{"id":"https://openalex.org/W2147366336","doi":"https://doi.org/10.1200/jco.2005.02.7227","title":"Multipopulation Analysis of Polymorphisms in Five Mononucleotide Repeats Used to Determine the Microsatellite Instability Status of Human Tumors","display_name":"Multipopulation Analysis of Polymorphisms in Five Mononucleotide Repeats Used to Determine the Microsatellite Instability Status of Human Tumors","publication_year":2005,"publication_date":"2005-12-06","ids":{"openalex":"https://openalex.org/W2147366336","doi":"https://doi.org/10.1200/jco.2005.02.7227","mag":"2147366336","pmid":"https://pubmed.ncbi.nlm.nih.gov/16330668"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2005.02.7227","doi":"https://doi.org/10.1200/jco.2005.02.7227","is_oa":true,"landing_page_url":"https://doi.org/10.1200/jco.2005.02.7227","pdf_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2005.02.7227?role=tab","source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2005.02.7227?role=tab","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035282335","display_name":"Olivier Buhard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":false,"raw_author_name":"Olivier Buhard","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014660258","display_name":"Francesca Cattaneo","orcid":"https://orcid.org/0000-0003-3089-7077","observed_orcids":["https://orcid.org/0000-0003-3089-7077"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":false,"raw_author_name":"Francesca Cattaneo","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109236200","display_name":"Yick Fu Wong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":false,"raw_author_name":"Yick Fu Wong","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113543533","display_name":"So Fan Yim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":false,"raw_author_name":"So Fan Yim","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031247002","display_name":"Eitan Friedman","orcid":"https://orcid.org/0000-0002-6745-1733","observed_orcids":["https://orcid.org/0000-0002-6745-1733"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":false,"raw_author_name":"Eitan Friedman","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084448152","display_name":"Jean\u2013Fran\u00e7ois Fl\u00e9jou","orcid":"https://orcid.org/0000-0002-4971-2434","observed_orcids":["https://orcid.org/0000-0002-4971-2434"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":false,"raw_author_name":"Jean-Fran\u00e7ois Flejou","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038592146","display_name":"Alex Duval","orcid":"https://orcid.org/0000-0003-1534-1724","observed_orcids":["https://orcid.org/0000-0003-1534-1724"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":false,"raw_author_name":"Alex Duval","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,","institution_ids":["https://openalex.org/I25217355"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5106486028","display_name":"Richard Hamelin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"HK","type":"education","lineage":["https://openalex.org/I177725633"]},{"id":"https://openalex.org/I25217355","display_name":"University of Pavia","ror":"https://ror.org/00s6t1f81","country_code":"IT","type":"education","lineage":["https://openalex.org/I25217355"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]},{"id":"https://openalex.org/I2802309713","display_name":"Fondation Jean Dausset-CEPH","ror":"https://ror.org/01rje3r53","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I2802309713"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4210114914","display_name":"Prince of Wales Hospital","ror":"https://ror.org/02827ca86","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I1294586568","https://openalex.org/I4210114914"]}],"countries":["CN","FR","HK","IL","IT"],"is_corresponding":true,"raw_author_name":"Richard Hamelin","raw_affiliation_strings":["From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) U434, Centre d'Etude du Polymorphisme Humain (CEPH); Service d'Anatomo-Pathologie, H\u00f4pital Saint-Antoine, Paris, France; Dipartimento di Genetica e Microbiologica, University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong; and the Institute of Genetics, Chaim Sheba Medical Center, Tel-Hashomer, Israel","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong;","institution_ids":["https://openalex.org/I177725633","https://openalex.org/I4210114914"]},{"raw_affiliation_string":"INSERM U434-CEPH, 27 rue Juliette Dodu, 75010 Paris, France;","institution_ids":["https://openalex.org/I154526488"]},{"raw_affiliation_string":"University of Pavia, Pavia, Italy; Department of Obstetrics & Gynaecology,","institution_ids":["https://openalex.org/I25217355"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5106486028"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177725633","https://openalex.org/I25217355","https://openalex.org/I2799810450","https://openalex.org/I2802309713","https://openalex.org/I4210102928","https://openalex.org/I4210114914"],"apc_list":null,"apc_paid":null,"fwci":4.2403,"has_fulltext":true,"cited_by_count":246,"citation_normalized_percentile":{"value":0.94010572,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"24","issue":"2","first_page":"241","last_page":"251"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microsatellite-instability","display_name":"microsatellite instability","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mononucleotide-repeats","display_name":"mononucleotide repeats","score":0.9309999942779541},{"id":"https://openalex.org/keywords/dna-mismatch-repair","display_name":"DNA mismatch repair","score":0.7699999809265137},{"id":"https://openalex.org/keywords/variant-alleles","display_name":"variant alleles","score":0.5910000205039978},{"id":"https://openalex.org/keywords/germline-polymorphisms","display_name":"germline polymorphisms","score":0.753000020980835},{"id":"https://openalex.org/keywords/population-genetic-diversity","display_name":"population genetic variation","score":0.5440000295639038},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.628000020980835},{"id":"https://openalex.org/keywords/gastrointestinal-cancer","display_name":"gastrointestinal cancer","score":0.6970000267028809},{"id":"https://openalex.org/keywords/adjuvant-chemotherapy-response","display_name":"adjuvant chemotherapy response","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C2779767149","wikidata":"https://www.wikidata.org/wiki/Q488212","display_name":"Microsatellite instability","level":5,"score":0.8914827704429626},{"id":"https://openalex.org/C61320498","wikidata":"https://www.wikidata.org/wiki/Q265193","display_name":"Microsatellite","level":4,"score":0.7126250863075256},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5632442235946655},{"id":"https://openalex.org/C109825262","wikidata":"https://www.wikidata.org/wiki/Q1139164","display_name":"Germline","level":3,"score":0.5183109045028687},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.5097703337669373},{"id":"https://openalex.org/C60748783","wikidata":"https://www.wikidata.org/wiki/Q2984243","display_name":"DNA mismatch repair","level":4,"score":0.47424808144569397},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.47296756505966187},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4528941512107849},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.45269495248794556},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4439045786857605},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.438017874956131},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42480623722076416},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3604525625705719},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15482157468795776},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005828","descriptor_name":"Genetics, Population","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011110","descriptor_name":"Polymorphism, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012091","descriptor_name":"Repetitive Sequences, Nucleic Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018895","descriptor_name":"Microsatellite Repeats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1200/jco.2005.02.7227","doi":"https://doi.org/10.1200/jco.2005.02.7227","is_oa":true,"landing_page_url":"https://doi.org/10.1200/jco.2005.02.7227","pdf_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2005.02.7227?role=tab","source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},{"id":"pmid:16330668","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16330668","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical oncology : official journal of the American Society of Clinical Oncology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1200/jco.2005.02.7227","doi":"https://doi.org/10.1200/jco.2005.02.7227","is_oa":true,"landing_page_url":"https://doi.org/10.1200/jco.2005.02.7227","pdf_url":"https://ascopubs.org/doi/pdfdirect/10.1200/JCO.2005.02.7227?role=tab","source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7799999713897705}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"},{"id":"https://openalex.org/F4320322651","display_name":"Consiglio Nazionale delle Ricerche","ror":"https://ror.org/04zaypm56"},{"id":"https://openalex.org/F4320326049","display_name":"Assistance publique-H\u00f4pitaux de Paris","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2147366336.pdf","grobid_xml":"https://content.openalex.org/works/W2147366336.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W16278512","https://openalex.org/W1499941079","https://openalex.org/W1506004759","https://openalex.org/W1520825092","https://openalex.org/W1669049638","https://openalex.org/W1903698419","https://openalex.org/W1977284533","https://openalex.org/W1981112371","https://openalex.org/W1984439054","https://openalex.org/W1984547934","https://openalex.org/W1986937402","https://openalex.org/W1995819860","https://openalex.org/W2010053675","https://openalex.org/W2011442347","https://openalex.org/W2017928414","https://openalex.org/W2044643325","https://openalex.org/W2053827853","https://openalex.org/W2097576041","https://openalex.org/W2098476483","https://openalex.org/W2103645868","https://openalex.org/W2127951115","https://openalex.org/W2128793721","https://openalex.org/W2139964075","https://openalex.org/W2141042406","https://openalex.org/W2141366450","https://openalex.org/W2143895061","https://openalex.org/W2154546296","https://openalex.org/W2165308016"],"related_works":["https://openalex.org/W2143895061","https://openalex.org/W2104818405","https://openalex.org/W1998655295","https://openalex.org/W7100722189","https://openalex.org/W1982129441","https://openalex.org/W2782769831","https://openalex.org/W2317839121","https://openalex.org/W2011442347","https://openalex.org/W7100434355","https://openalex.org/W2138709172"],"abstract_inverted_index":{"PURPOSE:":[0],"Human":[1],"gastrointestinal":[2],"tumors":[3,36,233],"with":[4,23,34,44,46,227],"inactivated":[5],"DNA":[6,126,150,171],"mismatch":[7],"repair":[8],"system":[9],"(microsatellite":[10],"instability":[11,236],"[MSI]":[12],"tumors)":[13],"have":[14],"distinct":[15],"molecular":[16],"and":[17,20,109,117,136,188],"clinicopathologic":[18],"profiles,":[19],"are":[21,122],"associated":[22],"favorable":[24],"prognosis.":[25],"There":[26],"is":[27,68],"evidence":[28],"suggesting":[29],"that":[30,73,111,248],"colorectal":[31],"cancer":[32],"patients":[33,45],"MSI":[35,53,76,104,142,232,250],"respond":[37],"differently":[38],"to":[39,101],"adjuvant":[40],"chemotherapy":[41],"as":[42],"compared":[43],"non-MSI":[47],"tumors.":[48],"Finally,":[49],"determination":[50,143],"of":[51,63,86,97,106,127,133,165,184,209,241],"the":[52,61,103,128,145,182,202,242,256,264],"status":[54,105,251],"has":[55],"clinical":[56],"application":[57],"for":[58,75,140,147,192,259,266],"assisting":[59],"in":[60,81,124,151,169,237],"diagnosis":[62],"suspected":[64],"hereditary":[65],"cases.":[66],"It":[67],"thus":[69],"becoming":[70],"increasingly":[71],"recognized":[72],"testing":[74],"should":[77],"be":[78,138,253],"conducted":[79],"systematically":[80],"all":[82,260],"human":[83,107,261],"cancers":[84],"potentially":[85],"this":[87,112,152,158],"type.":[88],"We":[89,246],"recently":[90],"described":[91],"a":[92,162],"pentaplex":[93,257],"polymerase":[94],"chain":[95],"reaction":[96,258],"five":[98,166,243],"mononucleotide":[99,167],"repeats":[100],"establish":[102],"tumors,":[108],"showed":[110,196,206],"assay":[113],"was":[114],"100%":[115],"sensitive":[116],"specific.":[118],"Moreover,":[119],"these":[120],"markers":[121,168,195,226],"quasimonomorphic":[123],"germline":[125,170],"white":[129],"population":[130],"(ie,":[131],"individuals":[132,174,205],"Eurasian":[134],"origin),":[135],"could":[137],"used":[139],"tumor":[141,249],"without":[144,263],"requirement":[146],"matching":[148,267],"normal":[149,268],"group.":[153],"PATIENTS":[154],"AND":[155],"METHODS:":[156],"In":[157],"study,":[159],"we":[160],"analyzed":[161],"comparable":[163],"panel":[164],"from":[172],"1,206":[173],"encompassing":[175],"55":[176],"different":[177],"populations":[178,262],"worldwide.":[179],"Results":[180],"With":[181],"exception":[183],"two":[185,222],"Biaka":[186],"Pygmies":[187],"one":[189,217],"San":[190],"individual":[191],"whom":[193],"three":[194],"variant":[197,210,228],"alleles":[198,208],"(three":[199],"cases":[200,213,219,224],"[0.2%]),":[201],"remaining":[203],"1,203":[204],"no":[207],"size":[211],"(1,055":[212],"[87.5%]),":[214],"or":[215,221],"only":[216],"(122":[218],"[10.1%])":[220],"(26":[223],"[2.2%])":[225],"alleles.":[229],"All":[230],"60":[231],"investigated":[234],"display":[235],"at":[238],"least":[239],"four":[240],"markers.":[244],"CONCLUSION:":[245],"demonstrated":[247],"can":[252],"determined":[254],"using":[255],"need":[265],"DNA.":[269]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":17},{"year":2021,"cited_by_count":22},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":15},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":12},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":15},{"year":2013,"cited_by_count":13},{"year":2012,"cited_by_count":8}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
