{"id":"https://openalex.org/W2148992134","doi":"https://doi.org/10.1128/jcm.23.2.333-338.1986","title":"Serovar determination of Chlamydia trachomatis isolates by using type-specific monoclonal antibodies","display_name":"Serovar determination of Chlamydia trachomatis isolates by using type-specific monoclonal antibodies","publication_year":1986,"publication_date":"1986-02-01","ids":{"openalex":"https://openalex.org/W2148992134","doi":"https://doi.org/10.1128/jcm.23.2.333-338.1986","mag":"2148992134","pmid":"https://pubmed.ncbi.nlm.nih.gov/2422202","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/268637"},"language":"en","primary_location":{"id":"doi:10.1128/jcm.23.2.333-338.1986","doi":"https://doi.org/10.1128/jcm.23.2.333-338.1986","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jcm.23.2.333-338.1986","pdf_url":null,"source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC268637/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080438647","display_name":"Wilbert J. Newhall V","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W J Newhall","raw_affiliation_strings":["Indiana University-Bloomington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University-Bloomington","institution_ids":["https://openalex.org/I4210119109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114050185","display_name":"P. Terho","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P Terho","raw_affiliation_strings":["Indiana University-Bloomington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University-Bloomington","institution_ids":["https://openalex.org/I4210119109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055376561","display_name":"Charles E. Wilde","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C E Wilde","raw_affiliation_strings":["Indiana University-Bloomington"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University-Bloomington","institution_ids":["https://openalex.org/I4210119109"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033372273","display_name":"Byron E. Batteiger","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B E Batteiger","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5053609225","display_name":"Robert B. Jones","orcid":"https://orcid.org/0000-0002-7886-8470","observed_orcids":["https://orcid.org/0000-0002-7886-8470"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R B Jones","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.0628,"has_fulltext":false,"cited_by_count":64,"citation_normalized_percentile":{"value":0.96893761,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"23","issue":"2","first_page":"333","last_page":"338"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10428","display_name":"Reproductive tract infections research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chlamydia-trachomatis","display_name":"Chlamydia trachomatis","score":1.0},{"id":"https://openalex.org/keywords/serotyping","display_name":"serotyping","score":0.8629999756813049},{"id":"https://openalex.org/keywords/monoclonal-antibodies","display_name":"monoclonal antibodies","score":0.8859999775886536},{"id":"https://openalex.org/keywords/type-specific-antibodies","display_name":"type-specific antibodies","score":0.8080000281333923},{"id":"https://openalex.org/keywords/major-outer-membrane-protein","display_name":"major outer membrane protein","score":0.9200000166893005},{"id":"https://openalex.org/keywords/antigenic-variation","display_name":"antigenic variation","score":0.906000018119812},{"id":"https://openalex.org/keywords/epitopes","display_name":"antigenic determinants","score":0.9210000038146973},{"id":"https://openalex.org/keywords/radioimmunoassay","display_name":"radioimmunoassay","score":0.8930000066757202},{"id":"https://openalex.org/keywords/microimmunofluorescence","display_name":"microimmunofluorescence","score":0.8230000138282776},{"id":"https://openalex.org/keywords/clinical-isolates","display_name":"clinical isolates","score":0.7319999933242798}],"concepts":[{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.9334172010421753},{"id":"https://openalex.org/C2777391075","wikidata":"https://www.wikidata.org/wiki/Q131065","display_name":"Chlamydia trachomatis","level":2,"score":0.8664457201957703},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.7740936279296875},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.7585830688476562},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7382470369338989},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6719746589660645},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.632827877998352},{"id":"https://openalex.org/C2777038808","wikidata":"https://www.wikidata.org/wiki/Q13474598","display_name":"Chlamydiaceae","level":3,"score":0.6105607151985168},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.5461836457252502},{"id":"https://openalex.org/C2780122209","wikidata":"https://www.wikidata.org/wiki/Q153356","display_name":"Chlamydia","level":2,"score":0.5161924958229065},{"id":"https://openalex.org/C2778651837","wikidata":"https://www.wikidata.org/wiki/Q5102716","display_name":"Chlamydiales","level":3,"score":0.4659577012062073},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.4609006643295288},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4351866841316223},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1441323459148407}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000918","descriptor_name":"Antibody Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D000942","descriptor_name":"Antigens, Bacterial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002692","descriptor_name":"Chlamydia trachomatis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007163","descriptor_name":"Immunosorbent Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012703","descriptor_name":"Serotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/jcm.23.2.333-338.1986","doi":"https://doi.org/10.1128/jcm.23.2.333-338.1986","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jcm.23.2.333-338.1986","pdf_url":null,"source":{"id":"https://openalex.org/S53087977","display_name":"Journal of Clinical Microbiology","issn_l":"0095-1137","issn":["0095-1137","1070-633X","1098-660X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Microbiology","raw_type":"journal-article"},{"id":"pmid:2422202","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2422202","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical microbiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:268637","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC268637/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Microbiol","raw_type":"Text"},{"id":"mag:2741953066","doi":null,"is_oa":false,"landing_page_url":"https://jcm.asm.org/content/23/2/333.full.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:268637","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC268637/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Microbiol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5839900691","display_name":"SEXUALLY TRANSMITTED DISEASES RESEARCH CENTER","funder_award_id":"P01AI020110","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W590903312","https://openalex.org/W1483724776","https://openalex.org/W1594824855","https://openalex.org/W1762894351","https://openalex.org/W1855126556","https://openalex.org/W1897660004","https://openalex.org/W1926266423","https://openalex.org/W1942213635","https://openalex.org/W1957261952","https://openalex.org/W1990633912","https://openalex.org/W2030522563","https://openalex.org/W2132228602","https://openalex.org/W2145298013","https://openalex.org/W2168353717"],"related_works":["https://openalex.org/W95416042","https://openalex.org/W1918130674","https://openalex.org/W2128848591","https://openalex.org/W1510753614","https://openalex.org/W7095788419","https://openalex.org/W1923411548","https://openalex.org/W1594824855","https://openalex.org/W2397796589","https://openalex.org/W1984335746","https://openalex.org/W1945589050"],"abstract_inverted_index":{"A":[0],"panel":[1],"of":[2,15,19,53,58,115,138,170],"15":[3,13],"monoclonal":[4,154],"antibodies":[5,21,61,110,155],"was":[6,144],"prepared":[7],"that":[8,79,98,118,130],"could":[9],"distinguish":[10,99],"among":[11],"the":[12,54,59,70,92,100,113,123,131],"serovars":[14,47],"Chlamydia":[16],"trachomatis.":[17],"Twelve":[18],"these":[20,109,150,153],"were":[22,43,62],"specific":[23,44],"for":[24,45,91,168],"a":[25,107,158],"single":[26],"serovar":[27,114],"(A,":[28],"B,":[29],"C,":[30],"D,":[31],"E,":[32],"F,":[33],"G,":[34],"H,":[35],"I,":[36],"K,":[37],"L1,":[38],"and":[39,41,50,56,86,160,166],"L2)":[40],"three":[42],"two":[46,57],"(B/Ba,":[48],"C/J,":[49],"C/L3).":[51],"Ten":[52],"serovar-specific":[55],"bispecific":[60],"shown":[63],"by":[64,96,122],"immunoblotting":[65],"to":[66,146,163],"recognize":[67],"epitopes":[68,81],"on":[69],"major":[71],"outer":[72],"membrane":[73],"protein.":[74],"These":[75],"data":[76],"provide":[77,157],"evidence":[78],"such":[80],"are":[82],"closely":[83],"correlated":[84],"with":[85,149],"may":[87,156],"be":[88],"partly":[89],"responsible":[90],"antigenic":[93],"variations":[94],"detected":[95],"microimmunofluorescence":[97,124,167],"currently":[101],"recognized":[102],"serovars.":[103],"When":[104],"used":[105],"in":[106],"radioimmunoassay,":[108],"correctly":[111],"identified":[112],"17":[116],"strains":[117],"had":[119],"been":[120],"serotyped":[121],"test.":[125],"In":[126],"addition,":[127],"we":[128],"found":[129],"chlamydial":[132],"antigen":[133],"derived":[134],"from":[135],"1.0":[136],"cm2":[137],"an":[139],"infected":[140],"HeLa":[141],"cell":[142],"monolayer":[143],"sufficient":[145],"allow":[147],"serotyping":[148,169],"antibodies.":[151],"Thus,":[152],"rapid":[159],"reliable":[161],"alternative":[162],"mouse":[164],"immunization":[165],"clinical":[171],"isolates.":[172]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}