{"id":"https://openalex.org/W2149081087","doi":"https://doi.org/10.1002/anie.200906670","title":"Amyloidogenic Protein\u2013Membrane Interactions: Mechanistic Insight from Model Systems","display_name":"Amyloidogenic Protein\u2013Membrane Interactions: Mechanistic Insight from Model Systems","publication_year":2010,"publication_date":"2010-07-12","ids":{"openalex":"https://openalex.org/W2149081087","doi":"https://doi.org/10.1002/anie.200906670","mag":"2149081087","pmid":"https://pubmed.ncbi.nlm.nih.gov/20623810"},"language":"en","primary_location":{"id":"doi:10.1002/anie.200906670","doi":"https://doi.org/10.1002/anie.200906670","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anie.200906670","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anie.200906670","source":{"id":"https://openalex.org/S67393510","display_name":"Angewandte Chemie International Edition","issn_l":"1433-7851","issn":["1433-7851","1521-3773"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie International Edition","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anie.200906670","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021480202","display_name":"Sara M. Butterfield","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Sara\u2005M. Butterfield","raw_affiliation_strings":["Laboratory of Molecular Neurobiology and Neuroproteomics, Swiss Federal Institute of Technology Lausanne (EPFL), SV-BMI-LMNN AI2351, 1015 Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Neurobiology and Neuroproteomics, Swiss Federal Institute of Technology Lausanne (EPFL), SV-BMI-LMNN AI2351, 1015 Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086170675","display_name":"Hilal Ahmed Lashuel","orcid":"https://orcid.org/0000-0001-7682-8320","observed_orcids":["https://orcid.org/0000-0001-7682-8320","https://orcid.org/0000-0002-3737-1054"]},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Hilal\u2005A. Lashuel","raw_affiliation_strings":["Laboratory of Molecular Neurobiology and Neuroproteomics, Swiss Federal Institute of Technology Lausanne (EPFL), SV-BMI-LMNN AI2351, 1015 Lausanne (Switzerland)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Neurobiology and Neuroproteomics, Swiss Federal Institute of Technology Lausanne (EPFL), SV-BMI-LMNN AI2351, 1015 Lausanne (Switzerland)","institution_ids":["https://openalex.org/I5124864"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I5124864"],"apc_list":{"value":5510,"currency":"USD","value_usd":5510},"apc_paid":null,"fwci":3.7961,"has_fulltext":false,"cited_by_count":594,"citation_normalized_percentile":{"value":0.96252231,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"49","issue":"33","first_page":"5628","last_page":"5654"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.7368000149726868,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.7368000149726868,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.2061000019311905,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyloidogenic-proteins","display_name":"amyloidogenic proteins","score":0.9620000123977661},{"id":"https://openalex.org/keywords/protein-membrane-interactions","display_name":"protein-membrane interactions","score":0.984000027179718},{"id":"https://openalex.org/keywords/protein-aggregation","display_name":"protein aggregation","score":0.6230000257492065},{"id":"https://openalex.org/keywords/protein-toxicity","display_name":"protein toxicity","score":0.6259999871253967},{"id":"https://openalex.org/keywords/pore-forming-toxins","display_name":"pore-forming toxins","score":0.9829999804496765},{"id":"https://openalex.org/keywords/antimicrobial-peptides","display_name":"antimicrobial peptides","score":0.9829999804496765}],"concepts":[{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.7794874310493469},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.5958051681518555},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5596555471420288},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5277674198150635},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.4588108956813812},{"id":"https://openalex.org/C2778106830","wikidata":"https://www.wikidata.org/wiki/Q29548","display_name":"Cell membrane","level":3,"score":0.43362003564834595},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4247640371322632},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.42468786239624023},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3877091407775879},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.27600908279418945},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000682","descriptor_name":"Amyloid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000682","descriptor_name":"Amyloid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002462","descriptor_name":"Cell Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008670","descriptor_name":"Metals","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016229","descriptor_name":"Amyloid beta-Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051843","descriptor_name":"Synucleins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051843","descriptor_name":"Synucleins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D058228","descriptor_name":"Islet Amyloid Polypeptide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D058228","descriptor_name":"Islet Amyloid Polypeptide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/anie.200906670","doi":"https://doi.org/10.1002/anie.200906670","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anie.200906670","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anie.200906670","source":{"id":"https://openalex.org/S67393510","display_name":"Angewandte Chemie International Edition","issn_l":"1433-7851","issn":["1433-7851","1521-3773"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie International Edition","raw_type":"journal-article"},{"id":"pmid:20623810","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20623810","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie (International ed. in English)","raw_type":"Journal Article"},{"id":"pmh:oai:infoscience.epfl.ch:142971","doi":null,"is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/142971","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5124864","host_organization_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","host_organization_lineage":["https://openalex.org/I5124864"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:infoscience.tind.io:142971","doi":null,"is_oa":true,"landing_page_url":"https://infoscience.epfl.ch/handle/20.500.14299/45022","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I5124864","host_organization_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","host_organization_lineage":["https://openalex.org/I5124864"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"research article"}],"best_oa_location":{"id":"doi:10.1002/anie.200906670","doi":"https://doi.org/10.1002/anie.200906670","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anie.200906670","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anie.200906670","source":{"id":"https://openalex.org/S67393510","display_name":"Angewandte Chemie International Edition","issn_l":"1433-7851","issn":["1433-7851","1521-3773"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Angewandte Chemie International Edition","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.504800021648407,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2149081087.pdf"},"referenced_works_count":227,"referenced_works":["https://openalex.org/W55338515","https://openalex.org/W138075717","https://openalex.org/W167632067","https://openalex.org/W1480108665","https://openalex.org/W1527671059","https://openalex.org/W1538748480","https://openalex.org/W1549706479","https://openalex.org/W1602771322","https://openalex.org/W1608388154","https://openalex.org/W1661503297","https://openalex.org/W1672697155","https://openalex.org/W1678350171","https://openalex.org/W1780764429","https://openalex.org/W1963969470","https://openalex.org/W1964352658","https://openalex.org/W1964549663","https://openalex.org/W1966774118","https://openalex.org/W1966788000","https://openalex.org/W1966833359","https://openalex.org/W1967530447","https://openalex.org/W1969130034","https://openalex.org/W1969553345","https://openalex.org/W1969800972","https://openalex.org/W1971419973","https://openalex.org/W1972535964","https://openalex.org/W1974700363","https://openalex.org/W1976130701","https://openalex.org/W1977317129","https://openalex.org/W1978629513","https://openalex.org/W1978865621","https://openalex.org/W1980028783","https://openalex.org/W1980035515","https://openalex.org/W1981580199","https://openalex.org/W1982625489","https://openalex.org/W1982663316","https://openalex.org/W1982920217","https://openalex.org/W1984252627","https://openalex.org/W1985889569","https://openalex.org/W1986050360","https://openalex.org/W1986123213","https://openalex.org/W1986376919","https://openalex.org/W1986568955","https://openalex.org/W1989176019","https://openalex.org/W1989451255","https://openalex.org/W1990749733","https://openalex.org/W1991241547","https://openalex.org/W1991335320","https://openalex.org/W1991655565","https://openalex.org/W1992989385","https://openalex.org/W1993772503","https://openalex.org/W1994342334","https://openalex.org/W1994398814","https://openalex.org/W1995309381","https://openalex.org/W1996627364","https://openalex.org/W1999157426","https://openalex.org/W1999311792","https://openalex.org/W2000956229","https://openalex.org/W2002089999","https://openalex.org/W2002288900","https://openalex.org/W2002768329","https://openalex.org/W2002837229","https://openalex.org/W2002911779","https://openalex.org/W2004174312","https://openalex.org/W2004261895","https://openalex.org/W2005568374","https://openalex.org/W2005984783","https://openalex.org/W2006528692","https://openalex.org/W2006790257","https://openalex.org/W2007003497","https://openalex.org/W2007505743","https://openalex.org/W2008165517","https://openalex.org/W2008812223","https://openalex.org/W2010531966","https://openalex.org/W2011771839","https://openalex.org/W2017114341","https://openalex.org/W2017484368","https://openalex.org/W2017905166","https://openalex.org/W2018080238","https://openalex.org/W2018990453","https://openalex.org/W2020340473","https://openalex.org/W2020550176","https://openalex.org/W2020796799","https://openalex.org/W2022428567","https://openalex.org/W2022654678","https://openalex.org/W2023245921","https://openalex.org/W2023781813","https://openalex.org/W2024313783","https://openalex.org/W2024529817","https://openalex.org/W2024849831","https://openalex.org/W2026380581","https://openalex.org/W2026665110","https://openalex.org/W2026714067","https://openalex.org/W2026821359","https://openalex.org/W2028079079","https://openalex.org/W2029422688","https://openalex.org/W2029428787","https://openalex.org/W2029593286","https://openalex.org/W2030754541","https://openalex.org/W2031004094","https://openalex.org/W2033451537","https://openalex.org/W2033776678","https://openalex.org/W2034600959","https://openalex.org/W2037584614","https://openalex.org/W2038391042","https://openalex.org/W2038392139","https://openalex.org/W2039049924","https://openalex.org/W2039990417","https://openalex.org/W2040054953","https://openalex.org/W2040187264","https://openalex.org/W2040388127","https://openalex.org/W2043358632","https://openalex.org/W2043951944","https://openalex.org/W2044451298","https://openalex.org/W2046704370","https://openalex.org/W2050310710","https://openalex.org/W2051489500","https://openalex.org/W2051509234","https://openalex.org/W2052216167","https://openalex.org/W2052685422","https://openalex.org/W2052913704","https://openalex.org/W2053402937","https://openalex.org/W2053434304","https://openalex.org/W2054043866","https://openalex.org/W2055462017","https://openalex.org/W2058930537","https://openalex.org/W2061245389","https://openalex.org/W2061742728","https://openalex.org/W2061836867","https://openalex.org/W2062609628","https://openalex.org/W2062761462","https://openalex.org/W2062990728","https://openalex.org/W2065533951","https://openalex.org/W2065660960","https://openalex.org/W2066253841","https://openalex.org/W2066483080","https://openalex.org/W2066767743","https://openalex.org/W2067008646","https://openalex.org/W2067088461","https://openalex.org/W2067132703","https://openalex.org/W2068518064","https://openalex.org/W2068934053","https://openalex.org/W2070114315","https://openalex.org/W2072250256","https://openalex.org/W2072555257","https://openalex.org/W2073686561","https://openalex.org/W2075481535","https://openalex.org/W2075930760","https://openalex.org/W2076970404","https://openalex.org/W2077044335","https://openalex.org/W2077651669","https://openalex.org/W2078777958","https://openalex.org/W2080213022","https://openalex.org/W2080319524","https://openalex.org/W2080511409","https://openalex.org/W2082038580","https://openalex.org/W2082255060","https://openalex.org/W2082844643","https://openalex.org/W2083500052","https://openalex.org/W2083920564","https://openalex.org/W2084280842","https://openalex.org/W2084533538","https://openalex.org/W2084574939","https://openalex.org/W2085287800","https://openalex.org/W2085538443","https://openalex.org/W2086278983","https://openalex.org/W2087389265","https://openalex.org/W2087861584","https://openalex.org/W2088777230","https://openalex.org/W2093713022","https://openalex.org/W2094525223","https://openalex.org/W2096336861","https://openalex.org/W2100216915","https://openalex.org/W2100817247","https://openalex.org/W2101731922","https://openalex.org/W2103435773","https://openalex.org/W2105488386","https://openalex.org/W2105949921","https://openalex.org/W2106874569","https://openalex.org/W2113115394","https://openalex.org/W2113472155","https://openalex.org/W2118134410","https://openalex.org/W2120413823","https://openalex.org/W2122000410","https://openalex.org/W2125642980","https://openalex.org/W2125730116","https://openalex.org/W2126257901","https://openalex.org/W2129583700","https://openalex.org/W2130111915","https://openalex.org/W2130137989","https://openalex.org/W2131909172","https://openalex.org/W2133272695","https://openalex.org/W2134843571","https://openalex.org/W2134909516","https://openalex.org/W2135560234","https://openalex.org/W2136012285","https://openalex.org/W2136659930","https://openalex.org/W2137204463","https://openalex.org/W2137786650","https://openalex.org/W2138375082","https://openalex.org/W2141035467","https://openalex.org/W2141405942","https://openalex.org/W2141536611","https://openalex.org/W2143598658","https://openalex.org/W2144892927","https://openalex.org/W2146715943","https://openalex.org/W2147226356","https://openalex.org/W2147543171","https://openalex.org/W2147745956","https://openalex.org/W2148068824","https://openalex.org/W2148321634","https://openalex.org/W2148828302","https://openalex.org/W2150029647","https://openalex.org/W2150999725","https://openalex.org/W2152419135","https://openalex.org/W2155477793","https://openalex.org/W2155653247","https://openalex.org/W2160497181","https://openalex.org/W2160664224","https://openalex.org/W2164724082","https://openalex.org/W2165186407","https://openalex.org/W2168715581","https://openalex.org/W2170843000","https://openalex.org/W2415048110","https://openalex.org/W3135190686","https://openalex.org/W3140746781","https://openalex.org/W4210958643","https://openalex.org/W4320800140"],"related_works":["https://openalex.org/W2120532320","https://openalex.org/W1972359874","https://openalex.org/W2949259850","https://openalex.org/W2068578172","https://openalex.org/W2410588071","https://openalex.org/W2052685422","https://openalex.org/W2060952580","https://openalex.org/W2416440171","https://openalex.org/W2314096001","https://openalex.org/W3143552619"],"abstract_inverted_index":{"The":[0],"toxicity":[1],"of":[2,36,51,66,69,72,77],"amyloid-forming":[3,37,73],"proteins":[4,17,38,74],"is":[5],"correlated":[6],"with":[7,10,29,57],"their":[8],"interactions":[9],"cell":[11,53],"membranes.":[12],"Binding":[13],"events":[14],"between":[15],"amyloidogenic":[16,43],"and":[18,42,80],"membranes":[19,60],"result":[20],"in":[21,45],"mutually":[22],"disruptive":[23],"structural":[24,49],"perturbations,":[25],"which":[26],"are":[27],"associated":[28],"toxicity.":[30],"Membrane":[31],"surfaces":[32],"promote":[33],"the":[34,48,52,63,67],"conversion":[35],"into":[39],"toxic":[40],"aggregates,":[41],"proteins,":[44],"turn,":[46],"compromise":[47],"integrity":[50],"membrane.":[54],"Recent":[55],"studies":[56],"artificial":[58],"model":[59],"have":[61],"highlighted":[62],"striking":[64],"resemblance":[65],"mechanisms":[68],"membrane":[70],"permeabilization":[71],"to":[75],"those":[76],"pore-forming":[78],"toxins":[79],"antimicrobial":[81],"peptides.":[82]},"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":26},{"year":2023,"cited_by_count":27},{"year":2022,"cited_by_count":27},{"year":2021,"cited_by_count":57},{"year":2020,"cited_by_count":53},{"year":2019,"cited_by_count":36},{"year":2018,"cited_by_count":51},{"year":2017,"cited_by_count":29},{"year":2016,"cited_by_count":35},{"year":2015,"cited_by_count":53},{"year":2014,"cited_by_count":51},{"year":2013,"cited_by_count":47},{"year":2012,"cited_by_count":44}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}