{"id":"https://openalex.org/W2151409255","doi":"https://doi.org/10.1006/excr.1997.3484","title":"Uncoupling of Cell Cycle Arrest from the Expression of Monocytic Differentiation Markers in HL60 Cell Variants","display_name":"Uncoupling of Cell Cycle Arrest from the Expression of Monocytic Differentiation Markers in HL60 Cell Variants","publication_year":1997,"publication_date":"1997-05-01","ids":{"openalex":"https://openalex.org/W2151409255","doi":"https://doi.org/10.1006/excr.1997.3484","mag":"2151409255","pmid":"https://pubmed.ncbi.nlm.nih.gov/9168815"},"language":"en","primary_location":{"id":"doi:10.1006/excr.1997.3484","doi":"https://doi.org/10.1006/excr.1997.3484","is_oa":false,"landing_page_url":"https://doi.org/10.1006/excr.1997.3484","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086633044","display_name":"George P. Studzinski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"George P. Studzinski","raw_affiliation_strings":["Department of Pathology, UMD-New Jersey Medical School, Newark 07103, USA","Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, UMD-New Jersey Medical School, Newark 07103, USA","institution_ids":["https://openalex.org/I4402554120"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061632816","display_name":"Bina Rathod","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bina Rathod","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075558767","display_name":"Qing Mei Wang","orcid":"https://orcid.org/0000-0003-4655-4917","observed_orcids":["https://orcid.org/0000-0003-4655-4917"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qing Mei Wang","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060004715","display_name":"Jie Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jie Rao","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103","institution_ids":["https://openalex.org/I4402554120"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100403374","display_name":"Fan Zhang","orcid":"https://orcid.org/0000-0001-5890-8212","observed_orcids":["https://orcid.org/0000-0001-5890-8212"]},"institutions":[{"id":"https://openalex.org/I4402554120","display_name":"Rutgers New Jersey Medical School","ror":"https://ror.org/014ye1258","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4390039302","https://openalex.org/I4402554120"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fan Zhang","raw_affiliation_strings":["Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, UMD\u2014New Jersey Medical School, 185 South Orange Avenue, Newark, New Jersey, 07103","institution_ids":["https://openalex.org/I4402554120"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5086633044"],"corresponding_institution_ids":["https://openalex.org/I4402554120"],"apc_list":{"value":3270,"currency":"USD","value_usd":3270},"apc_paid":null,"fwci":2.1847,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.87911659,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"232","issue":"2","first_page":"376","last_page":"387"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.8256999850273132,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.8256999850273132,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.14949999749660492,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hl-60-cells","display_name":"HL-60 cells","score":0.9710000157356262},{"id":"https://openalex.org/keywords/1-25-dihydroxyvitamin-d3","display_name":"1,25-dihydroxyvitamin D3","score":0.9350000023841858},{"id":"https://openalex.org/keywords/vitamin-d-receptor","display_name":"vitamin D receptor","score":0.6259999871253967},{"id":"https://openalex.org/keywords/retinoid-x-receptor","display_name":"retinoid X receptor","score":0.8339999914169312},{"id":"https://openalex.org/keywords/monocyte-differentiation","display_name":"monocyte differentiation","score":0.906000018119812},{"id":"https://openalex.org/keywords/cell-cycle-arrest","display_name":"cell cycle arrest","score":0.8870000243186951},{"id":"https://openalex.org/keywords/g1-cell-cycle-arrest","display_name":"G1 cell cycle arrest","score":0.7480000257492065},{"id":"https://openalex.org/keywords/non-specific-esterase","display_name":"nonspecific esterase","score":0.9819999933242798},{"id":"https://openalex.org/keywords/hypotetraploidy","display_name":"hypotetraploidy","score":0.8289999961853027},{"id":"https://openalex.org/keywords/dna-content","display_name":"DNA content","score":0.5630000233650208},{"id":"https://openalex.org/keywords/sp1","display_name":"Sp1","score":0.9660000205039978},{"id":"https://openalex.org/keywords/leukemia-cell-differentiation","display_name":"leukemia cell differentiation","score":0.5849999785423279}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8809671401977539},{"id":"https://openalex.org/C2778903051","wikidata":"https://www.wikidata.org/wiki/Q5630035","display_name":"HL60","level":3,"score":0.7445707321166992},{"id":"https://openalex.org/C148738053","wikidata":"https://www.wikidata.org/wiki/Q210861","display_name":"Cellular differentiation","level":3,"score":0.6203384399414062},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.5883316397666931},{"id":"https://openalex.org/C2778513237","wikidata":"https://www.wikidata.org/wiki/Q419553","display_name":"CD14","level":3,"score":0.5489929914474487},{"id":"https://openalex.org/C2781184567","wikidata":"https://www.wikidata.org/wiki/Q107244","display_name":"Monocyte","level":2,"score":0.4754074215888977},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4537707269191742},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3662131428718567},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3638876974582672},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.31492066383361816},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2902950644493103},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.2377694547176361},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15208041667938232},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13580846786499023}],"mesh":[{"descriptor_ui":"D002117","descriptor_name":"Calcitriol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009000","descriptor_name":"Monocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D010751","descriptor_name":"Phosphopyruvate Hydratase","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D015214","descriptor_name":"Antigens, Differentiation, Myelomonocytic","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016329","descriptor_name":"Sp1 Transcription Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018167","descriptor_name":"Receptors, Calcitriol","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018168","descriptor_name":"Receptors, Retinoic Acid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D018922","descriptor_name":"HL-60 Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D018922","descriptor_name":"HL-60 Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018950","descriptor_name":"Lipopolysaccharide Receptors","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D047488","descriptor_name":"Retinoid X Receptors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1006/excr.1997.3484","doi":"https://doi.org/10.1006/excr.1997.3484","is_oa":false,"landing_page_url":"https://doi.org/10.1006/excr.1997.3484","pdf_url":null,"source":{"id":"https://openalex.org/S132505712","display_name":"Experimental Cell Research","issn_l":"0014-4827","issn":["0014-4827","1090-2422"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Cell Research","raw_type":"journal-article"},{"id":"pmid:9168815","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9168815","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental cell research","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1638846173","display_name":"Vitamin D Analogs as Adjuvants in Chemotherapy of Cancer","funder_award_id":"R01CA044722","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W92934419","https://openalex.org/W147454428","https://openalex.org/W151965067","https://openalex.org/W1493755175","https://openalex.org/W1504600626","https://openalex.org/W1508371220","https://openalex.org/W1554600230","https://openalex.org/W1601173552","https://openalex.org/W1616778816","https://openalex.org/W1968028322","https://openalex.org/W1987040411","https://openalex.org/W1993489940","https://openalex.org/W1995127270","https://openalex.org/W2000157312","https://openalex.org/W2012571603","https://openalex.org/W2029157767","https://openalex.org/W2037196809","https://openalex.org/W2039671291","https://openalex.org/W2047668353","https://openalex.org/W2052561467","https://openalex.org/W2062124441","https://openalex.org/W2068195632","https://openalex.org/W2069368198","https://openalex.org/W2074696981","https://openalex.org/W2083436346","https://openalex.org/W2087934471","https://openalex.org/W2088981623","https://openalex.org/W2089126365","https://openalex.org/W2097155745","https://openalex.org/W2111686546","https://openalex.org/W2115532408","https://openalex.org/W2117263637","https://openalex.org/W2127067451","https://openalex.org/W2141083396","https://openalex.org/W2150784028","https://openalex.org/W2169337684","https://openalex.org/W2327237185","https://openalex.org/W2329211716","https://openalex.org/W2416417238"],"related_works":["https://openalex.org/W1975167498","https://openalex.org/W2346293618","https://openalex.org/W1525067662","https://openalex.org/W2115532408","https://openalex.org/W2039671291","https://openalex.org/W2091347687","https://openalex.org/W1995074996","https://openalex.org/W2044013798","https://openalex.org/W2022177704","https://openalex.org/W2018108516"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}
