{"id":"https://openalex.org/W2149780343","doi":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","title":"Der(6)t(1;6)(q21\u201323;p21.3): a specific cytogenetic abnormality in myelofibrosis with myeloid metaplasia","display_name":"Der(6)t(1;6)(q21\u201323;p21.3): a specific cytogenetic abnormality in myelofibrosis with myeloid metaplasia","publication_year":2005,"publication_date":"2005-06-28","ids":{"openalex":"https://openalex.org/W2149780343","doi":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","mag":"2149780343","pmid":"https://pubmed.ncbi.nlm.nih.gov/16029451"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-2141.2005.05593.x","doi":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2141.2005.05593.x","source":{"id":"https://openalex.org/S153015021","display_name":"British Journal of Haematology","issn_l":"0007-1048","issn":["0007-1048","1365-2141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Haematology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2141.2005.05593.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007747233","display_name":"David Dingli","orcid":"https://orcid.org/0000-0001-7477-3004","observed_orcids":["https://orcid.org/0000-0001-7477-3004"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Dingli","raw_affiliation_strings":["Division of Hematology and Department of Internal Medicine, Mayo Clinic Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Department of Internal Medicine, Mayo Clinic Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112436254","display_name":"Francis Grand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799594651","display_name":"Salisbury District Hospital","ror":"https://ror.org/05bx2yj81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799594651","https://openalex.org/I79209787"]},{"id":"https://openalex.org/I4210129558","display_name":"Wessex Regional Genetics Laboratory","ror":"https://ror.org/02t83f864","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210129558","https://openalex.org/I79209787"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Francis H. Grand","raw_affiliation_strings":["Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, and Human Genetics Division, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, and Human Genetics Division, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I2799594651","https://openalex.org/I4210129558","https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053976569","display_name":"Victor J. Mahaffey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Victor Mahaffey","raw_affiliation_strings":["Cytogenetics Laboratory, Department of Internal Medicine and Pathology, Mayo Clinic Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytogenetics Laboratory, Department of Internal Medicine and Pathology, Mayo Clinic Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058960055","display_name":"Jack L. Spurbeck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jack Spurbeck","raw_affiliation_strings":["Cytogenetics Laboratory, Department of Internal Medicine and Pathology, Mayo Clinic Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytogenetics Laboratory, Department of Internal Medicine and Pathology, Mayo Clinic Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109919329","display_name":"Fiona M. Ross","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799594651","display_name":"Salisbury District Hospital","ror":"https://ror.org/05bx2yj81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799594651","https://openalex.org/I79209787"]},{"id":"https://openalex.org/I4210129558","display_name":"Wessex Regional Genetics Laboratory","ror":"https://ror.org/02t83f864","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210129558","https://openalex.org/I79209787"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Fiona M. Ross","raw_affiliation_strings":["Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, and Human Genetics Division, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, and Human Genetics Division, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I2799594651","https://openalex.org/I4210129558","https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045977249","display_name":"Ann E. Watmore","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801732343","display_name":"Royal Hallamshire Hospital","ror":"https://ror.org/00514rc81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801732343","https://openalex.org/I4210102902"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ann E. Watmore","raw_affiliation_strings":["Academic Unit of Haematology, Division of Genomic Medicine, Royal Hallamshire Hospital, Sheffield, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academic Unit of Haematology, Division of Genomic Medicine, Royal Hallamshire Hospital, Sheffield, UK","institution_ids":["https://openalex.org/I2801732343"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113501418","display_name":"John T. Reilly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801732343","display_name":"Royal Hallamshire Hospital","ror":"https://ror.org/00514rc81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2801732343","https://openalex.org/I4210102902"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John T. Reilly","raw_affiliation_strings":["Academic Unit of Haematology, Division of Genomic Medicine, Royal Hallamshire Hospital, Sheffield, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academic Unit of Haematology, Division of Genomic Medicine, Royal Hallamshire Hospital, Sheffield, UK","institution_ids":["https://openalex.org/I2801732343"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036839901","display_name":"Nicholas C.P. Cross","orcid":"https://orcid.org/0000-0001-5481-2555","observed_orcids":["https://orcid.org/0000-0001-5481-2555"]},"institutions":[{"id":"https://openalex.org/I2799594651","display_name":"Salisbury District Hospital","ror":"https://ror.org/05bx2yj81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799594651","https://openalex.org/I79209787"]},{"id":"https://openalex.org/I4210129558","display_name":"Wessex Regional Genetics Laboratory","ror":"https://ror.org/02t83f864","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210129558","https://openalex.org/I79209787"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nicholas C. P. Cross","raw_affiliation_strings":["Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, and Human Genetics Division, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Wessex Regional Genetics Laboratory, Salisbury District Hospital, Salisbury, and Human Genetics Division, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I2799594651","https://openalex.org/I4210129558","https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113542194","display_name":"Gordon W. Dewald","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon W. Dewald","raw_affiliation_strings":["Cytogenetics Laboratory, Department of Internal Medicine and Pathology, Mayo Clinic Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cytogenetics Laboratory, Department of Internal Medicine and Pathology, Mayo Clinic Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016216479","display_name":"Ayalew Tefferi","orcid":"https://orcid.org/0000-0003-4605-3821","observed_orcids":["https://orcid.org/0000-0003-4605-3821"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ayalew Tefferi","raw_affiliation_strings":["Division of Hematology and Department of Internal Medicine, Mayo Clinic Rochester, MN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology and Department of Internal Medicine, Mayo Clinic Rochester, MN, USA","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5016216479"],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":{"value":5190,"currency":"USD","value_usd":5190},"apc_paid":null,"fwci":2.1191,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.88965612,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"130","issue":"2","first_page":"229","last_page":"232"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13374","display_name":"Hematological disorders and diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/myelofibrosis-with-myeloid-metaplasia","display_name":"myelofibrosis with myeloid metaplasia","score":0.9800000190734863},{"id":"https://openalex.org/keywords/unbalanced-translocation","display_name":"unbalanced translocation","score":0.8140000104904175},{"id":"https://openalex.org/keywords/chromosomal-abnormalities","display_name":"chromosomal abnormalities","score":0.8040000200271606},{"id":"https://openalex.org/keywords/fkbp51","display_name":"FKBP51","score":0.7630000114440918},{"id":"https://openalex.org/keywords/fluorescence-in-situ-hybridization","display_name":"fluorescence in situ hybridization","score":0.7099999785423279},{"id":"https://openalex.org/keywords/survival","display_name":"survival","score":0.36000001430511475},{"id":"https://openalex.org/keywords/clinical-phenotype","display_name":"clinical phenotype","score":0.6510000228881836}],"concepts":[{"id":"https://openalex.org/C2780076729","wikidata":"https://www.wikidata.org/wiki/Q1752571","display_name":"Myelofibrosis","level":3,"score":0.8208017349243164},{"id":"https://openalex.org/C174475383","wikidata":"https://www.wikidata.org/wiki/Q246128","display_name":"Cytogenetics","level":4,"score":0.635968804359436},{"id":"https://openalex.org/C2777542201","wikidata":"https://www.wikidata.org/wiki/Q1336182","display_name":"Fluorescence in situ hybridization","level":4,"score":0.6079161763191223},{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.58652263879776},{"id":"https://openalex.org/C206936463","wikidata":"https://www.wikidata.org/wiki/Q634179","display_name":"Breakpoint","level":4,"score":0.5564214587211609},{"id":"https://openalex.org/C2779357193","wikidata":"https://www.wikidata.org/wiki/Q660713","display_name":"Metaplasia","level":2,"score":0.4899258017539978},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.473949670791626},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4396026134490967},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.4343802332878113},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.4198577105998993},{"id":"https://openalex.org/C2780189214","wikidata":"https://www.wikidata.org/wiki/Q744962","display_name":"Chromosome abnormality","level":5,"score":0.4129437208175659},{"id":"https://openalex.org/C53226629","wikidata":"https://www.wikidata.org/wiki/Q189967","display_name":"Karyotype","level":4,"score":0.4102691113948822},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3888700306415558},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.32617419958114624},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3246668577194214},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2578190863132477},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.25223618745803833},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.1548662781715393}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002878","descriptor_name":"Chromosomes, Human, Pair 1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002896","descriptor_name":"Chromosomes, Human, Pair 6","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007621","descriptor_name":"Karyotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014178","descriptor_name":"Translocation, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019457","descriptor_name":"Chromosome Breakage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055728","descriptor_name":"Primary Myelofibrosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1111/j.1365-2141.2005.05593.x","doi":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2141.2005.05593.x","source":{"id":"https://openalex.org/S153015021","display_name":"British Journal of Haematology","issn_l":"0007-1048","issn":["0007-1048","1365-2141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Haematology","raw_type":"journal-article"},{"id":"pmid:16029451","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16029451","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of haematology","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.soton.ac.uk:24685","doi":null,"is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/24685/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1111/j.1365-2141.2005.05593.x","doi":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-2141.2005.05593.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2141.2005.05593.x","source":{"id":"https://openalex.org/S153015021","display_name":"British Journal of Haematology","issn_l":"0007-1048","issn":["0007-1048","1365-2141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Haematology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2149780343.pdf","grobid_xml":"https://content.openalex.org/works/W2149780343.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W25741254","https://openalex.org/W117227893","https://openalex.org/W1973560711","https://openalex.org/W1980464575","https://openalex.org/W1989127893","https://openalex.org/W1993222445","https://openalex.org/W1994796625","https://openalex.org/W2002112267","https://openalex.org/W2006321868","https://openalex.org/W2010809238","https://openalex.org/W2020649382","https://openalex.org/W2035834633","https://openalex.org/W2059132989","https://openalex.org/W2060329260","https://openalex.org/W2061724544","https://openalex.org/W2073653195","https://openalex.org/W2090370198","https://openalex.org/W2114419137","https://openalex.org/W2116686499","https://openalex.org/W2127960825","https://openalex.org/W2138148984","https://openalex.org/W2172222625","https://openalex.org/W2326795317","https://openalex.org/W2409651431","https://openalex.org/W2410113373","https://openalex.org/W2417298854"],"related_works":["https://openalex.org/W2279451582","https://openalex.org/W2073653195","https://openalex.org/W1995335105","https://openalex.org/W1985027763","https://openalex.org/W2020356421","https://openalex.org/W2053555969","https://openalex.org/W2094554598","https://openalex.org/W2008379494","https://openalex.org/W2082020145","https://openalex.org/W2085920715"],"abstract_inverted_index":{"Chromosome":[0],"anomalies":[1],"are":[2,22],"detected":[3],"in":[4,80,128,137],"approximately":[5],"half":[6],"of":[7,17,32,97,103],"patients":[8,34,62,86,100],"with":[9,11,35,40,49,63,122],"myelofibrosis":[10],"myeloid":[12],"metaplasia":[13],"(MMM)":[14],"although":[15],"none":[16],"the":[18,25,132,147],"most":[19],"prevalent":[20],"lesions":[21],"specific":[23,50,113],"to":[24,143,146],"disease.":[26],"In":[27,124],"a":[28,111,125],"prospective":[29],"cytogenetic":[30,57,114],"study":[31],"81":[33],"MMM,":[36],"we":[37],"encountered":[38],"three":[39],"an":[41],"unbalanced":[42],"translocation":[43],"between":[44],"chromosomes":[45],"1":[46],"and":[47,93],"6":[48,136],"breakpoints;":[51],"der(6)t(1;6)(q21-23;p21.3).":[52],"A":[53,72],"subsequent":[54],"Mayo":[55],"Clinic":[56],"database":[58,74],"search":[59,75],"identified":[60],"12":[61],"this":[64],"chromosome":[65,135],"anomaly":[66,115],"among":[67,87],"17":[68],"791":[69],"consecutive":[70],"patients.":[71],"similar":[73],"from":[76],"Royal":[77],"Hallamshire":[78],"Hospital":[79],"Sheffield,":[81],"UK":[82],"revealed":[83],"two":[84,138],"additional":[85,139],"8000":[88],"cases.":[89],"The":[90],"clinical":[91],"phenotype":[92],"survival":[94],"for":[95,149],"each":[96],"these":[98],"14":[99],"was":[101],"typical":[102],"MMM.":[104,123],"These":[105],"findings":[106],"suggested":[107],"that":[108,116],"der(6)t(1;6)(q21-23;p21.3)":[109],"is":[110],"highly":[112],"may":[117],"harbour":[118],"gene(s)":[119],"specifically":[120],"associated":[121],"preliminary":[126],"fluorescence":[127],"situ":[129],"hybridization":[130],"study,":[131],"breakpoints":[133],"on":[134],"cases":[140],"were":[141],"found":[142],"be":[144],"telomeric":[145],"gene":[148],"51":[150],"kDa":[151],"FK506-binding":[152],"protein":[153],"(FKBP51).":[154]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}