{"id":"https://openalex.org/W2150032631","doi":"https://doi.org/10.1093/jnci/djq343","title":"CSPG4 Protein as a New Target for the Antibody-Based Immunotherapy of Triple-Negative Breast Cancer","display_name":"CSPG4 Protein as a New Target for the Antibody-Based Immunotherapy of Triple-Negative Breast Cancer","publication_year":2010,"publication_date":"2010-09-18","ids":{"openalex":"https://openalex.org/W2150032631","doi":"https://doi.org/10.1093/jnci/djq343","mag":"2150032631","pmid":"https://pubmed.ncbi.nlm.nih.gov/20852124","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2950168"},"language":"en","primary_location":{"id":"doi:10.1093/jnci/djq343","doi":"https://doi.org/10.1093/jnci/djq343","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/djq343","pdf_url":"https://academic.oup.com/jnci/article-pdf/102/19/1496/17310649/djq343.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jnci/article-pdf/102/19/1496/17310649/djq343.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100370823","display_name":"Xinhui Wang","orcid":"https://orcid.org/0000-0001-5579-1311","observed_orcids":["https://orcid.org/0000-0001-5579-1311"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinhui Wang","raw_affiliation_strings":["University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077597600","display_name":"Takuya Osada","orcid":"https://orcid.org/0000-0003-1424-5001","observed_orcids":["https://orcid.org/0000-0003-1424-5001"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Takuya Osada","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100345124","display_name":"Yangyang Wang","orcid":"https://orcid.org/0000-0002-2095-5002","observed_orcids":["https://orcid.org/0000-0002-2095-5002","https://orcid.org/0009-0008-2786-5350","https://orcid.org/0009-0006-2457-2582","https://orcid.org/0009-0007-5259-5818","https://orcid.org/0000-0001-5810-8928"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yangyang Wang","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100681418","display_name":"Ling Yu","orcid":"https://orcid.org/0000-0002-8781-3033","observed_orcids":["https://orcid.org/0000-0002-8781-3033"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ling Yu","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010669068","display_name":"Koichi Sakakura","orcid":"https://orcid.org/0000-0003-0218-9903","observed_orcids":["https://orcid.org/0000-0003-0218-9903"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Koichi Sakakura","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Akihiro Katayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Akihiro Katayama","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078768906","display_name":"James B. McCarthy","orcid":"https://orcid.org/0000-0002-7233-0047","observed_orcids":["https://orcid.org/0000-0002-7233-0047"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James B. McCarthy","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044108002","display_name":"Adam Brufsky","orcid":"https://orcid.org/0000-0001-8080-7960","observed_orcids":["https://orcid.org/0000-0001-8080-7960","https://orcid.org/0009-0006-2725-3579"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adam Brufsky","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088131318","display_name":"Mamatha Chivukula","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mamatha Chivukula","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064936288","display_name":"Thaer Khoury","orcid":"https://orcid.org/0000-0002-8112-6590","observed_orcids":["https://orcid.org/0000-0002-8112-6590"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thaer Khoury","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023821870","display_name":"David S. Hsu","orcid":"https://orcid.org/0000-0002-8149-7180","observed_orcids":["https://orcid.org/0000-0002-8149-7180"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David S. Hsu","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112035683","display_name":"William Thomas Barry","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William T. Barry","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012804507","display_name":"Herbert Kim Lyerly","orcid":"https://orcid.org/0000-0002-0063-4770","observed_orcids":["https://orcid.org/0000-0002-0063-4770"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Kim Lyerly","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104348991","display_name":"Timothy M. Clay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy M. Clay","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028669896","display_name":"Soldano Ferrone","orcid":"https://orcid.org/0000-0003-2900-8834","observed_orcids":["https://orcid.org/0000-0003-2900-8834"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]},{"id":"https://openalex.org/I130238516","display_name":"University of Minnesota","ror":"https://ror.org/017zqws13","country_code":"US","type":"education","lineage":["https://openalex.org/I130238516"]},{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]},{"id":"https://openalex.org/I4390039358","display_name":"Masonic Cancer Center","ror":"https://ror.org/05x083d20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Soldano Ferrone","raw_affiliation_strings":["Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF); Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA; Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC; Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM); Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I170201317","https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Affiliations of authors: University of Pittsburgh Cancer Institute, Pittsburgh, PA (XW, YW, LY, KS, AK, SF)","institution_ids":["https://openalex.org/I4210128526"]},{"raw_affiliation_string":"Department of Immunology (XW, LY, SF), Department of Surgery (YW, KS, AK, SF), Department of Medicine (AB), and Department of Pathology (MC, SF), School of Medicine, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathology and Masonic Cancer Center, University of Minnesota, Minneapolis, MN (JBM)","institution_ids":["https://openalex.org/I130238516","https://openalex.org/I4390039358"]},{"raw_affiliation_string":"Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY (TK)","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Surgery (TO, HKL, TMC), Department of Medicine (DSH), Department of Biostatistics and Bioinformatics (WTB), Department of Immunology (HKL, TMC), and Department of Pathology (HKL), Duke University Comprehensive Cancer Center, Duke University Medical Center, Durham, NC","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5436,"currency":"USD","value_usd":5436},"apc_paid":null,"fwci":2.5203,"has_fulltext":true,"cited_by_count":191,"citation_normalized_percentile":{"value":0.89320252,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"102","issue":"19","first_page":"1496","last_page":"1512"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.007400000002235174,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cspg4","display_name":"CSPG4","score":0.9459999799728394},{"id":"https://openalex.org/keywords/triple-negative-breast-cancer","display_name":"triple-negative breast cancer","score":0.9959999918937683},{"id":"https://openalex.org/keywords/antibody-based-immunotherapy","display_name":"antibody-based immunotherapy","score":0.9480000138282776},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.6779999732971191},{"id":"https://openalex.org/keywords/lung-metastasis","display_name":"lung metastasis","score":0.9100000262260437},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.8080000281333923},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.6840000152587891},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9860000014305115},{"id":"https://openalex.org/keywords/tumor-growth-inhibition","display_name":"tumor growth inhibition","score":0.722000002861023},{"id":"https://openalex.org/keywords/metastasis-regression","display_name":"metastasis regression","score":0.3720000088214874},{"id":"https://openalex.org/keywords/metastasis-directed-therapy","display_name":"metastasis-directed therapy","score":0.41999998688697815},{"id":"https://openalex.org/keywords/pleural-effusion","display_name":"pleural effusion","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C2780110267","wikidata":"https://www.wikidata.org/wiki/Q7843332","display_name":"Triple-negative breast cancer","level":4,"score":0.8891646862030029},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6110175251960754},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5696097612380981},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5424090623855591},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.5273309946060181},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5206074714660645},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5056018829345703},{"id":"https://openalex.org/C2780674031","wikidata":"https://www.wikidata.org/wiki/Q2012719","display_name":"Cancer immunotherapy","level":4,"score":0.4740329086780548},{"id":"https://openalex.org/C2775895372","wikidata":"https://www.wikidata.org/wiki/Q5104536","display_name":"Chondroitin sulfate proteoglycan","level":4,"score":0.4627630114555359},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4380110502243042},{"id":"https://openalex.org/C2779335624","wikidata":"https://www.wikidata.org/wiki/Q407976","display_name":"Proteoglycan","level":3,"score":0.34767401218414307},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2951936423778534},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18062126636505127},{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000099216","descriptor_name":"Chondroitin Sulfate Proteoglycan 4","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008545","descriptor_name":"Melanoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D008545","descriptor_name":"Melanoma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D010996","descriptor_name":"Pleural Effusion","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011508","descriptor_name":"Chondroitin Sulfate Proteoglycans","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D011508","descriptor_name":"Chondroitin Sulfate Proteoglycans","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014183","descriptor_name":"Transplantation, Heterologous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015986","descriptor_name":"Confounding Factors, Epidemiologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D020133","descriptor_name":"Reverse Transcriptase Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/jnci/djq343","doi":"https://doi.org/10.1093/jnci/djq343","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/djq343","pdf_url":"https://academic.oup.com/jnci/article-pdf/102/19/1496/17310649/djq343.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2191569","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2950168","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:20852124","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20852124","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the National Cancer Institute","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2950168","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2950168/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Natl Cancer Inst","raw_type":"Text"},{"id":"pmh:oai:open-archive.highwire.org:jnci:djq343v1","doi":null,"is_oa":false,"landing_page_url":"http://jnci.oxfordjournals.org/cgi/content/short/djq343v1","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/jnci/djq343","doi":"https://doi.org/10.1093/jnci/djq343","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jnci/djq343","pdf_url":"https://academic.oup.com/jnci/article-pdf/102/19/1496/17310649/djq343.pdf","source":{"id":"https://openalex.org/S98010888","display_name":"JNCI Journal of the National Cancer Institute","issn_l":"0027-8874","issn":["0027-8874","1460-2105"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JNCI: Journal of the National Cancer Institute","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1626516806","display_name":"Combinatorial targeting of melanoma initiating cells","funder_award_id":"R01CA138188","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G1727281504","display_name":"HLA classl complex expression in breast cancer immunity","funder_award_id":"R01CA113861","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G385462102","display_name":"Rational Design of HMW-MAA Peptide Mimics","funder_award_id":"R01CA105500","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6628359320","display_name":"SPORE IN BREAST CANCER","funder_award_id":"P50CA068438","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6883209116","display_name":"Redirecting Specificity of Viral Specific T Cells","funder_award_id":"R01CA095447","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8451443032","display_name":"Melanoma Cell Surface Proteoglycans in Metastasis","funder_award_id":"R01CA082295","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8627795258","display_name":"Invastigations on High Molecular Weight-Melanoma Associated Antigen as a target of the immunotherapy","funder_award_id":"21592185","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320306470","display_name":"Elsa U. Pardee Foundation","ror":"https://ror.org/05sjnvv07"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2150032631.pdf","grobid_xml":"https://content.openalex.org/works/W2150032631.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W1485771066","https://openalex.org/W1510526370","https://openalex.org/W1520425169","https://openalex.org/W1535887975","https://openalex.org/W1584205859","https://openalex.org/W1730078381","https://openalex.org/W1920719136","https://openalex.org/W1950483962","https://openalex.org/W1969997692","https://openalex.org/W1973041517","https://openalex.org/W1980757374","https://openalex.org/W1981464883","https://openalex.org/W1982684297","https://openalex.org/W1989076816","https://openalex.org/W1992324708","https://openalex.org/W1995646379","https://openalex.org/W1997688669","https://openalex.org/W1997801409","https://openalex.org/W1998967221","https://openalex.org/W1999463736","https://openalex.org/W2009642161","https://openalex.org/W2010098991","https://openalex.org/W2020697195","https://openalex.org/W2023427658","https://openalex.org/W2023817734","https://openalex.org/W2025134405","https://openalex.org/W2025621596","https://openalex.org/W2033768992","https://openalex.org/W2035880310","https://openalex.org/W2038569449","https://openalex.org/W2048109276","https://openalex.org/W2050593870","https://openalex.org/W2052249193","https://openalex.org/W2056433388","https://openalex.org/W2059929752","https://openalex.org/W2065077716","https://openalex.org/W2067713351","https://openalex.org/W2068430237","https://openalex.org/W2073245859","https://openalex.org/W2073385822","https://openalex.org/W2073935157","https://openalex.org/W2076092809","https://openalex.org/W2076110142","https://openalex.org/W2076491580","https://openalex.org/W2076583198","https://openalex.org/W2076636899","https://openalex.org/W2086133143","https://openalex.org/W2087067449","https://openalex.org/W2089145565","https://openalex.org/W2097255042","https://openalex.org/W2102085111","https://openalex.org/W2102596641","https://openalex.org/W2106210309","https://openalex.org/W2110238167","https://openalex.org/W2115031942","https://openalex.org/W2128347157","https://openalex.org/W2128424539","https://openalex.org/W2128985829","https://openalex.org/W2129567747","https://openalex.org/W2130037917","https://openalex.org/W2136178883","https://openalex.org/W2137070860","https://openalex.org/W2138474420","https://openalex.org/W2141083396","https://openalex.org/W2141413204","https://openalex.org/W2142739240","https://openalex.org/W2143383125","https://openalex.org/W2149860500","https://openalex.org/W2149882425","https://openalex.org/W2155360968","https://openalex.org/W2155390148","https://openalex.org/W2155507705","https://openalex.org/W2155824282","https://openalex.org/W2157840751","https://openalex.org/W2264655007","https://openalex.org/W4302341942","https://openalex.org/W6634838219","https://openalex.org/W6649890844"],"related_works":["https://openalex.org/W2789600872","https://openalex.org/W2056344131","https://openalex.org/W4239116546","https://openalex.org/W2329758702","https://openalex.org/W2141413204","https://openalex.org/W1977263681","https://openalex.org/W4213456016","https://openalex.org/W2783055842","https://openalex.org/W4410791606","https://openalex.org/W2095338751"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,24,84,102,139,279,327],"cell":[2,64,154,184,311,347],"surface":[3],"proteoglycan,":[4],"chondroitin":[5],"sulfate":[6],"proteoglycan":[7],"4":[8],"(CSPG4),":[9],"is":[10,40],"a":[11,223,322],"potential":[12],"target":[13,324],"for":[14,19,29,142,282,325,345],"monoclonal":[15],"antibody":[16],"(mAb)-based":[17],"immunotherapy":[18],"many":[20],"types":[21],"of":[22,26,86,95,104,110,146,174,209,219,236,245,306,330,341],"cancer.":[23],"lack":[25],"effective":[27],"therapy":[28],"triple-negative":[30],"breast":[31,81,134,196],"cancer":[32,82,135,197],"(TNBC)":[33],"prompted":[34],"us":[35],"to":[36,107,118,255],"examine":[37],"whether":[38],"CSPG4":[39,52,167,320],"expressed":[41,171],"in":[42,57,62,72,75,100,133,137,152,157,172,182,187,190,212,222,273,292,299,310],"TNBC":[43,60,63,96,179,183,210,224,346],"and":[44,69,71,93,117,122,156,186,207,270,288,303,314,350],"can":[45],"be":[46],"targeted":[47],"with":[48],"CSPG4-specific":[49,87,199,331],"mAb.":[50],"METHODS:":[51],"protein":[53,168],"expression":[54],"was":[55,98,131,169,333],"assessed":[56],"44":[58,176],"primary":[59,178],"lesions,":[61],"lines":[65,155],"HS578T,":[66],"MDA-MB-231,":[67],"MDA-MB-435,":[68],"SUM149,":[70],"tumor":[73,111,123,188,220,271,293,301],"cells":[74,97,189,211],"pleural":[76,191],"effusions":[77,192],"from":[78,193],"12":[79,127,194],"metastatic":[80,195,237],"patients.":[83,198],"effect":[85,145,284],"mAb":[88,105,147,200,214,262,332],"225.28":[89,106,148,201,215,231,263],"on":[90],"growth,":[91,205],"adhesion,":[92,206],"migration":[94,208],"tested":[99,132],"vitro.":[101,213],"ability":[103],"induce":[108],"regression":[109,218],"metastases":[112,269],"(n":[113,125],"=":[114,126,239,247,253],"7":[115],"mice)":[116],"inhibit":[119],"spontaneous":[120,267],"metastasis":[121,221,228],"recurrence":[124],"mice":[128],"per":[129],"group)":[130],"models":[136],"mice.":[138],"mechanisms":[140,280],"responsible":[141,281],"the":[143,153,158,175,300,339],"antitumor":[144,283,328],"were":[149,164],"also":[150],"investigated":[151],"mouse":[159,277],"models.":[160],"All":[161],"statistical":[162],"tests":[163],"two-sided.":[165],"RESULTS:":[166],"preferentially":[170],"32":[173],"(72.7%)":[177],"lesions":[180],"tested,":[181],"lines,":[185],"statistically":[202,264],"significantly":[203,265],"inhibited":[204],"induced":[216],"73.1%":[217],"cell-derived":[225],"experimental":[226],"lung":[227,268],"model":[229],"(mAb":[230],"vs":[232,241],"control,":[233],"mean":[234,246],"area":[235],"nodules":[238],"44590.8":[240],"165950.8":[242],"\u03bcm(2);":[243,257],"difference":[244],"121360.0":[248],"\u03bcm(2),":[249],"95%":[250],"confidence":[251],"interval":[252],"91010.7":[254],"151709.4":[256],"P":[258],"<":[259],".001).":[260],"Additionally,":[261],"reduced":[266,289,304],"recurrences":[272],"an":[274],"orthotopic":[275],"xenograft":[276],"model.":[278],"included":[285],"increased":[286],"apoptosis":[287],"mitotic":[290],"activity":[291,329],"cells,":[294],"decreased":[295],"blood":[296],"vessel":[297],"density":[298],"microenvironment,":[302],"activation":[305],"signaling":[307,342],"pathways":[308,343],"involved":[309],"survival,":[312,348],"proliferation":[313],"metastasis.":[315,351],"CONCLUSIONS:":[316],"This":[317],"study":[318],"identified":[319],"as":[321],"new":[323],"TNBC.":[326],"mediated":[334],"by":[335],"multiple":[336],"mechanisms,":[337],"including":[338],"inhibition":[340],"crucial":[344],"proliferation,":[349]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":28},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":12},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":15},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}