{"id":"https://openalex.org/W2149759298","doi":"https://doi.org/10.1158/2159-8274.cd-11-0042","title":"Epidemiology\u2014Found in Translation","display_name":"Epidemiology\u2014Found in Translation","publication_year":2011,"publication_date":"2011-04-08","ids":{"openalex":"https://openalex.org/W2149759298","doi":"https://doi.org/10.1158/2159-8274.cd-11-0042","mag":"2149759298","pmid":"https://pubmed.ncbi.nlm.nih.gov/22586315"},"language":"en","primary_location":{"id":"doi:10.1158/2159-8274.cd-11-0042","doi":"https://doi.org/10.1158/2159-8274.cd-11-0042","is_oa":false,"landing_page_url":"https://doi.org/10.1158/2159-8274.cd-11-0042","pdf_url":null,"source":{"id":"https://openalex.org/S2486275289","display_name":"Cancer Discovery","issn_l":"2159-8274","issn":["2159-8274","2159-8290"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Discovery","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109231357","display_name":"Margaret R. Spitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4390039366","display_name":"Dan L Duncan Comprehensive Cancer Center","ror":"https://ror.org/02nre0x31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370","https://openalex.org/I4390039366"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret R. Spitz","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, The University of Texas MD Anderson Cancer Center, and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; 2Division of Cancer Epidemiology and Genetics and 3Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, The University of Texas MD Anderson Cancer Center, and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; 2Division of Cancer Epidemiology and Genetics and 3Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, Maryland","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I181547552","https://openalex.org/I4210140884","https://openalex.org/I4390039366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019329822","display_name":"Neil E. Caporaso","orcid":"https://orcid.org/0000-0001-7562-4609","observed_orcids":["https://orcid.org/0000-0001-7562-4609"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4390039366","display_name":"Dan L Duncan Comprehensive Cancer Center","ror":"https://ror.org/02nre0x31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370","https://openalex.org/I4390039366"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Neil E. Caporaso","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, The University of Texas MD Anderson Cancer Center, and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; 2Division of Cancer Epidemiology and Genetics and 3Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, The University of Texas MD Anderson Cancer Center, and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; 2Division of Cancer Epidemiology and Genetics and 3Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, Maryland","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I181547552","https://openalex.org/I4210140884","https://openalex.org/I4390039366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102853284","display_name":"Andrew N. Freedman","orcid":"https://orcid.org/0000-0003-1451-4208","observed_orcids":["https://orcid.org/0000-0003-1451-4208"]},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4390039366","display_name":"Dan L Duncan Comprehensive Cancer Center","ror":"https://ror.org/02nre0x31","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370","https://openalex.org/I4390039366"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew N. Freedman","raw_affiliation_strings":["Authors' Affiliations:\u20081Department of Epidemiology, The University of Texas MD Anderson Cancer Center, and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; 2Division of Cancer Epidemiology and Genetics and 3Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Authors' Affiliations:\u20081Department of Epidemiology, The University of Texas MD Anderson Cancer Center, and the Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; 2Division of Cancer Epidemiology and Genetics and 3Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Bethesda, Maryland","institution_ids":["https://openalex.org/I1343551460","https://openalex.org/I181547552","https://openalex.org/I4210140884","https://openalex.org/I4390039366"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2795,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.66446955,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"1","issue":"1","first_page":"21","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14374","display_name":"Statistical Methods in Epidemiology","score":0.3483999967575073,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14374","display_name":"Statistical Methods in Epidemiology","score":0.3483999967575073,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13656","display_name":"Science, Research, and Medicine","score":0.12349999696016312,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.09179999679327011,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/observational-epidemiology","display_name":"observational epidemiology","score":0.8320000171661377},{"id":"https://openalex.org/keywords/translational-research","display_name":"translational research","score":0.7570000290870667},{"id":"https://openalex.org/keywords/in-vitro-screening","display_name":"in vitro screening","score":0.6389999985694885},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.4180000126361847}],"concepts":[{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.7090457081794739},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.5416494011878967},{"id":"https://openalex.org/C149364088","wikidata":"https://www.wikidata.org/wiki/Q185917","display_name":"Translation (biology)","level":4,"score":0.4762311577796936},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4515296220779419},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4433860182762146},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4383486807346344},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3873046338558197},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3748074769973755},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.339114248752594},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2802996039390564},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.21518367528915405},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14743223786354065},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1429043412208557},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D004077","descriptor_name":"Digoxin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1158/2159-8274.cd-11-0042","doi":"https://doi.org/10.1158/2159-8274.cd-11-0042","is_oa":false,"landing_page_url":"https://doi.org/10.1158/2159-8274.cd-11-0042","pdf_url":null,"source":{"id":"https://openalex.org/S2486275289","display_name":"Cancer Discovery","issn_l":"2159-8274","issn":["2159-8274","2159-8290"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Discovery","raw_type":"journal-article"},{"id":"pmid:22586315","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22586315","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer discovery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1970524440","https://openalex.org/W2000902592","https://openalex.org/W2002707371","https://openalex.org/W2006825115","https://openalex.org/W2038388049","https://openalex.org/W2041488858","https://openalex.org/W2048257551","https://openalex.org/W2052000438","https://openalex.org/W2095831706","https://openalex.org/W2107859602","https://openalex.org/W2112629831","https://openalex.org/W2124517950","https://openalex.org/W2164216839"],"related_works":["https://openalex.org/W2280274405","https://openalex.org/W2552289615","https://openalex.org/W2467298918","https://openalex.org/W7100644044","https://openalex.org/W4285229852","https://openalex.org/W4388243434","https://openalex.org/W2163844151","https://openalex.org/W2123330610","https://openalex.org/W2094004178","https://openalex.org/W2945533715"],"abstract_inverted_index":{"Abstract":[0],"We":[1],"highlight":[2],"the":[3,22],"value":[4],"of":[5,39],"carefully":[6],"designed":[7],"observational":[8],"epidemiologic":[9,32],"analyses":[10],"in":[11,20,36],"translating":[12],"basic":[13],"science":[14],"discoveries":[15],"to":[16],"clinical":[17,50],"application":[18],"and":[19],"providing":[21],"impetus":[23],"for":[24,28,48],"exploring":[25],"underlying":[26],"mechanisms":[27],"observed":[29],"associations.":[30],"Coupling":[31],"data":[33],"with":[34],"an":[35],"vitro":[37],"screen":[38],"commonly":[40],"used":[41],"therapeutic":[42],"agents":[43],"may":[44],"identify":[45],"novel":[46],"applications":[47],"further":[49],"testing.":[51],"Cancer":[52],"Discovery;":[53],"1(1);":[54],"21\u20132.":[55],"\u00a92011":[56],"AACR.":[57],"Commentary":[58],"on":[59],"Platz":[60],"et":[61],"al.,":[62],"p.":[63],"68":[64]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
