{"id":"https://openalex.org/W2149402224","doi":null,"title":"VEGF Levels in Women with Gynaecological Cancers","display_name":"VEGF Levels in Women with Gynaecological Cancers","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2149402224","mag":"2149402224"},"language":"en","primary_location":{"id":"pmh:oai:alma.64OTAGO_INST:11396539470001891","doi":null,"is_oa":true,"landing_page_url":"https://ourarchive.otago.ac.nz/esploro/outputs/graduate/VEGF-Levels-in-Women-with-Gynaecological/9926478771201891","pdf_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396539460001891/13397097640001891","source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Masters Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396539460001891/13397097640001891","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077931676","display_name":"Jeffrey Lee","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jeffrey Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5077931676"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.9729999899864197},{"id":"https://openalex.org/keywords/gynecologic-cancer","display_name":"gynecologic cancer","score":0.8500000238418579},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.9850000143051147},{"id":"https://openalex.org/keywords/endometrial-cancer","display_name":"endometrial cancer","score":1.0},{"id":"https://openalex.org/keywords/serum-vegf","display_name":"serum VEGF","score":0.8149999976158142},{"id":"https://openalex.org/keywords/plasma-vegf-levels","display_name":"plasma VEGF levels","score":1.0},{"id":"https://openalex.org/keywords/platelets","display_name":"platelets","score":0.6970000267028809},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9950000047683716},{"id":"https://openalex.org/keywords/green-tea","display_name":"green tea","score":0.7889999747276306},{"id":"https://openalex.org/keywords/epigallocatechin-gallate","display_name":"epigallocatechin gallate","score":0.824999988079071},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7900000214576721},{"id":"https://openalex.org/keywords/tumor-markers","display_name":"tumor markers","score":0.6859999895095825},{"id":"https://openalex.org/keywords/tumor-burden","display_name":"tumor burden","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C167734588","wikidata":"https://www.wikidata.org/wiki/Q4356503","display_name":"VEGF receptors","level":2,"score":0.5614851117134094},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.527525007724762},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.42686909437179565},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4112381041049957},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4019739031791687},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.357298344373703}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:alma.64OTAGO_INST:11396539470001891","doi":null,"is_oa":true,"landing_page_url":"https://ourarchive.otago.ac.nz/esploro/outputs/graduate/VEGF-Levels-in-Women-with-Gynaecological/9926478771201891","pdf_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396539460001891/13397097640001891","source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Masters Thesis"},{"id":"pmh:oai:ourarchive.otago.ac.nz:10523/2283","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10523/2283","pdf_url":null,"source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis or Dissertation"},{"id":"mag:2149402224","doi":null,"is_oa":false,"landing_page_url":"https://ourarchive.otago.ac.nz/bitstream/10523/2283/2/LeeJeffrey2012BMedSc.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:alma.64OTAGO_INST:11396539470001891","doi":null,"is_oa":true,"landing_page_url":"https://ourarchive.otago.ac.nz/esploro/outputs/graduate/VEGF-Levels-in-Women-with-Gynaecological/9926478771201891","pdf_url":"https://ourarchive.otago.ac.nz/view/delivery/64OTAGO_INST/12396539460001891/13397097640001891","source":{"id":"https://openalex.org/S4306402094","display_name":"Otago University Research Archive (University of Otago)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I80281795","host_organization_name":"University of Otago","host_organization_lineage":["https://openalex.org/I80281795"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Masters Thesis"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2149402224.pdf","grobid_xml":"https://content.openalex.org/works/W2149402224.grobid-xml"},"referenced_works_count":136,"referenced_works":["https://openalex.org/W32167704","https://openalex.org/W41582646","https://openalex.org/W56370111","https://openalex.org/W81844647","https://openalex.org/W119198626","https://openalex.org/W327131631","https://openalex.org/W1484771785","https://openalex.org/W1585437324","https://openalex.org/W1625791533","https://openalex.org/W1889954278","https://openalex.org/W1896985636","https://openalex.org/W1918337600","https://openalex.org/W1967314100","https://openalex.org/W1967606317","https://openalex.org/W1969249647","https://openalex.org/W1978139448","https://openalex.org/W1979985676","https://openalex.org/W1980102481","https://openalex.org/W1980126101","https://openalex.org/W1982246723","https://openalex.org/W1989646379","https://openalex.org/W1995637683","https://openalex.org/W1997116070","https://openalex.org/W1998258610","https://openalex.org/W1999223106","https://openalex.org/W1999797961","https://openalex.org/W2000292756","https://openalex.org/W2000519650","https://openalex.org/W2001282311","https://openalex.org/W2002382373","https://openalex.org/W2003153226","https://openalex.org/W2003656890","https://openalex.org/W2010300658","https://openalex.org/W2012139240","https://openalex.org/W2012164798","https://openalex.org/W2013335354","https://openalex.org/W2015143684","https://openalex.org/W2015795623","https://openalex.org/W2017616890","https://openalex.org/W2019515506","https://openalex.org/W2021032647","https://openalex.org/W2021547142","https://openalex.org/W2021580116","https://openalex.org/W2021829324","https://openalex.org/W2024346001","https://openalex.org/W2026040027","https://openalex.org/W2028946225","https://openalex.org/W2032941828","https://openalex.org/W2034301104","https://openalex.org/W2036013092","https://openalex.org/W2036093957","https://openalex.org/W2038126486","https://openalex.org/W2038475449","https://openalex.org/W2039381387","https://openalex.org/W2045652910","https://openalex.org/W2049641944","https://openalex.org/W2050325895","https://openalex.org/W2051275595","https://openalex.org/W2052024663","https://openalex.org/W2054320379","https://openalex.org/W2055497824","https://openalex.org/W2056876101","https://openalex.org/W2062948597","https://openalex.org/W2067266295","https://openalex.org/W2067705652","https://openalex.org/W2069179543","https://openalex.org/W2075181119","https://openalex.org/W2078075549","https://openalex.org/W2078896895","https://openalex.org/W2080770264","https://openalex.org/W2088561077","https://openalex.org/W2088601600","https://openalex.org/W2088605481","https://openalex.org/W2091828677","https://openalex.org/W2094433686","https://openalex.org/W2094969826","https://openalex.org/W2095462135","https://openalex.org/W2095839230","https://openalex.org/W2096036261","https://openalex.org/W2101685363","https://openalex.org/W2103498170","https://openalex.org/W2105408725","https://openalex.org/W2105669982","https://openalex.org/W2106787323","https://openalex.org/W2108310638","https://openalex.org/W2108392416","https://openalex.org/W2112220469","https://openalex.org/W2113069354","https://openalex.org/W2113602269","https://openalex.org/W2114234907","https://openalex.org/W2116207286","https://openalex.org/W2116993043","https://openalex.org/W2118689279","https://openalex.org/W2120264116","https://openalex.org/W2120863072","https://openalex.org/W2121305414","https://openalex.org/W2121829724","https://openalex.org/W2128098778","https://openalex.org/W2129246117","https://openalex.org/W2132493672","https://openalex.org/W2134648032","https://openalex.org/W2136344183","https://openalex.org/W2139201942","https://openalex.org/W2139321297","https://openalex.org/W2140503760","https://openalex.org/W2140596633","https://openalex.org/W2141145436","https://openalex.org/W2141680653","https://openalex.org/W2141809725","https://openalex.org/W2143437663","https://openalex.org/W2145159715","https://openalex.org/W2147409958","https://openalex.org/W2152657512","https://openalex.org/W2152835156","https://openalex.org/W2154621970","https://openalex.org/W2157769714","https://openalex.org/W2158743409","https://openalex.org/W2158965678","https://openalex.org/W2161688555","https://openalex.org/W2161808292","https://openalex.org/W2166260885","https://openalex.org/W2166573361","https://openalex.org/W2166618443","https://openalex.org/W2166893909","https://openalex.org/W2169186139","https://openalex.org/W2169685423","https://openalex.org/W2170714849","https://openalex.org/W2189178782","https://openalex.org/W2324677651","https://openalex.org/W2366827928","https://openalex.org/W2411496192","https://openalex.org/W2412169570","https://openalex.org/W2417878835","https://openalex.org/W2431827525","https://openalex.org/W2588519295","https://openalex.org/W2620820926"],"related_works":["https://openalex.org/W2062948597","https://openalex.org/W1979985676","https://openalex.org/W2026975152","https://openalex.org/W2115510606","https://openalex.org/W2090267534","https://openalex.org/W2381500563","https://openalex.org/W4416184361","https://openalex.org/W2161808292","https://openalex.org/W2095839230","https://openalex.org/W2128098778"],"abstract_inverted_index":{"Background:":[0],"High":[1],"blood":[2,104,161,264,285,368],"levels":[3,308,313],"of":[4,61,94,156,172,198,209,306,322,342,372,392],"Vascular":[5],"Endothelial":[6],"Growth":[7],"Factor":[8],"(VEGF)":[9],"have":[10,19],"been":[11,20],"reported":[12],"in":[13,66,113,117,126,134,143,182,226,284,293,309,324,367],"patients":[14,311],"with":[15,22,68,77,83,119,128,184,190,231,241,296,333],"gynaecological":[16,120,298],"cancer":[17,186],"and":[18,25,32,34,57,63,70,79,115,133,146,158,177,217,233,243,245,255,267,336,338,389],"correlated":[21,240],"advanced":[23,297,347],"disease":[24,84,232],"poor":[26],"outcome.":[27],"However,":[28],"results":[29],"are":[30,291,377],"few":[31],"varied":[33,332],"most":[35],"studies":[36,376],"used":[37],"single":[38,300],"measurements.":[39],"There":[40,222,258],"is":[41,350],"also":[42,141],"debate":[43],"as":[44],"to":[45,90,160,206,248,281,317,346,353,379,381],"whether":[46],"serum":[47,62,114,176,216,256],"or":[48,130,151],"plasma":[49,64,116,178,220,239,254,356,384],"measurement":[50],"reflects":[51,358],"circulating":[52,359,387],"VEGF.":[53,105,221,257,286,360],"Aims:":[54],"To":[55,73],"describe":[56],"compare":[58],"the":[59,92,170,307,343,390],"properties":[60],"VEGF":[65,107,162,179,227,236,265,289,331,357,369,385],"women":[67,118,127,135,144,183,230,295],"ovarian":[69,131,152],"endometrial":[71,129,150],"cancer.":[72,137,153],"clarify":[74],"their":[75,81],"relationships":[76],"platelets":[78,157,242],"investigate":[80,91],"correlation":[82],"activity.":[85],"In":[86,168],"addition":[87],"we":[88],"wished":[89],"effect":[93,171,391],"green":[95,173,194,272,373,393],"tea":[96,174,195,273,394],"(which":[97],"has":[98],"known":[99],"angiogenic":[100],"activities)":[101],"consumption":[102,371],"on":[103,175],"Methods:":[106],"was":[108,163,180,212,223,259],"measured":[109],"by":[110],"ELISA":[111],"method":[112],"cancers.":[121],"Serial":[122],"measurements":[123,290,301],"were":[124,140,188,275],"taken":[125],"cancer,":[132],"without":[136],"Blood":[138,288],"samples":[139],"obtained":[142],"before":[145,266],"after":[147,268,370],"surgery":[148],"for":[149,215,219],"The":[154,203],"association":[155],"CRP":[159,244,337],"determined":[164],"using":[165],"combined":[166],"data.":[167],"addition,":[169],"evaluated":[181],"persistent":[185],"who":[187],"treated":[189],"6":[191],"days":[192],"oral":[193],"extracts":[196,274],"equivalent":[197],"900mg":[199],"EGCG":[200],"daily.":[201],"Results:":[202],"median":[204],"week":[205,207],"coefficient":[208],"variance":[210],"(CV)":[211],"approximately":[213],"10%":[214],"30%":[218],"significant":[224,261,282],"overlap":[225],"concentrations":[228],"between":[229,253,263],"control.":[234],"Serum":[235,330],"but":[237,277,312],"not":[238,279,315,351,363],"there":[246],"appeared":[247],"be":[249,318,340],"a":[250,303,319,365],"multiplicative":[251],"relationship":[252],"no":[260],"difference":[262],"surgery.":[269],"Short":[270],"term":[271],"safe":[276],"did":[278,314,362],"lead":[280],"changes":[283],"Conclusion:":[287],"elevated":[292],"some":[294],"cancers,":[299],"appear":[302,316],"reliable":[304],"indication":[305],"different":[310],"good":[320],"indicator":[321],"change":[323],"tumour":[325],"load":[326],"within":[327],"individual":[328],"patients.":[329],"platelet":[334],"count":[335],"may":[339],"reflection":[341],"systemic":[344],"response":[345],"malignancy.":[348],"It":[349],"clear":[352],"what":[354,382],"extent":[355,383],"We":[361],"see":[364],"reduction":[366],"tea.":[374],"Future":[375],"needed":[378],"assess":[380],"reflect":[386],"VEGF,":[388],"extracts.":[395]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}