{"id":"https://openalex.org/W2149940432","doi":"https://doi.org/10.1021/ic020591p","title":"Inhibition of Transcription in Vitro by Anticancer Active Dirhodium(II) Complexes","display_name":"Inhibition of Transcription in Vitro by Anticancer Active Dirhodium(II) Complexes","publication_year":2003,"publication_date":"2003-01-24","ids":{"openalex":"https://openalex.org/W2149940432","doi":"https://doi.org/10.1021/ic020591p","mag":"2149940432","pmid":"https://pubmed.ncbi.nlm.nih.gov/12588165"},"language":"en","primary_location":{"id":"doi:10.1021/ic020591p","doi":"https://doi.org/10.1021/ic020591p","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ic020591p","pdf_url":null,"source":{"id":"https://openalex.org/S171072222","display_name":"Inorganic Chemistry","issn_l":"0020-1669","issn":["0020-1669","1520-510X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inorganic Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042457398","display_name":"Karn R. Sorasaenee","orcid":"https://orcid.org/0000-0002-3364-1918","observed_orcids":["https://orcid.org/0000-0002-3364-1918"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karn Sorasaenee","raw_affiliation_strings":["Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210","institution_ids":["https://openalex.org/I52357470","https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113214650","display_name":"Patty K.\u2010L. Fu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patty K.-L. Fu","raw_affiliation_strings":["Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210","institution_ids":["https://openalex.org/I52357470","https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000146662","display_name":"Alfredo Milton Angeles-Boza","orcid":"https://orcid.org/0000-0002-5560-4405","observed_orcids":["https://orcid.org/0000-0002-5560-4405"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alfredo M. Angeles-Boza","raw_affiliation_strings":["Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210","institution_ids":["https://openalex.org/I52357470","https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056201103","display_name":"Kim R. Dunbar","orcid":"https://orcid.org/0000-0001-5728-7805","observed_orcids":["https://orcid.org/0000-0001-5728-7805"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kim R. Dunbar","raw_affiliation_strings":["Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210","institution_ids":["https://openalex.org/I52357470","https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038676358","display_name":"Claudia Turr\u00f3","orcid":"https://orcid.org/0000-0003-3202-5870","observed_orcids":["https://orcid.org/0000-0003-3202-5870"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]},{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Claudia Turro","raw_affiliation_strings":["Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Texas A&M University, College Station, Texas 77843, and Department of Chemistry, The Ohio State University, Columbus, Ohio 43210","institution_ids":["https://openalex.org/I52357470","https://openalex.org/I91045830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5038676358","https://openalex.org/A5056201103"],"corresponding_institution_ids":["https://openalex.org/I52357470","https://openalex.org/I91045830"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.6759,"has_fulltext":false,"cited_by_count":70,"citation_normalized_percentile":{"value":0.90054097,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"42","issue":"4","first_page":"1267","last_page":"1271"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10092","display_name":"Organometallic Complex Synthesis and Catalysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11746","display_name":"Inorganic and Organometallic Chemistry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dirhodium-ii-complexes","display_name":"dirhodium(II) complexes","score":0.9879999756813049},{"id":"https://openalex.org/keywords/transcription-inhibition","display_name":"transcription inhibition","score":0.7789999842643738},{"id":"https://openalex.org/keywords/dna-binding","display_name":"DNA binding","score":0.8180000185966492},{"id":"https://openalex.org/keywords/calf-thymus-dna","display_name":"calf thymus DNA","score":0.8830000162124634},{"id":"https://openalex.org/keywords/t7-rna-polymerase","display_name":"T7 RNA polymerase","score":0.7990000247955322},{"id":"https://openalex.org/keywords/cisplatin","display_name":"cisplatin","score":0.6679999828338623},{"id":"https://openalex.org/keywords/anticancer-metal-complexes","display_name":"anticancer metal complexes","score":0.6650000214576721},{"id":"https://openalex.org/keywords/phen-ligand","display_name":"phen ligand","score":0.5590000152587891},{"id":"https://openalex.org/keywords/binding-constant","display_name":"binding constant","score":0.46799999475479126},{"id":"https://openalex.org/keywords/anticancer-mechanism","display_name":"anticancer mechanism","score":0.4480000138282776},{"id":"https://openalex.org/keywords/protein-dna-interactions","display_name":"protein-DNA interactions","score":0.3970000147819519},{"id":"https://openalex.org/keywords/ruthenium-ii-complexes","display_name":"ruthenium(II) complexes","score":0.531000018119812},{"id":"https://openalex.org/keywords/enzyme-inhibition-mechanism","display_name":"enzyme inhibition mechanism","score":0.4269999861717224},{"id":"https://openalex.org/keywords/platinum-based-anticancer-drugs","display_name":"platinum anticancer drugs","score":0.3720000088214874}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9862380623817444},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.7634586095809937},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.5034331679344177},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.42823249101638794},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.406454473733902},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2808484435081482},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002945","descriptor_name":"Cisplatin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004354","descriptor_name":"Drug Screening Assays, Antitumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004587","descriptor_name":"Electrophoresis, Agar Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012238","descriptor_name":"Rhodium","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012321","descriptor_name":"DNA-Directed RNA Polymerases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013237","descriptor_name":"Stereoisomerism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D014764","descriptor_name":"Viral Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015394","descriptor_name":"Molecular Structure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020128","descriptor_name":"Inhibitory Concentration 50","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/ic020591p","doi":"https://doi.org/10.1021/ic020591p","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ic020591p","pdf_url":null,"source":{"id":"https://openalex.org/S171072222","display_name":"Inorganic Chemistry","issn_l":"0020-1669","issn":["0020-1669","1520-510X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inorganic Chemistry","raw_type":"journal-article"},{"id":"pmid:12588165","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12588165","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Inorganic chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1528887896","https://openalex.org/W1542268894","https://openalex.org/W1543662618","https://openalex.org/W1567392545","https://openalex.org/W1575417251","https://openalex.org/W1826381055","https://openalex.org/W1964722273","https://openalex.org/W1965699649","https://openalex.org/W1966152037","https://openalex.org/W1969040089","https://openalex.org/W1971920947","https://openalex.org/W1972115380","https://openalex.org/W1975253000","https://openalex.org/W1980095889","https://openalex.org/W1981863209","https://openalex.org/W1983846414","https://openalex.org/W1985403032","https://openalex.org/W1987119636","https://openalex.org/W1989163046","https://openalex.org/W1991655119","https://openalex.org/W1996888865","https://openalex.org/W2000858083","https://openalex.org/W2009230970","https://openalex.org/W2014839221","https://openalex.org/W2018433407","https://openalex.org/W2027568735","https://openalex.org/W2031106427","https://openalex.org/W2032959348","https://openalex.org/W2035473280","https://openalex.org/W2035699003","https://openalex.org/W2038822441","https://openalex.org/W2043610941","https://openalex.org/W2044738848","https://openalex.org/W2062924200","https://openalex.org/W2064885067","https://openalex.org/W2068568063","https://openalex.org/W2069967580","https://openalex.org/W2080431827","https://openalex.org/W2085737617","https://openalex.org/W2087196035","https://openalex.org/W2089019299","https://openalex.org/W2089570339","https://openalex.org/W2095372566","https://openalex.org/W2100872145","https://openalex.org/W2117445439","https://openalex.org/W2164836262","https://openalex.org/W2312493202","https://openalex.org/W2952583614","https://openalex.org/W2953283015","https://openalex.org/W3138157653"],"related_works":["https://openalex.org/W1997598566","https://openalex.org/W2082036959","https://openalex.org/W1969509030","https://openalex.org/W2034412778","https://openalex.org/W2052173156","https://openalex.org/W2076870971","https://openalex.org/W2157164007","https://openalex.org/W2012756940","https://openalex.org/W6940458499","https://openalex.org/W2027242415"],"abstract_inverted_index":{"The":[0,18,49,76],"DNA":[1,27,64,125,165],"binding":[2,19,69],"and":[3,12,39,46,82,95,133,192],"inhibition":[4,186],"of":[5,21,54,58,63,70,80,87,120,130,150,163,183,206],"transcription":[6,89,138,175],"in":[7,173],"vitro":[8],"by":[9],"neutral":[10],"Rh(2)(mu-O(2)CCH(3))(4)":[11,45,81,191],"cationic":[13],"cis-[Rh(2)(mu-O(2)CCH(3))(2)(phen)(2)](2+)":[14,83,193],"complexes":[15,24,60,72,169],"were":[16,28,153],"investigated.":[17],"constants":[20],"the":[22,55,59,71,88,123,128,131,137,151,164,167,181,184,199],"two":[23],"to":[25,33,51,73,127,155,179,195],"calf-thymus":[26],"estimated":[29],"from":[30],"absorption":[31,57],"titrations":[32],"be":[34],"4.6":[35],"x":[36,41],"10(2)":[37],"M(-)(1)":[38,43],"1.7":[40],"10(4)":[42],"for":[44,106,136,140],"cis-[Rh(2)(mu-O(2)CCH(3))(2)(phen)(2)](2+),":[47],"respectively.":[48,97],"shift":[50],"higher":[52],"energies":[53],"low-energy":[56],"upon":[61],"addition":[62,129],"is":[65,90],"consistent":[66],"with":[67,110,122,166,198],"axial":[68],"duplex":[74],"DNA.":[75],"relative":[77],"concentrations,":[78],"[complex]/[DNA],":[79],"at":[84,143],"which":[85],"50%":[86,157],"inhibited":[91],"(R(inh)(50)),":[92],"are":[93,100],"0.0031":[94],"0.0011,":[96],"These":[98],"concentrations":[99,149],"significantly":[101,147],"lower":[102,148],"than":[103],"that":[104],"required":[105,154],"activated":[107],"cisplatin,":[108],"cis-[Pt(NH(3))(2)(H(2)O)(2)](2+),":[109,190],"R(inh)(50)":[111],"=":[112],"0.0085":[113],"under":[114],"similar":[115,161],"experimental":[116],"conditions.":[117],"Upon":[118],"incubation":[119,162],"cis-[Pt(NH(3))(2)(H(2)O)(2)](2+)":[121],"template":[124],"prior":[126],"enzyme":[132,200],"nucleobases":[134],"necessary":[135],"reaction":[139],"30":[141],"min":[142],"37":[144],"degrees":[145],"C,":[146],"complex":[152],"attain":[156],"inhibition.":[158,176,207],"In":[159],"contrast,":[160],"dirhodium":[168],"did":[170],"not":[171],"result":[172],"better":[174],"Experiments":[177],"designed":[178],"elucidate":[180],"mechanism":[182],"observed":[185],"indicate":[187],"that,":[188],"unlike":[189],"appear":[194],"interact":[196],"directly":[197],"T7-RNA":[201],"polymerase":[202],"as":[203],"their":[204],"mode":[205]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}