{"id":"https://openalex.org/W2149795345","doi":"https://doi.org/10.1128/jcm.02113-09","title":"GeneXpert Captures Unstable Methicillin-Resistant Staphylococcus aureus Prone to Rapidly Losing the mecA Gene","display_name":"GeneXpert Captures Unstable Methicillin-Resistant Staphylococcus aureus Prone to Rapidly Losing the mecA Gene","publication_year":2010,"publication_date":"2010-06-10","ids":{"openalex":"https://openalex.org/W2149795345","doi":"https://doi.org/10.1128/jcm.02113-09","mag":"2149795345","pmid":"https://pubmed.ncbi.nlm.nih.gov/20534797","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2916610"},"language":"en","primary_location":{"id":"doi:10.1128/jcm.02113-09","doi":"https://doi.org/10.1128/jcm.02113-09","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jcm.02113-09","pdf_url":null,"source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2916610","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024504258","display_name":"Diana Ciardo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Diana E. Ciardo","raw_affiliation_strings":["Institute of Medical Microbiology, University of Zu\u0308rich, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Microbiology, University of Zu\u0308rich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000670752","display_name":"Sibylle B\u00fcrger","orcid":"https://orcid.org/0009-0001-8861-0959","observed_orcids":["https://orcid.org/0009-0001-8861-0959"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sibylle Burger","raw_affiliation_strings":["Institute of Medical Microbiology, University of Zu\u0308rich, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Microbiology, University of Zu\u0308rich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael Payer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098738","display_name":"Klinik Hirslanden","ror":"https://ror.org/014c2qb55","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I4210098738","https://openalex.org/I4210110334"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Michael Payer","raw_affiliation_strings":["NeuroZentrum Hirslanden, Zu\u0308rich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NeuroZentrum Hirslanden, Zu\u0308rich, Switzerland","institution_ids":["https://openalex.org/I4210098738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012841445","display_name":"Christian R. Lee","orcid":"https://orcid.org/0000-0003-2475-9567","observed_orcids":["https://orcid.org/0000-0003-2475-9567"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian Lee","raw_affiliation_strings":["Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026726105","display_name":"Nadine Holmes","orcid":"https://orcid.org/0000-0001-7470-3786","observed_orcids":["https://orcid.org/0000-0001-7470-3786"]},"institutions":[{"id":"https://openalex.org/I202697423","display_name":"University of Zurich","ror":"https://ror.org/02crff812","country_code":"CH","type":"education","lineage":["https://openalex.org/I202697423"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Nadine McCallum","raw_affiliation_strings":["Institute of Medical Microbiology, University of Zu\u0308rich, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Medical Microbiology, University of Zu\u0308rich, Zurich, Switzerland","institution_ids":["https://openalex.org/I202697423"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4132,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.68488189,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"48","issue":"8","first_page":"3030","last_page":"3032"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/methicillin-resistant-staphylococcus-aureus","display_name":"methicillin-resistant Staphylococcus aureus","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cefoxitin-susceptibility","display_name":"cefoxitin susceptibility","score":0.8640000224113464},{"id":"https://openalex.org/keywords/genexpert","display_name":"GeneXpert","score":0.800000011920929}],"concepts":[{"id":"https://openalex.org/C2776124114","wikidata":"https://www.wikidata.org/wiki/Q2353907","display_name":"Cefoxitin","level":4,"score":0.9402880668640137},{"id":"https://openalex.org/C126265401","wikidata":"https://www.wikidata.org/wiki/Q295544","display_name":"GeneXpert MTB/RIF","level":4,"score":0.9230375289916992},{"id":"https://openalex.org/C11701158","wikidata":"https://www.wikidata.org/wiki/Q7389099","display_name":"SCCmec","level":5,"score":0.8622927665710449},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.8489727973937988},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7777749300003052},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.4715564250946045},{"id":"https://openalex.org/C2775965595","wikidata":"https://www.wikidata.org/wiki/Q1365581","display_name":"Micrococcaceae","level":4,"score":0.4652235209941864},{"id":"https://openalex.org/C2777052132","wikidata":"https://www.wikidata.org/wiki/Q595158","display_name":"Methicillin-resistant Staphylococcus aureus","level":4,"score":0.44902336597442627},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44838640093803406},{"id":"https://openalex.org/C2776540679","wikidata":"https://www.wikidata.org/wiki/Q409262","display_name":"Meticillin","level":5,"score":0.44080257415771484},{"id":"https://openalex.org/C3019249092","wikidata":"https://www.wikidata.org/wiki/Q274493","display_name":"Antibacterial agent","level":3,"score":0.36818426847457886},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.33063793182373047},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27581724524497986},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.2557392120361328},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.22415828704833984},{"id":"https://openalex.org/C2776301714","wikidata":"https://www.wikidata.org/wiki/Q259346","display_name":"Sputum","level":3,"score":0.11363089084625244},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10629656910896301},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.08548524975776672},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001431","descriptor_name":"Bacteriological Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002440","descriptor_name":"Cefoxitin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004269","descriptor_name":"DNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008826","descriptor_name":"Microbial Sensitivity Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D016172","descriptor_name":"DNA Fingerprinting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016521","descriptor_name":"Electrophoresis, Gel, Pulsed-Field","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042822","descriptor_name":"Genomic Instability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046915","descriptor_name":"Penicillin-Binding Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055624","descriptor_name":"Methicillin-Resistant Staphylococcus aureus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D055624","descriptor_name":"Methicillin-Resistant Staphylococcus aureus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055624","descriptor_name":"Methicillin-Resistant Staphylococcus aureus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D055624","descriptor_name":"Methicillin-Resistant Staphylococcus aureus","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1128/jcm.02113-09","doi":"https://doi.org/10.1128/jcm.02113-09","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jcm.02113-09","pdf_url":null,"source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2916610","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2916610","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Microbiol","raw_type":"Text"},{"id":"pmid:20534797","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20534797","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical microbiology","raw_type":"Case Reports"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1027.6997","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1027.6997","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://jcm.asm.org/content/48/8/3030.full.pdf","raw_type":"text"},{"id":"pmh:oai:www.zora.uzh.ch:20.500.14742/55396","doi":null,"is_oa":false,"landing_page_url":"https://www.zora.uzh.ch/handle/20.500.14742/55396","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ciardo, D. E., Burger, S., Payer, M., Lee, C., & McCallum, N. (2010). GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene. Journal of Clinical Microbiology, 48, 3030\u20133032. https://doi.org/10.1128/JCM.02113-09","raw_type":"Journal Article"},{"id":"pmh:oai:www.zora.uzh.ch:39792","doi":null,"is_oa":false,"landing_page_url":"https://www.zora.uzh.ch/39792","pdf_url":null,"source":{"id":"https://openalex.org/S4306401281","display_name":"Zurich Open Repository and Archive (University of Zurich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I202697423","host_organization_name":"University of Zurich","host_organization_lineage":["https://openalex.org/I202697423"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ciardo, D E; Burger, S; Payer, M; Lee, C; McCallum, N (2010). GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene. Journal of Clinical Microbiology, 48(8):3030-3032.","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2916610","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2916610","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Microbiol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1991869606","https://openalex.org/W1996396935","https://openalex.org/W2011376880","https://openalex.org/W2014171691","https://openalex.org/W2014661840","https://openalex.org/W2015108672","https://openalex.org/W2052097677","https://openalex.org/W2084675205","https://openalex.org/W2106340396","https://openalex.org/W2124280634","https://openalex.org/W2127608640","https://openalex.org/W2137362472","https://openalex.org/W2137403564","https://openalex.org/W2137499186","https://openalex.org/W2140776507","https://openalex.org/W2149425658","https://openalex.org/W2161836519","https://openalex.org/W2163801401","https://openalex.org/W2168482920","https://openalex.org/W2169653227"],"related_works":["https://openalex.org/W1051142226","https://openalex.org/W2945025158","https://openalex.org/W2332232951","https://openalex.org/W2038612789","https://openalex.org/W3038404845","https://openalex.org/W2620319976","https://openalex.org/W2605760967","https://openalex.org/W3158321995","https://openalex.org/W3151996172","https://openalex.org/W2107666000"],"abstract_inverted_index":{"A":[0],"cefoxitin-susceptible":[1],"Staphylococcus":[2],"aureus":[3,14],"strain":[4,17],"was":[5,18],"identified":[6],"by":[7,36],"the":[8],"Cepheid":[9],"GeneXpert":[10],"as":[11],"methicillin-resistant":[12],"S.":[13],"(MRSA).":[15],"This":[16],"highly":[19],"unstable":[20,31],"and":[21],"rapidly":[22],"lost":[23],"SCCmec":[24],"upon":[25],"subculturing":[26],"in":[27],"vitro,":[28],"indicating":[29],"that":[30],"MRSA":[32],"is":[33],"best":[34],"detected":[35],"gene":[37],"amplification-based":[38],"methods.":[39]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}