{"id":"https://openalex.org/W2148069787","doi":"https://doi.org/10.1098/rsif.2011.0691","title":"Impact of release dynamics of laser-irradiated polymer micropallets on the viability of selected adherent cells","display_name":"Impact of release dynamics of laser-irradiated polymer micropallets on the viability of selected adherent cells","publication_year":2011,"publication_date":"2011-12-07","ids":{"openalex":"https://openalex.org/W2148069787","doi":"https://doi.org/10.1098/rsif.2011.0691","mag":"2148069787","pmid":"https://pubmed.ncbi.nlm.nih.gov/22158840","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3350736"},"language":"en","primary_location":{"id":"doi:10.1098/rsif.2011.0691","doi":"https://doi.org/10.1098/rsif.2011.0691","is_oa":false,"landing_page_url":"https://doi.org/10.1098/rsif.2011.0691","pdf_url":null,"source":{"id":"https://openalex.org/S129150467","display_name":"Journal of The Royal Society Interface","issn_l":"1742-5662","issn":["1742-5662","1742-5689"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of The Royal Society Interface","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3350736","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Huan Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]},{"id":"https://openalex.org/I4210133819","display_name":"Beckman Laser Institute and Medical Clinic","ror":"https://ror.org/03bfp2076","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133819"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huan Ma","raw_affiliation_strings":["1","2","Department\u00a0of Chemical Engineering and Materials Science, University of California, 916 Engineering Tower, Irvine, CA 92697-2575, USA","Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92697-1475, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1","institution_ids":[]},{"raw_affiliation_string":"2","institution_ids":[]},{"raw_affiliation_string":"Department\u00a0of Chemical Engineering and Materials Science, University of California, 916 Engineering Tower, Irvine, CA 92697-2575, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92697-1475, USA","institution_ids":["https://openalex.org/I204250578","https://openalex.org/I4210133819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057447413","display_name":"Wael Mismar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]},{"id":"https://openalex.org/I4210133819","display_name":"Beckman Laser Institute and Medical Clinic","ror":"https://ror.org/03bfp2076","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133819"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wael Mismar","raw_affiliation_strings":["2","3","Department\u00a0of Biomedical Engineering, University of California, Irvine, CA 92697-2715, USA","Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92697-1475, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2","institution_ids":[]},{"raw_affiliation_string":"3","institution_ids":[]},{"raw_affiliation_string":"Department\u00a0of Biomedical Engineering, University of California, Irvine, CA 92697-2715, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92697-1475, USA","institution_ids":["https://openalex.org/I204250578","https://openalex.org/I4210133819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100741506","display_name":"Yuli Wang","orcid":"https://orcid.org/0000-0002-5500-3351","observed_orcids":["https://orcid.org/0000-0002-5500-3351"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuli Wang","raw_affiliation_strings":["4","Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077501399","display_name":"Donald W. Small","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140234","display_name":"LightWorks (United States)","ror":"https://ror.org/03st6mq49","country_code":"US","type":"company","lineage":["https://openalex.org/I4210140234"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald W. Small","raw_affiliation_strings":["5","LightWorks Optics, 14192 Chambers Road, Tustin, CA 92780-6910, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5","institution_ids":[]},{"raw_affiliation_string":"LightWorks Optics, 14192 Chambers Road, Tustin, CA 92780-6910, USA","institution_ids":["https://openalex.org/I4210140234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030874423","display_name":"M. C. D. Ras","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140234","display_name":"LightWorks (United States)","ror":"https://ror.org/03st6mq49","country_code":"US","type":"company","lineage":["https://openalex.org/I4210140234"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mat Ras","raw_affiliation_strings":["5","LightWorks Optics, 14192 Chambers Road, Tustin, CA 92780-6910, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5","institution_ids":[]},{"raw_affiliation_string":"LightWorks Optics, 14192 Chambers Road, Tustin, CA 92780-6910, USA","institution_ids":["https://openalex.org/I4210140234"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048509828","display_name":"Nancy L. Allbritton","orcid":"https://orcid.org/0000-0002-9242-768X","observed_orcids":["https://orcid.org/0000-0002-9242-768X"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy L. Allbritton","raw_affiliation_strings":["4","Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084492610","display_name":"Christopher E. Sims","orcid":"https://orcid.org/0000-0001-9991-3317","observed_orcids":["https://orcid.org/0000-0001-9991-3317"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher E. Sims","raw_affiliation_strings":["4","Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4","institution_ids":[]},{"raw_affiliation_string":"Department of Chemistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3290, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083213372","display_name":"Vasan Venugopalan","orcid":"https://orcid.org/0000-0003-4781-1049","observed_orcids":["https://orcid.org/0000-0003-4781-1049"]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]},{"id":"https://openalex.org/I4210133819","display_name":"Beckman Laser Institute and Medical Clinic","ror":"https://ror.org/03bfp2076","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210133819"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Vasan Venugopalan","raw_affiliation_strings":["1","2","3","Department\u00a0of Biomedical Engineering, University of California, Irvine, CA 92697-2715, USA","Department\u00a0of Chemical Engineering and Materials Science, University of California, 916 Engineering Tower, Irvine, CA 92697-2575, USA","Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92697-1475, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1","institution_ids":[]},{"raw_affiliation_string":"2","institution_ids":[]},{"raw_affiliation_string":"3","institution_ids":[]},{"raw_affiliation_string":"Department\u00a0of Biomedical Engineering, University of California, Irvine, CA 92697-2715, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Department\u00a0of Chemical Engineering and Materials Science, University of California, 916 Engineering Tower, Irvine, CA 92697-2575, USA","institution_ids":["https://openalex.org/I204250578"]},{"raw_affiliation_string":"Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine, CA 92697-1475, USA","institution_ids":["https://openalex.org/I204250578","https://openalex.org/I4210133819"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5083213372"],"corresponding_institution_ids":["https://openalex.org/I204250578","https://openalex.org/I4210133819"],"apc_list":null,"apc_paid":null,"fwci":1.6018,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.82917922,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"9","issue":"71","first_page":"1156","last_page":"1167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10732","display_name":"Laser Material Processing Techniques","score":0.6298999786376953,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10732","display_name":"Laser Material Processing Techniques","score":0.6298999786376953,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.19949999451637268,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.030899999663233757,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/laser-microbeam","display_name":"laser microbeam","score":0.7080000042915344},{"id":"https://openalex.org/keywords/photoresist","display_name":"photoresist","score":0.7979999780654907},{"id":"https://openalex.org/keywords/cell-selection","display_name":"cell selection","score":0.5590000152587891},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.6850000023841858},{"id":"https://openalex.org/keywords/hydrodynamic-shear-stress","display_name":"hydrodynamic shear stress","score":0.9150000214576721},{"id":"https://openalex.org/keywords/laser-pulse-energy","display_name":"laser pulse energy","score":0.7699999809265137},{"id":"https://openalex.org/keywords/necrosis","display_name":"necrosis","score":0.8069999814033508},{"id":"https://openalex.org/keywords/time-resolved-interferometry","display_name":"time-resolved interferometry","score":0.7839999794960022},{"id":"https://openalex.org/keywords/computational-fluid-dynamics","display_name":"computational fluid dynamics","score":0.9900000095367432}],"concepts":[{"id":"https://openalex.org/C2777152588","wikidata":"https://www.wikidata.org/wiki/Q6839237","display_name":"Microbeam","level":2,"score":0.7708615064620972},{"id":"https://openalex.org/C51413319","wikidata":"https://www.wikidata.org/wiki/Q505996","display_name":"Pallet","level":2,"score":0.6608926057815552},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5363273620605469},{"id":"https://openalex.org/C546029482","wikidata":"https://www.wikidata.org/wiki/Q560","display_name":"Helium","level":2,"score":0.42259421944618225},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.3832589089870453},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.3270261585712433},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3034049868583679},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.08869102597236633},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.07544338703155518},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002469","descriptor_name":"Cell Separation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008863","descriptor_name":"Microspheres","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":true},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D061346","descriptor_name":"Laser Capture Microdissection","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1098/rsif.2011.0691","doi":"https://doi.org/10.1098/rsif.2011.0691","is_oa":false,"landing_page_url":"https://doi.org/10.1098/rsif.2011.0691","pdf_url":null,"source":{"id":"https://openalex.org/S129150467","display_name":"Journal of The Royal Society Interface","issn_l":"1742-5662","issn":["1742-5662","1742-5689"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319787","host_organization_name":"Royal Society","host_organization_lineage":["https://openalex.org/P4310319787"],"host_organization_lineage_names":["Royal Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of The Royal Society Interface","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3350736","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3350736","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J R Soc Interface","raw_type":"Text"},{"id":"pmid:22158840","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22158840","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Royal Society, Interface","raw_type":"Journal Article"},{"id":"pmh:cdr.lib.unc.edu:9k41zn233","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.17615/4x4h-ck24","pdf_url":null,"source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of the Royal Society, Interface / The Royal Society, 9(71)","raw_type":"Article"},{"id":"doi:10.17615/4x4h-ck24","doi":"https://doi.org/10.17615/4x4h-ck24","is_oa":true,"landing_page_url":"https://doi.org/10.17615/4x4h-ck24","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3350736","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3350736","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J R Soc Interface","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G284713275","display_name":"Rapid Genetic Engineering of Stem Cells","funder_award_id":"R01HG004843","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G4607486877","display_name":"A Laser Microbeam Biotechnology Resource","funder_award_id":"P41RR001192","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G9000199918","display_name":null,"funder_award_id":"RR-01192)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G906218860","display_name":"Versatile system to select and expand individual or multiple adherent-type cells","funder_award_id":"R43RR025980","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332688","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W623404449","https://openalex.org/W1580322100","https://openalex.org/W1607071030","https://openalex.org/W1971018355","https://openalex.org/W1972223695","https://openalex.org/W1977207955","https://openalex.org/W1984805673","https://openalex.org/W1985848423","https://openalex.org/W1995873025","https://openalex.org/W1997636911","https://openalex.org/W2008597357","https://openalex.org/W2009624211","https://openalex.org/W2016032119","https://openalex.org/W2029549744","https://openalex.org/W2030687926","https://openalex.org/W2039634179","https://openalex.org/W2041090878","https://openalex.org/W2041674158","https://openalex.org/W2043094315","https://openalex.org/W2050712921","https://openalex.org/W2054157952","https://openalex.org/W2055884199","https://openalex.org/W2066791160","https://openalex.org/W2086009140","https://openalex.org/W2093783043","https://openalex.org/W2114991539","https://openalex.org/W2118590121","https://openalex.org/W2124059811","https://openalex.org/W2126733082","https://openalex.org/W2134850866","https://openalex.org/W2156771492","https://openalex.org/W2159174770","https://openalex.org/W2224532265","https://openalex.org/W2417802793"],"related_works":["https://openalex.org/W2156771492","https://openalex.org/W7030253971","https://openalex.org/W2016032119","https://openalex.org/W2126733082","https://openalex.org/W2012110242","https://openalex.org/W2118590121","https://openalex.org/W73730130","https://openalex.org/W1985848423","https://openalex.org/W2043416849","https://openalex.org/W2092046732"],"abstract_inverted_index":{"We":[0,31],"use":[1,160],"time-resolved":[2,66],"interferometry,":[3],"fluorescence":[4],"assays":[5],"and":[6,40,115,211,243,266,295],"computational":[7],"fluid":[8],"dynamics":[9,265],"(CFD)":[10],"simulations":[11,91],"to":[12,21,45,101,216],"examine":[13,192],"the":[14,33,46,51,60,94,127,132,138,144,154,159,177,184,193,217,293],"viability":[15,148,194,222],"of":[16,27,35,149,161,169,195,220,225,246,297],"confluent":[17,150],"adherent":[18,298],"cell":[19,119,151,197,221],"monolayers":[20,152,198],"selection":[22,296],"via":[23],"laser":[24,36,72,207,230,287],"microbeam":[25,37,208,231],"release":[26,56,62,79,201,237,264,290],"photoresist":[28],"polymer":[29],"micropallets.":[30],"demonstrate":[32],"importance":[34],"pulse":[38,73,163,209],"energy":[39,74,210],"focal":[41,212],"volume":[42,213],"position":[43,214],"relative":[44],"glass-pallet":[47],"interface":[48],"in":[49,71,76,98,166,223,234],"governing":[50],"threshold":[52],"energies":[53,164],"for":[54,171,206,281,286,292],"pallet":[55,61,78,95,133,145,155,178,185,200,236,263,289],"as":[57,59],"well":[58],"dynamics.":[63],"Measurements":[64],"using":[65],"interferometry":[67],"show":[68,125,202],"that":[69,81,93,107,126,158,191,203,261],"increases":[70],"result":[75,233],"increasing":[77],"velocities":[80,238],"can":[82,108],"approach":[83],"10":[84],"m":[85,241],"s(-1)":[86,242],"through":[87],"aqueous":[88],"media.":[89],"CFD":[90,122],"reveal":[92],"motion":[96],"results":[97,124,165,256],"cellular":[99,244,273],"exposure":[100,245],"transient":[102,247,268],"hydrodynamic":[103,248],"shear":[104,129,140,249,269],"stress":[105,130],"amplitudes":[106],"exceed":[109],"100":[110],"kPa":[111],"on":[112,131,143,153],"microsecond":[113],"timescales,":[114],"which":[116],"produces":[117],"reduced":[118],"viability.":[120,274],"Moreover,":[121],"simulation":[123],"maximum":[128,235],"surface":[134,156],"varies":[135],"spatially,":[136],"with":[137,271],"largest":[139],"stresses":[141,250,270],"occurring":[142],"periphery.":[146],"Cell":[147],"confirms":[157],"larger":[162],"increased":[167],"rates":[168],"necrosis":[170],"those":[172],"cells":[173,181],"situated":[174,182],"away":[175],"from":[176],"centre,":[179],"while":[180],"at":[183],"centre":[186],"remain":[187],"viable.":[188],"Nevertheless,":[189],"experiments":[190],"these":[196,255],"following":[199],"proper":[204],"choices":[205],"lead":[215],"routine":[218],"achievement":[219],"excess":[224],"90":[226],"per":[227],"cent.":[228],"These":[229],"parameters":[232],"below":[239,251],"6":[240],"20":[252],"kPa.":[253],"Collectively,":[254],"provide":[257],"a":[258,277],"mechanistic":[259,279],"understanding":[260],"relates":[262],"associated":[267],"subsequent":[272],"This":[275],"provides":[276],"quantitative,":[278],"basis":[280],"determining":[282],"optimal":[283],"operating":[284],"conditions":[285],"microbeam-based":[288],"systems":[291],"isolation":[294],"cells.":[299]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}