{"id":"https://openalex.org/W2149048076","doi":"https://doi.org/10.1007/4-431-29402-3_27","title":"Detection of the Prion Protein in a Liquid Phase Capture Assay Using Magnetic Beads Coupled to Protein A","display_name":"Detection of the Prion Protein in a Liquid Phase Capture Assay Using Magnetic Beads Coupled to Protein A","publication_year":2006,"publication_date":"2006-06-08","ids":{"openalex":"https://openalex.org/W2149048076","doi":"https://doi.org/10.1007/4-431-29402-3_27","mag":"2149048076"},"language":"en","primary_location":{"id":"doi:10.1007/4-431-29402-3_27","doi":"https://doi.org/10.1007/4-431-29402-3_27","is_oa":false,"landing_page_url":"https://doi.org/10.1007/4-431-29402-3_27","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prions","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4236545241","display_name":"Prions"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054112022","display_name":"Wen\u2010Chu Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]},{"id":"https://openalex.org/I2802789608","display_name":"Ames National Laboratory","ror":"https://ror.org/041m9xr71","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I173911158","https://openalex.org/I2802789608","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen-Chu Yang","raw_affiliation_strings":["Ames Laboratory, Iowa State University, Ames, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ames Laboratory, Iowa State University, Ames, USA","institution_ids":["https://openalex.org/I173911158","https://openalex.org/I2802789608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061282830","display_name":"Edward S. Yeung","orcid":"https://orcid.org/0000-0003-0919-6700","observed_orcids":["https://orcid.org/0000-0003-0919-6700"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]},{"id":"https://openalex.org/I2802789608","display_name":"Ames National Laboratory","ror":"https://ror.org/041m9xr71","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I173911158","https://openalex.org/I2802789608","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward S. Yeung","raw_affiliation_strings":["Ames Laboratory, Iowa State University, Ames, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ames Laboratory, Iowa State University, Ames, USA","institution_ids":["https://openalex.org/I173911158","https://openalex.org/I2802789608"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110066283","display_name":"Mary Jo Schmerr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]},{"id":"https://openalex.org/I2802789608","display_name":"Ames National Laboratory","ror":"https://ror.org/041m9xr71","country_code":"US","type":"facility","lineage":["https://openalex.org/I1330989302","https://openalex.org/I173911158","https://openalex.org/I2802789608","https://openalex.org/I39565521"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary Jo Schmerr","raw_affiliation_strings":["Ames Laboratory, Iowa State University, Ames, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ames Laboratory, Iowa State University, Ames, USA","institution_ids":["https://openalex.org/I173911158","https://openalex.org/I2802789608"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062602537","display_name":"Walter Bodemer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801496451","display_name":"German Primate Center","ror":"https://ror.org/02f99v835","country_code":"DE","type":"facility","lineage":["https://openalex.org/I2801496451","https://openalex.org/I315704651"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Walter Bodemer","raw_affiliation_strings":["German Primate Center, G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"German Primate Center, G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I2801496451"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11001048,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"199","last_page":"200"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11305","display_name":"Amyloidosis: Diagnosis, Treatment, Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/abnormal-prion-protein","display_name":"abnormal prion protein","score":0.8140000104904175},{"id":"https://openalex.org/keywords/prion-disease","display_name":"prion disease","score":0.9760000109672546},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"cerebrospinal fluid","score":0.8619999885559082},{"id":"https://openalex.org/keywords/magnetic-beads","display_name":"magnetic beads","score":0.7089999914169312},{"id":"https://openalex.org/keywords/protein-a","display_name":"protein A","score":0.6859999895095825},{"id":"https://openalex.org/keywords/fluorescence-immunoassay","display_name":"fluorescence immunoassay","score":0.9039999842643738},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.8479999899864197},{"id":"https://openalex.org/keywords/sheep-scrapie","display_name":"sheep scrapie","score":0.9340000152587891},{"id":"https://openalex.org/keywords/capillary-electrophoresis","display_name":"capillary electrophoresis","score":0.6800000071525574},{"id":"https://openalex.org/keywords/proteinase-k-digestion","display_name":"proteinase K digestion","score":0.5389999747276306},{"id":"https://openalex.org/keywords/hexafluoroisopropanol","display_name":"hexafluoroisopropanol","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.6630907654762268},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6003038883209229},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5972397327423096},{"id":"https://openalex.org/C2778015030","wikidata":"https://www.wikidata.org/wiki/Q410922","display_name":"Fluorescein","level":3,"score":0.5623788237571716},{"id":"https://openalex.org/C86807702","wikidata":"https://www.wikidata.org/wiki/Q2620381","display_name":"Bovine serum albumin","level":2,"score":0.5457945466041565},{"id":"https://openalex.org/C160845552","wikidata":"https://www.wikidata.org/wiki/Q247562","display_name":"Bradford protein assay","level":2,"score":0.48691117763519287},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.46143436431884766},{"id":"https://openalex.org/C2900643","wikidata":"https://www.wikidata.org/wiki/Q747468","display_name":"Capillary electrophoresis","level":2,"score":0.45958155393600464},{"id":"https://openalex.org/C2780420688","wikidata":"https://www.wikidata.org/wiki/Q759183","display_name":"Immunoassay","level":3,"score":0.4446464776992798},{"id":"https://openalex.org/C2778285947","wikidata":"https://www.wikidata.org/wiki/Q548079","display_name":"Buffy coat","level":2,"score":0.41256970167160034},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.3285471200942993},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3163212239742279},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19894161820411682},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1903926134109497},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.07155478000640869},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/4-431-29402-3_27","doi":"https://doi.org/10.1007/4-431-29402-3_27","is_oa":false,"landing_page_url":"https://doi.org/10.1007/4-431-29402-3_27","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prions","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1993298350","https://openalex.org/W1586660941","https://openalex.org/W2091350553","https://openalex.org/W2035563977","https://openalex.org/W7095509186","https://openalex.org/W2074145863","https://openalex.org/W2000703103","https://openalex.org/W2020540413","https://openalex.org/W1494753015","https://openalex.org/W7096300849"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}