{"id":"https://openalex.org/W2149884102","doi":"https://doi.org/10.2217/imt.10.95","title":"Cross-Talk between Tumor and Myeloid Cells: How to Tip the Balance in Favor of Antitumor Immunity","display_name":"Cross-Talk between Tumor and Myeloid Cells: How to Tip the Balance in Favor of Antitumor Immunity","publication_year":2010,"publication_date":"2010-12-21","ids":{"openalex":"https://openalex.org/W2149884102","doi":"https://doi.org/10.2217/imt.10.95","mag":"2149884102","pmid":"https://pubmed.ncbi.nlm.nih.gov/21174559"},"language":"en","primary_location":{"id":"doi:10.2217/imt.10.95","doi":"https://doi.org/10.2217/imt.10.95","is_oa":false,"landing_page_url":"https://doi.org/10.2217/imt.10.95","pdf_url":null,"source":{"id":"https://openalex.org/S71887004","display_name":"Immunotherapy","issn_l":"1750-743X","issn":["1750-743X","1750-7448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunotherapy","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5090840799","display_name":"Jelle J. Lindenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387152927","display_name":"Cancer Center Amsterdam","ror":"https://ror.org/0286p1c86","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4387152927"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Jelle J Lindenberg","raw_affiliation_strings":["Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:","institution_ids":["https://openalex.org/I4387152927","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091791363","display_name":"Cynthia M. Fehres","orcid":"https://orcid.org/0000-0001-9020-1591","observed_orcids":["https://orcid.org/0000-0001-9020-1591"]},"institutions":[{"id":"https://openalex.org/I4387152927","display_name":"Cancer Center Amsterdam","ror":"https://ror.org/0286p1c86","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4387152927"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Cynthia M Fehres","raw_affiliation_strings":["Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:","institution_ids":["https://openalex.org/I4387152927","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030149872","display_name":"Hester van Cruijsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4387152927","display_name":"Cancer Center Amsterdam","ror":"https://ror.org/0286p1c86","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4387152927"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Hester van Cruijsen","raw_affiliation_strings":["Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:","institution_ids":["https://openalex.org/I4387152927","https://openalex.org/I911458345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059098786","display_name":"Dinja Oosterhoff","orcid":"https://orcid.org/0000-0001-8707-2266","observed_orcids":["https://orcid.org/0000-0001-8707-2266"]},"institutions":[{"id":"https://openalex.org/I4387152927","display_name":"Cancer Center Amsterdam","ror":"https://ror.org/0286p1c86","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4387152927"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Dinja Oosterhoff","raw_affiliation_strings":["Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:","institution_ids":["https://openalex.org/I4387152927","https://openalex.org/I911458345"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053105927","display_name":"Tanja D. de Gruijl","orcid":"https://orcid.org/0000-0003-1464-8978","observed_orcids":["https://orcid.org/0000-0003-1464-8978"]},"institutions":[{"id":"https://openalex.org/I4387152927","display_name":"Cancer Center Amsterdam","ror":"https://ror.org/0286p1c86","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4387152927"]},{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Tanja D de Gruijl","raw_affiliation_strings":["Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Immunotherapy Laboratory, VU University Medical Center\r CCA2.22, De Boelelaan 1117, 1081HVAmsterdam, The Netherlands Tel.: Fax:","institution_ids":["https://openalex.org/I4387152927","https://openalex.org/I911458345"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4051,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.38246575,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"3","issue":"1","first_page":"77","last_page":"96"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myeloid-cells","display_name":"myeloid cells","score":0.8700000047683716},{"id":"https://openalex.org/keywords/myeloid-derived-suppressor-cells","display_name":"myeloid-derived suppressor cells","score":0.9559999704360962},{"id":"https://openalex.org/keywords/tumor-associated-macrophages","display_name":"tumor-associated macrophages","score":0.7429999709129333},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.7350000143051147},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.8259999752044678},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.8709999918937683},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.578000009059906},{"id":"https://openalex.org/keywords/granulocytes","display_name":"granulocytes","score":0.6629999876022339},{"id":"https://openalex.org/keywords/myeloid-differentiation","display_name":"myeloid differentiation","score":0.7210000157356262},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.8185437917709351},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6393574476242065},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6270977258682251},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.5912992358207703},{"id":"https://openalex.org/C2994430510","wikidata":"https://www.wikidata.org/wiki/Q3270846","display_name":"Myeloid cells","level":3,"score":0.5634682774543762},{"id":"https://openalex.org/C95862172","wikidata":"https://www.wikidata.org/wiki/Q9032597","display_name":"Myelopoiesis","level":4,"score":0.5231719613075256},{"id":"https://openalex.org/C55721878","wikidata":"https://www.wikidata.org/wiki/Q15220362","display_name":"Myeloid-derived Suppressor Cell","level":4,"score":0.4523228406906128},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.444872111082077},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42905882000923157},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.35803693532943726},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.345132440328598},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.1925528645515442},{"id":"https://openalex.org/C179185449","wikidata":"https://www.wikidata.org/wiki/Q219699","display_name":"Suppressor","level":3,"score":0.18623566627502441},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.1637326180934906},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.14577582478523254},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002450","descriptor_name":"Cell Communication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007111","descriptor_name":"Immunity, Cellular","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007165","descriptor_name":"Immunosuppression Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D022423","descriptor_name":"Myeloid Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D022423","descriptor_name":"Myeloid Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.2217/imt.10.95","doi":"https://doi.org/10.2217/imt.10.95","is_oa":false,"landing_page_url":"https://doi.org/10.2217/imt.10.95","pdf_url":null,"source":{"id":"https://openalex.org/S71887004","display_name":"Immunotherapy","issn_l":"1750-743X","issn":["1750-743X","1750-7448"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310321119","host_organization_name":"Future Medicine","host_organization_lineage":["https://openalex.org/P4310321119"],"host_organization_lineage_names":["Future Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunotherapy","raw_type":"journal-article"},{"id":"pmid:21174559","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21174559","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunotherapy","raw_type":"Journal Article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire_cris_publications/63d16df6-81ef-4bea-92d8-1cedaa9d1d10","doi":null,"is_oa":false,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/63d16df6-81ef-4bea-92d8-1cedaa9d1d10","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Lindenberg, J J, Fehres, C M, van Cruijsen, H, Oosterhoff, D & de Gruijl, T D 2011, 'Cross-talk between tumor and myeloid cells: how to tip the balance in favor of antitumor immunity', Immunotherapy, vol. 3, no. 1, pp. 77-96. https://doi.org/10.2217/imt.10.95","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:vumc:oai:pure.atira.dk:publications/ce5ddbab-ae27-4d65-9a9d-1bf66861c4d1","doi":null,"is_oa":false,"landing_page_url":"https://research.vumc.nl/en/publications/ce5ddbab-ae27-4d65-9a9d-1bf66861c4d1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Immunotherapy, 3(1), 77 - 96. Future Medicine Ltd.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6065351856","display_name":null,"funder_award_id":"917\u2013956\u201332","funder_id":"https://openalex.org/F4320321800","funder_display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek"}],"funders":[{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":185,"referenced_works":["https://openalex.org/W193748226","https://openalex.org/W1480357432","https://openalex.org/W1494453913","https://openalex.org/W1497429764","https://openalex.org/W1503844819","https://openalex.org/W1505516118","https://openalex.org/W1507967463","https://openalex.org/W1526905466","https://openalex.org/W1533240983","https://openalex.org/W1534491890","https://openalex.org/W1538035820","https://openalex.org/W1550111480","https://openalex.org/W1554092090","https://openalex.org/W1562210554","https://openalex.org/W1580678794","https://openalex.org/W1581761477","https://openalex.org/W1585754595","https://openalex.org/W1608750708","https://openalex.org/W1636670860","https://openalex.org/W1661544713","https://openalex.org/W1838939739","https://openalex.org/W1851301117","https://openalex.org/W1877245175","https://openalex.org/W1915413180","https://openalex.org/W1925817305","https://openalex.org/W1937850172","https://openalex.org/W1943182047","https://openalex.org/W1947375451","https://openalex.org/W1960538598","https://openalex.org/W1960585934","https://openalex.org/W1966577330","https://openalex.org/W1966999437","https://openalex.org/W1967587727","https://openalex.org/W1970463098","https://openalex.org/W1970555184","https://openalex.org/W1972274031","https://openalex.org/W1976527118","https://openalex.org/W1978139448","https://openalex.org/W1978842513","https://openalex.org/W1980241157","https://openalex.org/W1980340532","https://openalex.org/W1984133971","https://openalex.org/W1985105495","https://openalex.org/W1985317418","https://openalex.org/W1986434780","https://openalex.org/W1987260005","https://openalex.org/W1987446429","https://openalex.org/W1987520066","https://openalex.org/W1987561330","https://openalex.org/W1987611102","https://openalex.org/W1992439632","https://openalex.org/W1993340690","https://openalex.org/W1994051630","https://openalex.org/W1994812075","https://openalex.org/W1998984120","https://openalex.org/W1999468766","https://openalex.org/W1999601075","https://openalex.org/W2001717792","https://openalex.org/W2004044996","https://openalex.org/W2004150448","https://openalex.org/W2004445332","https://openalex.org/W2006514214","https://openalex.org/W2006626672","https://openalex.org/W2007503046","https://openalex.org/W2011627030","https://openalex.org/W2013394982","https://openalex.org/W2015141049","https://openalex.org/W2017437032","https://openalex.org/W2021165321","https://openalex.org/W2021268612","https://openalex.org/W2022170158","https://openalex.org/W2023164440","https://openalex.org/W2023630853","https://openalex.org/W2032724602","https://openalex.org/W2032769992","https://openalex.org/W2033220681","https://openalex.org/W2034269086","https://openalex.org/W2038918212","https://openalex.org/W2039248453","https://openalex.org/W2040695321","https://openalex.org/W2043044740","https://openalex.org/W2044269184","https://openalex.org/W2044298213","https://openalex.org/W2051657147","https://openalex.org/W2052195653","https://openalex.org/W2054246680","https://openalex.org/W2054581136","https://openalex.org/W2054728198","https://openalex.org/W2059492353","https://openalex.org/W2059688175","https://openalex.org/W2059762191","https://openalex.org/W2059971077","https://openalex.org/W2061813567","https://openalex.org/W2064840117","https://openalex.org/W2065743017","https://openalex.org/W2067950819","https://openalex.org/W2067971586","https://openalex.org/W2068971398","https://openalex.org/W2069891242","https://openalex.org/W2071864881","https://openalex.org/W2073388716","https://openalex.org/W2073464835","https://openalex.org/W2075727474","https://openalex.org/W2075869202","https://openalex.org/W2077649286","https://openalex.org/W2079068389","https://openalex.org/W2079093197","https://openalex.org/W2079515223","https://openalex.org/W2079715612","https://openalex.org/W2081003674","https://openalex.org/W2084604753","https://openalex.org/W2088571368","https://openalex.org/W2089153751","https://openalex.org/W2089164228","https://openalex.org/W2094616018","https://openalex.org/W2096890213","https://openalex.org/W2097633205","https://openalex.org/W2100834680","https://openalex.org/W2101113740","https://openalex.org/W2107130188","https://openalex.org/W2108273635","https://openalex.org/W2110271242","https://openalex.org/W2111415894","https://openalex.org/W2115674896","https://openalex.org/W2116291089","https://openalex.org/W2116471973","https://openalex.org/W2116554142","https://openalex.org/W2117253810","https://openalex.org/W2117576368","https://openalex.org/W2118325137","https://openalex.org/W2119077297","https://openalex.org/W2119897005","https://openalex.org/W2120315525","https://openalex.org/W2120539661","https://openalex.org/W2121263015","https://openalex.org/W2123105952","https://openalex.org/W2124303254","https://openalex.org/W2125051557","https://openalex.org/W2125533152","https://openalex.org/W2126503106","https://openalex.org/W2126882378","https://openalex.org/W2126889178","https://openalex.org/W2130870648","https://openalex.org/W2132132140","https://openalex.org/W2134401635","https://openalex.org/W2134421457","https://openalex.org/W2135627690","https://openalex.org/W2138170994","https://openalex.org/W2138654133","https://openalex.org/W2139806485","https://openalex.org/W2140109386","https://openalex.org/W2140368744","https://openalex.org/W2141748646","https://openalex.org/W2142433114","https://openalex.org/W2145431452","https://openalex.org/W2146062596","https://openalex.org/W2146437446","https://openalex.org/W2146456208","https://openalex.org/W2150678612","https://openalex.org/W2151305294","https://openalex.org/W2152765064","https://openalex.org/W2153790270","https://openalex.org/W2153890343","https://openalex.org/W2154755100","https://openalex.org/W2155402153","https://openalex.org/W2157269800","https://openalex.org/W2157769714","https://openalex.org/W2158853057","https://openalex.org/W2162047243","https://openalex.org/W2163242247","https://openalex.org/W2163825883","https://openalex.org/W2165028688","https://openalex.org/W2165064029","https://openalex.org/W2165330900","https://openalex.org/W2166732256","https://openalex.org/W2168428587","https://openalex.org/W2168478794","https://openalex.org/W2169979796","https://openalex.org/W2170123390","https://openalex.org/W2275872217","https://openalex.org/W2323921384","https://openalex.org/W2335128695","https://openalex.org/W2351521556","https://openalex.org/W2418106759","https://openalex.org/W2593611879"],"related_works":["https://openalex.org/W2979721021","https://openalex.org/W3132544335","https://openalex.org/W4412774953","https://openalex.org/W2036112796","https://openalex.org/W2231886960","https://openalex.org/W4406202489","https://openalex.org/W2015904992","https://openalex.org/W4297243288","https://openalex.org/W2157269800","https://openalex.org/W2001014417"],"abstract_inverted_index":{"Myeloid":[0],"differentiation":[1],"is":[2],"often":[3],"disturbed":[4],"in":[5,60,84,100,120],"cancer,":[6],"leading":[7],"to":[8,54,116],"reduced":[9],"frequencies":[10],"of":[11,18,29,64,75,122],"immunostimulatory":[12],"dendritic":[13],"cells":[14,47],"and":[15,24,68,81,94,98],"an":[16,61],"over-representation":[17],"immunosuppressive":[19,36],"immature":[20],"myeloid":[21,32,37,78,96],"cells,":[22],"granulocytes":[23],"macrophages.":[25],"As":[26],"a":[27,34,52],"result":[28],"this":[30,72],"skewed":[31],"differentiation,":[33],"highly":[35],"subset":[38],"becomes":[39],"prevalent":[40],"during":[41],"cancer":[42],"development;":[43],"these":[44],"myeloid-derived":[45],"suppressor":[46],"are":[48,88,108],"also":[49],"recruited":[50],"as":[51,110,112],"collateral":[53],"certain":[55],"protumorigenic":[56],"inflammatory":[57],"processes,":[58],"resulting":[59],"effective":[62,105],"downregulation":[63],"T-cell-mediated":[65],"immune":[66,86],"surveillance":[67],"antitumor":[69,123],"immunity.":[70,124],"In":[71],"article,":[73],"some":[74],"the":[76,95,118],"important":[77],"cell":[79],"subsets":[80],"mediators":[82],"involved":[83],"cancer-related":[85],"suppression":[87],"reviewed.":[89],"Furthermore,":[90],"cross-talk":[91],"between":[92],"tumors":[93],"compartment,":[97],"ways":[99],"which":[101],"it":[102],"can":[103],"suppress":[104],"cell-mediated":[106],"immunity,":[107],"discussed,":[109],"well":[111],"possible":[113],"therapeutic":[114],"approaches":[115],"tip":[117],"balance":[119],"favor":[121]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}