{"id":"https://openalex.org/W2148158451","doi":"https://doi.org/10.1111/ggi.12334","title":"Personal mastery, multisystem physiological dysregulation and risk of functional decline in older adults: A prospective study in T aiwan","display_name":"Personal mastery, multisystem physiological dysregulation and risk of functional decline in older adults: A prospective study in T aiwan","publication_year":2014,"publication_date":"2014-08-11","ids":{"openalex":"https://openalex.org/W2148158451","doi":"https://doi.org/10.1111/ggi.12334","mag":"2148158451","pmid":"https://pubmed.ncbi.nlm.nih.gov/25109374"},"language":"en","primary_location":{"id":"doi:10.1111/ggi.12334","doi":"https://doi.org/10.1111/ggi.12334","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ggi.12334","pdf_url":null,"source":{"id":"https://openalex.org/S88760654","display_name":"Geriatrics and gerontology international/Geriatrics & gerontology international","issn_l":"1444-1586","issn":["1444-1586","1447-0594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Geriatrics & Gerontology International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020929536","display_name":"I\u2010Chien Wu","orcid":"https://orcid.org/0000-0002-6916-8165","observed_orcids":["https://orcid.org/0000-0002-6916-8165"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"I\u2010Chien Wu","raw_affiliation_strings":["Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan","Program for Aging, College of Medicine, China Medical University, Taichung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan","institution_ids":["https://openalex.org/I165441096"]},{"raw_affiliation_string":"Program for Aging, College of Medicine, China Medical University, Taichung, Taiwan","institution_ids":["https://openalex.org/I184693016"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016184067","display_name":"Chao Agnes Hsiung","orcid":"https://orcid.org/0000-0003-1427-6641","observed_orcids":["https://orcid.org/0000-0003-1427-6641"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chao A Hsiung","raw_affiliation_strings":["Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004688940","display_name":"I\u2010Shou Chang","orcid":"https://orcid.org/0000-0002-6254-8114","observed_orcids":["https://orcid.org/0000-0002-6254-8114"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"I\u2010Shou Chang","raw_affiliation_strings":["Institute of Cancer Research and Division of Biostatistics and Bioinformatics, National Health Research Institutes, Miaoli County, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cancer Research and Division of Biostatistics and Bioinformatics, National Health Research Institutes, Miaoli County, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044827208","display_name":"Ming\u2010Shiang Wu","orcid":"https://orcid.org/0000-0002-1940-6428","observed_orcids":["https://orcid.org/0000-0002-1940-6428","https://orcid.org/0000-0002-0800-5506"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Ming\u2010Shiang Wu","raw_affiliation_strings":["Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042707313","display_name":"Yu\u2010Hung Chang","orcid":"https://orcid.org/0000-0003-1484-4960","observed_orcids":["https://orcid.org/0000-0003-1484-4960"]},"institutions":[{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yu\u2010Hung Chang","raw_affiliation_strings":["Department of Public Health, China Medical University, Taichung, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health, China Medical University, Taichung, Taiwan","institution_ids":["https://openalex.org/I184693016"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112260516","display_name":"Chih\u2010Cheng Hsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]},{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]},{"id":"https://openalex.org/I4210126829","display_name":"China Medical University Hospital","ror":"https://ror.org/0368s4g32","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I4210126829"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Chih\u2010Cheng Hsu","raw_affiliation_strings":["Department of Health Services Administration, China Medical University and Hospital, Taichung, Taiwan","Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Services Administration, China Medical University and Hospital, Taichung, Taiwan","institution_ids":["https://openalex.org/I184693016","https://openalex.org/I4210126829"]},{"raw_affiliation_string":"Institute of Population Health Sciences, National Health Research Institutes, Miaoli County, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5112260516"],"corresponding_institution_ids":["https://openalex.org/I165441096","https://openalex.org/I184693016","https://openalex.org/I4210126829"],"apc_list":{"value":3750,"currency":"USD","value_usd":3750},"apc_paid":null,"fwci":0.6465,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.76250385,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"15","issue":"6","first_page":"707","last_page":"714"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12811","display_name":"Aging, Health, and Disability","score":0.5570999979972839,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12811","display_name":"Aging, Health, and Disability","score":0.5570999979972839,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11265","display_name":"Aging and Gerontology Research","score":0.18240000307559967,"subfield":{"id":"https://openalex.org/subfields/3204","display_name":"Developmental and Educational Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.09759999811649323,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/personal-mastery","display_name":"personal mastery","score":0.9959999918937683},{"id":"https://openalex.org/keywords/functional-decline","display_name":"functional decline","score":0.7900000214576721},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9259999990463257},{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9369999766349792},{"id":"https://openalex.org/keywords/aging-biomarkers","display_name":"aging biomarkers","score":0.7739999890327454},{"id":"https://openalex.org/keywords/activities-of-daily-living","display_name":"activities of daily living","score":0.972000002861023},{"id":"https://openalex.org/keywords/asian-populations","display_name":"Asian populations","score":0.4180000126361847}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6693090796470642},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5709762573242188},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5511721968650818},{"id":"https://openalex.org/C68443243","wikidata":"https://www.wikidata.org/wiki/Q2786686","display_name":"Quartile","level":3,"score":0.5253581404685974},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.47274860739707947},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.4508022964000702},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4198583960533142},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36518052220344543},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.36303824186325073},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3443741202354431},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.12940850853919983},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000203","descriptor_name":"Activities of Daily Living","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004185","descriptor_name":"Disability Evaluation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006233","descriptor_name":"Persons with Disabilities","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013624","descriptor_name":"Taiwan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015577","descriptor_name":"Geriatric Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016330","descriptor_name":"Frail Elderly","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026684","descriptor_name":"Personal Autonomy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051346","descriptor_name":"Mobility Limitation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/ggi.12334","doi":"https://doi.org/10.1111/ggi.12334","is_oa":false,"landing_page_url":"https://doi.org/10.1111/ggi.12334","pdf_url":null,"source":{"id":"https://openalex.org/S88760654","display_name":"Geriatrics and gerontology international/Geriatrics & gerontology international","issn_l":"1444-1586","issn":["1444-1586","1447-0594"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Geriatrics & Gerontology International","raw_type":"journal-article"},{"id":"pmid:25109374","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25109374","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Geriatrics & gerontology international","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G7305849603","display_name":"Biodemography of Health, Social Factors and Life Challenge","funder_award_id":"R01AG016790","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G7651113465","display_name":"Biodemography of Health, Social Factors & Life Challenge","funder_award_id":"R01AG016661","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"}],"funders":[{"id":"https://openalex.org/F4320322845","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29"},{"id":"https://openalex.org/F4320333462","display_name":"Health Promotion Administration, Ministry of Health and Welfare","ror":null},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W142363866","https://openalex.org/W1544215667","https://openalex.org/W1999982075","https://openalex.org/W2008752952","https://openalex.org/W2015252215","https://openalex.org/W2023181503","https://openalex.org/W2039022968","https://openalex.org/W2048543091","https://openalex.org/W2052143620","https://openalex.org/W2058312082","https://openalex.org/W2074833591","https://openalex.org/W2078367877","https://openalex.org/W2080383392","https://openalex.org/W2089134353","https://openalex.org/W2100487394","https://openalex.org/W2105515466","https://openalex.org/W2107466701","https://openalex.org/W2109215792","https://openalex.org/W2124376043","https://openalex.org/W2129390990","https://openalex.org/W2143688594","https://openalex.org/W2145796291","https://openalex.org/W2155766766","https://openalex.org/W2158426152","https://openalex.org/W2316138036","https://openalex.org/W2586645431","https://openalex.org/W4292480755","https://openalex.org/W4293179688","https://openalex.org/W4294185218"],"related_works":["https://openalex.org/W4389508968","https://openalex.org/W2512780817","https://openalex.org/W1544215667","https://openalex.org/W2087364783","https://openalex.org/W4281747303","https://openalex.org/W2078367877","https://openalex.org/W2340580867","https://openalex.org/W2153746454","https://openalex.org/W2778148318","https://openalex.org/W4402060155"],"abstract_inverted_index":{"AIM:":[0],"Personal":[1],"mastery":[2,23,64,132,164,181,215,225],"has":[3],"been":[4],"associated":[5,167,183,228],"with":[6,151,168,184,229],"physical":[7],"function":[8],"maintenance":[9],"later":[10],"in":[11,27,57,108,125,143,236],"life.":[12],"Less":[13],"is":[14,226],"known":[15],"about":[16],"the":[17,44,66,83,89,92,96,99,103,126,130,144,149,196,204,207],"relationship":[18],"between":[19,209],"lack":[20],"of":[21,49,62,85,88,110,129,179,198,213,223,233],"personal":[22,63,131,163,180,214,224],"and":[24,30,47,102,117,216],"functional":[25,139,169,217,234],"decline":[26,140,218,235],"Asian":[28],"populations,":[29],"whether":[31],"multisystem":[32,187],"physiological":[33,71,188,199,240],"dysregulation":[34,72,189,200,241],"explains":[35,243],"this":[36,244],"relationship.":[37,245],"METHODS:":[38],"Participants":[39,124],"(n":[40],"=":[41,193],"487)":[42],"from":[43],"Social":[45],"Environment":[46],"Biomarkers":[48],"Aging":[50],"Study,":[51],"a":[52,78,119,210],"population-based":[53],"prospective":[54],"cohort":[55],"study":[56],"Taiwan,":[58],"received":[59],"baseline":[60,74,116],"measurements":[61],"using":[65],"Pearlin":[67],"Mastery":[68],"Scale.":[69],"Multisystem":[70,239],"at":[73,115,118],"was":[75,113,182,219],"assessed":[76],"as":[77],"summary":[79],"score":[80,133],"based":[81],"on":[82],"levels":[84,197],"16":[86],"biomarkers":[87],"hypothalamic-pituitary-adrenal":[90],"axis,":[91],"sympathetic":[93],"nervous":[94],"system,":[95,98],"cardiovascular":[97],"metabolic":[100],"system":[101,105],"immune":[104],"functioning.":[106],"Function":[107],"activities":[109],"daily":[111],"living":[112],"determined":[114],"7-year":[120],"follow":[121],"up.":[122],"RESULTS:":[123],"lowest":[127,150],"quartile":[128],"were":[134,201],"more":[135],"likely":[136],"to":[137,203],"experience":[138],"than":[141],"those":[142],"higher":[145],"quartiles":[146,154],"(OR":[147],"comparing":[148],"highest":[152],"3":[153],"2.99,":[155],"95%":[156,174],"CI":[157,175],"1.71-5.21).":[158],"After":[159],"adjusting":[160],"for":[161,191],"confounders,":[162],"remained":[165],"significantly":[166,185],"changes":[170],"(adjusted":[171],"OR":[172],"2.09,":[173],"1.05-4.14).":[176],"Greater":[177],"sense":[178,212],"less":[186],"(P":[190],"trend":[192],"0.001).":[194],"When":[195],"added":[202],"multivariate":[205],"models,":[206],"association":[208],"poor":[211],"attenuated.":[220],"CONCLUSIONS:":[221],"Lack":[222],"independently":[227],"an":[230],"increased":[231],"risk":[232],"older":[237],"adults.":[238],"partially":[242]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2016,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}