{"id":"https://openalex.org/W2149407902","doi":"https://doi.org/10.1093/jac/dki193","title":"The antibacterial activity of honey against coagulase-negative staphylococci","display_name":"The antibacterial activity of honey against coagulase-negative staphylococci","publication_year":2005,"publication_date":"2005-06-07","ids":{"openalex":"https://openalex.org/W2149407902","doi":"https://doi.org/10.1093/jac/dki193","mag":"2149407902","pmid":"https://pubmed.ncbi.nlm.nih.gov/15941774"},"language":"en","primary_location":{"id":"doi:10.1093/jac/dki193","doi":"https://doi.org/10.1093/jac/dki193","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/dki193","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hdl.handle.net/10289/2144","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024873444","display_name":"V. M. French","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52179390","display_name":"University of Waikato","ror":"https://ror.org/013fsnh78","country_code":"NZ","type":"education","lineage":["https://openalex.org/I52179390"]}],"countries":["NZ"],"is_corresponding":true,"raw_author_name":"V. M. French","raw_affiliation_strings":["Honey Research Unit, Department of Biological Sciences University of Waikato, Hamilton, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Honey Research Unit, Department of Biological Sciences University of Waikato, Hamilton, New Zealand","institution_ids":["https://openalex.org/I52179390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113537818","display_name":"R.A. Cooper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I8408910","display_name":"Cardiff Metropolitan University","ror":"https://ror.org/00bqvf857","country_code":"GB","type":"education","lineage":["https://openalex.org/I8408910"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"R. A. Cooper","raw_affiliation_strings":["Centre for Biomedical Sciences, School of Applied Sciences, University of Wales Institute, Cardiff, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Biomedical Sciences, School of Applied Sciences, University of Wales Institute, Cardiff, U.K","institution_ids":["https://openalex.org/I8408910"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110034436","display_name":"P. C. Molan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52179390","display_name":"University of Waikato","ror":"https://ror.org/013fsnh78","country_code":"NZ","type":"education","lineage":["https://openalex.org/I52179390"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"P. C. Molan","raw_affiliation_strings":["Honey Research Unit, Department of Biological Sciences University of Waikato, Hamilton, New Zealand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Honey Research Unit, Department of Biological Sciences University of Waikato, Hamilton, New Zealand","institution_ids":["https://openalex.org/I52179390"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5024873444"],"corresponding_institution_ids":["https://openalex.org/I52179390"],"apc_list":{"value":2869,"currency":"GBP","value_usd":3784},"apc_paid":null,"fwci":10.3851,"has_fulltext":true,"cited_by_count":232,"citation_normalized_percentile":{"value":0.98947632,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"56","issue":"1","first_page":"228","last_page":"231"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11386","display_name":"Bee Products Chemical Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11386","display_name":"Bee Products Chemical Analysis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/honey","display_name":"honey","score":0.972000002861023},{"id":"https://openalex.org/keywords/coagulase-negative-staphylococci","display_name":"coagulase-negative staphylococci","score":0.9470000267028809},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9330000281333923},{"id":"https://openalex.org/keywords/minimum-inhibitory-concentration","display_name":"minimum inhibitory concentration","score":0.8240000009536743},{"id":"https://openalex.org/keywords/manuka-honey","display_name":"manuka honey","score":0.9409999847412109},{"id":"https://openalex.org/keywords/sugar-syrup","display_name":"sugar syrup","score":0.6610000133514404},{"id":"https://openalex.org/keywords/osmotic-effects","display_name":"osmotic effects","score":0.8629999756813049},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"antibiotic resistance","score":0.7300000190734863},{"id":"https://openalex.org/keywords/medical-device-related-infections","display_name":"medical device-related infections","score":0.7860000133514404},{"id":"https://openalex.org/keywords/wound-infection-treatment","display_name":"wound infection treatment","score":0.5139999985694885},{"id":"https://openalex.org/keywords/infection-control","display_name":"infection control","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C8408860","wikidata":"https://www.wikidata.org/wiki/Q1755077","display_name":"Coagulase","level":5,"score":0.7781420946121216},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6564464569091797},{"id":"https://openalex.org/C2779288629","wikidata":"https://www.wikidata.org/wiki/Q199695","display_name":"Staphylococcus","level":4,"score":0.4547097980976105},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.4544234573841095},{"id":"https://openalex.org/C3019249092","wikidata":"https://www.wikidata.org/wiki/Q274493","display_name":"Antibacterial agent","level":3,"score":0.4311544597148895},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3736923336982727},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34378954768180847},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.3066115975379944},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.30585139989852905},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.23225164413452148},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003030","descriptor_name":"Coagulase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006722","descriptor_name":"Honey","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009994","descriptor_name":"Osmolar Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013210","descriptor_name":"Staphylococcus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013210","descriptor_name":"Staphylococcus","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1093/jac/dki193","doi":"https://doi.org/10.1093/jac/dki193","is_oa":false,"landing_page_url":"https://doi.org/10.1093/jac/dki193","pdf_url":null,"source":{"id":"https://openalex.org/S124275759","display_name":"Journal of Antimicrobial Chemotherapy","issn_l":"0305-7453","issn":["0305-7453","1460-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Antimicrobial Chemotherapy","raw_type":"journal-article"},{"id":"pmid:15941774","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15941774","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of antimicrobial chemotherapy","raw_type":"Journal Article"},{"id":"pmh:oai:researchcommons.waikato.ac.nz:10289/2144","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10289/2144","pdf_url":"https://hdl.handle.net/10289/2144","source":{"id":"https://openalex.org/S4306400944","display_name":"Research Commons (University of Waikato)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I52179390","host_organization_name":"University of Waikato","host_organization_lineage":["https://openalex.org/I52179390"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:jac:dki193v1","doi":null,"is_oa":false,"landing_page_url":"http://jac.oxfordjournals.org/cgi/content/short/dki193v1","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:repository.cardiffmet.ac.uk:10369/316","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10369/316","pdf_url":null,"source":{"id":"https://openalex.org/S4306401326","display_name":"Cardiff Metropolitan Research Repository (Cardiff Metropolitan University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I8408910","host_organization_name":"Cardiff Metropolitan University","host_organization_lineage":["https://openalex.org/I8408910"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null}],"best_oa_location":{"id":"pmh:oai:researchcommons.waikato.ac.nz:10289/2144","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/10289/2144","pdf_url":"https://hdl.handle.net/10289/2144","source":{"id":"https://openalex.org/S4306400944","display_name":"Research Commons (University of Waikato)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I52179390","host_organization_name":"University of Waikato","host_organization_lineage":["https://openalex.org/I52179390"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"},{"id":"https://metadata.un.org/sdg/2","score":0.4359000027179718,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320793","display_name":"Waikato Medical Research Foundation","ror":"https://ror.org/001xe7y71"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2149407902.pdf","grobid_xml":"https://content.openalex.org/works/W2149407902.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1838399447","https://openalex.org/W1850712295","https://openalex.org/W1951312396","https://openalex.org/W1979660821","https://openalex.org/W2058596576","https://openalex.org/W2076400854","https://openalex.org/W2098845383","https://openalex.org/W2128975976","https://openalex.org/W2146664815","https://openalex.org/W2317832954","https://openalex.org/W2327152574","https://openalex.org/W2328339276"],"related_works":["https://openalex.org/W2944017925","https://openalex.org/W1951312396","https://openalex.org/W2146664815","https://openalex.org/W175011898","https://openalex.org/W2182377442","https://openalex.org/W4248049307","https://openalex.org/W2992730748","https://openalex.org/W3094929924","https://openalex.org/W2174829007","https://openalex.org/W3112975685"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Development":[1],"of":[2,5,12,18,51,61,70,89,95,98,106,116,118,186,198],"antibiotic-resistant":[3],"strains":[4],"coagulase-negative":[6,47,71,165,201],"staphylococci":[7,166],"has":[8],"complicated":[9],"the":[10,16,57,82,103,119,135,143,152,183,194],"management":[11],"infections":[13,199],"associated":[14],"with":[15,86,112],"use":[17],"invasive":[19],"medical":[20,187],"devices,":[21],"and":[22,25,146],"innovative":[23],"treatment":[24,195],"prophylactic":[26],"options":[27],"are":[28,158],"needed.":[29],"Honey":[30],"is":[31,41],"increasingly":[32],"being":[33],"used":[34,79],"to":[35,55,80,129,173,180],"treat":[36],"infected":[37],"wounds,":[38],"but":[39],"little":[40],"known":[42],"about":[43,159],"its":[44],"effectiveness":[45],"against":[46,164],"staphylococci.":[48,72,202],"The":[49,108,122],"aim":[50],"this":[52],"study":[53],"was":[54,78],"determine":[56,81],"minimum":[58,83],"active":[59,84],"dilution":[60,87],"two":[62],"standardized,":[63],"representative":[64],"honeys":[65,123,157],"for":[66,134,142,151],"18":[67],"clinical":[68],"isolates":[69],"METHODS:":[73],"An":[74],"agar":[75],"incorporation":[76],"technique":[77],"dilution,":[85],"steps":[88,94],"1%":[90],"(v/v)":[91,97,133,141,150],"honey":[92,145,178],"[or":[93],"5%":[96],"a":[99,191],"sugar":[100,153],"syrup":[101],"matching":[102],"osmotic":[104],"effect":[105],"honey].":[107],"plates":[109],"were":[110,124,171],"inoculated":[111],"10":[113],"microL":[114],"spots":[115],"cultures":[117],"isolates.":[120],"RESULTS:":[121],"inhibitory":[125],"at":[126,182],"dilutions":[127],"down":[128],"3.6":[130],"+/-":[131,139,148],"0.7%":[132],"pasture":[136],"honey,":[137],"3.4":[138],"0.5%":[140],"manuka":[144],"29.9":[147],"1.9%":[149],"syrup.":[154],"CONCLUSIONS:":[155],"Typical":[156],"eight":[160],"times":[161],"more":[162],"potent":[163],"than":[167],"if":[168],"bacterial":[169],"inhibition":[170],"due":[172],"their":[174],"osmolarity":[175],"alone.":[176],"Therefore,":[177],"applied":[179],"skin":[181],"insertion":[184],"points":[185],"devices":[188],"may":[189],"have":[190],"role":[192],"in":[193],"or":[196],"prevention":[197],"by":[200]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":17},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":14},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}