{"id":"https://openalex.org/W2149094101","doi":"https://doi.org/10.1042/bj20030533","title":"Ribonuclease III-mediated processing of specific Neisseria meningitidis mRNAs","display_name":"Ribonuclease III-mediated processing of specific Neisseria meningitidis mRNAs","publication_year":2003,"publication_date":"2003-09-08","ids":{"openalex":"https://openalex.org/W2149094101","doi":"https://doi.org/10.1042/bj20030533","mag":"2149094101","pmid":"https://pubmed.ncbi.nlm.nih.gov/12826014","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1223648"},"language":"en","primary_location":{"id":"doi:10.1042/bj20030533","doi":"https://doi.org/10.1042/bj20030533","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj20030533","pdf_url":"https://portlandpress.com/biochemj/article-pdf/374/3/799/711845/bj3740799.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://portlandpress.com/biochemj/article-pdf/374/3/799/711845/bj3740799.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008905432","display_name":"Eliana De Gregorio","orcid":"https://orcid.org/0000-0002-2529-8611","observed_orcids":["https://orcid.org/0000-0002-2529-8611"]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Eliana DE GREGORIO","raw_affiliation_strings":["Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082952444","display_name":"Chiara Abrescia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara ABRESCIA","raw_affiliation_strings":["Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108570647","display_name":"M. Stella Carlomagno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M. Stella CARLOMAGNO","raw_affiliation_strings":["Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy","institution_ids":["https://openalex.org/I71267560"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111685587","display_name":"Pier Paolo Di Nocera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Pier Paolo DI NOCERA","raw_affiliation_strings":["Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento di Biologia e Patologia Cellulare e Molecolare \u201cL. Califano\u201d, Universit\u00e0 degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy","institution_ids":["https://openalex.org/I71267560"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I71267560"],"apc_list":null,"apc_paid":null,"fwci":0.8758,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.7377113,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"374","issue":"3","first_page":"799","last_page":"805"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.8657000064849854,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.07199999690055847,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.023499999195337296,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neisseria-meningitidis","display_name":"Neisseria meningitidis","score":0.9359999895095825},{"id":"https://openalex.org/keywords/rnase-iii","display_name":"RNase III","score":0.9139999747276306},{"id":"https://openalex.org/keywords/mrna-processing","display_name":"mRNA processing","score":0.7710000276565552},{"id":"https://openalex.org/keywords/inverted-terminal-repeats","display_name":"inverted terminal repeats","score":0.8550000190734863},{"id":"https://openalex.org/keywords/rna-hairpin","display_name":"RNA hairpin","score":0.796999990940094},{"id":"https://openalex.org/keywords/double-stranded-rna","display_name":"double-stranded RNA","score":0.7200000286102295},{"id":"https://openalex.org/keywords/rna-stability","display_name":"RNA stability","score":0.46399998664855957},{"id":"https://openalex.org/keywords/cotranscription","display_name":"cotranscription","score":0.49399998784065247}],"concepts":[{"id":"https://openalex.org/C2780102198","wikidata":"https://www.wikidata.org/wiki/Q3054027","display_name":"Endoribonuclease","level":5,"score":0.7830899953842163},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.7752289772033691},{"id":"https://openalex.org/C10879258","wikidata":"https://www.wikidata.org/wiki/Q76826611","display_name":"RNase P","level":4,"score":0.7251378297805786},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6469970941543579},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6408030986785889},{"id":"https://openalex.org/C51603236","wikidata":"https://www.wikidata.org/wiki/Q4852694","display_name":"Inverted repeat","level":4,"score":0.5747908353805542},{"id":"https://openalex.org/C29511175","wikidata":"https://www.wikidata.org/wiki/Q5280381","display_name":"Direct repeat","level":4,"score":0.5685662031173706},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5440125465393066},{"id":"https://openalex.org/C2778458888","wikidata":"https://www.wikidata.org/wiki/Q154625","display_name":"Neisseria meningitidis","level":3,"score":0.5091373324394226},{"id":"https://openalex.org/C2778976237","wikidata":"https://www.wikidata.org/wiki/Q422523","display_name":"Ribonuclease","level":4,"score":0.5016725063323975},{"id":"https://openalex.org/C69766542","wikidata":"https://www.wikidata.org/wiki/Q3430179","display_name":"RNase H","level":5,"score":0.48577001690864563},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4311200976371765},{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.4294396638870239},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.3423486351966858},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.32495883107185364},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.07612797617912292}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004722","descriptor_name":"Endoribonucleases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009345","descriptor_name":"Neisseria meningitidis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012323","descriptor_name":"RNA Processing, Post-Transcriptional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016366","descriptor_name":"Open Reading Frames","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020079","descriptor_name":"Terminal Repeat Sequences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020086","descriptor_name":"Short Interspersed Nucleotide Elements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020871","descriptor_name":"RNA Stability","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D043244","descriptor_name":"Ribonuclease III","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1042/bj20030533","doi":"https://doi.org/10.1042/bj20030533","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj20030533","pdf_url":"https://portlandpress.com/biochemj/article-pdf/374/3/799/711845/bj3740799.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1223648","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1223648","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochem J","raw_type":"Text"},{"id":"pmid:12826014","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12826014","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Biochemical journal","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unito.it:2318/1627699","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2318/1627699","pdf_url":null,"source":{"id":"https://openalex.org/S4306400637","display_name":"Institutional Research Information System University of Turin (University of Turin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I55143463","host_organization_name":"University of Turin","host_organization_lineage":["https://openalex.org/I55143463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1042/bj20030533","doi":"https://doi.org/10.1042/bj20030533","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj20030533","pdf_url":"https://portlandpress.com/biochemj/article-pdf/374/3/799/711845/bj3740799.pdf","source":{"id":"https://openalex.org/S44425019","display_name":"Biochemical Journal","issn_l":"0264-6021","issn":["0264-6021","1470-8728"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2149094101.pdf","grobid_xml":"https://content.openalex.org/works/W2149094101.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W893915","https://openalex.org/W1514067978","https://openalex.org/W1525643420","https://openalex.org/W1527772770","https://openalex.org/W1971129779","https://openalex.org/W1971143693","https://openalex.org/W1986897865","https://openalex.org/W1989011168","https://openalex.org/W1996616626","https://openalex.org/W2011847079","https://openalex.org/W2013005072","https://openalex.org/W2017313617","https://openalex.org/W2024895709","https://openalex.org/W2025124184","https://openalex.org/W2026430354","https://openalex.org/W2043296204","https://openalex.org/W2054334919","https://openalex.org/W2054778806","https://openalex.org/W2080100789","https://openalex.org/W2080724113","https://openalex.org/W2080885816","https://openalex.org/W2084416980","https://openalex.org/W2092383666","https://openalex.org/W2097639650","https://openalex.org/W2108462386","https://openalex.org/W2113616421","https://openalex.org/W2124584113","https://openalex.org/W2127335580","https://openalex.org/W2128161048","https://openalex.org/W2133305872","https://openalex.org/W2142503351","https://openalex.org/W2145694918","https://openalex.org/W2167969408","https://openalex.org/W4245519835"],"related_works":["https://openalex.org/W2084416980","https://openalex.org/W2028702182","https://openalex.org/W2004028197","https://openalex.org/W1996383736","https://openalex.org/W2038759280","https://openalex.org/W2012258341","https://openalex.org/W2162575120","https://openalex.org/W2091441982","https://openalex.org/W1970064787","https://openalex.org/W2058070874"],"abstract_inverted_index":{"Approx.":[0],"2%":[1],"of":[2,8,25,112,122],"the":[3,68,119],"Neisseria":[4],"meningitidis":[5,51],"genome":[6],"consists":[7],"small":[9],"DNA":[10],"insertion":[11],"sequences":[12],"known":[13],"as":[14],"Correia":[15],"or":[16],"nemis":[17,66],"elements,":[18],"which":[19],"feature":[20],"TIRs":[21],"(terminal":[22],"inverted":[23],"repeats)":[24,74],"26-27":[26],"bp":[27],"in":[28,88,91,129],"length.":[29],"Elements":[30],"interspersed":[31],"with":[32,37,67,107],"coding":[33],"regions":[34],"are":[35,75],"co-transcribed":[36],"flanking":[38],"genes":[39],"into":[40],"mRNAs,":[41,117],"processed":[42,125],"at":[43],"double-stranded":[44],"RNA":[45,62,123],"structures":[46],"formed":[47,64,81,101],"by":[48,65,82],"TIRs.":[49],"N.":[50],"RNase":[52,108],"III":[53],"(endoribonuclease":[54],"III)":[55],"is":[56],"sufficient":[57],"to":[58],"process":[59],"nemis+":[60,114,127],"RNAs.":[61],"hairpins":[63,80],"same":[69],"termini":[70],"(26/26":[71],"and":[72,90,115,118],"27/27":[73],"cleaved.":[76],"By":[77],"contrast,":[78],"bulged":[79],"26/27":[83],"repeats":[84],"inhibit":[85],"cleavage,":[86],"both":[87,132],"vitro":[89],"vivo.":[92],"In":[93],"electrophoretic":[94],"mobility":[95],"shift":[96],"assays,":[97],"all":[98],"hairpin":[99],"types":[100],"similar":[102],"retarded":[103],"complexes":[104],"upon":[105],"incubation":[106],"III.":[109],"The":[110],"levels":[111],"corresponding":[113],"nemis-":[116],"relative":[120],"stabilities":[121],"segments":[124],"from":[126],"transcripts":[128],"vitro,":[130],"may":[131],"vary":[133],"significantly.":[134]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}