{"id":"https://openalex.org/W2147356744","doi":"https://doi.org/10.1016/j.carbon.2005.08.006","title":"Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice","display_name":"Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice","publication_year":2005,"publication_date":"2005-09-29","ids":{"openalex":"https://openalex.org/W2147356744","doi":"https://doi.org/10.1016/j.carbon.2005.08.006","mag":"2147356744"},"language":"en","primary_location":{"id":"doi:10.1016/j.carbon.2005.08.006","doi":"https://doi.org/10.1016/j.carbon.2005.08.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carbon.2005.08.006","pdf_url":null,"source":{"id":"https://openalex.org/S188605413","display_name":"Carbon","issn_l":"0008-6223","issn":["0008-6223","1873-3891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbon","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://soar-ir.repo.nii.ac.jp/records/12736","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111976049","display_name":"Shozo Koyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shozo Koyama","raw_affiliation_strings":["Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002777558","display_name":"Morinobu Endo","orcid":"https://orcid.org/0000-0002-7034-3143","observed_orcids":["https://orcid.org/0000-0002-7034-3143"]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Morinobu Endo","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005760245","display_name":"Yoong Ahm Kim","orcid":"https://orcid.org/0000-0003-4074-7515","observed_orcids":["https://orcid.org/0000-0003-4074-7515"]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoong-Ahm Kim","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101169121","display_name":"Takuya Hayashi","orcid":"https://orcid.org/0000-0002-3779-281X","observed_orcids":["https://orcid.org/0000-0002-3779-281X","https://orcid.org/0000-0002-4065-1807"]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takuya Hayashi","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022136795","display_name":"Takashi Yanagisawa","orcid":"https://orcid.org/0000-0001-5376-1055","observed_orcids":["https://orcid.org/0000-0001-5376-1055"]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takashi Yanagisawa","raw_affiliation_strings":["Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Electronic Engineering, Faculty of Engineering, Shinshu University, Nagano 380-8553, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065301540","display_name":"Kazumasa Osaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazumasa Osaka","raw_affiliation_strings":["Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082012831","display_name":"Haruhide Koyama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Haruhide Koyama","raw_affiliation_strings":["Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051655941","display_name":"Hisao Haniu","orcid":"https://orcid.org/0000-0001-5195-9711","observed_orcids":["https://orcid.org/0000-0001-5195-9711"]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisao Haniu","raw_affiliation_strings":["Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan","institution_ids":["https://openalex.org/I137975476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035469007","display_name":"Naomi Kuroiwa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I137975476","display_name":"Shinshu University","ror":"https://ror.org/0244rem06","country_code":"JP","type":"education","lineage":["https://openalex.org/I137975476"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Naomi Kuroiwa","raw_affiliation_strings":["Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Integrative Physiology and Bio-System Control, School of Medicine, Shinshu University, Matsumoto 390-8621, Japan","institution_ids":["https://openalex.org/I137975476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5002777558"],"corresponding_institution_ids":["https://openalex.org/I137975476"],"apc_list":{"value":4830,"currency":"USD","value_usd":4830},"apc_paid":null,"fwci":4.1935,"has_fulltext":true,"cited_by_count":81,"citation_normalized_percentile":{"value":0.93693587,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"44","issue":"6","first_page":"1079","last_page":"1092"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12627","display_name":"Graphene and Nanomaterials Applications","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12627","display_name":"Graphene and Nanomaterials Applications","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.06960000097751617,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10079","display_name":"Nanoparticles: synthesis and applications","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbon-nanotubes","display_name":"carbon nanotubes","score":0.9980000257492065},{"id":"https://openalex.org/keywords/single-walled-carbon-nanotubes","display_name":"single-walled carbon nanotubes","score":0.8989999890327454},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.9039999842643738},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":1.0},{"id":"https://openalex.org/keywords/mhc-class-i","display_name":"MHC class I","score":0.7689999938011169},{"id":"https://openalex.org/keywords/mhc-class-ii","display_name":"MHC class II","score":0.9980000257492065},{"id":"https://openalex.org/keywords/immune-response","display_name":"immune response","score":0.42500001192092896},{"id":"https://openalex.org/keywords/subcutaneous-implantation","display_name":"subcutaneous implantation","score":0.9240000247955322},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":0.878000020980835},{"id":"https://openalex.org/keywords/nanoparticle-toxicity","display_name":"nanoparticle toxicity","score":0.6819999814033508},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.4230000078678131}],"concepts":[{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.7716753482818604},{"id":"https://openalex.org/C513720949","wikidata":"https://www.wikidata.org/wiki/Q1778729","display_name":"Carbon nanotube","level":2,"score":0.6941706538200378},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.6081316471099854},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.4148097038269043},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.39982104301452637},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3757091760635376},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36997729539871216},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3299415707588196},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.27369874715805054},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27194690704345703},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20873600244522095}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.carbon.2005.08.006","doi":"https://doi.org/10.1016/j.carbon.2005.08.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.carbon.2005.08.006","pdf_url":null,"source":{"id":"https://openalex.org/S188605413","display_name":"Carbon","issn_l":"0008-6223","issn":["0008-6223","1873-3891"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-2","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carbon","raw_type":"journal-article"},{"id":"pmh:oai:irdb.nii.ac.jp:00990:0001376133","doi":null,"is_oa":true,"landing_page_url":"https://soar-ir.repo.nii.ac.jp/records/12736","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Carbon","raw_type":"journal article"},{"id":"pmh:oai:soar-ir.repo.nii.ac.jp:00012736","doi":null,"is_oa":true,"landing_page_url":"https://soar-ir.repo.nii.ac.jp/record/12736/files/No_8_Carbon_2006.pdf","pdf_url":"https://soar-ir.repo.nii.ac.jp/record/12736/files/No_8_Carbon_2006.pdf","source":{"id":"https://openalex.org/S4306402150","display_name":"SOAR (Shinshu University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I137975476","host_organization_name":"Shinshu University","host_organization_lineage":["https://openalex.org/I137975476"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:00990:0001376133","doi":null,"is_oa":true,"landing_page_url":"https://soar-ir.repo.nii.ac.jp/records/12736","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Carbon","raw_type":"journal article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3839639422","display_name":null,"funder_award_id":"16201024","funder_id":"https://openalex.org/F4320320912","funder_display_name":"Ministry of Education, Culture, Sports, Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2147356744.pdf","grobid_xml":"https://content.openalex.org/works/W2147356744.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W91773989","https://openalex.org/W609684103","https://openalex.org/W1973164347","https://openalex.org/W1979839814","https://openalex.org/W1986097431","https://openalex.org/W1994869187","https://openalex.org/W2007920851","https://openalex.org/W2011934320","https://openalex.org/W2012018505","https://openalex.org/W2017712799","https://openalex.org/W2030391080","https://openalex.org/W2037831947","https://openalex.org/W2052971899","https://openalex.org/W2053038617","https://openalex.org/W2056955697","https://openalex.org/W2057891380","https://openalex.org/W2076184158","https://openalex.org/W2077706151","https://openalex.org/W2083079495","https://openalex.org/W2111163976","https://openalex.org/W2151609134","https://openalex.org/W2168893672","https://openalex.org/W2313466778","https://openalex.org/W4246958924","https://openalex.org/W4250113749","https://openalex.org/W4300175912"],"related_works":["https://openalex.org/W2078748575","https://openalex.org/W2053464834","https://openalex.org/W2087743834","https://openalex.org/W2107604441","https://openalex.org/W2025403161","https://openalex.org/W2514718028","https://openalex.org/W2053634295","https://openalex.org/W2059165000","https://openalex.org/W2118008112","https://openalex.org/W1996168808"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2016-06-24T00:00:00"}