{"id":"https://openalex.org/W2149642128","doi":"https://doi.org/10.1016/j.bmcl.2011.09.129","title":"Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells","display_name":"Chemical constituents of the rhizomes of Hedychium coronarium and their inhibitory effect on the pro-inflammatory cytokines production LPS-stimulated in bone marrow-derived dendritic cells","publication_year":2011,"publication_date":"2011-10-17","ids":{"openalex":"https://openalex.org/W2149642128","doi":"https://doi.org/10.1016/j.bmcl.2011.09.129","mag":"2149642128","pmid":"https://pubmed.ncbi.nlm.nih.gov/22071304"},"language":"en","primary_location":{"id":"doi:10.1016/j.bmcl.2011.09.129","doi":"https://doi.org/10.1016/j.bmcl.2011.09.129","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bmcl.2011.09.129","pdf_url":null,"source":{"id":"https://openalex.org/S30970080","display_name":"Bioorganic & Medicinal Chemistry Letters","issn_l":"0960-894X","issn":["0960-894X","1464-3405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & Medicinal Chemistry Letters","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014245013","display_name":"Phan V\u0103n Ki\u1ec7m","orcid":"https://orcid.org/0000-0003-0756-6990","observed_orcids":["https://orcid.org/0000-0003-0756-6990"]},"institutions":[{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Phan Van Kiem","raw_affiliation_strings":["Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101751915","display_name":"Nguyen Thi Thuy","orcid":"https://orcid.org/0000-0003-2342-3797","observed_orcids":["https://orcid.org/0000-0003-2342-3797"]},"institutions":[{"id":"https://openalex.org/I4210161490","display_name":"Viet Tri University of Industry","ror":"https://ror.org/059sj0146","country_code":"VN","type":"education","lineage":["https://openalex.org/I4210161490"]},{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Nguyen Thi Kim Thuy","raw_affiliation_strings":["Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","Viettri University of Industry, Viettri, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]},{"raw_affiliation_string":"Viettri University of Industry, Viettri, Viet Nam","institution_ids":["https://openalex.org/I4210161490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109582315","display_name":"Hoang Le Tuan Anh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Hoang Le Tuan Anh","raw_affiliation_strings":["Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026799941","display_name":"Nguy\u1ec5n Xu\u00e2n Nhi\u1ec7m","orcid":"https://orcid.org/0000-0002-1161-6498","observed_orcids":["https://orcid.org/0000-0002-1161-6498"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]},{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["KR","VN"],"is_corresponding":false,"raw_author_name":"Nguyen Xuan Nhiem","raw_affiliation_strings":["College of Pharmacy, Chungnam National University, Daejeon 305-764, South Korea","Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Chungnam National University, Daejeon 305-764, South Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110058124","display_name":"Ch\u00e2u V\u0103n Minh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Chau Van Minh","raw_affiliation_strings":["Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109512574","display_name":"Ph\u1ea1m H\u1ea3i Y\u1ebfn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Pham Hai Yen","raw_affiliation_strings":["Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086231905","display_name":"Ninh Kh\u1eafc B\u1ea3n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Ninh Khac Ban","raw_affiliation_strings":["Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110788444","display_name":"\u0110an Th\u1ecb Th\u00fay H\u1eb1ng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Dan Thuy Hang","raw_affiliation_strings":["Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016357695","display_name":"B\u00f9i H\u1eefu T\u00e0i","orcid":"https://orcid.org/0000-0002-2034-3786","observed_orcids":["https://orcid.org/0000-0002-2034-3786"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]},{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["KR","VN"],"is_corresponding":false,"raw_author_name":"Bui Huu Tai","raw_affiliation_strings":["College of Pharmacy, Chungnam National University, Daejeon 305-764, South Korea","Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Chungnam National University, Daejeon 305-764, South Korea","institution_ids":["https://openalex.org/I196345858"]},{"raw_affiliation_string":"Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103205999","display_name":"Nguyen Van Tuyen","orcid":"https://orcid.org/0000-0003-3694-7303","observed_orcids":["https://orcid.org/0000-0003-3694-7303"]},"institutions":[{"id":"https://openalex.org/I4405278084","display_name":"Vi\u1ec7n H\u00f3a h\u1ecdc","ror":"https://ror.org/04x07t723","country_code":"VN","type":"facility","lineage":["https://openalex.org/I4405278084"]},{"id":"https://openalex.org/I70349855","display_name":"Vietnam Academy of Science and Technology","ror":"https://ror.org/02wsd5p50","country_code":"VN","type":"government","lineage":["https://openalex.org/I70349855"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Nguyen Van Tuyen","raw_affiliation_strings":["Institute of Chemistry, VAST, 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Chemistry, VAST, 18 Hoang Quoc Viet, Caugiay, Hanoi, Viet Nam","institution_ids":["https://openalex.org/I4405278084","https://openalex.org/I70349855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020039833","display_name":"Vivek Bhakta Mathema","orcid":"https://orcid.org/0000-0003-3916-9949","observed_orcids":["https://orcid.org/0000-0003-3916-9949"]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Vivek Bhakta Mathema","raw_affiliation_strings":["School of Medicine and Brain Korea 21 Program, Jeju National University, Jeju 690-756, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine and Brain Korea 21 Program, Jeju National University, Jeju 690-756, South Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109886771","display_name":"Young\u2010Sang Koh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83202590","display_name":"Jeju National University","ror":"https://ror.org/05hnb4n85","country_code":"KR","type":"education","lineage":["https://openalex.org/I83202590"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young-Sang Koh","raw_affiliation_strings":["School of Medicine and Brain Korea 21 Program, Jeju National University, Jeju 690-756, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine and Brain Korea 21 Program, Jeju National University, Jeju 690-756, South Korea","institution_ids":["https://openalex.org/I83202590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100335103","display_name":"Young Ho Kim","orcid":"https://orcid.org/0000-0002-7441-9459","observed_orcids":["https://orcid.org/0000-0002-7441-9459","https://orcid.org/0000-0003-0703-1136","https://orcid.org/0000-0002-5212-7543","https://orcid.org/0000-0001-8431-7563"]},"institutions":[{"id":"https://openalex.org/I196345858","display_name":"Chungnam National University","ror":"https://ror.org/0227as991","country_code":"KR","type":"education","lineage":["https://openalex.org/I196345858"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Young Ho Kim","raw_affiliation_strings":["College of Pharmacy, Chungnam National University, Daejeon 305-764, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Pharmacy, Chungnam National University, Daejeon 305-764, South Korea","institution_ids":["https://openalex.org/I196345858"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100335103"],"corresponding_institution_ids":["https://openalex.org/I196345858"],"apc_list":{"value":3880,"currency":"USD","value_usd":3880},"apc_paid":null,"fwci":1.1098,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.72866751,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"21","issue":"24","first_page":"7460","last_page":"7465"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12530","display_name":"Bioactive Natural Diterpenoids Research","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12530","display_name":"Bioactive Natural Diterpenoids Research","score":0.9717000126838684,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11613","display_name":"Phytochemistry and Biological Activities","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12347","display_name":"Ginger and Zingiberaceae research","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hedychium-coronarium","display_name":"Hedychium coronarium","score":1.0},{"id":"https://openalex.org/keywords/rhizome","display_name":"rhizome","score":0.8399999737739563},{"id":"https://openalex.org/keywords/labdane-diterpenes","display_name":"labdane diterpenes","score":0.996999979019165},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.6859999895095825},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.890999972820282},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8510000109672546},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.996999979019165},{"id":"https://openalex.org/keywords/il-12p40","display_name":"IL-12p40","score":0.953000009059906},{"id":"https://openalex.org/keywords/dendritic-cells","display_name":"dendritic cells","score":0.8270000219345093},{"id":"https://openalex.org/keywords/lipopolysaccharide","display_name":"lipopolysaccharide","score":0.8619999885559082},{"id":"https://openalex.org/keywords/traditional-medicine","display_name":"traditional medicine","score":0.5600000023841858},{"id":"https://openalex.org/keywords/structure-elucidation","display_name":"structure elucidation","score":0.7900000214576721}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8026679158210754},{"id":"https://openalex.org/C134550120","wikidata":"https://www.wikidata.org/wiki/Q184208","display_name":"Rhizome","level":2,"score":0.6654349565505981},{"id":"https://openalex.org/C2778594897","wikidata":"https://www.wikidata.org/wiki/Q8214660","display_name":"Labdane","level":3,"score":0.5856300592422485},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5613085031509399},{"id":"https://openalex.org/C2778754761","wikidata":"https://www.wikidata.org/wiki/Q421804","display_name":"Lipopolysaccharide","level":2,"score":0.4794822633266449},{"id":"https://openalex.org/C164027704","wikidata":"https://www.wikidata.org/wiki/Q3491837","display_name":"Proinflammatory cytokine","level":3,"score":0.4511718153953552},{"id":"https://openalex.org/C2776789170","wikidata":"https://www.wikidata.org/wiki/Q37021","display_name":"Zingiberaceae","level":3,"score":0.4322768449783325},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.42246904969215393},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.39132189750671387},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.3818415701389313},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.36218369007110596},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22541877627372742},{"id":"https://openalex.org/C2776710815","wikidata":"https://www.wikidata.org/wiki/Q59447","display_name":"Diterpene","level":2,"score":0.20581039786338806},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1326030194759369}],"mesh":[{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000893","descriptor_name":"Anti-Inflammatory Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001854","descriptor_name":"Bone Marrow Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008070","descriptor_name":"Lipopolysaccharides","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D014409","descriptor_name":"Tumor Necrosis Factor-alpha","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015850","descriptor_name":"Interleukin-6","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018664","descriptor_name":"Interleukin-12","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D027343","descriptor_name":"Rhizome","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D030521","descriptor_name":"Zingiberaceae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bmcl.2011.09.129","doi":"https://doi.org/10.1016/j.bmcl.2011.09.129","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bmcl.2011.09.129","pdf_url":null,"source":{"id":"https://openalex.org/S30970080","display_name":"Bioorganic & Medicinal Chemistry Letters","issn_l":"0960-894X","issn":["0960-894X","1464-3405"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & Medicinal Chemistry Letters","raw_type":"journal-article"},{"id":"pmid:22071304","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22071304","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioorganic & medicinal chemistry letters","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320322349","display_name":"Ministry of Education, Science and Technology","ror":"https://ror.org/01p262204"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W75266634","https://openalex.org/W1932687143","https://openalex.org/W1968918322","https://openalex.org/W1974751146","https://openalex.org/W1975821368","https://openalex.org/W1991524518","https://openalex.org/W2002209097","https://openalex.org/W2002228847","https://openalex.org/W2004465286","https://openalex.org/W2014084973","https://openalex.org/W2030815264","https://openalex.org/W2036915476","https://openalex.org/W2037280064","https://openalex.org/W2046310274","https://openalex.org/W2068335413","https://openalex.org/W2075840738","https://openalex.org/W2095269663","https://openalex.org/W2098586771","https://openalex.org/W2113010954","https://openalex.org/W2130933356","https://openalex.org/W2131727319","https://openalex.org/W2166186961"],"related_works":["https://openalex.org/W2072231482","https://openalex.org/W2953210378","https://openalex.org/W2950725349","https://openalex.org/W2326837583","https://openalex.org/W1972616002","https://openalex.org/W7098099795","https://openalex.org/W2952099711","https://openalex.org/W1597717096","https://openalex.org/W2049312570","https://openalex.org/W1974751146"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}