openalex.org/W4322697143"],"related_works":["https://openalex.org/W2490273862","https://openalex.org/W2122392577","https://openalex.org/W2061906058","https://openalex.org/W2188996532","https://openalex.org/W2949032900","https://openalex.org/W2096255617","https://openalex.org/W4376131631","https://openalex.org/W2010036181","https://openalex.org/W4245286020","https://openalex.org/W3162598627"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":37},{"year":2025,"cited_by_count":47},{"year":2024,"cited_by_count":54},{"year":2023,"cited_by_count":75},{"year":2022,"cited_by_count":68},{"year":2021,"cited_by_count":66},{"year":2020,"cited_by_count":69},{"year":2019,"cited_by_count":48},{"year":2018,"cited_by_count":58},{"year":2017,"cited_by_count":30},{"year":2016,"cited_by_count":30},{"year":2015,"cited_by_count":26},{"year":2014,"cited_by_count":12}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}