{"id":"https://openalex.org/W2148705292","doi":"https://doi.org/10.1016/s1470-2045(08)70126-8","title":"Lessons from the skin\u2014cutaneous features of familial cancer","display_name":"Lessons from the skin\u2014cutaneous features of familial cancer","publication_year":2008,"publication_date":"2008-04-29","ids":{"openalex":"https://openalex.org/W2148705292","doi":"https://doi.org/10.1016/s1470-2045(08)70126-8","mag":"2148705292","pmid":"https://pubmed.ncbi.nlm.nih.gov/18452857"},"language":"en","primary_location":{"id":"doi:10.1016/s1470-2045(08)70126-8","doi":"https://doi.org/10.1016/s1470-2045(08)70126-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1470-2045(08)70126-8","pdf_url":null,"source":{"id":"https://openalex.org/S116900674","display_name":"The Lancet Oncology","issn_l":"1470-2045","issn":["1470-2045","1474-5488"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Oncology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076928530","display_name":"Ingrid Winship","orcid":"https://orcid.org/0000-0001-8535-6003","observed_orcids":["https://orcid.org/0000-0001-8535-6003"]},"institutions":[{"id":"https://openalex.org/I1320473756","display_name":"The Royal Melbourne Hospital","ror":"https://ror.org/005bvs909","country_code":"AU","type":"funder","lineage":["https://openalex.org/I1320473756","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Ingrid M Winship","raw_affiliation_strings":["Department of Medicine, University of Melbourne, Royal Melbourne Hospital, VIC, Australia. Ingrid.Winship@mh.org.au","Department of Medicine, University of Melbourne, Royal Melbourne Hospital, VIC, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Melbourne, Royal Melbourne Hospital, VIC, Australia. Ingrid.Winship@mh.org.au","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I165779595"]},{"raw_affiliation_string":"Department of Medicine, University of Melbourne, Royal Melbourne Hospital, VIC, Australia","institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I165779595"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110118883","display_name":"Tracy E Dudding","orcid":"https://orcid.org/0000-0002-9551-1107","observed_orcids":["https://orcid.org/0000-0002-9551-1107"]},"institutions":[{"id":"https://openalex.org/I78757542","display_name":"University of Newcastle Australia","ror":"https://ror.org/00eae9z71","country_code":"AU","type":"education","lineage":["https://openalex.org/I78757542"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Tracy E Dudding","raw_affiliation_strings":["Hunter Family Cancer Service, Hunter Area Health Service, Newcastle, NSW and University of Newcastle, Newcastle, NSW, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hunter Family Cancer Service, Hunter Area Health Service, Newcastle, NSW and University of Newcastle, Newcastle, NSW, Australia","institution_ids":["https://openalex.org/I78757542"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5076928530"],"corresponding_institution_ids":["https://openalex.org/I1320473756","https://openalex.org/I165779595"],"apc_list":{"value":7280,"currency":"USD","value_usd":7280},"apc_paid":null,"fwci":0.7807,"has_fulltext":false,"cited_by_count":54,"citation_normalized_percentile":{"value":0.5989071,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"9","issue":"5","first_page":"462","last_page":"472"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.43209999799728394,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.43209999799728394,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.3732999861240387,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12355","display_name":"Genetic and rare skin diseases.","score":0.1177000030875206,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hereditary-cancer-syndromes","display_name":"hereditary cancer","score":0.9100000262260437},{"id":"https://openalex.org/keywords/cutaneous-manifestations","display_name":"cutaneous manifestations","score":0.8169999718666077},{"id":"https://openalex.org/keywords/hereditary-breast-and-ovarian-cancer-syndrome","display_name":"hereditary breast and ovarian cancer","score":0.7990000247955322},{"id":"https://openalex.org/keywords/brca-mutations","display_name":"BRCA mutations","score":0.8880000114440918},{"id":"https://openalex.org/keywords/hereditary-non-polyposis-colon-cancer","display_name":"hereditary non-polyposis colon cancer","score":0.9660000205039978},{"id":"https://openalex.org/keywords/familial-adenomatous-polyposis","display_name":"familial adenomatous polyposis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/high-risk-features","display_name":"high-risk features","score":0.40400001406669617}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7851332426071167},{"id":"https://openalex.org/C2780814781","wikidata":"https://www.wikidata.org/wiki/Q1369011","display_name":"Familial adenomatous polyposis","level":4,"score":0.766027569770813},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.6732308864593506},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.673107922077179},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.6241123080253601},{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.568037211894989},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5604948401451111},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.48072245717048645},{"id":"https://openalex.org/C2780194787","wikidata":"https://www.wikidata.org/wiki/Q4836333","display_name":"BRCA mutation","level":4,"score":0.4399207532405853},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.43772798776626587},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.43644633889198303},{"id":"https://openalex.org/C67636389","wikidata":"https://www.wikidata.org/wiki/Q784237","display_name":"Genetic predisposition","level":3,"score":0.4257115423679352},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40539610385894775},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32742610573768616},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.3033050298690796},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16363704204559326},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07525479793548584},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07511231303215027}],"mesh":[{"descriptor_ui":"D001478","descriptor_name":"Basal Cell Nevus Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002292","descriptor_name":"Carcinoma, Renal Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D003123","descriptor_name":"Colorectal Neoplasms, Hereditary Nonpolyposis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004701","descriptor_name":"Endocrine Gland Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004701","descriptor_name":"Endocrine Gland Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006223","descriptor_name":"Hamartoma Syndrome, Multiple","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007680","descriptor_name":"Kidney Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007680","descriptor_name":"Kidney Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009377","descriptor_name":"Multiple Endocrine Neoplasia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009386","descriptor_name":"Neoplastic Syndromes, Hereditary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009386","descriptor_name":"Neoplastic Syndromes, Hereditary","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D009456","descriptor_name":"Neurofibromatosis 1","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010580","descriptor_name":"Peutz-Jeghers Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011125","descriptor_name":"Adenomatous Polyposis Coli","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012867","descriptor_name":"Skin","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014402","descriptor_name":"Tuberous Sclerosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016518","descriptor_name":"Neurofibromatosis 2","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018231","descriptor_name":"Leiomyomatosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018813","descriptor_name":"Multiple Endocrine Neoplasia Type 2a","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018814","descriptor_name":"Multiple Endocrine Neoplasia Type 2b","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/s1470-2045(08)70126-8","doi":"https://doi.org/10.1016/s1470-2045(08)70126-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1470-2045(08)70126-8","pdf_url":null,"source":{"id":"https://openalex.org/S116900674","display_name":"The Lancet Oncology","issn_l":"1470-2045","issn":["1470-2045","1474-5488"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet Oncology","raw_type":"journal-article"},{"id":"pmid:18452857","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18452857","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Lancet. Oncology","raw_type":"Journal Article"},{"id":"pmh:uon:4697","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/1959.13/41261","pdf_url":null,"source":{"id":"https://openalex.org/S4377196471","display_name":"NOVA (University of Newcastle Australia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I78757542","host_organization_name":"University of Newcastle Australia","host_organization_lineage":["https://openalex.org/I78757542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"mag:3025499872","doi":null,"is_oa":false,"landing_page_url":"https://findanexpert.unimelb.edu.au/scholarlywork/299615-lessons-from-the-skin---cutaneous-features-of-familial-cancer","pdf_url":null,"source":{"id":"https://openalex.org/S49861241","display_name":"The Lancet","issn_l":"0099-5355","issn":["0099-5355","0140-6736","1474-547X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"The Lancet","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W107359358","https://openalex.org/W180964678","https://openalex.org/W1526007030","https://openalex.org/W1842830342","https://openalex.org/W1964948442","https://openalex.org/W1967291345","https://openalex.org/W1972730151","https://openalex.org/W1981524857","https://openalex.org/W1988768298","https://openalex.org/W1990143243","https://openalex.org/W2003878665","https://openalex.org/W2012045377","https://openalex.org/W2012589790","https://openalex.org/W2017309361","https://openalex.org/W2022132548","https://openalex.org/W2022148326","https://openalex.org/W2022667011","https://openalex.org/W2025500668","https://openalex.org/W2027772907","https://openalex.org/W2027806031","https://openalex.org/W2029076196","https://openalex.org/W2029843397","https://openalex.org/W2035079060","https://openalex.org/W2035826141","https://openalex.org/W2047597784","https://openalex.org/W2047641374","https://openalex.org/W2049727086","https://openalex.org/W2050650475","https://openalex.org/W2051086393","https://openalex.org/W2052498320","https://openalex.org/W2053409049","https://openalex.org/W2055624543","https://openalex.org/W2063416195","https://openalex.org/W2064533401","https://openalex.org/W2066465360","https://openalex.org/W2068892354","https://openalex.org/W2070519709","https://openalex.org/W2071228044","https://openalex.org/W2072011119","https://openalex.org/W2074147961","https://openalex.org/W2086934839","https://openalex.org/W2088104961","https://openalex.org/W2091798264","https://openalex.org/W2092864149","https://openalex.org/W2094659848","https://openalex.org/W2095115908","https://openalex.org/W2096371251","https://openalex.org/W2096393537","https://openalex.org/W2099513664","https://openalex.org/W2105256330","https://openalex.org/W2106039705","https://openalex.org/W2110394707","https://openalex.org/W2122230708","https://openalex.org/W2125955965","https://openalex.org/W2126222796","https://openalex.org/W2128793721","https://openalex.org/W2130251781","https://openalex.org/W2135230791","https://openalex.org/W2137304051","https://openalex.org/W2139654861","https://openalex.org/W2140937522","https://openalex.org/W2141278789","https://openalex.org/W2141765134","https://openalex.org/W2145035596","https://openalex.org/W2146322961","https://openalex.org/W2146718153","https://openalex.org/W2150499124","https://openalex.org/W2157450466","https://openalex.org/W2158107502","https://openalex.org/W2163614715","https://openalex.org/W2169619819","https://openalex.org/W2383259826","https://openalex.org/W2414688077","https://openalex.org/W2418506899","https://openalex.org/W4211222004","https://openalex.org/W6680914424"],"related_works":["https://openalex.org/W4396687634","https://openalex.org/W2158107502","https://openalex.org/W2125875796","https://openalex.org/W3014759467","https://openalex.org/W4211133738","https://openalex.org/W1765288701","https://openalex.org/W3175774932","https://openalex.org/W4411670698","https://openalex.org/W3005520907","https://openalex.org/W654938491"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}