{"id":"https://openalex.org/W2147087645","doi":"https://doi.org/10.1007/s11010-008-9744-2","title":"Nutrigenomic basis of beneficial effects of chromium(III) on obesity and diabetes","display_name":"Nutrigenomic basis of beneficial effects of chromium(III) on obesity and diabetes","publication_year":2008,"publication_date":"2008-07-17","ids":{"openalex":"https://openalex.org/W2147087645","doi":"https://doi.org/10.1007/s11010-008-9744-2","mag":"2147087645","pmid":"https://pubmed.ncbi.nlm.nih.gov/18636317"},"language":"en","primary_location":{"id":"doi:10.1007/s11010-008-9744-2","doi":"https://doi.org/10.1007/s11010-008-9744-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11010-008-9744-2","pdf_url":null,"source":{"id":"https://openalex.org/S11742566","display_name":"Molecular and Cellular Biochemistry","issn_l":"0300-8177","issn":["0300-8177","1573-4919"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biochemistry","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074434612","display_name":"Francis C. Lau","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francis C. Lau","raw_affiliation_strings":["InterHealth Research Center, Benicia, CA, 94590, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"InterHealth Research Center, Benicia, CA, 94590, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025047849","display_name":"Manashi Bagchi","orcid":"https://orcid.org/0000-0002-1527-6419","observed_orcids":["https://orcid.org/0000-0002-1527-6419"]},"institutions":[{"id":"https://openalex.org/I1283951974","display_name":"IntraHealth International","ror":"https://ror.org/032y7r881","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1283951974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manashi Bagchi","raw_affiliation_strings":["InterHealth Research Center, Benicia, USA","InterHealth Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"InterHealth Research Center, Benicia, USA","institution_ids":[]},{"raw_affiliation_string":"InterHealth Research Center","institution_ids":["https://openalex.org/I1283951974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056267400","display_name":"Chandan K. Sen","orcid":"https://orcid.org/0000-0003-3151-5202","observed_orcids":["https://orcid.org/0000-0003-3151-5202","https://orcid.org/0000-0002-2936-417X"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chandan K. Sen","raw_affiliation_strings":["Laboratory of Molecular Medicine, Department of Surgery, Ohio State University, Columbus, USA","Ohio State University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Medicine, Department of Surgery, Ohio State University, Columbus, USA","institution_ids":["https://openalex.org/I52357470"]},{"raw_affiliation_string":"Ohio State University","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019498762","display_name":"Debasis Bagchi","orcid":"https://orcid.org/0000-0001-9478-6427","observed_orcids":["https://orcid.org/0000-0001-9478-6427"]},"institutions":[{"id":"https://openalex.org/I2800482329","display_name":"CHI Health Creighton University Medical Center - Bergan Mercy","ror":"https://ror.org/03z1w3b90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800482329","https://openalex.org/I2802665030","https://openalex.org/I2802797007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Debasis Bagchi","raw_affiliation_strings":["Department of Pharmacy Sciences, Creighton University Medical Center, Omaha, USA","InterHealth Research Center, Benicia, USA","Creighton University Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Sciences, Creighton University Medical Center, Omaha, USA","institution_ids":["https://openalex.org/I2800482329"]},{"raw_affiliation_string":"InterHealth Research Center, Benicia, USA","institution_ids":[]},{"raw_affiliation_string":"Creighton University Medical Center","institution_ids":["https://openalex.org/I2800482329"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5019498762"],"corresponding_institution_ids":["https://openalex.org/I2800482329"],"apc_list":{"value":4190,"currency":"USD","value_usd":4190},"apc_paid":null,"fwci":0.6787,"has_fulltext":false,"cited_by_count":86,"citation_normalized_percentile":{"value":0.54919908,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"317","issue":"1-2","first_page":"1","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.454800009727478,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.454800009727478,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.3212999999523163,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11972","display_name":"Chromium effects and bioremediation","score":0.18330000340938568,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cr-iii","display_name":"trivalent chromium","score":0.7609999775886536},{"id":"https://openalex.org/keywords/nutrigenomics","display_name":"nutrigenomics","score":0.902999997138977},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8629999756813049},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9079999923706055},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":1.0},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8629999756813049},{"id":"https://openalex.org/keywords/chromium-nicotinate","display_name":"chromium nicotinate","score":0.9670000076293945},{"id":"https://openalex.org/keywords/dietary-supplements","display_name":"dietary supplements","score":0.7009999752044678},{"id":"https://openalex.org/keywords/insulin-sensitizers","display_name":"insulin sensitizers","score":0.9229999780654907},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5690000057220459},{"id":"https://openalex.org/keywords/serum-cholesterol","display_name":"serum cholesterol","score":0.7390000224113464},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.8768013715744019},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.6948584318161011},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.6241646409034729},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.6226842999458313},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.6192835569381714},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5634649991989136},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5366133451461792},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5314594507217407},{"id":"https://openalex.org/C97633540","wikidata":"https://www.wikidata.org/wiki/Q4328195","display_name":"Nutrigenomics","level":3,"score":0.5080976486206055},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5017879009246826},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4525127708911896},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3490968346595764},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3117024302482605},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08105847239494324},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.05512732267379761}],"mesh":[{"descriptor_ui":"D001682","descriptor_name":"Biological Availability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002857","descriptor_name":"Chromium","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D002857","descriptor_name":"Chromium","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D002857","descriptor_name":"Chromium","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019587","descriptor_name":"Dietary Supplements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054647","descriptor_name":"Nutrigenomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11010-008-9744-2","doi":"https://doi.org/10.1007/s11010-008-9744-2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11010-008-9744-2","pdf_url":null,"source":{"id":"https://openalex.org/S11742566","display_name":"Molecular and Cellular Biochemistry","issn_l":"0300-8177","issn":["0300-8177","1573-4919"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Biochemistry","raw_type":"journal-article"},{"id":"pmid:18636317","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18636317","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":117,"referenced_works":["https://openalex.org/W43236269","https://openalex.org/W110092479","https://openalex.org/W189077365","https://openalex.org/W207395144","https://openalex.org/W338199551","https://openalex.org/W587764945","https://openalex.org/W608772252","https://openalex.org/W1569214109","https://openalex.org/W1591439304","https://openalex.org/W1653594454","https://openalex.org/W1901823973","https://openalex.org/W1948540585","https://openalex.org/W1965199608","https://openalex.org/W1970605811","https://openalex.org/W1971256871","https://openalex.org/W1971939048","https://openalex.org/W1972656394","https://openalex.org/W1972811868","https://openalex.org/W1984255682","https://openalex.org/W1984380914","https://openalex.org/W1985115509","https://openalex.org/W1985882893","https://openalex.org/W1991708719","https://openalex.org/W1999022873","https://openalex.org/W2001657480","https://openalex.org/W2004934188","https://openalex.org/W2006500793","https://openalex.org/W2007469138","https://openalex.org/W2007691338","https://openalex.org/W2007708099","https://openalex.org/W2008266059","https://openalex.org/W2010937069","https://openalex.org/W2011543288","https://openalex.org/W2012314200","https://openalex.org/W2012976406","https://openalex.org/W2013195172","https://openalex.org/W2018251513","https://openalex.org/W2018739369","https://openalex.org/W2024681988","https://openalex.org/W2029710018","https://openalex.org/W2032110401","https://openalex.org/W2034102313","https://openalex.org/W2036233460","https://openalex.org/W2037561129","https://openalex.org/W2042107619","https://openalex.org/W2043336846","https://openalex.org/W2044170398","https://openalex.org/W2044487287","https://openalex.org/W2049819363","https://openalex.org/W2050710651","https://openalex.org/W2052449006","https://openalex.org/W2053430176","https://openalex.org/W2057831265","https://openalex.org/W2060781005","https://openalex.org/W2063372431","https://openalex.org/W2067498398","https://openalex.org/W2067730295","https://openalex.org/W2067997277","https://openalex.org/W2068213628","https://openalex.org/W2073828305","https://openalex.org/W2075661480","https://openalex.org/W2080575714","https://openalex.org/W2081745487","https://openalex.org/W2082383524","https://openalex.org/W2088994625","https://openalex.org/W2089508497","https://openalex.org/W2089640158","https://openalex.org/W2092208645","https://openalex.org/W2094107803","https://openalex.org/W2096070544","https://openalex.org/W2097766603","https://openalex.org/W2097977544","https://openalex.org/W2099678981","https://openalex.org/W2103380947","https://openalex.org/W2104261909","https://openalex.org/W2107955212","https://openalex.org/W2108983113","https://openalex.org/W2109473323","https://openalex.org/W2111008516","https://openalex.org/W2111432346","https://openalex.org/W2111648233","https://openalex.org/W2111671928","https://openalex.org/W2120308420","https://openalex.org/W2130546974","https://openalex.org/W2132125652","https://openalex.org/W2132223223","https://openalex.org/W2132399049","https://openalex.org/W2133601241","https://openalex.org/W2134141508","https://openalex.org/W2135628848","https://openalex.org/W2135647402","https://openalex.org/W2137129438","https://openalex.org/W2137721401","https://openalex.org/W2139727647","https://openalex.org/W2142209532","https://openalex.org/W2142490292","https://openalex.org/W2144327256","https://openalex.org/W2145090528","https://openalex.org/W2145688382","https://openalex.org/W2147098206","https://openalex.org/W2151727390","https://openalex.org/W2154382681","https://openalex.org/W2158829081","https://openalex.org/W2160439881","https://openalex.org/W2162878256","https://openalex.org/W2165811484","https://openalex.org/W2168858291","https://openalex.org/W2189175952","https://openalex.org/W2261834796","https://openalex.org/W2321092733","https://openalex.org/W2332019780","https://openalex.org/W2341790447","https://openalex.org/W2409236211","https://openalex.org/W2482650030","https://openalex.org/W2490586415","https://openalex.org/W2551221020","https://openalex.org/W4241624607"],"related_works":["https://openalex.org/W2010205820","https://openalex.org/W2912664692","https://openalex.org/W7099818703","https://openalex.org/W2612815033","https://openalex.org/W2083017610","https://openalex.org/W2030224213","https://openalex.org/W7161661495","https://openalex.org/W2583548688","https://openalex.org/W151966373","https://openalex.org/W7120869835"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}