{"id":"https://openalex.org/W215312005","doi":null,"title":"Disturbed protein arginine methylation in hyperhomocysteinemia","display_name":"Disturbed protein arginine methylation in hyperhomocysteinemia","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W215312005","mag":"215312005"},"language":"en","primary_location":{"id":"mag:215312005","doi":null,"is_oa":false,"landing_page_url":"https://repositorio.ul.pt/bitstream/10451/9944/1/ulsd067099_td_Ruben_Esse.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018964480","display_name":"Ruben Esse","orcid":"https://orcid.org/0000-0002-8381-0628","observed_orcids":["https://orcid.org/0000-0002-8381-0628"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ruben Esse","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5018964480"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.7134000062942505,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.7134000062942505,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.2667999863624573,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13551","display_name":"Biochemical effects in animals","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-arginine-methylation","display_name":"arginine methylation","score":0.984000027179718},{"id":"https://openalex.org/keywords/hyperhomocysteinemia","display_name":"hyperhomocysteinemia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/homocysteine","display_name":"homocysteine","score":0.9200000166893005},{"id":"https://openalex.org/keywords/protein-methylation","display_name":"protein methylation","score":0.5299999713897705},{"id":"https://openalex.org/keywords/methionine-metabolism","display_name":"methionine metabolism","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C2776523773","wikidata":"https://www.wikidata.org/wiki/Q1093815","display_name":"Hyperhomocysteinemia","level":3,"score":0.8329062461853027},{"id":"https://openalex.org/C2777468819","wikidata":"https://www.wikidata.org/wiki/Q173670","display_name":"Arginine","level":3,"score":0.7420734167098999},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.6873527765274048},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.48153096437454224},{"id":"https://openalex.org/C2777090595","wikidata":"https://www.wikidata.org/wiki/Q192466","display_name":"Homocysteine","level":2,"score":0.4730776250362396},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.35799700021743774},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3349434733390808},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.331203818321228},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3135320544242859},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3071921765804291},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.1544504463672638},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06675711274147034},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.05118393898010254}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:215312005","doi":null,"is_oa":false,"landing_page_url":"https://repositorio.ul.pt/bitstream/10451/9944/1/ulsd067099_td_Ruben_Esse.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":280,"referenced_works":["https://openalex.org/W55959524","https://openalex.org/W1492953040","https://openalex.org/W1524465921","https://openalex.org/W1553462851","https://openalex.org/W1592832248","https://openalex.org/W1608099415","https://openalex.org/W1625966995","https://openalex.org/W1640411033","https://openalex.org/W1711482514","https://openalex.org/W1743509092","https://openalex.org/W1755052449","https://openalex.org/W1762583610","https://openalex.org/W1860367105","https://openalex.org/W1871384741","https://openalex.org/W1891008845","https://openalex.org/W1908510719","https://openalex.org/W1928122316","https://openalex.org/W1934395836","https://openalex.org/W1935061717","https://openalex.org/W1963559299","https://openalex.org/W1964083099","https://openalex.org/W1964195679","https://openalex.org/W1964366675","https://openalex.org/W1964394233","https://openalex.org/W1964423003","https://openalex.org/W1964792512","https://openalex.org/W1966131437","https://openalex.org/W1966861384","https://openalex.org/W1966952656","https://openalex.org/W1968702845","https://openalex.org/W1968717432","https://openalex.org/W1970584787","https://openalex.org/W1974077096","https://openalex.org/W1975025950","https://openalex.org/W1975584750","https://openalex.org/W1976479148","https://openalex.org/W1977032812","https://openalex.org/W1977146608","https://openalex.org/W1977873599","https://openalex.org/W1978094951","https://openalex.org/W1981143785","https://openalex.org/W1981188079","https://openalex.org/W1981926097","https://openalex.org/W1984829930","https://openalex.org/W1985569328","https://openalex.org/W1985946354","https://openalex.org/W1988420439","https://openalex.org/W1988530181","https://openalex.org/W1989572989","https://openalex.org/W1989800882","https://openalex.org/W1991857561","https://openalex.org/W1991903960","https://openalex.org/W1993023587","https://openalex.org/W1994248940","https://openalex.org/W1995873131","https://openalex.org/W1995931698","https://openalex.org/W1996233154","https://openalex.org/W1997663843","https://openalex.org/W1998033959","https://openalex.org/W1998913715","https://openalex.org/W2001335285","https://openalex.org/W2001338200","https://openalex.org/W2001673235","https://openalex.org/W2001856542","https://openalex.org/W2002699856","https://openalex.org/W2004078197","https://openalex.org/W2004336032","https://openalex.org/W2004417257","https://openalex.org/W2004433500","https://openalex.org/W2005016697","https://openalex.org/W2005880805","https://openalex.org/W2006664693","https://openalex.org/W2007104599","https://openalex.org/W2007818910","https://openalex.org/W2008201148","https://openalex.org/W2010177605","https://openalex.org/W2011550644","https://openalex.org/W2012113208","https://openalex.org/W2012400169","https://openalex.org/W2013207372","https://openalex.org/W2014448038","https://openalex.org/W2014913485","https://openalex.org/W2016093991","https://openalex.org/W2018096113","https://openalex.org/W2018508622","https://openalex.org/W2021836023","https://openalex.org/W2022200846","https://openalex.org/W2022365165","https://openalex.org/W2023077617","https://openalex.org/W2023952336","https://openalex.org/W2023992909","https://openalex.org/W2024353529","https://openalex.org/W2024805521","https://openalex.org/W2024869670","https://openalex.org/W2025347753","https://openalex.org/W2028761226","https://openalex.org/W2028980645","https://openalex.org/W2029033935","https://openalex.org/W2032271983","https://openalex.org/W2033228105","https://openalex.org/W2034530729","https://openalex.org/W2035129369","https://openalex.org/W2035536565","https://openalex.org/W2036846090","https://openalex.org/W2037078495","https://openalex.org/W2039461477","https://openalex.org/W2040402810","https://openalex.org/W2040654271","https://openalex.org/W2040733421","https://openalex.org/W2042883526","https://openalex.org/W2044549899","https://openalex.org/W2044682380","https://openalex.org/W2046648607","https://openalex.org/W2046814977","https://openalex.org/W2046934643","https://openalex.org/W2047712302","https://openalex.org/W2048134537","https://openalex.org/W2048564333","https://openalex.org/W2049603650","https://openalex.org/W2049848026","https://openalex.org/W2050002679","https://openalex.org/W2050157038","https://openalex.org/W2050703495","https://openalex.org/W2050812658","https://openalex.org/W2052588755","https://openalex.org/W2053178949","https://openalex.org/W2053431309","https://openalex.org/W2053961392","https://openalex.org/W2054476774","https://openalex.org/W2054847530","https://openalex.org/W2055598140","https://openalex.org/W2056525001","https://openalex.org/W2057129148","https://openalex.org/W2057259507","https://openalex.org/W2057624222","https://openalex.org/W2061523668","https://openalex.org/W2063382200","https://openalex.org/W2066006328","https://openalex.org/W2066688265","https://openalex.org/W2067410739","https://openalex.org/W2068111179","https://openalex.org/W2070057671","https://openalex.org/W2071695216","https://openalex.org/W2072531665","https://openalex.org/W2072908498","https://openalex.org/W2073454252","https://openalex.org/W2073608241","https://openalex.org/W2073646360","https://openalex.org/W2074085971","https://openalex.org/W2074344807","https://openalex.org/W2076057425","https://openalex.org/W2076142854","https://openalex.org/W2077342495","https://openalex.org/W2078410199","https://openalex.org/W2078573253","https://openalex.org/W2078798575","https://openalex.org/W2080252893","https://openalex.org/W2080265235","https://openalex.org/W2081204899","https://openalex.org/W2081532048","https://openalex.org/W2082262146","https://openalex.org/W2083381537","https://openalex.org/W2083963235","https://openalex.org/W2084424974","https://openalex.org/W2084669626","https://openalex.org/W2085443300","https://openalex.org/W2088121802","https://openalex.org/W2089065260","https://openalex.org/W2089176660","https://openalex.org/W2089580499","https://openalex.org/W2090552017","https://openalex.org/W2090667021","https://openalex.org/W2091533776","https://openalex.org/W2092618826","https://openalex.org/W2092809155","https://openalex.org/W2093572184","https://openalex.org/W2093694324","https://openalex.org/W2094069132","https://openalex.org/W2094239981","https://openalex.org/W2094778744","https://openalex.org/W2096104522","https://openalex.org/W2097664820","https://openalex.org/W2098487456","https://openalex.org/W2098717784","https://openalex.org/W2098848421","https://openalex.org/W2099007490","https://openalex.org/W2099067892","https://openalex.org/W2102294256","https://openalex.org/W2103502218","https://openalex.org/W2103535459","https://openalex.org/W2103554498","https://openalex.org/W2103851892","https://openalex.org/W2104047605","https://openalex.org/W2105276853","https://openalex.org/W2107057466","https://openalex.org/W2107811013","https://openalex.org/W2109544293","https://openalex.org/W2111899435","https://openalex.org/W2112881016","https://openalex.org/W2112903461","https://openalex.org/W2113198638","https://openalex.org/W2115135910","https://openalex.org/W2117582003","https://openalex.org/W2117586137","https://openalex.org/W2117892897","https://openalex.org/W2118015493","https://openalex.org/W2119141156","https://openalex.org/W2119998073","https://openalex.org/W2120124457","https://openalex.org/W2120749153","https://openalex.org/W2122070162","https://openalex.org/W2122563784","https://openalex.org/W2125896627","https://openalex.org/W2127398467","https://openalex.org/W2129372343","https://openalex.org/W2129598432","https://openalex.org/W2129871288","https://openalex.org/W2129959153","https://openalex.org/W2131318608","https://openalex.org/W2133377749","https://openalex.org/W2134087142","https://openalex.org/W2135152296","https://openalex.org/W2136057401","https://openalex.org/W2136113495","https://openalex.org/W2136618799","https://openalex.org/W2137891310","https://openalex.org/W2137959371","https://openalex.org/W2139488526","https://openalex.org/W2139610636","https://openalex.org/W2140418591","https://openalex.org/W2140483277","https://openalex.org/W2142075603","https://openalex.org/W2142258451","https://openalex.org/W2142800783","https://openalex.org/W2142811977","https://openalex.org/W2142983041","https://openalex.org/W2143568149","https://openalex.org/W2143855758","https://openalex.org/W2144198424","https://openalex.org/W2144238576","https://openalex.org/W2144279208","https://openalex.org/W2144514501","https://openalex.org/W2145693405","https://openalex.org/W2146519286","https://openalex.org/W2147024245","https://openalex.org/W2147176162","https://openalex.org/W2147464835","https://openalex.org/W2149996399","https://openalex.org/W2151120155","https://openalex.org/W2151960388","https://openalex.org/W2153110646","https://openalex.org/W2153111398","https://openalex.org/W2153715212","https://openalex.org/W2154334994","https://openalex.org/W2155031941","https://openalex.org/W2155352554","https://openalex.org/W2155408998","https://openalex.org/W2155651511","https://openalex.org/W2156211472","https://openalex.org/W2156797167","https://openalex.org/W2157036139","https://openalex.org/W2157503991","https://openalex.org/W2158976466","https://openalex.org/W2159058075","https://openalex.org/W2160712387","https://openalex.org/W2161391196","https://openalex.org/W2161887334","https://openalex.org/W2162449964","https://openalex.org/W2163821350","https://openalex.org/W2166389246","https://openalex.org/W2166612636","https://openalex.org/W2166691146","https://openalex.org/W2167388258","https://openalex.org/W2168665618","https://openalex.org/W2169549058","https://openalex.org/W2257551340","https://openalex.org/W2336005275","https://openalex.org/W2340646666","https://openalex.org/W2412554695","https://openalex.org/W2612812586"],"related_works":["https://openalex.org/W7018634344","https://openalex.org/W6990122947","https://openalex.org/W1964083099","https://openalex.org/W2906616417","https://openalex.org/W7096085173","https://openalex.org/W2883529217","https://openalex.org/W1620829529","https://openalex.org/W4313416718","https://openalex.org/W2081939674","https://openalex.org/W3175728533"],"abstract_inverted_index":{"Tese":[0],"de":[1,6,9],"doutoramento,":[2],"Farmacia":[3],"(Bioquimica),":[4],"Universidade":[5],"Lisboa,":[7],"Faculdade":[8],"Farmacia,":[10],"2013":[11]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}