{"id":"https://openalex.org/W2148246325","doi":"https://doi.org/10.1002/elps.200405895","title":"Recent developments in the determination of urinary cancer biomarkers by capillary electrophoresis","display_name":"Recent developments in the determination of urinary cancer biomarkers by capillary electrophoresis","publication_year":2004,"publication_date":"2004-06-01","ids":{"openalex":"https://openalex.org/W2148246325","doi":"https://doi.org/10.1002/elps.200405895","mag":"2148246325","pmid":"https://pubmed.ncbi.nlm.nih.gov/15188229"},"language":"en","primary_location":{"id":"doi:10.1002/elps.200405895","doi":"https://doi.org/10.1002/elps.200405895","is_oa":false,"landing_page_url":"https://doi.org/10.1002/elps.200405895","pdf_url":null,"source":{"id":"https://openalex.org/S2849398","display_name":"Electrophoresis","issn_l":"0173-0835","issn":["0173-0835","1522-2683"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ELECTROPHORESIS","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081352482","display_name":"Yinfa Ma","orcid":"https://orcid.org/0000-0002-9719-8345","observed_orcids":["https://orcid.org/0000-0002-9719-8345"]},"institutions":[{"id":"https://openalex.org/I20382870","display_name":"Missouri University of Science and Technology","ror":"https://ror.org/00scwqd12","country_code":"US","type":"education","lineage":["https://openalex.org/I20382870"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Yinfa Ma","raw_affiliation_strings":["Department of Chemistry, University of Missouri-Rolla, 1870 Miner Circle, Rolla, MO 65409, USA. yinfa@umr.edu","Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Missouri-Rolla, 1870 Miner Circle, Rolla, MO 65409, USA. yinfa@umr.edu","institution_ids":["https://openalex.org/I20382870"]},{"raw_affiliation_string":"Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA","institution_ids":["https://openalex.org/I20382870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048398648","display_name":"Guanshu Liu","orcid":"https://orcid.org/0000-0002-8188-4332","observed_orcids":["https://orcid.org/0000-0002-8188-4332","https://orcid.org/0009-0002-4556-2923"]},"institutions":[{"id":"https://openalex.org/I20382870","display_name":"Missouri University of Science and Technology","ror":"https://ror.org/00scwqd12","country_code":"US","type":"education","lineage":["https://openalex.org/I20382870"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guanshu Liu","raw_affiliation_strings":["Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA","institution_ids":["https://openalex.org/I20382870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110211417","display_name":"Ming Rui Du","orcid":"https://orcid.org/0000-0003-4886-1398","observed_orcids":["https://orcid.org/0000-0003-4886-1398"]},"institutions":[{"id":"https://openalex.org/I20382870","display_name":"Missouri University of Science and Technology","ror":"https://ror.org/00scwqd12","country_code":"US","type":"education","lineage":["https://openalex.org/I20382870"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ming Du","raw_affiliation_strings":["Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA","institution_ids":["https://openalex.org/I20382870"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026744329","display_name":"Isaac Stayton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I20382870","display_name":"Missouri University of Science and Technology","ror":"https://ror.org/00scwqd12","country_code":"US","type":"education","lineage":["https://openalex.org/I20382870"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Isaac Stayton","raw_affiliation_strings":["Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Missouri-Rolla, Rolla, MO, USA","institution_ids":["https://openalex.org/I20382870"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5081352482"],"corresponding_institution_ids":["https://openalex.org/I20382870"],"apc_list":{"value":3940,"currency":"USD","value_usd":3940},"apc_paid":null,"fwci":0.5133,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.45,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"25","issue":"10-11","first_page":"1473","last_page":"1484"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.9833999872207642,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/capillary-electrophoresis","display_name":"capillary electrophoresis","score":0.9829999804496765},{"id":"https://openalex.org/keywords/cancer-diagnosis","display_name":"cancer diagnosis","score":0.7319999933242798},{"id":"https://openalex.org/keywords/urine-analysis","display_name":"urine analysis","score":0.6340000033378601},{"id":"https://openalex.org/keywords/biomarker-detection","display_name":"biomarker detection","score":0.5109999775886536},{"id":"https://openalex.org/keywords/treatment-follow-up","display_name":"treatment follow-up","score":0.5450000166893005}],"concepts":[{"id":"https://openalex.org/C2900643","wikidata":"https://www.wikidata.org/wiki/Q747468","display_name":"Capillary electrophoresis","level":2,"score":0.7200636267662048},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.668521523475647},{"id":"https://openalex.org/C2777002142","wikidata":"https://www.wikidata.org/wiki/Q5031432","display_name":"Cancer biomarkers","level":3,"score":0.6557133197784424},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.604637622833252},{"id":"https://openalex.org/C3020728648","wikidata":"https://www.wikidata.org/wiki/Q1058795","display_name":"Biological fluids","level":2,"score":0.5475576519966125},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.4855630099773407},{"id":"https://openalex.org/C2985322473","wikidata":"https://www.wikidata.org/wiki/Q3044843","display_name":"Cancer detection","level":3,"score":0.4759533107280731},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40816134214401245},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27448374032974243},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.20575562119483948},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1650998294353485},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10154971480369568},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D001798","descriptor_name":"Blood Proteins","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009705","descriptor_name":"Nucleosides","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D009705","descriptor_name":"Nucleosides","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D010266","descriptor_name":"Paraproteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D010266","descriptor_name":"Paraproteins","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D011509","descriptor_name":"Proteoglycans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D019032","descriptor_name":"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019075","descriptor_name":"Electrophoresis, Capillary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019158","descriptor_name":"N-Acetylneuraminic Acid","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D019158","descriptor_name":"N-Acetylneuraminic Acid","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/elps.200405895","doi":"https://doi.org/10.1002/elps.200405895","is_oa":false,"landing_page_url":"https://doi.org/10.1002/elps.200405895","pdf_url":null,"source":{"id":"https://openalex.org/S2849398","display_name":"Electrophoresis","issn_l":"0173-0835","issn":["0173-0835","1522-2683"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ELECTROPHORESIS","raw_type":"journal-article"},{"id":"pmid:15188229","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15188229","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Electrophoresis","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8999999761581421}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7099999785423279}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":148,"referenced_works":["https://openalex.org/W12877732","https://openalex.org/W36874382","https://openalex.org/W95293157","https://openalex.org/W96723445","https://openalex.org/W847987053","https://openalex.org/W1480262145","https://openalex.org/W1498039710","https://openalex.org/W1592068735","https://openalex.org/W1604887751","https://openalex.org/W1783564941","https://openalex.org/W1786785042","https://openalex.org/W1963798117","https://openalex.org/W1964196877","https://openalex.org/W1964537258","https://openalex.org/W1964684239","https://openalex.org/W1971944970","https://openalex.org/W1973803357","https://openalex.org/W1974898170","https://openalex.org/W1975207356","https://openalex.org/W1976685869","https://openalex.org/W1979411975","https://openalex.org/W1982071962","https://openalex.org/W1982615224","https://openalex.org/W1984486439","https://openalex.org/W1988393167","https://openalex.org/W1990599092","https://openalex.org/W1991919065","https://openalex.org/W1992478180","https://openalex.org/W1992849488","https://openalex.org/W1993630612","https://openalex.org/W1995096144","https://openalex.org/W1996278766","https://openalex.org/W1997081866","https://openalex.org/W1997603970","https://openalex.org/W1999797596","https://openalex.org/W1999932025","https://openalex.org/W2000982990","https://openalex.org/W2004980463","https://openalex.org/W2006713328","https://openalex.org/W2007928412","https://openalex.org/W2008662636","https://openalex.org/W2010597170","https://openalex.org/W2012146322","https://openalex.org/W2014290450","https://openalex.org/W2015041290","https://openalex.org/W2015086264","https://openalex.org/W2015450806","https://openalex.org/W2015750060","https://openalex.org/W2015835663","https://openalex.org/W2016522356","https://openalex.org/W2018185503","https://openalex.org/W2021024479","https://openalex.org/W2022226171","https://openalex.org/W2023195919","https://openalex.org/W2023677185","https://openalex.org/W2023693885","https://openalex.org/W2025012932","https://openalex.org/W2025476105","https://openalex.org/W2025737481","https://openalex.org/W2028593001","https://openalex.org/W2029400956","https://openalex.org/W2030172614","https://openalex.org/W2031068201","https://openalex.org/W2031362600","https://openalex.org/W2032162581","https://openalex.org/W2032900871","https://openalex.org/W2035744980","https://openalex.org/W2035783776","https://openalex.org/W2036423499","https://openalex.org/W2036761507","https://openalex.org/W2040260922","https://openalex.org/W2040981588","https://openalex.org/W2042361152","https://openalex.org/W2042793179","https://openalex.org/W2044233840","https://openalex.org/W2045072343","https://openalex.org/W2045201098","https://openalex.org/W2045791479","https://openalex.org/W2047275057","https://openalex.org/W2047664661","https://openalex.org/W2052034749","https://openalex.org/W2052641311","https://openalex.org/W2056101504","https://openalex.org/W2058058619","https://openalex.org/W2058469779","https://openalex.org/W2059191790","https://openalex.org/W2060054628","https://openalex.org/W2062046899","https://openalex.org/W2062486292","https://openalex.org/W2062531327","https://openalex.org/W2062636111","https://openalex.org/W2062750886","https://openalex.org/W2063356186","https://openalex.org/W2065892156","https://openalex.org/W2067367612","https://openalex.org/W2067623537","https://openalex.org/W2069736425","https://openalex.org/W2072338350","https://openalex.org/W2075390921","https://openalex.org/W2079295289","https://openalex.org/W2080657413","https://openalex.org/W2084714412","https://openalex.org/W2086055500","https://openalex.org/W2087172982","https://openalex.org/W2087602327","https://openalex.org/W2088179131","https://openalex.org/W2089160912","https://openalex.org/W2090892746","https://openalex.org/W2091516579","https://openalex.org/W2092283834","https://openalex.org/W2093377677","https://openalex.org/W2093913553","https://openalex.org/W2097687472","https://openalex.org/W2099960600","https://openalex.org/W2102461055","https://openalex.org/W2102701083","https://openalex.org/W2106207977","https://openalex.org/W2108807647","https://openalex.org/W2118715957","https://openalex.org/W2124516940","https://openalex.org/W2124758454","https://openalex.org/W2126477970","https://openalex.org/W2127106696","https://openalex.org/W2133160676","https://openalex.org/W2133893372","https://openalex.org/W2134389439","https://openalex.org/W2134871916","https://openalex.org/W2138165179","https://openalex.org/W2141206067","https://openalex.org/W2143909801","https://openalex.org/W2149024868","https://openalex.org/W2149371634","https://openalex.org/W2153216678","https://openalex.org/W2158023865","https://openalex.org/W2162906563","https://openalex.org/W2163838141","https://openalex.org/W2168817111","https://openalex.org/W2172300860","https://openalex.org/W2207781361","https://openalex.org/W2279579902","https://openalex.org/W2293485376","https://openalex.org/W2313636238","https://openalex.org/W2334544196","https://openalex.org/W2433588899","https://openalex.org/W4211166883","https://openalex.org/W4238270754","https://openalex.org/W4252094383","https://openalex.org/W4302091583"],"related_works":["https://openalex.org/W1994505162","https://openalex.org/W2086098303","https://openalex.org/W638059997","https://openalex.org/W2126443487","https://openalex.org/W4281493265","https://openalex.org/W2102598214","https://openalex.org/W2044381912","https://openalex.org/W2960634752","https://openalex.org/W2110968459","https://openalex.org/W2084925449"],"abstract_inverted_index":{"Investigation":[0],"of":[1,11,41,51,115,134,169],"effective":[2],"biomarkers":[3,160],"for":[4],"cancers":[5],"is":[6,122],"currently":[7],"a":[8,126,167],"popular":[9],"area":[10],"study":[12,114],"in":[13,71,113],"clinical":[14],"and":[15,29,37,44,59,76,100,129,140,161,174],"cancer":[16,35,72,77,82,116],"researches,":[17,73],"because":[18,133],"it":[19],"can":[20],"potentially":[21],"lead":[22],"to":[23,65,124,150],"pre-cancer":[24,27,74],"screening":[25],"or":[26,47,80],"diagnosis":[28],"may":[30],"provide":[31],"useful":[32,70],"information":[33],"on":[34],"type":[36],"the":[38,52,135,156],"disease's":[39],"stage":[40],"progression.":[42],"More":[43],"more":[45],"biochemical":[46],"chemical":[48],"fluid":[49,61],"components":[50],"human":[53],"body":[54],"such":[55,88],"as":[56,89,104,106],"urine,":[57],"blood,":[58],"cerebrospinal":[60],"have":[62,109],"been":[63,110],"considered":[64,123],"contain":[66],"biomarkers,":[67],"which":[68],"are":[69],"diagnosis,":[75],"follow-ups":[78],"during":[79],"after":[81],"treatment.":[83],"Several":[84],"modern":[85],"analytical":[86,131],"techniques,":[87,108,120],"gas":[90],"chromatography":[91,95],"(GC),":[92],"high-performance":[93],"liquid":[94],"(HPLC),":[96],"capillary":[97],"electrophoresis":[98],"(CE),":[99],"other":[101],"separation":[102,143],"techniques":[103],"well":[105],"hyphenated":[107],"extensively":[111],"used":[112],"biomarkers.":[117],"Among":[118],"these":[119],"CE":[121],"be":[125],"highly":[127],"efficient":[128],"practical":[130],"technique":[132],"small":[136,147],"sample":[137],"volume":[138],"requirement":[139],"its":[141],"wide":[142],"versatility,":[144],"ranging":[145],"from":[146],"inorganic":[148],"molecules":[149],"large":[151],"biomolecules.":[152],"This":[153],"review":[154],"discusses":[155],"latest":[157],"developments":[158],"involving":[159],"their":[162],"analysis":[163],"by":[164],"CE,":[165],"including":[166],"discussion":[168],"instrumental":[170],"conditions,":[171],"method":[172],"developments,":[173],"data":[175],"analysis.":[176]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}