{"id":"https://openalex.org/W2146571321","doi":"https://doi.org/10.1093/humrep/deq240","title":"Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma","display_name":"Cell proliferation effect of GnRH agonist on pathological lesions of women with endometriosis, adenomyosis and uterine myoma","publication_year":2010,"publication_date":"2010-09-09","ids":{"openalex":"https://openalex.org/W2146571321","doi":"https://doi.org/10.1093/humrep/deq240","mag":"2146571321","pmid":"https://pubmed.ncbi.nlm.nih.gov/20829343"},"language":"en","primary_location":{"id":"doi:10.1093/humrep/deq240","doi":"https://doi.org/10.1093/humrep/deq240","is_oa":false,"landing_page_url":"https://doi.org/10.1093/humrep/deq240","pdf_url":null,"source":{"id":"https://openalex.org/S127900037","display_name":"Human Reproduction","issn_l":"0268-1161","issn":["0268-1161","1460-2350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Reproduction","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://nagasaki-u.repo.nii.ac.jp/records/14537","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038790943","display_name":"Khaleque Newaz Khan","orcid":"https://orcid.org/0000-0002-9493-3340","observed_orcids":["https://orcid.org/0000-0002-9493-3340"]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"K. N. Khan","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto, Nagasaki, Japan. nemokhan@nagasaki-u.ac.jp","Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto, Nagasaki, Japan. nemokhan@nagasaki-u.ac.jp","institution_ids":["https://openalex.org/I43777268"]},{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan","institution_ids":["https://openalex.org/I43777268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084784158","display_name":"Michio Kitajima","orcid":"https://orcid.org/0000-0002-2661-9034","observed_orcids":["https://orcid.org/0000-0002-2661-9034"]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M. Kitajima","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan","institution_ids":["https://openalex.org/I43777268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113945662","display_name":"Koichi Hiraki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K. Hiraki","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan","institution_ids":["https://openalex.org/I43777268"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087253171","display_name":"Akira Fujishita","orcid":"https://orcid.org/0000-0002-6472-1291","observed_orcids":["https://orcid.org/0000-0002-6472-1291"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Fujishita","raw_affiliation_strings":["Nagasaki Saiseikai Hospital, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nagasaki Saiseikai Hospital, Nagasaki, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052768130","display_name":"Masahiro Nakashima","orcid":"https://orcid.org/0000-0002-9036-8735","observed_orcids":["https://orcid.org/0000-0002-9036-8735"]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]},{"id":"https://openalex.org/I4405285995","display_name":"Atomic Bomb Disease Institute, Nagasaki University","ror":"https://ror.org/00wc6zv93","country_code":"JP","type":"facility","lineage":["https://openalex.org/I43777268","https://openalex.org/I4405285995"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M. Nakashima","raw_affiliation_strings":["Department of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Tumor and Diagnostic Pathology, Atomic Bomb Disease Institute, Nagasaki University, Nagasaki, Japan","institution_ids":["https://openalex.org/I43777268","https://openalex.org/I4405285995"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T. Ishimaru","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405253956","display_name":"Sasebo Chuo Hospital","ror":"https://ror.org/018bw0k35","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405253956"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T. Ishimaru","raw_affiliation_strings":["Sasebo Chuo Hospital, Nagasaki, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sasebo Chuo Hospital, Nagasaki, Japan","institution_ids":["https://openalex.org/I4405253956"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037614729","display_name":"Hideaki Masuzaki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I43777268","display_name":"Nagasaki University","ror":"https://ror.org/058h74p94","country_code":"JP","type":"education","lineage":["https://openalex.org/I43777268"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"H. Masuzaki","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan","institution_ids":["https://openalex.org/I43777268"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5038790943"],"corresponding_institution_ids":["https://openalex.org/I43777268"],"apc_list":{"value":4097,"currency":"EUR","value_usd":4630},"apc_paid":null,"fwci":2.4157,"has_fulltext":false,"cited_by_count":135,"citation_normalized_percentile":{"value":0.87421431,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"25","issue":"11","first_page":"2878","last_page":"2890"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10935","display_name":"Endometriosis Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10935","display_name":"Endometriosis Research and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10989","display_name":"Uterine Myomas and Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gnrh-agonist","display_name":"GnRH agonist","score":0.8920000195503235},{"id":"https://openalex.org/keywords/gnrh-receptor","display_name":"GnRH receptor","score":0.9020000100135803},{"id":"https://openalex.org/keywords/endometriosis","display_name":"endometriosis","score":0.9810000061988831},{"id":"https://openalex.org/keywords/adenomyosis","display_name":"adenomyosis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/uterine-fibroids","display_name":"uterine fibroids","score":0.9430000185966492},{"id":"https://openalex.org/keywords/endometrioma","display_name":"endometrioma","score":0.9269999861717224},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.8960000276565552},{"id":"https://openalex.org/keywords/ki-67","display_name":"Ki-67","score":0.8999999761581421},{"id":"https://openalex.org/keywords/endometrium","display_name":"endometrium","score":0.6430000066757202},{"id":"https://openalex.org/keywords/menstrual-cycle","display_name":"menstrual cycle","score":0.6449999809265137},{"id":"https://openalex.org/keywords/antiproliferative-activity","display_name":"antiproliferative activity","score":0.7879999876022339}],"concepts":[{"id":"https://openalex.org/C2779166600","wikidata":"https://www.wikidata.org/wiki/Q2012569","display_name":"Adenomyosis","level":3,"score":0.8157171010971069},{"id":"https://openalex.org/C2779522080","wikidata":"https://www.wikidata.org/wiki/Q205764","display_name":"Endometriosis","level":2,"score":0.6783227920532227},{"id":"https://openalex.org/C2776817873","wikidata":"https://www.wikidata.org/wiki/Q15316535","display_name":"GNRHR","level":5,"score":0.6225868463516235},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5985321998596191},{"id":"https://openalex.org/C2779742232","wikidata":"https://www.wikidata.org/wiki/Q839508","display_name":"Endometrium","level":2,"score":0.5093146562576294},{"id":"https://openalex.org/C2910938049","wikidata":"https://www.wikidata.org/wiki/Q7249605","display_name":"Proliferation index","level":3,"score":0.4590185880661011},{"id":"https://openalex.org/C2776606343","wikidata":"https://www.wikidata.org/wiki/Q5376361","display_name":"Endometrial biopsy","level":3,"score":0.44720518589019775},{"id":"https://openalex.org/C2779066055","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Uterus","level":2,"score":0.42932701110839844},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.3556783199310303},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.34221962094306946},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3415318727493286},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33378204703330994},{"id":"https://openalex.org/C2778894405","wikidata":"https://www.wikidata.org/wiki/Q318896","display_name":"Gonadotropin-releasing hormone","level":4,"score":0.2573930025100708},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.14932504296302795},{"id":"https://openalex.org/C2778575703","wikidata":"https://www.wikidata.org/wiki/Q50265477","display_name":"Luteinizing hormone","level":3,"score":0.14878630638122559}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004715","descriptor_name":"Endometriosis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004715","descriptor_name":"Endometriosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007889","descriptor_name":"Leiomyoma","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007889","descriptor_name":"Leiomyoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007987","descriptor_name":"Gonadotropin-Releasing Hormone","qualifier_ui":"Q000819","qualifier_name":"agonists","is_major_topic":true},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011966","descriptor_name":"Receptors, LHRH","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D014594","descriptor_name":"Uterine Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014594","descriptor_name":"Uterine Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016729","descriptor_name":"Leuprolide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D019394","descriptor_name":"Ki-67 Antigen","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/humrep/deq240","doi":"https://doi.org/10.1093/humrep/deq240","is_oa":false,"landing_page_url":"https://doi.org/10.1093/humrep/deq240","pdf_url":null,"source":{"id":"https://openalex.org/S127900037","display_name":"Human Reproduction","issn_l":"0268-1161","issn":["0268-1161","1460-2350"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Reproduction","raw_type":"journal-article"},{"id":"pmid:20829343","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20829343","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human reproduction (Oxford, England)","raw_type":"Journal Article"},{"id":"pmh:oai:irdb.nii.ac.jp:01160:0004784341","doi":null,"is_oa":true,"landing_page_url":"https://nagasaki-u.repo.nii.ac.jp/records/14537","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Human reproduction (Oxford, England)","raw_type":"journal article"},{"id":"pmh:oai:naosite.lb.nagasaki-u.ac.jp:10069/26616","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10069/26616","pdf_url":null,"source":{"id":"https://openalex.org/S4306400113","display_name":"Nagasaki University's Academic Output SITE (Nagasaki University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43777268","host_organization_name":"Nagasaki University","host_organization_lineage":["https://openalex.org/I43777268"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":null}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:01160:0004784341","doi":null,"is_oa":true,"landing_page_url":"https://nagasaki-u.repo.nii.ac.jp/records/14537","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Human reproduction (Oxford, England)","raw_type":"journal article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W1573481489","https://openalex.org/W1867673000","https://openalex.org/W1964707056","https://openalex.org/W1970703629","https://openalex.org/W1976947803","https://openalex.org/W1978598833","https://openalex.org/W1981769498","https://openalex.org/W2001135993","https://openalex.org/W2013444999","https://openalex.org/W2017209863","https://openalex.org/W2018739526","https://openalex.org/W2022954058","https://openalex.org/W2029222193","https://openalex.org/W2029222763","https://openalex.org/W2051917498","https://openalex.org/W2056847739","https://openalex.org/W2063229043","https://openalex.org/W2064264164","https://openalex.org/W2078230286","https://openalex.org/W2082048636","https://openalex.org/W2088814866","https://openalex.org/W2107713440","https://openalex.org/W2121072799","https://openalex.org/W2122706104","https://openalex.org/W2138880216","https://openalex.org/W2154111336","https://openalex.org/W2158274066","https://openalex.org/W2158765933","https://openalex.org/W2171733571","https://openalex.org/W2607215535"],"related_works":["https://openalex.org/W2171733571","https://openalex.org/W2122009641","https://openalex.org/W1973704946","https://openalex.org/W2391040571","https://openalex.org/W2046062301","https://openalex.org/W2114697800","https://openalex.org/W2064264164","https://openalex.org/W2003275951","https://openalex.org/W2379401214","https://openalex.org/W2359542770"],"abstract_inverted_index":{"BACKGROUND:":[0],"We":[1],"recently":[2],"demonstrated":[3],"the":[4,36,180,183,192,219,265],"effect":[5,32,123,258],"of":[6,27,33,38,46,62,92,111,124,191,198,221,239,259,267,274],"gonadotrophin-releasing":[7],"hormone":[8],"agonist":[9],"(GnRHa)":[10],"on":[11,35,126],"tissue":[12,114,237],"inflammation,":[13],"angiogenesis":[14],"and":[15,20,31,43,59,77,89,97,107,148,154,158,165,174,227,246],"apoptosis":[16],"in":[17,94,113,142,162,182,203,209,243,264],"endometriosis,":[18,67,172,244],"adenomyosis":[19,76,173,245],"uterine":[21,81,175,247],"myoma.":[22,176,248],"Here,":[23],"we":[24],"investigated":[25],"expression":[26,178,238],"GnRH":[28],"receptors":[29],"(GnRHRs)":[30],"GnRHa":[34,125,216,260],"proliferation":[37,128,138,220],"cells":[39,96,222],"derived":[40,145,168,223],"from":[41,57,146,169,224],"endometria":[42,61,164,226],"pathological":[44,166,228],"lesions":[45,58,167,207,229],"women":[47,64,69,74,79,170],"with":[48,65,70,75,80,171,188,215,232,271],"these":[49,268],"reproductive":[50,269],"diseases.":[51],"METHODS:":[52],"Biopsy":[53],"specimens":[54,144],"were":[55,99,160,201],"collected":[56],"corresponding":[60],"35":[63,73],"pelvic":[66],"45":[68],"ovarian":[71],"endometrioma,":[72],"56":[78],"myoma":[82],"during":[83],"laparoscopy":[84],"or":[85],"laparotomy.":[86],"The":[87,109,121,135],"gene":[88],"protein":[90],"expressions":[91],"GnRHR":[93,112,177,199,240],"eutopic/ectopic":[95],"tissues":[98],"examined":[100,130],"by":[101,117,131],"reverse":[102],"transcriptase-polymerase":[103],"chain":[104],"reaction":[105],"(RT-PCR)":[106],"immunohistochemistry.":[108],"immunoreactivity":[110],"was":[115,129,140,179,241],"analysed":[116,141],"quantitative-histogram":[118],"(Q-H)":[119],"scores.":[120],"exogenous":[122],"cell":[127,137],"5-bromo-2-deoxyuridine":[132],"incorporation":[133],"assay.":[134],"Ki-67-immunoreactive":[136],"index":[139],"biopsy":[143],"GnRHa-treated":[147],"-non-treated":[149],"women.":[150],"RESULTS:":[151],"Types":[152],"I":[153],"II":[155],"GnRHRs":[156],"mRNA":[157],"proteins":[159],"expressed":[161],"eutopic":[163],"highest":[181],"menstrual":[184,193],"phase":[185],"when":[186,230],"compared":[187,231],"other":[189,210],"phases":[190],"cycle.":[194],"Higher":[195],"Q-H":[196],"scores":[197],"immunoreaction":[200],"found":[202],"blood-filled":[204],"opaque":[205],"red":[206],"than":[208],"peritoneal":[211],"lesions.":[212],"Exogenous":[213],"treatment":[214],"significantly":[217],"suppressed":[218],"respective":[225],"GnRHa-non-treated":[233],"cells.":[234],"CONCLUSIONS:":[235],"Local":[236],"detected":[242],"In":[249],"addition":[250],"to":[251],"a":[252,255],"hypo-estrogenic":[253],"effect,":[254],"direct":[256],"anti-proliferative":[257],"may":[261],"be":[262],"involved":[263],"regression":[266],"diseases":[270],"consequent":[272],"remission":[273],"clinical":[275],"symptoms.":[276]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":19},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":19},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}