{"id":"https://openalex.org/W2149257902","doi":"https://doi.org/10.1586/14737159.6.4.519","title":"APTIMA\u00aetranscription-mediated amplification assays forChlamydia trachomatisandNeisseria gonorrhoeae","display_name":"APTIMA\u00aetranscription-mediated amplification assays forChlamydia trachomatisandNeisseria gonorrhoeae","publication_year":2006,"publication_date":"2006-07-01","ids":{"openalex":"https://openalex.org/W2149257902","doi":"https://doi.org/10.1586/14737159.6.4.519","mag":"2149257902","pmid":"https://pubmed.ncbi.nlm.nih.gov/16824026"},"language":"en","primary_location":{"id":"doi:10.1586/14737159.6.4.519","doi":"https://doi.org/10.1586/14737159.6.4.519","is_oa":false,"landing_page_url":"https://doi.org/10.1586/14737159.6.4.519","pdf_url":null,"source":{"id":"https://openalex.org/S124386304","display_name":"Expert Review of Molecular Diagnostics","issn_l":"1473-7159","issn":["1473-7159","1744-8352"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Molecular Diagnostics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080857195","display_name":"Max Chernesky","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Max A Chernesky","raw_affiliation_strings":["McMaster University, St. Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada. chernesk@mcmaster.ca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McMaster University, St. Joseph's Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada. chernesk@mcmaster.ca","institution_ids":["https://openalex.org/I98251732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111962837","display_name":"Dan Jang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Dan E Jang","raw_affiliation_strings":["Research Coordinator, McMaster University, St. Joseph\u2019s Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada. jangd@mcmaster.ca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Coordinator, McMaster University, St. Joseph\u2019s Healthcare, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada. jangd@mcmaster.ca","institution_ids":["https://openalex.org/I98251732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I98251732"],"apc_list":null,"apc_paid":null,"fwci":1.6352,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.78294671,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"6","issue":"4","first_page":"519","last_page":"525"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcription-mediated-amplification","display_name":"transcription-mediated amplification","score":0.9909999966621399},{"id":"https://openalex.org/keywords/chlamydia-trachomatis","display_name":"Chlamydia trachomatis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/neisseria-gonorrhoeae","display_name":"Neisseria gonorrhoeae","score":1.0},{"id":"https://openalex.org/keywords/nucleic-acid-amplification-testing","display_name":"nucleic acid amplification tests","score":0.8809999823570251},{"id":"https://openalex.org/keywords/sexually-transmitted-infections","display_name":"sexually transmitted infections","score":0.7350000143051147},{"id":"https://openalex.org/keywords/self-collected-samples","display_name":"self-collected samples","score":0.6430000066757202},{"id":"https://openalex.org/keywords/diagnostic-sensitivity","display_name":"diagnostic sensitivity","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C2777391075","wikidata":"https://www.wikidata.org/wiki/Q131065","display_name":"Chlamydia trachomatis","level":2,"score":0.9573806524276733},{"id":"https://openalex.org/C2779166590","wikidata":"https://www.wikidata.org/wiki/Q131129","display_name":"Neisseria gonorrhoeae","level":2,"score":0.945927619934082},{"id":"https://openalex.org/C2909633786","wikidata":"https://www.wikidata.org/wiki/Q348667","display_name":"Nucleic Acid Amplification Tests","level":3,"score":0.8650941848754883},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.6572497487068176},{"id":"https://openalex.org/C2780122209","wikidata":"https://www.wikidata.org/wiki/Q153356","display_name":"Chlamydia","level":2,"score":0.6504307985305786},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5584332942962646},{"id":"https://openalex.org/C2777038808","wikidata":"https://www.wikidata.org/wiki/Q13474598","display_name":"Chlamydiaceae","level":3,"score":0.5177892446517944},{"id":"https://openalex.org/C2778651837","wikidata":"https://www.wikidata.org/wiki/Q5102716","display_name":"Chlamydiales","level":3,"score":0.5036076903343201},{"id":"https://openalex.org/C47558249","wikidata":"https://www.wikidata.org/wiki/Q1422343","display_name":"Ligase chain reaction","level":5,"score":0.45632389187812805},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.41794413328170776},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.36520659923553467},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.30383145809173584},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.22510024905204773},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16096365451812744},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07828778028488159},{"id":"https://openalex.org/C90583042","wikidata":"https://www.wikidata.org/wiki/Q1952456","display_name":"Multiplex polymerase chain reaction","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D002690","descriptor_name":"Chlamydia Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006069","descriptor_name":"Gonorrhea","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009344","descriptor_name":"Neisseria gonorrhoeae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011933","descriptor_name":"Reagent Kits, Diagnostic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012749","descriptor_name":"Sexually Transmitted Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021141","descriptor_name":"Nucleic Acid Amplification Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1586/14737159.6.4.519","doi":"https://doi.org/10.1586/14737159.6.4.519","is_oa":false,"landing_page_url":"https://doi.org/10.1586/14737159.6.4.519","pdf_url":null,"source":{"id":"https://openalex.org/S124386304","display_name":"Expert Review of Molecular Diagnostics","issn_l":"1473-7159","issn":["1473-7159","1744-8352"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert Review of Molecular Diagnostics","raw_type":"journal-article"},{"id":"pmid:16824026","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16824026","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Expert review of molecular diagnostics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1776525723","https://openalex.org/W2009360170","https://openalex.org/W2016474373","https://openalex.org/W2019922928","https://openalex.org/W2042891164","https://openalex.org/W2073126219","https://openalex.org/W2082068058","https://openalex.org/W2099484649","https://openalex.org/W2131272750","https://openalex.org/W2133343551","https://openalex.org/W2136449727","https://openalex.org/W2147922084","https://openalex.org/W2154858664","https://openalex.org/W2157947741","https://openalex.org/W2159394834","https://openalex.org/W2171584441"],"related_works":["https://openalex.org/W2171584441","https://openalex.org/W7095785969","https://openalex.org/W2154858664","https://openalex.org/W2147922084","https://openalex.org/W7100700668","https://openalex.org/W2003581200","https://openalex.org/W2607352749","https://openalex.org/W2042891164","https://openalex.org/W1996846893","https://openalex.org/W2073126219"],"abstract_inverted_index":{"The":[0],"APTIMA":[1],"transcription-mediated":[2],"amplification":[3,21,80],"assays":[4,96],"for":[5,23,82],"Chlamydia":[6],"trachomatis":[7],"and":[8,46,70],"Neisseria":[9],"gonorrhoeae":[10],"have":[11,40],"the":[12,17,24,59,92,95],"greatest":[13],"sensitivity":[14],"of":[15,26,36,49,52,61,91],"all":[16],"commercial":[18],"nucleic":[19,37],"acid":[20],"tests":[22],"diagnosis":[25],"infections":[27],"from":[28],"noninvasive":[29],"samples":[30],"that":[31],"may":[32],"contain":[33],"small":[34],"amounts":[35],"acid.":[38],"They":[39],"received":[41],"extensive":[42],"attention":[43],"in":[44,68,73,102],"male":[45],"female":[47],"populations":[48],"varying":[50],"prevalences":[51],"infection.":[53],"Vulvovaginal":[54],"swabs":[55],"appear":[56],"to":[57,99],"be":[58,100],"specimen":[60],"choice":[62],"(either":[63],"self-collected":[64],"or":[65,84],"physician":[66],"collected)":[67],"women":[69],"first-catch":[71],"urine":[72],"men.":[74],"Gen-Probe":[75],"Inc.":[76],"has":[77],"created":[78],"alternate":[79],"primers":[81],"confirmatory":[83],"initial":[85],"single":[86],"organism":[87],"testing.":[88],"With":[89],"automation":[90],"TIGRIS":[93],"instrument,":[94],"should":[97],"prove":[98],"useful":[101],"high-volume":[103],"laboratories.":[104]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}