{"id":"https://openalex.org/W2149286152","doi":"https://doi.org/10.1146/annurev.arplant.56.032604.144246","title":"REDOX REGULATION: A Broadening Horizon","display_name":"REDOX REGULATION: A Broadening Horizon","publication_year":2005,"publication_date":"2005-01-27","ids":{"openalex":"https://openalex.org/W2149286152","doi":"https://doi.org/10.1146/annurev.arplant.56.032604.144246","mag":"2149286152","pmid":"https://pubmed.ncbi.nlm.nih.gov/15862094"},"language":"en","primary_location":{"id":"doi:10.1146/annurev.arplant.56.032604.144246","doi":"https://doi.org/10.1146/annurev.arplant.56.032604.144246","is_oa":false,"landing_page_url":"https://doi.org/10.1146/annurev.arplant.56.032604.144246","pdf_url":null,"source":{"id":"https://openalex.org/S176558078","display_name":"Annual Review of Plant Biology","issn_l":"1543-5008","issn":["1543-5008","1545-2123"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320373","host_organization_name":"Annual Reviews","host_organization_lineage":["https://openalex.org/P4310320373"],"host_organization_lineage_names":["Annual Reviews"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual Review of Plant Biology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2149286152"],"child_works_count":0,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109939685","display_name":"Bob B. Buchanan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bob B. Buchanan","raw_affiliation_strings":["Department of Plant and Microbial Biology, University of California, Berkeley, California 94720;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant and Microbial Biology, University of California, Berkeley, California 94720;","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051515090","display_name":"Yves Balmer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yves Balmer","raw_affiliation_strings":["Department of Plant and Microbial Biology, University of California, Berkeley, California 94720;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Plant and Microbial Biology, University of California, Berkeley, California 94720;","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":null,"apc_paid":null,"fwci":5.0701,"has_fulltext":false,"cited_by_count":900,"citation_normalized_percentile":{"value":0.98067166,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"56","issue":"1","first_page":"187","last_page":"220"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10014","display_name":"Plant Stress Responses and Tolerance","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/redox-regulation","display_name":"redox regulation","score":0.9670000076293945},{"id":"https://openalex.org/keywords/thiol-disulfide-exchange","display_name":"thiol-disulfide exchange","score":0.9330000281333923},{"id":"https://openalex.org/keywords/ferredoxin-thioredoxin-system","display_name":"ferredoxin-thioredoxin system","score":0.8240000009536743},{"id":"https://openalex.org/keywords/thioredoxin","display_name":"thioredoxin","score":0.8140000104904175},{"id":"https://openalex.org/keywords/ferredoxin-thioredoxin-reductase","display_name":"ferredoxin-thioredoxin reductase","score":0.9580000042915344},{"id":"https://openalex.org/keywords/nadph","display_name":"NADPH","score":0.6990000009536743},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.7570000290870667},{"id":"https://openalex.org/keywords/glutaredoxin","display_name":"glutaredoxin","score":0.9959999918937683},{"id":"https://openalex.org/keywords/protein-disulfide-isomerase","display_name":"protein disulfide isomerase","score":0.9950000047683716},{"id":"https://openalex.org/keywords/plastoquinone","display_name":"plastoquinone","score":0.8489999771118164},{"id":"https://openalex.org/keywords/reactive-oxygen-species-signaling","display_name":"reactive oxygen species signaling","score":0.9369999766349792},{"id":"https://openalex.org/keywords/photosynthesis","display_name":"photosynthesis","score":0.5759999752044678},{"id":"https://openalex.org/keywords/protein-regulation","display_name":"protein regulation","score":0.38199999928474426}],"concepts":[{"id":"https://openalex.org/C3623737","wikidata":"https://www.wikidata.org/wiki/Q421219","display_name":"Thioredoxin","level":3,"score":0.9534030556678772},{"id":"https://openalex.org/C125619963","wikidata":"https://www.wikidata.org/wiki/Q81984039","display_name":"Glutaredoxin","level":4,"score":0.9329195022583008},{"id":"https://openalex.org/C70412867","wikidata":"https://www.wikidata.org/wiki/Q5445278","display_name":"Ferredoxin-thioredoxin reductase","level":5,"score":0.7865482568740845},{"id":"https://openalex.org/C2777737464","wikidata":"https://www.wikidata.org/wiki/Q2540636","display_name":"Thioredoxin reductase","level":4,"score":0.7738159894943237},{"id":"https://openalex.org/C134621786","wikidata":"https://www.wikidata.org/wiki/Q415215","display_name":"Ferredoxin","level":3,"score":0.7367644309997559},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.607390284538269},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.5987876653671265},{"id":"https://openalex.org/C5098756","wikidata":"https://www.wikidata.org/wiki/Q1641611","display_name":"Protein disulfide-isomerase","level":3,"score":0.5766180753707886},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5040651559829712},{"id":"https://openalex.org/C55904794","wikidata":"https://www.wikidata.org/wiki/Q82682","display_name":"Redox","level":2,"score":0.5034148097038269},{"id":"https://openalex.org/C2780416994","wikidata":"https://www.wikidata.org/wiki/Q419462","display_name":"Peroxiredoxin","level":4,"score":0.5006899833679199},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4461207091808319},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37752994894981384},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34729325771331787},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2953251898288727},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C162008176","wikidata":"https://www.wikidata.org/wiki/Q419305","display_name":"Peroxidase","level":3,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003624","descriptor_name":"Darkness","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006868","descriptor_name":"Hydrolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009249","descriptor_name":"NADP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D013879","descriptor_name":"Thioredoxins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018521","descriptor_name":"Plant Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045331","descriptor_name":"Photosystem I Protein Complex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D045332","descriptor_name":"Photosystem II Protein Complex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D054477","descriptor_name":"Glutaredoxins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1146/annurev.arplant.56.032604.144246","doi":"https://doi.org/10.1146/annurev.arplant.56.032604.144246","is_oa":false,"landing_page_url":"https://doi.org/10.1146/annurev.arplant.56.032604.144246","pdf_url":null,"source":{"id":"https://openalex.org/S176558078","display_name":"Annual Review of Plant Biology","issn_l":"1543-5008","issn":["1543-5008","1545-2123"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320373","host_organization_name":"Annual Reviews","host_organization_lineage":["https://openalex.org/P4310320373"],"host_organization_lineage_names":["Annual Reviews"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual Review of Plant Biology","raw_type":"journal-article"},{"id":"pmid:15862094","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15862094","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annual review of plant biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":214,"referenced_works":["https://openalex.org/W10328790","https://openalex.org/W68544838","https://openalex.org/W261113894","https://openalex.org/W1257563052","https://openalex.org/W1513279869","https://openalex.org/W1514121733","https://openalex.org/W1537187877","https://openalex.org/W1556517310","https://openalex.org/W1559045096","https://openalex.org/W1647986506","https://openalex.org/W1707357231","https://openalex.org/W1761070129","https://openalex.org/W1786911182","https://openalex.org/W1835058763","https://openalex.org/W1924154635","https://openalex.org/W1965416085","https://openalex.org/W1967044914","https://openalex.org/W1967253478","https://openalex.org/W1967650766","https://openalex.org/W1970875356","https://openalex.org/W1971798720","https://openalex.org/W1972606544","https://openalex.org/W1973352575","https://openalex.org/W1973592859","https://openalex.org/W1974030802","https://openalex.org/W1975195884","https://openalex.org/W1976240560","https://openalex.org/W1978473107","https://openalex.org/W1981557478","https://openalex.org/W1981964097","https://openalex.org/W1982167087","https://openalex.org/W1982653932","https://openalex.org/W1982850624","https://openalex.org/W1983414952","https://openalex.org/W1983470427","https://openalex.org/W1984294720","https://openalex.org/W1985100115","https://openalex.org/W1986160345","https://openalex.org/W1987126692","https://openalex.org/W1987367615","https://openalex.org/W1988815574","https://openalex.org/W1988924778","https://openalex.org/W1989005258","https://openalex.org/W1991249016","https://openalex.org/W1991905208","https://openalex.org/W1992162879","https://openalex.org/W1994776145","https://openalex.org/W1995310701","https://openalex.org/W1995888196","https://openalex.org/W1996606591","https://openalex.org/W1997147112","https://openalex.org/W1998235300","https://openalex.org/W1998591953","https://openalex.org/W1999221113","https://openalex.org/W1999936984","https://openalex.org/W2000489478","https://openalex.org/W2000704841","https://openalex.org/W2002040395","https://openalex.org/W2002587784","https://openalex.org/W2006688297","https://openalex.org/W2008049094","https://openalex.org/W2010159203","https://openalex.org/W2012106492","https://openalex.org/W2013281807","https://openalex.org/W2014282903","https://openalex.org/W2014336412","https://openalex.org/W2014340225","https://openalex.org/W2014703942","https://openalex.org/W2014962124","https://openalex.org/W2014981936","https://openalex.org/W2015980107","https://openalex.org/W2016620136","https://openalex.org/W2016634464","https://openalex.org/W2018335923","https://openalex.org/W2019803421","https://openalex.org/W2020585015","https://openalex.org/W2021052050","https://openalex.org/W2021289354","https://openalex.org/W2021451290","https://openalex.org/W2021791554","https://openalex.org/W2023046517","https://openalex.org/W2024829139","https://openalex.org/W2025641351","https://openalex.org/W2026368793","https://openalex.org/W2027305766","https://openalex.org/W2027440363","https://openalex.org/W2028519557","https://openalex.org/W2029799567","https://openalex.org/W2032246749","https://openalex.org/W2033712553","https://openalex.org/W2036170837","https://openalex.org/W2036181141","https://openalex.org/W2036289649","https://openalex.org/W2036411394","https://openalex.org/W2037212449","https://openalex.org/W2038337940","https://openalex.org/W2038412942","https://openalex.org/W2039643915","https://openalex.org/W2040153210","https://openalex.org/W2040829829","https://openalex.org/W2041671226","https://openalex.org/W2043512651","https://openalex.org/W2044604749","https://openalex.org/W2044726248","https://openalex.org/W2045621445","https://openalex.org/W2047170573","https://openalex.org/W2047841749","https://openalex.org/W2049892150","https://openalex.org/W2052299129","https://openalex.org/W2052904242","https://openalex.org/W2054262102","https://openalex.org/W2055917361","https://openalex.org/W2057324469","https://openalex.org/W2057683495","https://openalex.org/W2058231188","https://openalex.org/W2062015456","https://openalex.org/W2062263277","https://openalex.org/W2062336656","https://openalex.org/W2063205422","https://openalex.org/W2064488173","https://openalex.org/W2064899851","https://openalex.org/W2065275854","https://openalex.org/W2065744271","https://openalex.org/W2066224879","https://openalex.org/W2066800640","https://openalex.org/W2067303294","https://openalex.org/W2070038134","https://openalex.org/W2070367554","https://openalex.org/W2072264095","https://openalex.org/W2074012979","https://openalex.org/W2074425133","https://openalex.org/W2074502898","https://openalex.org/W2074878376","https://openalex.org/W2075123870","https://openalex.org/W2075320938","https://openalex.org/W2076059990","https://openalex.org/W2076575552","https://openalex.org/W2078174502","https://openalex.org/W2080579227","https://openalex.org/W2080682062","https://openalex.org/W2081359254","https://openalex.org/W2081886586","https://openalex.org/W2083253012","https://openalex.org/W2084015464","https://openalex.org/W2085371907","https://openalex.org/W2085522310","https://openalex.org/W2087425091","https://openalex.org/W2087975443","https://openalex.org/W2088256976","https://openalex.org/W2090703659","https://openalex.org/W2091870229","https://openalex.org/W2098620021","https://openalex.org/W2102525426","https://openalex.org/W2102607114","https://openalex.org/W2103650142","https://openalex.org/W2108461880","https://openalex.org/W2109648850","https://openalex.org/W2110550759","https://openalex.org/W2115771825","https://openalex.org/W2115788921","https://openalex.org/W2115866117","https://openalex.org/W2118121572","https://openalex.org/W2118940991","https://openalex.org/W2121418961","https://openalex.org/W2121792167","https://openalex.org/W2122639303","https://openalex.org/W2123052642","https://openalex.org/W2123808383","https://openalex.org/W2124823719","https://openalex.org/W2127232356","https://openalex.org/W2127309730","https://openalex.org/W2127699503","https://openalex.org/W2128858281","https://openalex.org/W2130778658","https://openalex.org/W2130956052","https://openalex.org/W2131026700","https://openalex.org/W2131332009","https://openalex.org/W2131987851","https://openalex.org/W2135773311","https://openalex.org/W2140079497","https://openalex.org/W2141802124","https://openalex.org/W2142698947","https://openalex.org/W2142709713","https://openalex.org/W2144705115","https://openalex.org/W2145013322","https://openalex.org/W2145419814","https://openalex.org/W2149585271","https://openalex.org/W2152144929","https://openalex.org/W2154140763","https://openalex.org/W2157808602","https://openalex.org/W2158601486","https://openalex.org/W2160437934","https://openalex.org/W2161788422","https://openalex.org/W2161978513","https://openalex.org/W2163822360","https://openalex.org/W2165534500","https://openalex.org/W2166964423","https://openalex.org/W2167235467","https://openalex.org/W2168940882","https://openalex.org/W2169375351","https://openalex.org/W2170139402","https://openalex.org/W2170364292","https://openalex.org/W2171979944","https://openalex.org/W2178331820","https://openalex.org/W2196443441","https://openalex.org/W2202752993","https://openalex.org/W2340678277","https://openalex.org/W2461364367","https://openalex.org/W2464286578","https://openalex.org/W2469138271","https://openalex.org/W4231375398","https://openalex.org/W4243019843","https://openalex.org/W4256362156","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2100808635","https://openalex.org/W3133779420","https://openalex.org/W2108461880","https://openalex.org/W640098701","https://openalex.org/W2031080879","https://openalex.org/W2118522365","https://openalex.org/W1941431053","https://openalex.org/W2092322112","https://openalex.org/W2103866782","https://openalex.org/W2103650142"],"abstract_inverted_index":{"Initially":[0],"discovered":[1],"in":[2,10,65,70,110,115,137,184,187,195,211],"the":[3,11,45,50,83,87,98,174,207,217],"context":[4],"of":[5,14,47,77,122,176,180,190,206,219],"photosynthesis,":[6],"regulation":[7,71,116,175],"by":[8,58,105,147],"change":[9],"redox":[12,172,209],"state":[13],"thiol":[15],"groups":[16],"(S\u2212S":[17],"\u2194":[18],"2SH)":[19],"is":[20,63,108],"now":[21],"known":[22],"to":[23,34,40,142,173,201,215,222],"occur":[24],"throughout":[25],"biology.":[26],"Several":[27],"systems,":[28],"each":[29],"linking":[30],"a":[31,53,80,92,101,126,203],"hydrogen":[32],"donor":[33],"an":[35,177],"intermediary":[36],"disulfide":[37,130,133],"protein,":[38,55,103,131],"act":[39],"effect":[41],"changes":[42],"that":[43,62,107],"alter":[44],"activity":[46],"target":[48],"proteins:":[49],"ferredoxin/":[51],"thioredoxin":[52],"small":[54,102],"reduced":[56,78,104,123],"enzymatically":[57],"NADPH":[59],"or":[60,72,117],"ferredoxin,":[61,79],"active":[64,109],"thiol/disulfide":[66,111],"exchange":[67,112],"and":[68,82,94,97,113,125,144,157,214,224],"results":[69,114],"substrate":[73,118],"conversion":[74,119],"system,":[75,89,120],"comprised":[76],"thioredoxin,":[81,93],"enzyme,":[84],"ferredoxin-thioredoxin":[85],"reductase;":[86,96],"NADP/thioredoxin":[88],"including":[90],"NADPH,":[91],"NADP-thioredoxin":[95],"glutathione/":[99],"glutaredoxin":[100],"glutathione,":[106],"composed":[121],"glutathione":[124],"glutaredoxin.":[127],"A":[128],"related":[129],"protein":[132,138],"isomerase":[134],"(PDI)":[135],"acts":[136],"assembly.":[139],"Regulation":[140],"linked":[141,171],"plastoquinone":[143],"signaling":[145],"induced":[146],"reactive":[148,153],"oxygen":[149,154],"species":[150,155],"(":[151],"ROS":[152],")":[156],"other":[158,188],"agents":[159],"are":[160],"also":[161],"being":[162],"actively":[163],"investigated.":[164],"Progress":[165],"made":[166],"on":[167],"these":[168],"systems":[169],"has":[170],"increasing":[178],"number":[179],"processes":[181],"not":[182],"only":[183],"plants,":[185],"but":[186],"types":[189],"organisms":[191],"as":[192],"well.":[193],"Research":[194],"areas":[196],"currently":[197],"under":[198],"exploration":[199],"promises":[200],"provide":[202],"fuller":[204],"understanding":[205],"role":[208],"plays":[210],"cellular":[212],"processes,":[213],"further":[216],"application":[218],"this":[220],"knowledge":[221],"technology":[223],"medicine.":[225]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":20},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":23},{"year":2022,"cited_by_count":23},{"year":2021,"cited_by_count":54},{"year":2020,"cited_by_count":34},{"year":2019,"cited_by_count":29},{"year":2018,"cited_by_count":30},{"year":2017,"cited_by_count":33},{"year":2016,"cited_by_count":40},{"year":2015,"cited_by_count":44},{"year":2014,"cited_by_count":49},{"year":2013,"cited_by_count":65},{"year":2012,"cited_by_count":60}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}