{"id":"https://openalex.org/W2153160404","doi":"https://doi.org/10.1016/j.copbio.2013.01.008","title":"Human milk and related oligosaccharides as prebiotics","display_name":"Human milk and related oligosaccharides as prebiotics","publication_year":2013,"publication_date":"2013-02-19","ids":{"openalex":"https://openalex.org/W2153160404","doi":"https://doi.org/10.1016/j.copbio.2013.01.008","mag":"2153160404","pmid":"https://pubmed.ncbi.nlm.nih.gov/23434179"},"language":"en","primary_location":{"id":"doi:10.1016/j.copbio.2013.01.008","doi":"https://doi.org/10.1016/j.copbio.2013.01.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.copbio.2013.01.008","pdf_url":null,"source":{"id":"https://openalex.org/S23939942","display_name":"Current Opinion in Biotechnology","issn_l":"0958-1669","issn":["0958-1669","1879-0429"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Biotechnology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018409212","display_name":"Daniela Barile","orcid":"https://orcid.org/0000-0002-3889-1596","observed_orcids":["https://orcid.org/0000-0002-3889-1596"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniela Barile","raw_affiliation_strings":["Department of Food Science and Technology and Foods for Health Institute, University of California, Davis, CA 95616, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food Science and Technology and Foods for Health Institute, University of California, Davis, CA 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044428286","display_name":"Robert Adrian Rastall","orcid":"https://orcid.org/0000-0003-1775-5226","observed_orcids":["https://orcid.org/0000-0003-1775-5226"]},"institutions":[{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Robert A Rastall","raw_affiliation_strings":["Department of Food and Nutritional Sciences, University of Reading, PO Box 226, Whiteknights, Reading RG6 6AP, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Food and Nutritional Sciences, University of Reading, PO Box 226, Whiteknights, Reading RG6 6AP, UK","institution_ids":["https://openalex.org/I71052956"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5044428286"],"corresponding_institution_ids":["https://openalex.org/I71052956"],"apc_list":{"value":4530,"currency":"USD","value_usd":4530},"apc_paid":null,"fwci":2.1186,"has_fulltext":false,"cited_by_count":202,"citation_normalized_percentile":{"value":0.91563981,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"24","issue":"2","first_page":"214","last_page":"219"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12489","display_name":"Microbial Metabolites in Food Biotechnology","score":0.019500000402331352,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11561","display_name":"Protein Hydrolysis and Bioactive Peptides","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/human-milk-oligosaccharides","display_name":"human milk oligosaccharides","score":1.0},{"id":"https://openalex.org/keywords/prebiotics","display_name":"prebiotics","score":0.9929999709129333},{"id":"https://openalex.org/keywords/galactooligosaccharides","display_name":"galactooligosaccharides","score":0.9739999771118164},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7919999957084656},{"id":"https://openalex.org/keywords/infant-formula","display_name":"infant formula","score":0.9309999942779541},{"id":"https://openalex.org/keywords/intestinal-infection","display_name":"intestinal infection","score":0.44999998807907104},{"id":"https://openalex.org/keywords/functional-food-ingredients","display_name":"functional food ingredients","score":0.5569999814033508}],"concepts":[{"id":"https://openalex.org/C2779150110","wikidata":"https://www.wikidata.org/wiki/Q2287198","display_name":"Infant formula","level":2,"score":0.6977125406265259},{"id":"https://openalex.org/C2778724459","wikidata":"https://www.wikidata.org/wiki/Q127900","display_name":"Lactose","level":2,"score":0.659056544303894},{"id":"https://openalex.org/C2777726330","wikidata":"https://www.wikidata.org/wiki/Q320607","display_name":"Oligosaccharide","level":2,"score":0.6197452545166016},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5784967541694641},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.547088623046875},{"id":"https://openalex.org/C2775980262","wikidata":"https://www.wikidata.org/wiki/Q218870","display_name":"Prebiotic","level":2,"score":0.5264607071876526},{"id":"https://openalex.org/C2775871700","wikidata":"https://www.wikidata.org/wiki/Q22728","display_name":"Breast milk","level":2,"score":0.5236368179321289},{"id":"https://openalex.org/C2987857752","wikidata":"https://www.wikidata.org/wiki/Q12147","display_name":"Human health","level":2,"score":0.5121988654136658},{"id":"https://openalex.org/C3018122547","wikidata":"https://www.wikidata.org/wiki/Q5690813","display_name":"Health benefits","level":2,"score":0.4918558597564697},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.4597201347351074},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.4351482391357422},{"id":"https://openalex.org/C2909812603","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut microflora","level":3,"score":0.42222753167152405},{"id":"https://openalex.org/C2992940123","wikidata":"https://www.wikidata.org/wiki/Q8495","display_name":"Bovine milk","level":2,"score":0.4181329905986786},{"id":"https://openalex.org/C2780132029","wikidata":"https://www.wikidata.org/wiki/Q752276","display_name":"Functional food","level":2,"score":0.4118679165840149},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4004022181034088},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3698185980319977},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27330175042152405},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24398618936538696},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.12791365385055542},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.07991236448287964},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001644","descriptor_name":"Bifidobacterium","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001644","descriptor_name":"Bifidobacterium","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D005285","descriptor_name":"Fermentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005690","descriptor_name":"Galactose","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D005690","descriptor_name":"Galactose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005690","descriptor_name":"Galactose","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005690","descriptor_name":"Galactose","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007785","descriptor_name":"Lactose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008895","descriptor_name":"Milk, Human","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009844","descriptor_name":"Oligosaccharides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D041943","descriptor_name":"Infant Formula","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D041981","descriptor_name":"Gastrointestinal Tract","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D041981","descriptor_name":"Gastrointestinal Tract","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D054892","descriptor_name":"Metagenome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056692","descriptor_name":"Prebiotics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.copbio.2013.01.008","doi":"https://doi.org/10.1016/j.copbio.2013.01.008","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.copbio.2013.01.008","pdf_url":null,"source":{"id":"https://openalex.org/S23939942","display_name":"Current Opinion in Biotechnology","issn_l":"0958-1669","issn":["0958-1669","1879-0429"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Opinion in Biotechnology","raw_type":"journal-article"},{"id":"pmid:23434179","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23434179","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current opinion in biotechnology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8999999761581421},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.40450000762939453}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1502294326","https://openalex.org/W1919369226","https://openalex.org/W1943641126","https://openalex.org/W1976889499","https://openalex.org/W1979035951","https://openalex.org/W1981342236","https://openalex.org/W1981492630","https://openalex.org/W1983129426","https://openalex.org/W1985504995","https://openalex.org/W1998628730","https://openalex.org/W2000311971","https://openalex.org/W2005092419","https://openalex.org/W2008825357","https://openalex.org/W2017988783","https://openalex.org/W2020209665","https://openalex.org/W2023123334","https://openalex.org/W2034876046","https://openalex.org/W2043397698","https://openalex.org/W2044496774","https://openalex.org/W2053791316","https://openalex.org/W2054264327","https://openalex.org/W2054911521","https://openalex.org/W2067398413","https://openalex.org/W2081007801","https://openalex.org/W2084600096","https://openalex.org/W2093829386","https://openalex.org/W2110561681","https://openalex.org/W2113017639","https://openalex.org/W2125500166","https://openalex.org/W2129360213","https://openalex.org/W2130033198","https://openalex.org/W2131654335","https://openalex.org/W2132366863","https://openalex.org/W2138296428","https://openalex.org/W2140703378","https://openalex.org/W2151118402","https://openalex.org/W2151251013","https://openalex.org/W2153503726","https://openalex.org/W2154347931","https://openalex.org/W2162088497","https://openalex.org/W2162228100","https://openalex.org/W2166136944","https://openalex.org/W2749895126","https://openalex.org/W6743321566"],"related_works":["https://openalex.org/W1502252594","https://openalex.org/W2185249472","https://openalex.org/W2048118713","https://openalex.org/W2791508667","https://openalex.org/W2169254557","https://openalex.org/W3039404330","https://openalex.org/W4298087079","https://openalex.org/W2152510600","https://openalex.org/W2395136779","https://openalex.org/W1998331545"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":13},{"year":2024,"cited_by_count":14},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":19},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":18},{"year":2018,"cited_by_count":17},{"year":2017,"cited_by_count":19},{"year":2016,"cited_by_count":21},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}