{"id":"https://openalex.org/W2146648170","doi":"https://doi.org/10.1093/nar/gks296","title":"Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs","display_name":"Emerging functional and mechanistic paradigms of mammalian long non-coding RNAs","publication_year":2012,"publication_date":"2012-04-05","ids":{"openalex":"https://openalex.org/W2146648170","doi":"https://doi.org/10.1093/nar/gks296","mag":"2146648170","pmid":"https://pubmed.ncbi.nlm.nih.gov/22492512","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3413108"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gks296","doi":"https://doi.org/10.1093/nar/gks296","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gks296","pdf_url":"https://academic.oup.com/nar/article-pdf/40/14/6391/7209776/gks296.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/40/14/6391/7209776/gks296.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058414658","display_name":"Victoria A. Moran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V. A. Moran","raw_affiliation_strings":["Center for RNA Molecular Biology, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for RNA Molecular Biology, Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060115650","display_name":"Ranjan Joseph Perera","orcid":"https://orcid.org/0000-0002-5926-3687","observed_orcids":["https://orcid.org/0000-0002-5926-3687"]},"institutions":[{"id":"https://openalex.org/I4390039247","display_name":"Case Comprehensive Cancer Center","ror":"https://ror.org/00fpjq451","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039247","https://openalex.org/I58956616"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. J. Perera","raw_affiliation_strings":["Center for RNA Molecular Biology, 2 Department of Genetics and Genome Sciences, 3 Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 4 Sanford-Burnham Medical Research Institute, Orlando, FL and 5 Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","Case Western Reserve University, Cleveland, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for RNA Molecular Biology, 2 Department of Genetics and Genome Sciences, 3 Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 4 Sanford-Burnham Medical Research Institute, Orlando, FL and 5 Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4390039247","https://openalex.org/I58956616"]},{"raw_affiliation_string":"Case Western Reserve University, Cleveland, United States","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039458149","display_name":"Ahmad Mohammad Khalil","orcid":"https://orcid.org/0000-0002-1081-7300","observed_orcids":["https://orcid.org/0000-0002-1081-7300"]},"institutions":[{"id":"https://openalex.org/I4390039247","display_name":"Case Comprehensive Cancer Center","ror":"https://ror.org/00fpjq451","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039247","https://openalex.org/I58956616"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"A. M. Khalil","raw_affiliation_strings":["Center for RNA Molecular Biology, 2 Department of Genetics and Genome Sciences, 3 Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 4 Sanford-Burnham Medical Research Institute, Orlando, FL and 5 Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","Case Western Reserve University, Cleveland, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for RNA Molecular Biology, 2 Department of Genetics and Genome Sciences, 3 Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH, 4 Sanford-Burnham Medical Research Institute, Orlando, FL and 5 Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA","institution_ids":["https://openalex.org/I4390039247","https://openalex.org/I58956616"]},{"raw_affiliation_string":"Case Western Reserve University, Cleveland, United States","institution_ids":["https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039458149"],"corresponding_institution_ids":["https://openalex.org/I4390039247","https://openalex.org/I58956616"],"apc_list":{"value":3992,"currency":"USD","value_usd":3992},"apc_paid":{"value":3992,"currency":"USD","value_usd":3992},"fwci":4.4852,"has_fulltext":true,"cited_by_count":642,"citation_normalized_percentile":{"value":0.9672524,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"40","issue":"14","first_page":"6391","last_page":"6400"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.996999979019165},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.8930000066757202},{"id":"https://openalex.org/keywords/mammalian-genomes","display_name":"mammalian genomes","score":0.5830000042915344},{"id":"https://openalex.org/keywords/lncrna-dysregulation","display_name":"lncRNA dysregulation","score":0.6380000114440918}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8667969703674316},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6559532880783081},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4872130751609802},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.42331230640411377},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3400007486343384},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2681936025619507}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D022661","descriptor_name":"RNA, Untranslated","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":7,"locations":[{"id":"doi:10.1093/nar/gks296","doi":"https://doi.org/10.1093/nar/gks296","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gks296","pdf_url":"https://academic.oup.com/nar/article-pdf/40/14/6391/7209776/gks296.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2418593","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3413108","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:22492512","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22492512","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3413108","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3413108/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.813.9240","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.813.9240","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/dd/a7/gks296.PMC3413108.pdf","raw_type":"text"},{"id":"pmh:oai:open-archive.highwire.org:nar:40/14/6391","doi":null,"is_oa":false,"landing_page_url":"http://nar.oxfordjournals.org/cgi/content/short/40/14/6391","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"mag:2184416402","doi":null,"is_oa":false,"landing_page_url":"https://www.researchgate.net/profile/Ahmad_Khalil4/publication/223973927_Emerging_functional_and_mechanistic_paradigms_of_mammalian_long_non-coding_RNAs/links/0deec527bfb64e5aaa000000.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.1093/nar/gks296","doi":"https://doi.org/10.1093/nar/gks296","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gks296","pdf_url":"https://academic.oup.com/nar/article-pdf/40/14/6391/7209776/gks296.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3414110853","display_name":"Identification and characterization of long noncoding RNAs in human melanomas","funder_award_id":"R03CA165184","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8651441853","display_name":"Identification of the molecular mechanism of miR-211 and its target genes in melanocytes and pigmented melanoma senescence and apoptosis","funder_award_id":"R21CA202197","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320320290","display_name":"University of Oxford","ror":"https://ror.org/052gg0110"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2146648170.pdf","grobid_xml":"https://content.openalex.org/works/W2146648170.grobid-xml"},"referenced_works_count":103,"referenced_works":["https://openalex.org/W201842558","https://openalex.org/W1535914077","https://openalex.org/W1546087563","https://openalex.org/W1567701663","https://openalex.org/W1597843712","https://openalex.org/W1686333409","https://openalex.org/W1965568102","https://openalex.org/W1968931043","https://openalex.org/W1969499463","https://openalex.org/W1969759955","https://openalex.org/W1970397315","https://openalex.org/W1973330264","https://openalex.org/W1973445288","https://openalex.org/W1977751039","https://openalex.org/W1977937947","https://openalex.org/W1977943782","https://openalex.org/W1979768717","https://openalex.org/W1985717866","https://openalex.org/W1986197409","https://openalex.org/W1986234964","https://openalex.org/W1989904037","https://openalex.org/W1990689171","https://openalex.org/W1992605446","https://openalex.org/W1999746344","https://openalex.org/W2000580034","https://openalex.org/W2000875411","https://openalex.org/W2001206796","https://openalex.org/W2001320007","https://openalex.org/W2001841820","https://openalex.org/W2007483233","https://openalex.org/W2013958859","https://openalex.org/W2015416439","https://openalex.org/W2016302314","https://openalex.org/W2016430576","https://openalex.org/W2017840637","https://openalex.org/W2020958409","https://openalex.org/W2023630351","https://openalex.org/W2024303499","https://openalex.org/W2030047242","https://openalex.org/W2035365585","https://openalex.org/W2037064308","https://openalex.org/W2037471476","https://openalex.org/W2038598202","https://openalex.org/W2038881844","https://openalex.org/W2039408641","https://openalex.org/W2039816251","https://openalex.org/W2040356607","https://openalex.org/W2043317822","https://openalex.org/W2047333953","https://openalex.org/W2051282896","https://openalex.org/W2051911149","https://openalex.org/W2052469034","https://openalex.org/W2053758959","https://openalex.org/W2058970225","https://openalex.org/W2059592231","https://openalex.org/W2059968749","https://openalex.org/W2062313490","https://openalex.org/W2065466457","https://openalex.org/W2067410483","https://openalex.org/W2069139855","https://openalex.org/W2071271349","https://openalex.org/W2071849521","https://openalex.org/W2081324839","https://openalex.org/W2087377443","https://openalex.org/W2089652064","https://openalex.org/W2091161969","https://openalex.org/W2094913989","https://openalex.org/W2096083625","https://openalex.org/W2096858457","https://openalex.org/W2099468911","https://openalex.org/W2104504930","https://openalex.org/W2107959716","https://openalex.org/W2110015307","https://openalex.org/W2116236561","https://openalex.org/W2117613120","https://openalex.org/W2118008449","https://openalex.org/W2121352589","https://openalex.org/W2122289183","https://openalex.org/W2124650740","https://openalex.org/W2126504590","https://openalex.org/W2128034264","https://openalex.org/W2129078669","https://openalex.org/W2130313087","https://openalex.org/W2130388134","https://openalex.org/W2134033103","https://openalex.org/W2134087142","https://openalex.org/W2134368004","https://openalex.org/W2135302954","https://openalex.org/W2137840425","https://openalex.org/W2139347946","https://openalex.org/W2143593381","https://openalex.org/W2144137532","https://openalex.org/W2145931730","https://openalex.org/W2146573461","https://openalex.org/W2147637490","https://openalex.org/W2150098952","https://openalex.org/W2153826038","https://openalex.org/W2156880688","https://openalex.org/W2160333540","https://openalex.org/W2169416332","https://openalex.org/W2170260159","https://openalex.org/W2171143303","https://openalex.org/W7096037588"],"related_works":["https://openalex.org/W2184416402","https://openalex.org/W2948236713","https://openalex.org/W2274744779","https://openalex.org/W984723080","https://openalex.org/W2129375421","https://openalex.org/W2067337865","https://openalex.org/W7154702583","https://openalex.org/W1990895545","https://openalex.org/W2550624495","https://openalex.org/W4308121154"],"abstract_inverted_index":{"The":[0],"recent":[1,50,89],"discovery":[2],"that":[3,102],"the":[4,74,93],"human":[5,123,136],"and":[6,41,66,72,97,112,125],"other":[7],"mammalian":[8],"genomes":[9],"produce":[10],"thousands":[11],"of":[12,36,63,68,95,100,114],"long":[13],"non-coding":[14],"RNAs":[15],"(lncRNAs)":[16],"raises":[17],"many":[18],"fascinating":[19],"questions.":[20],"These":[21],"mRNA-like":[22],"molecules,":[23],"which":[24],"lack":[25],"significant":[26],"protein-coding":[27],"capacity,":[28],"have":[29],"been":[30],"implicated":[31],"in":[32,56,91,122,135],"a":[33],"wide":[34],"range":[35],"biological":[37],"functions":[38,111],"through":[39],"diverse":[40,58],"as":[42,61,117],"yet":[43],"poorly":[44],"understood":[45],"molecular":[46],"mechanisms.":[47],"Despite":[48],"some":[49],"insights":[51,108],"into":[52,109],"how":[53],"lncRNAs":[54,96,119],"function":[55],"such":[57],"cellular":[59,69],"processes":[60],"regulation":[62],"gene":[64],"expression":[65],"assembly":[67],"structures,":[70],"by":[71],"large,":[73],"key":[75],"questions":[76],"regarding":[77],"lncRNA":[78],"mechanisms":[79,113],"remain":[80],"to":[81,105],"be":[82],"answered.":[83],"In":[84],"this":[85],"review,":[86],"we":[87,127],"discuss":[88,129],"advances":[90],"understanding":[92],"biology":[94],"propose":[98],"avenues":[99],"investigation":[101],"may":[103],"lead":[104],"fundamental":[106],"new":[107],"their":[110],"action.":[115],"Finally,":[116],"numerous":[118],"are":[120],"dysregulated":[121],"diseases":[124],"disorders,":[126],"also":[128],"potential":[130],"roles":[131],"for":[132],"these":[133],"molecules":[134],"health.":[137]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":18},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":22},{"year":2022,"cited_by_count":47},{"year":2021,"cited_by_count":61},{"year":2020,"cited_by_count":69},{"year":2019,"cited_by_count":52},{"year":2018,"cited_by_count":53},{"year":2017,"cited_by_count":64},{"year":2016,"cited_by_count":56},{"year":2015,"cited_by_count":53},{"year":2014,"cited_by_count":49},{"year":2013,"cited_by_count":48},{"year":2012,"cited_by_count":19}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}