{"id":"https://openalex.org/W2153147323","doi":"https://doi.org/10.1161/01.res.26.5.527","title":"Frequency Function of Transit Times through Dog Pulmonary Circulation","display_name":"Frequency Function of Transit Times through Dog Pulmonary Circulation","publication_year":1970,"publication_date":"1970-05-01","ids":{"openalex":"https://openalex.org/W2153147323","doi":"https://doi.org/10.1161/01.res.26.5.527","mag":"2153147323","pmid":"https://pubmed.ncbi.nlm.nih.gov/4910133"},"language":"en","primary_location":{"id":"doi:10.1161/01.res.26.5.527","doi":"https://doi.org/10.1161/01.res.26.5.527","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.res.26.5.527","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.26.5.527","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.26.5.527","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109033203","display_name":"Attilio Maseri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"ATTILIO MASERI","raw_affiliation_strings":["Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","ATTILIO MASERI Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"ATTILIO MASERI Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022245774","display_name":"Paolo Caldini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"PAOLO CALDINI","raw_affiliation_strings":["Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","PAOLO CALDINI Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"PAOLO CALDINI Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113602044","display_name":"Solbert Permutt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"SOLBERT PERMUTT","raw_affiliation_strings":["Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","SOLBERT PERMUTT Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"SOLBERT PERMUTT Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109011925","display_name":"Kenneth L. Zierler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108290504","display_name":"University of Pisa","ror":"https://ror.org/03ad39j10","country_code":"IT","type":"education","lineage":["https://openalex.org/I108290504"]},{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"KENNETH L. ZIERLER","raw_affiliation_strings":["Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","KENNETH L. ZIERLER Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"KENNETH L. ZIERLER Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205Clayton Laboratories for Study of Control of Cell Function in Health and Disease, Department of Medicine, and Departments of Physiology and of Environmental Medicine, The Johns Hopkins University, Baltimore, Maryland 21205","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Universita de Pisa, Clinica Medica Generale, Centro di Medicina Nucleare, Pisa, Italy","institution_ids":["https://openalex.org/I108290504"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":16.1209,"has_fulltext":true,"cited_by_count":65,"citation_normalized_percentile":{"value":0.99190419,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"26","issue":"5","first_page":"527","last_page":"543"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.5785999894142151,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.5785999894142151,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10728","display_name":"Pulmonary Hypertension Research and Treatments","score":0.21330000460147858,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.053599998354911804,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-circulation","display_name":"pulmonary circulation","score":0.8080000281333923},{"id":"https://openalex.org/keywords/pulmonary-transit-time","display_name":"pulmonary transit time","score":0.6290000081062317},{"id":"https://openalex.org/keywords/frequency-function","display_name":"frequency function","score":0.6899999976158142},{"id":"https://openalex.org/keywords/deconvolution","display_name":"deconvolution","score":0.8519999980926514},{"id":"https://openalex.org/keywords/recirculation","display_name":"recirculation","score":0.6589999794960022},{"id":"https://openalex.org/keywords/skewness","display_name":"skewness","score":0.8519999980926514},{"id":"https://openalex.org/keywords/coefficient-of-variation","display_name":"coefficient of variation","score":0.7080000042915344},{"id":"https://openalex.org/keywords/hypovolemia","display_name":"hypovolemia","score":0.902999997138977},{"id":"https://openalex.org/keywords/cardiac-output","display_name":"cardiac output","score":0.8240000009536743},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C2778863792","wikidata":"https://www.wikidata.org/wiki/Q16909918","display_name":"TRACER","level":2,"score":0.588333249092102},{"id":"https://openalex.org/C132459708","wikidata":"https://www.wikidata.org/wiki/Q744069","display_name":"Extrapolation","level":2,"score":0.5659192204475403},{"id":"https://openalex.org/C122342681","wikidata":"https://www.wikidata.org/wiki/Q330828","display_name":"Skewness","level":2,"score":0.5501075387001038},{"id":"https://openalex.org/C139940330","wikidata":"https://www.wikidata.org/wiki/Q596579","display_name":"Cardiac output","level":3,"score":0.5464913845062256},{"id":"https://openalex.org/C2780940725","wikidata":"https://www.wikidata.org/wiki/Q206280","display_name":"Pulmonary artery","level":2,"score":0.5193094611167908},{"id":"https://openalex.org/C3019368741","wikidata":"https://www.wikidata.org/wiki/Q653305","display_name":"Mean transit time","level":4,"score":0.48133739829063416},{"id":"https://openalex.org/C96618451","wikidata":"https://www.wikidata.org/wiki/Q3028008","display_name":"Dilution","level":2,"score":0.46884334087371826},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.43760403990745544},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.4199720025062561},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3815303146839142},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35405194759368896},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.33407264947891235},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3210299611091614},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.2805823087692261},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.24227777123451233},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.19016501307487488},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.1403300166130066},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.09326064586639404},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0711437463760376},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0},{"id":"https://openalex.org/C135691158","wikidata":"https://www.wikidata.org/wiki/Q7168308","display_name":"Perfusion scanning","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002302","descriptor_name":"Cardiac Output","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003626","descriptor_name":"Data Display","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006339","descriptor_name":"Heart Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007201","descriptor_name":"Indicator Dilution Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007208","descriptor_name":"Indocyanine Green","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008433","descriptor_name":"Mathematics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008722","descriptor_name":"Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011652","descriptor_name":"Pulmonary Circulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012709","descriptor_name":"Serum Albumin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013667","descriptor_name":"Technetium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1161/01.res.26.5.527","doi":"https://doi.org/10.1161/01.res.26.5.527","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.res.26.5.527","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.26.5.527","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},{"id":"pmid:4910133","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4910133","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation research","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.991.1056","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.991.1056","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://circres.ahajournals.org/content/circresaha/26/5/527.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1161/01.res.26.5.527","doi":"https://doi.org/10.1161/01.res.26.5.527","is_oa":true,"landing_page_url":"https://doi.org/10.1161/01.res.26.5.527","pdf_url":"https://www.ahajournals.org/doi/pdf/10.1161/01.RES.26.5.527","source":{"id":"https://openalex.org/S10652568","display_name":"Circulation Research","issn_l":"0009-7330","issn":["0009-7330","1524-4571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation Research","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2153147323.pdf","grobid_xml":"https://content.openalex.org/works/W2153147323.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W93300450","https://openalex.org/W1975035521","https://openalex.org/W2001291731","https://openalex.org/W2013724909","https://openalex.org/W2034239818","https://openalex.org/W2043116169","https://openalex.org/W2053353852","https://openalex.org/W2058622992","https://openalex.org/W2071697241","https://openalex.org/W2098641266","https://openalex.org/W2106811039","https://openalex.org/W2142163482","https://openalex.org/W2397642446","https://openalex.org/W2408444171","https://openalex.org/W2431554875"],"related_works":["https://openalex.org/W7097721659","https://openalex.org/W1982994633","https://openalex.org/W2241900008","https://openalex.org/W1751948893","https://openalex.org/W2044652855","https://openalex.org/W2336695376","https://openalex.org/W2072690680","https://openalex.org/W1912127726","https://openalex.org/W20202190","https://openalex.org/W2006721945"],"abstract_inverted_index":{"The":[0,69],"frequency":[1,70,199],"function":[2,71],"of":[3,17,20,48,72,105,111,126,154,163,173,191,201,211,232],"transit":[4,30,40,75,106,165,202,220],"times":[5,31,41,76,203,221],"through":[6],"the":[7,37,81,127,141,184,198,206],"pulmonary":[8,33,73,148],"vascular":[9,74],"system":[10],"in":[11,96,171],"dogs":[12],"was":[13,77,92,194],"obtained":[14,108,122],"by":[15,94,100,109,123,205,223],"deconvolution":[16,52,110],"a":[18,160],"pair":[19],"simultaneous":[21],"tracer":[22,26,113,129],"dilution":[23,27],"curves.":[24],"One":[25],"curve":[28,144],"represented":[29,39],"from":[32,42],"artery":[34],"to":[35,45,80,132,138,152,159,168,181,187,230],"aorta;":[36],"other":[38],"left":[43,88],"atrium":[44],"aorta.":[46],"Theory":[47],"and":[49,87,167,213,225],"requirements":[50],"for":[51],"are":[53],"presented.":[54],"Two":[55],"preparations":[56],"were":[57,118,215],"used:":[58],"closed":[59],"chest":[60,64],"with":[61,65,120,217],"recirculation,":[62,117],"open":[63],"only":[66],"myocardial":[67],"recirculation.":[68,134],"skewed":[78],"markedly":[79],"right.":[82],"At":[83],"constant":[84],"cardiac":[85,227],"output":[86,228],"atrial":[89],"pressure":[90],"it":[91],"unaffected":[93],"change":[95],"heart":[97],"rate":[98],"or":[99,189],"respiratory":[101],"movements.":[102],"Frequency":[103],"functions":[104,200],"time":[107,166],"observed":[112,142],"concentration":[114,130,143,185],"curves,":[115],"including":[116],"compared":[119],"those":[121],"monoexponential":[124,156],"extrapolation":[125,157],"same":[128],"curves":[131],"\"eliminate\"":[133],"If":[135,176],"recirculation":[136,177],"seemed":[137],"appear":[139],"before":[140],"(aortic":[145],"sampling":[146],"following":[147],"arterial":[149],"injection)":[150],"fell":[151,186],"20%":[153],"peak,":[155,192],"led":[158],"10%":[161,188],"overestimate":[162],"mean":[164,219],"greater":[169],"errors":[170],"estimate":[172],"higher":[174],"moments.":[175],"did":[178],"not":[179],"seem":[180],"occur":[182],"until":[183],"less":[190],"there":[193],"no":[195],"difference":[196],"between":[197],"calculated":[204],"two":[207],"methods.":[208],"Increased":[209],"coefficients":[210],"variance":[212],"skewness":[214],"associated":[216],"large":[218],"produced":[222],"hypovolemia":[224],"reduced":[226],"secondary":[229],"withdrawal":[231],"blood.":[233]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
