{"id":"https://openalex.org/W2151839057","doi":"https://doi.org/10.1124/jpet.114.213793","title":"Brexpiprazole I: In Vitro and In Vivo Characterization of a Novel Serotonin-Dopamine Activity Modulator","display_name":"Brexpiprazole I: In Vitro and In Vivo Characterization of a Novel Serotonin-Dopamine Activity Modulator","publication_year":2014,"publication_date":"2014-06-20","ids":{"openalex":"https://openalex.org/W2151839057","doi":"https://doi.org/10.1124/jpet.114.213793","mag":"2151839057","pmid":"https://pubmed.ncbi.nlm.nih.gov/24947465"},"language":"en","primary_location":{"id":"doi:10.1124/jpet.114.213793","doi":"https://doi.org/10.1124/jpet.114.213793","is_oa":false,"landing_page_url":"https://doi.org/10.1124/jpet.114.213793","pdf_url":null,"source":{"id":"https://openalex.org/S102125482","display_name":"Journal of Pharmacology and Experimental Therapeutics","issn_l":"0022-3565","issn":["0022-3565","1521-0103"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pharmacology and Experimental Therapeutics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055989025","display_name":"Kenji Maeda","orcid":"https://orcid.org/0000-0002-9424-1491","observed_orcids":["https://orcid.org/0000-0002-9424-1491"]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Kenji Maeda","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.) Maeda.Kenji@otsuka.jp","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.) Maeda.Kenji@otsuka.jp","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029990947","display_name":"Haruhiko Sugino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Haruhiko Sugino","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hitomi Akazawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Hitomi Akazawa","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052500240","display_name":"Naoki Amada","orcid":"https://orcid.org/0000-0002-9625-6240","observed_orcids":["https://orcid.org/0000-0002-9625-6240"]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Naoki Amada","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jun Shimada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Jun Shimada","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087792958","display_name":"Takashi Futamura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Takashi Futamura","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050010393","display_name":"Hiroshi Yamashita","orcid":"https://orcid.org/0000-0001-7731-2473","observed_orcids":["https://orcid.org/0000-0001-7731-2473"]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Hiroshi Yamashita","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nobuaki Ito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Nobuaki Ito","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108358185","display_name":"Robert D. McQuade","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Robert D. McQuade","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111608303","display_name":"Arne M\u00f8rk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Arne M\u00f8rk","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007209385","display_name":"Alan Lars Pehrson","orcid":"https://orcid.org/0000-0002-0470-0202","observed_orcids":["https://orcid.org/0000-0002-0470-0202"]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Alan L. Pehrson","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035463393","display_name":"Morten Hentzer","orcid":"https://orcid.org/0000-0002-4574-3743","observed_orcids":["https://orcid.org/0000-0002-4574-3743"]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Morten Hentzer","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111545630","display_name":"Vibeke Nielsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Vibeke Nielsen","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074909311","display_name":"Christoffer Bundgaard","orcid":"https://orcid.org/0009-0009-5222-4499","observed_orcids":["https://orcid.org/0009-0009-5222-4499"]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Christoffer Bundgaard","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111649623","display_name":"J\u00f8rn Arnt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"J\u00f8rn Arnt","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110191635","display_name":"Tine B. Stensb\u00f8l","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Tine Bryan Stensb\u00f8l","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062112121","display_name":"Tetsuro Kikuchi","orcid":"https://orcid.org/0000-0002-3902-7302","observed_orcids":["https://orcid.org/0000-0002-3902-7302"]},"institutions":[{"id":"https://openalex.org/I114030911","display_name":"Otsuka (Japan)","ror":"https://ror.org/013k5y296","country_code":"JP","type":"company","lineage":["https://openalex.org/I114030911"]},{"id":"https://openalex.org/I133593841","display_name":"Lundbeck (Denmark)","ror":"https://ror.org/0564cd633","country_code":"DK","type":"company","lineage":["https://openalex.org/I133593841"]},{"id":"https://openalex.org/I4210086062","display_name":"Otsuka (United States)","ror":"https://ror.org/00ew4na22","country_code":"US","type":"company","lineage":["https://openalex.org/I114030911","https://openalex.org/I4210086062"]},{"id":"https://openalex.org/I4210150391","display_name":"Lundbeck (United States)","ror":"https://ror.org/04a2yjk98","country_code":"US","type":"company","lineage":["https://openalex.org/I133593841","https://openalex.org/I4210150391"]},{"id":"https://openalex.org/I4405268153","display_name":"Otsuka Pharmaceutical Development & Commercialization, Inc. (United States)","ror":"https://ror.org/001nxvg84","country_code":"US","type":"company","lineage":["https://openalex.org/I4405268153"]}],"countries":["DK","JP","US"],"is_corresponding":false,"raw_author_name":"Tetsuro Kikuchi","raw_affiliation_strings":["Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.); Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.); Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.); and Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Lundbeck Research USA, Paramus, New Jersey (A.L.P.)","institution_ids":["https://openalex.org/I4210150391"]},{"raw_affiliation_string":"Neuroscience Drug Discovery, H. Lundbeck A/S, Valby, Denmark (A.M., M.H., V.N., C.B., J.A., T.B.S.)","institution_ids":["https://openalex.org/I133593841"]},{"raw_affiliation_string":"Otsuka Pharmaceutical Development & Commercialization, Princeton, New Jersey (R.D.M.)","institution_ids":["https://openalex.org/I4210086062","https://openalex.org/I4405268153"]},{"raw_affiliation_string":"Qs' Research Institute, Otsuka Pharmaceutical Co., Ltd. Tokushima, Japan (K.M., H.S., H.A., N.A., J.S., T.F., H.Y., N.I., T.K.)","institution_ids":["https://openalex.org/I114030911"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":10.9061,"has_fulltext":false,"cited_by_count":368,"citation_normalized_percentile":{"value":0.99286672,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"350","issue":"3","first_page":"589","last_page":"604"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.14139999449253082,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.02160000056028366,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brexpiprazole","display_name":"brexpiprazole","score":0.8080000281333923},{"id":"https://openalex.org/keywords/5-ht1a-receptor","display_name":"5-HT1A receptor","score":0.8109999895095825},{"id":"https://openalex.org/keywords/5-ht2a-receptor","display_name":"5-HT2A receptor","score":0.9399999976158142},{"id":"https://openalex.org/keywords/dopamine-d2-receptor","display_name":"dopamine D2 receptor","score":0.7580000162124634},{"id":"https://openalex.org/keywords/adrenergic-receptors","display_name":"adrenergic receptors","score":0.7519999742507935},{"id":"https://openalex.org/keywords/partial-agonism","display_name":"partial agonism","score":0.7039999961853027},{"id":"https://openalex.org/keywords/receptor-binding-affinity","display_name":"receptor binding affinity","score":0.8500000238418579},{"id":"https://openalex.org/keywords/nucleus-accumbens-dopamine","display_name":"nucleus accumbens dopamine","score":0.7940000295639038},{"id":"https://openalex.org/keywords/homovanillic-acid","display_name":"homovanillic acid","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C58732023","wikidata":"https://www.wikidata.org/wiki/Q770260","display_name":"Partial agonist","level":4,"score":0.701290488243103},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6930279731750488},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6522336006164551},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.6482176184654236},{"id":"https://openalex.org/C44208683","wikidata":"https://www.wikidata.org/wiki/Q15335165","display_name":"Dopamine receptor D2","level":3,"score":0.6035028696060181},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5930641293525696},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.5379252433776855},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5301913619041443},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.5095527172088623},{"id":"https://openalex.org/C53910766","wikidata":"https://www.wikidata.org/wiki/Q238516","display_name":"5-HT receptor","level":4,"score":0.4950524866580963},{"id":"https://openalex.org/C2779867896","wikidata":"https://www.wikidata.org/wiki/Q2357007","display_name":"Fenoldopam","level":4,"score":0.41933420300483704},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29017171263694763},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.255916953086853},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17738217115402222},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003412","descriptor_name":"Cricetulus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003412","descriptor_name":"Cricetulus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003412","descriptor_name":"Cricetulus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003412","descriptor_name":"Cricetulus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006224","descriptor_name":"Cricetinae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012701","descriptor_name":"Serotonin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013876","descriptor_name":"Thiophenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015259","descriptor_name":"Dopamine Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015363","descriptor_name":"Quinolones","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016466","descriptor_name":"CHO Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016466","descriptor_name":"CHO Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016466","descriptor_name":"CHO Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016466","descriptor_name":"CHO Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017208","descriptor_name":"Rats, Wistar","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D017448","descriptor_name":"Receptors, Dopamine D2","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D018490","descriptor_name":"Serotonin Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D044282","descriptor_name":"Receptor, Serotonin, 5-HT1A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044282","descriptor_name":"Receptor, Serotonin, 5-HT1A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044282","descriptor_name":"Receptor, Serotonin, 5-HT1A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D044282","descriptor_name":"Receptor, Serotonin, 5-HT1A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065127","descriptor_name":"Dopamine D2 Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065127","descriptor_name":"Dopamine D2 Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065127","descriptor_name":"Dopamine D2 Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065127","descriptor_name":"Dopamine D2 Receptor Antagonists","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1124/jpet.114.213793","doi":"https://doi.org/10.1124/jpet.114.213793","is_oa":false,"landing_page_url":"https://doi.org/10.1124/jpet.114.213793","pdf_url":null,"source":{"id":"https://openalex.org/S102125482","display_name":"Journal of Pharmacology and Experimental Therapeutics","issn_l":"0022-3565","issn":["0022-3565","1521-0103"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pharmacology and Experimental Therapeutics","raw_type":"journal-article"},{"id":"pmid:24947465","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24947465","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of pharmacology and experimental therapeutics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.7400000095367432,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320324177","display_name":"Otsuka Pharmaceutical","ror":"https://ror.org/013k5y296"},{"id":"https://openalex.org/F4320327918","display_name":"H. Lundbeck A/S","ror":"https://ror.org/0564cd633"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W95266284","https://openalex.org/W147747432","https://openalex.org/W948132221","https://openalex.org/W1502718364","https://openalex.org/W1639136703","https://openalex.org/W1895729847","https://openalex.org/W1934926274","https://openalex.org/W1971179661","https://openalex.org/W1976682355","https://openalex.org/W1977708259","https://openalex.org/W1979700184","https://openalex.org/W1980544360","https://openalex.org/W1982487023","https://openalex.org/W1983575851","https://openalex.org/W1985913814","https://openalex.org/W1986314685","https://openalex.org/W1990488797","https://openalex.org/W1992501050","https://openalex.org/W1999389706","https://openalex.org/W2009234753","https://openalex.org/W2013849876","https://openalex.org/W2018295858","https://openalex.org/W2021890797","https://openalex.org/W2025034831","https://openalex.org/W2028730857","https://openalex.org/W2029267570","https://openalex.org/W2034629571","https://openalex.org/W2035188344","https://openalex.org/W2037861196","https://openalex.org/W2043075431","https://openalex.org/W2046280658","https://openalex.org/W2048736385","https://openalex.org/W2049407111","https://openalex.org/W2050834933","https://openalex.org/W2054722815","https://openalex.org/W2066640528","https://openalex.org/W2070357412","https://openalex.org/W2074631079","https://openalex.org/W2077760177","https://openalex.org/W2080964010","https://openalex.org/W2083252023","https://openalex.org/W2105891047","https://openalex.org/W2108373295","https://openalex.org/W2114801996","https://openalex.org/W2121361221","https://openalex.org/W2122995608","https://openalex.org/W2124201657","https://openalex.org/W2127339766","https://openalex.org/W2128014576","https://openalex.org/W2132862169","https://openalex.org/W2137172145","https://openalex.org/W2137679105","https://openalex.org/W2149734448","https://openalex.org/W2154299176","https://openalex.org/W2163010981","https://openalex.org/W2163815564","https://openalex.org/W2166770851","https://openalex.org/W2184174642","https://openalex.org/W2326718013","https://openalex.org/W2400755806","https://openalex.org/W2460731912","https://openalex.org/W2469225747","https://openalex.org/W4232352194","https://openalex.org/W6603854659","https://openalex.org/W6630070299","https://openalex.org/W6636814241","https://openalex.org/W6718470610"],"related_works":["https://openalex.org/W2058091174","https://openalex.org/W3099606857","https://openalex.org/W2017637061","https://openalex.org/W1828383458","https://openalex.org/W4312232053","https://openalex.org/W4206347286","https://openalex.org/W2156790153","https://openalex.org/W2419529664","https://openalex.org/W2290954425","https://openalex.org/W4290155861"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":28},{"year":2025,"cited_by_count":36},{"year":2024,"cited_by_count":35},{"year":2023,"cited_by_count":29},{"year":2022,"cited_by_count":26},{"year":2021,"cited_by_count":39},{"year":2020,"cited_by_count":34},{"year":2019,"cited_by_count":33},{"year":2018,"cited_by_count":27},{"year":2017,"cited_by_count":19},{"year":2016,"cited_by_count":35},{"year":2015,"cited_by_count":24},{"year":2014,"cited_by_count":3}],"updated_date":"2026-10-09T09:14:12.587421","created_date":"2025-10-10T00:00:00"}